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公开(公告)号：US4204604A
公开(公告)日：1980-05-27
申请号：US34827
申请日：1979-04-30
CPC分类号： B65D51/18 , B65D2251/0015 , B65D2251/0078
摘要： An improvement in a closure system for containers in which a cap member sealed at its base to an annular flange about the neck of the container is removeable by a cutting ring. The cap includes an upwardly projecting brim at the base separated from the side wall of the cap to provide an annular groove. The groove has at least one tapered recess. The cutting ring which can be positioned around the side wall of the cap has at least one depending tab with an inwardly directed sharpened projection. Normally, the tab rests in the recess of the groove. Upon rotation of the cutting ring, the tab is forced inwardly causing the sharpened projection to sever the side wall of the closure.
摘要翻译： 对于容器的封闭系统的改进，其中在其基部处密封在围绕容器颈部的环形凸缘的帽构件可被切割环移除。 盖子包括在基座的与盖的侧壁分离的向上突出的边缘以提供环形槽。 凹槽具有至少一个锥形凹槽。 可以围绕盖的侧壁定位的切割环具有至少一个具有向内指向的锐化突起的悬垂突出部。 通常，突片位于凹槽的凹槽中。 当切割环旋转时，突片被向内推动，使得尖锐的突起切断封闭件的侧壁。
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公开(公告)号：US4207988A
公开(公告)日：1980-06-17
申请号：US40002
申请日：1979-05-18
CPC分类号： A61J1/1406 , B65D41/32 , B65D51/002 , B65D51/20 , B65D2251/0015 , B65D2251/009
摘要： Improvements in inner and outer closures for containers are disclosed. The outer closure is characterized by a cap member having a top wall, a side wall and a base adapted for sealing to the neck of a container. Two score lines extend across the top wall with finger gripping means attached at the apex where the two score lines meet. One score line extends down the side wall to connect with a third score line near the base which extends completely around the cap. The other score line extends down the side wall to an intermediate position and diverges away and terminates a short distance from the one score line. By pulling on the finger gripping means, the entire cap member above the third score line is removed in one piece. The inner closure comprises a plastic member sealed at its periphery to the mouth of the neck and includes a vertically aligned spike-entry port and an additive port which is oriented at an angle away from the entry port. The spike-entry port in an improved version comprises a spike-retaining collar which is joined to the body of the closure by a downward sloping web section which functions so as to cause the collar to grip an inserted spike more firmly to prevent accidental withdrawal of the spike. An improved version of an inner closure and container neck is also disclosed which includes particulate retaining means to prevent particulates formed during frictional welding of the closure to the neck from entering the container.
摘要翻译： 披露了容器内外封闭件的改进。 外盖的特征在于盖构件具有顶壁，侧壁和适于密封容器颈部的底座。 两条划线穿过顶壁延伸，手指夹紧装置连接在两条刻痕线相交的顶点处。 一个刻痕线沿着侧壁向下延伸，以与靠近底座的第三刻痕线连接，其完全围绕盖延伸。 另一个刻痕线从侧壁向下延伸到中间位置，并分离开并终止与一个刻痕线的短距离。 通过拉动手指夹持装置，将整个帽部件在第三刻痕线上方一体地移除。 内封闭件包括在其周边密封在颈部口部的塑料构件，并且包括垂直对准的钉入口和附加端口，其以远离入口的角度定向。 改进版本的钉入口包括钉保持套环，其通过向下倾斜的腹板部分连接到闭合件的本体，该部分的功能是使得套环更牢固地夹持插入的尖头以防止意外撤出 尖峰 还公开了内封闭和容器颈部的改进型式，其包括颗粒保持装置，以防止在闭合件对颈部的摩擦焊接期间形成的微粒进入容器。
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公开(公告)号：US06685700B2
公开(公告)日：2004-02-03
申请号：US09992734
申请日：2001-11-13
IPC分类号： A61B1804
CPC分类号： A61B18/1482 , A61B18/1477 , A61B2018/00702 , A61B2018/00875 , A61B2018/1425 , A61B2018/143 , A61B2018/1475
摘要： Methods for heating tissue by delivering radio frequency energy through tissue electrodes comprise controlling energy delivery so that an abrupt increase in impedance between the electrodes and the tissue is observed, typically in the form of an abrupt decrease in power delivered to the electrodes. The power at which the impedance increases and/or the time required to induce such an increase in impedance, are relied on to determine acceptable ranges to achieve a maximum sustainable delivery of radio frequency energy to the tissue consistent with complete, rapid, and uniform heating of the tissue.
摘要翻译： 通过组织电极传送射频能量来加热组织的方法包括控制能量输送，从而观察到电极和组织之间的阻抗的突然增加，通常以递送至电极的功率的突然减小的形式。 依赖于阻抗增加的功率和/或引起阻抗增加所需的时间的功率来确定可接受的范围，以实现符合完整，快速和均匀加热的无线电频率能量到组织的最大可持续传递 的组织。
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公开(公告)号：US5433708A
公开(公告)日：1995-07-18
申请号：US73639
申请日：1993-06-07
IPC分类号： A61B17/00 , A61B17/12 , A61B17/22 , A61B18/00 , A61B18/04 , A61B18/08 , A61B19/00 , A61F7/00 , A61F7/12 , A61M1/00 , A61B17/36
CPC分类号： A61B18/082 , A61B2017/00084 , A61B2017/00092 , A61B2017/00292 , A61B2017/1205 , A61B2017/22038 , A61B2018/00095 , A61B2018/00422 , A61B2018/044 , A61B2018/046 , A61B2090/3933 , A61B2218/002 , A61F2007/0059 , A61F7/12
摘要： A thermal ablation catheter includes an elongate body member having a heating element disposed over a predetermined length of its distal end. The heating element is suspended away from an exterior surface of the elongate member to form a circulation region thereunder. Thermally conductive fluid can be introduced through a lumen in the elongate member and distributed within the circulation region to improve heat transfer. The catheter is used to introduce the thermally conductive medium to a hollow body organ where the heating element raises the temperature of the medium sufficiently to induce injury to the lining of the organ. Optionally, an introducer sheath having an expandable cage at its distal end may be used in combination with a thermal ablation catheter. The expandable cage helps center the heating element on the catheter within the body organ and prevents direct contact between the heating element and the wall of the organ. Heat transfer and temperature uniformity can be enhanced by inducing an oscillatory flow of the heat transfer medium through the catheter while heat is being applied.
摘要翻译： 热消融导管包括细长本体构件，其具有设置在其远端的预定长度上的加热元件。 加热元件从细长构件的外表面悬挂以形成其下的循环区域。 导热流体可以通过细长构件中的内腔引入并且分布在循环区域内以改善热传递。 导管用于将导热介质引入中空体器官，其中加热元件足以使培养基的温度升高以引起对器官衬里的损伤。 可选地，在其远端具有可扩张的保持架的导引套可与热消融导管组合使用。 可膨胀笼可帮助将加热元件放置在身体器官内的导管上，并防止加热元件与器官壁之间的直接接触。 通过在施加热量时通过导管引导传热介质的振荡流，可以增强热传递和温度均匀性。
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公开(公告)号：US5100388A
公开(公告)日：1992-03-31
申请号：US529077
申请日：1990-05-25
申请人： Robert S. Behl , Colin J. Nichols
发明人： Robert S. Behl , Colin J. Nichols
IPC分类号： A61F7/12 , A61B17/22 , A61B18/00 , A61B18/04 , A61B18/08 , A61B18/28 , A61B19/00 , A61F7/02 , A61M3/02
CPC分类号： A61B18/082 , A61B18/28 , A61B2017/22054 , A61B2018/00095 , A61B2018/046 , A61B2090/3933 , A61B2090/3962 , A61B2218/002 , A61F2007/0298 , A61M3/0279
摘要： Hollow body organs, such as the gallbladder, may be ablated by introducing a substantially unheated thermally conductive medium to the interior of the organ. The thermally conductive medium is then heated to a temperature sufficient to necrose the endothelial lining or mucous membrane of the organ. After the lining or membrane has necrosed, the interior of the organ will fibrose over time and the organ will eventually be resorbed by the body. A catheter useful in performing the ablation method comprises an elongate member having a heating element at its distal tip. The catheter will include at least one lumen for delivering the thermally conductive medium to the interior of the hollow body organ, and the heating means is used to raise the temperature of the thermally conductive medium after it has been delivered. Optionally, the catheter may include one or more inflatable balloons which facilitate sealing of the hollow body organ to inhibit leakage of the thermally conductive medium during the treatment process. The heating element may comprise a single point heat source or a heat source distributed over a fixed length. Distributed heat sources may further be adapted to provide for a non-linear heat flux delivery pattern.
摘要翻译： 可以通过将基本上未加热的导热介质引入器官内部而消融诸如胆囊的中空身体器官。 然后将导热介质加热到足以使器官的内皮衬里或粘膜破坏的温度。 衬里或膜已经坏死后，器官的内部会随着时间的推移而变形，器官最终将被身体吸收。 可用于执行消融方法的导管包括在其远端处具有加热元件的细长构件。 导管将包括用于将导热介质输送到中空体器官内部的至少一个内腔，并且加热装置用于在导热介质输送之后提高导热介质的温度。 任选地，导管可以包括一个或多个可充气球囊，其有利于中空体器官的密封，以防止在处理过程中导热介质的泄漏。 加热元件可以包括分布在固定长度上的单点热源或热源。 分布式热源可以进一步适于提供非线性热通量输送模式。
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公开(公告)号：US5954717A
公开(公告)日：1999-09-21
申请号：US936294
申请日：1997-09-25
CPC分类号： A61B18/1477
摘要： Methods for heating tissue by delivering radio frequency energy through tissue electrodes comprise controlling energy delivery so that an abrupt increase in impedance between the electrodes and the tissue is observed, typically in the form of an abrupt decrease in power delivered to the electrodes. The power at which the impedance increases and/or the time required to induce such an increase in impedance, are relied on to determine acceptable ranges to achieve a maximum sustainable delivery of radio frequency energy to the tissue consistent with complete, rapid, and uniform heating of the tissue.
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公开(公告)号：US5250033A
公开(公告)日：1993-10-05
申请号：US967602
申请日：1992-10-28
CPC分类号： A61M25/0668
摘要： A peel-away introducer sheath includes a tube sheath having a splittable handle at its proximal end. A gas or liquid sealing valve or other fitting is secured to a proximal face of the handle and includes an axial passage typically having a diameter approximately equal to the lumen diameter of the sheath. The valve includes a threaded connector which is received in a counter bore formed in the handle. In this way, the sheath may be split apart leaving only the valve or other fitting in place on a catheter passing therethrough.
摘要翻译： 剥离导引鞘包括在其近端具有可分开的手柄的管鞘。 气体或液体密封阀或其他配件固定到手柄的近侧面，并且包括通常具有大约等于护套的内腔直径的直径的轴向通道。 阀包括螺纹连接器，其被接收在形成在手柄中的反向孔中。 以这种方式，护套可以分开，仅将阀门或其他配件安置在穿过其中的导管上的适当位置。
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公开(公告)号：US5160325A
公开(公告)日：1992-11-03
申请号：US644970
申请日：1991-01-22
CPC分类号： A61M25/003 , A61M25/0032 , A61M25/0075 , A61M25/01 , A61M25/0102
摘要： Catheter tubes of elastomeric material having novel lumen shapes which prevent occlusion and accommodate continued liquid flow even when kinked. Also, catheter tube slit valves are disclosed, the walls of which are not chemically weakened. Symmetrical and asymmetrical versions of said slit valves are disclosed. Combinations of highly reliable slit valves and catheter tubes are disclosed. Independently operable multi-lumen catheter assemblies of synthetic material, such as silicone rubber are disclosed, wherein the distal end of each lumen is normally closed by a three-position slit valve formed in a catheter tube covering. Multi-lumen catheters, and related methods, are also disclosed wherein the lumens are internal at the proximal and distal ends of the catheter tube but comprise separate tubes in between whereby, following placement of the distal end of the catheter tube in the body cavity of a patient, the unified proximal end of the tube is manipulated, sometimes subcutaneously, with the ultimately exposed tubes being thereafter severed and each equipped with a hub at a convenient exposed body site for selective independent passage of influent and effluent liquid along each lumen.
摘要翻译： 具有新颖的管腔形状的弹性材料的导管管，其防止堵塞并且即使在扭结时也适应持续的液体流动。 此外，公开了导管管狭缝阀，其壁不被化学地削弱。 公开了所述狭缝阀的对称和非对称形式。 公开了高度可靠的狭缝阀和导管的组合。 公开了诸如硅橡胶的合成材料的独立可操作的多腔导管组件，其中每个腔的远端通常由形成在导管套管中的三位置狭缝阀封闭。 还公开了多腔导管以及相关方法，其中腔内部位于导管管的近端和远端，但在其间包括分开的管，其中，在将导管管的远端放置在体腔内 患者，管的统一近端被操纵，有时是皮下的，最后暴露的管随后被切断，并且每个都在方便的暴露的身体部位装备有轮毂，用于沿着每个管腔选择性地独立地通过流入物和流出液体。
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公开(公告)号：US06358246B1
公开(公告)日：2002-03-19
申请号：US09344822
申请日：1999-06-25
IPC分类号： A61B1804
CPC分类号： A61B18/1482 , A61B18/1477 , A61B2018/00702 , A61B2018/00875 , A61B2018/1425 , A61B2018/143 , A61B2018/1475
摘要： Methods for heating tissue by delivering radio frequency energy through tissue electrodes comprise controlling energy delivery so that an abrupt increase in impedance between the electrodes and the tissue is observed, typically in the form of an abrupt decrease in power delivered to the electrodes. The power at which the impedance increases and/or the time required to induce such an increase in impedance, are relied on to determine acceptable ranges to achieve a maximum sustainable delivery of radio frequency energy to the tissue consistent with complete, rapid, and uniform heating of the tissue.
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公开(公告)号：US5542928A
公开(公告)日：1996-08-06
申请号：US266037
申请日：1994-06-27
IPC分类号： A61B17/00 , A61B17/12 , A61B17/22 , A61B18/00 , A61B18/04 , A61B18/08 , A61B19/00 , A61F7/00 , A61F7/12 , A61M1/00 , A61B17/36
CPC分类号： A61B18/082 , A61B2017/00084 , A61B2017/00092 , A61B2017/00292 , A61B2017/22038 , A61B2017/4216 , A61B2018/00095 , A61B2018/00422 , A61B2018/044 , A61B2018/046 , A61B2090/3933 , A61B2218/002 , A61F2007/0059 , A61F7/12 , A61M1/0084
摘要： A thermal ablation catheter includes an elongate body member having a heating element disposed over a predetermined length of its distal end or within an axial lumen. The heating element is suspended away from an exterior surface of the elongate member to form a circulation region thereunder. Alternatively, the heating element is distributed over some or all of the axial lumen. Thermally conductive fluid can be introduced through the lumen in the elongate member and into the circulation region to effect heat transfer. The catheter is used to introduce the thermally conductive medium to a hollow body organ where the heating element raises the temperature of the medium sufficiently to induce injury to the lining of the organ. Optionally, an expandable cage in the catheter or on an associated introducer sheath may be used in combination with a thermal ablation catheter. The expandable cage helps center the heating element on the catheter within the body organ and prevents direct contact between the heating element and the wall of the organ. When disposed on the catheter, the cage can be useful to position a flow directing element attached to the flow delivery lumen of the catheter. Heat transfer and temperature uniformity can be enhanced by inducing an oscillatory flow of the heat transfer medium through the catheter while heat is being applied.
摘要翻译： 热消融导管包括细长本体构件，其具有设置在其远端的预定长度上或在轴向腔内的加热元件。 加热元件从细长构件的外表面悬挂以形成其下的循环区域。 或者，加热元件分布在轴向内腔的一些或全部上。 导热流体可以通过细长构件中的内腔引入循环区域以实现热传递。 导管用于将导热介质引入中空体器官，其中加热元件足以使培养基的温度升高以引起对器官衬里的损伤。 任选地，导管中或相关导引鞘上的可膨胀笼可以与热消融导管结合使用。 可膨胀笼可帮助将加热元件放置在身体器官内的导管上，并防止加热元件与器官壁之间的直接接触。 当设置在导管上时，保持架可用于定位附接到导管的流动输送腔的流动引导元件。 通过在施加热量时通过导管引导传热介质的振荡流，可以增强热传递和温度均匀性。
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