公开(公告)号：US07695492B1

公开(公告)日：2010-04-13

申请号：US10462065

申请日：2003-06-12

申请人： Mark Ashby ,  Andrew H. Cragg ,  Luis R. Urquidi ,  Eduardo Chi Sing

发明人： Mark Ashby ,  Andrew H. Cragg ,  Luis R. Urquidi ,  Eduardo Chi Sing

IPC分类号： A61M5/00

CPC分类号： A61B17/0057 ,  A61B2017/00637 ,  A61B2017/00672 ,  A61B2090/062

摘要： The present invention provides for an apparatus to locate a blood vessel puncture having a bleed back entrance port near a first end, a bleed back exit port near a second end; and a lumen extending between the bleed back entrance port and the bleed back exit port, wherein said bleed back entrance port has a diameter substantially equal to or greater than the lumen diameter. The present invention further provides for a method for locating a blood vessel puncture by inserting a locator into a blood vessel lumen, the locator having a bleed back entrance port at a first end, a bleed back exit port at a second end, and a finger adjacent the bleed back entrance port, observing a blood flow out of the bleed back exit port, and withdrawing the locator out of the blood vessel lumen until the finger contacts the blood vessel wall.

摘要翻译： 本发明提供一种装置，用于定位在第一端附近具有排泄口入口的血管穿刺，靠近第二端的排出口; 以及在所述排泄口入口和所述排泄口出口之间延伸的内腔，其中所述排泄口入口具有基本上等于或大于所述管腔直径的直径。 本发明还提供一种通过将定位器插入血管内腔来定位血管穿刺的方法，所述定位器在第一端具有排出口入口，在第二端具有排出口，并且在手指 邻近排出口入口，观察从出血口出口的血液流出，并将定位器从血管腔排出，直到手指接触血管壁。

公开(公告)号：US07201725B1

公开(公告)日：2007-04-10

申请号：US10069107

申请日：2000-09-25

申请人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby ,  Eduardo Chi Sing

发明人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby ,  Eduardo Chi Sing

IPC分类号： A61B5/117 ,  A61B5/103

CPC分类号： A61B5/1076 ,  A61B5/489 ,  A61B17/0057 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00672 ,  A61B2090/036

摘要： A device for determining the depth of an incision from the epidermal layer to a puncture in a blood vessel in which the device includes an elongated member which has a lumen extending from a distal end to a proximal end. The distal end of the elongated member is configured to locate the blood vessel. After the device locates the blood vessel, a depth indicator is positioned to mark the depth of the blood vessel. In one embodiment, the elongated member includes a tapering interior surface which can receive a portion of the blood vessel. An extending control member may extend from the device at the distal end wherein the extending control member enters the blood vessel before the device locates the vessel. Fluid from the blood vessel enters the extending member through a vent hole and exits through an opening at the proximal end of the device, thereby providing a user with visual feedback that the device is moving in the desired direction toward the blood vessel.

摘要翻译： 一种用于确定从表皮层切割到血管穿刺深度的装置，其中该装置包括具有从远端延伸到近端的内腔的细长构件。 细长构件的远端构造成定位血管。 在设备定位血管之后，定位深度指示器以标记血管的深度。 在一个实施例中，细长构件包括可容纳血管的一部分的锥形内表面。 扩展控制构件可以在远端处的装置延伸，其中延伸的控制构件在装置定位血管之前进入血管。 来自血管的流体通过通气孔进入延伸构件，并通过设备近端的开口离开，从而为使用者提供视觉反馈，使得装置沿着期望的方向朝向血管运动。

公开(公告)号：US06440151B1

公开(公告)日：2002-08-27

申请号：US09589036

申请日：2000-06-06

申请人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

发明人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

IPC分类号： A61B1704

CPC分类号： A61B17/0057 ,  A61B10/0233 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00654

摘要： A system including an adaptor and a syringe is used for facilitating hemostasis of a biopsy tract or other puncture wound by injection of an absorbable sponge in a hydrated state into the wound. The adaptor includes a tapered lumen for hydrating and compressing the relatively large absorbable sponge for delivery through a relatively small cannula, such as a biopsy needle. The hydrated absorbable sponge is injected through the biopsy needle into the biopsy tract by fluid. The implanted absorbable sponge facilitates hemostasis at the biopsy site or other puncture wound and minimizes the chance of internal bleeding. The absorbable sponge material is absorbed by the body over time.

摘要翻译： 包括适配器和注射器的系统用于通过将水合状态的可吸收海绵注入伤口来促进穿刺活检管或其它穿刺的止血。 适配器包括锥形内腔，用于水合和压缩相对较大的可吸收海绵，以通过相对小的插管（例如活检针）递送。 将水合吸收海绵通过活检针注射入活检管内。 植入的可吸收海绵有助于活检部位或其他穿刺伤口止血，并最大限度地减少内部出血的机会。 可吸收的海绵材料随着时间的过去被身体吸收。

公开(公告)号：US08696702B2

公开(公告)日：2014-04-15

申请号：US12606526

申请日：2009-10-27

申请人： Andrew H. Cragg ,  Mark Ashby

发明人： Andrew H. Cragg ,  Mark Ashby

IPC分类号： A61B17/00

CPC分类号： A61B17/0057 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2090/062

摘要： A method of facilitating hemostasis of a blood vessel puncture. The method includes the steps of inserting a tubular device into a puncture in a blood vessel to establish access to the blood vessel, providing a vessel closure system around the tubular device, introducing a hemostatic material into a space between the tubular device and vessel closure system, and delivering the hemostatic material adjacent to the puncture to facilitate hemostasis of the puncture.

摘要翻译： 促进血管穿刺止血的方法。 该方法包括以下步骤：将管状装置插入到血管中的穿刺中以建立对血管的通路，在管状装置周围提供容器封闭系统，将止血材料引入管状装置和血管封闭系统之间的空间 并且将止血材料输送到穿刺附近以促进穿刺止血。

公开(公告)号：US06610026B2

公开(公告)日：2003-08-26

申请号：US09810931

申请日：2001-03-16

申请人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

发明人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

IPC分类号： A61B1704

CPC分类号： A61M37/0069 ,  A61B17/0057 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00898 ,  A61F2013/00463 ,  A61M31/00 ,  A61M37/00

摘要： A method of hydrating a sponge material for delivery to a body. The method includes the steps of placing a dry piece of sponge in a container at a first pressure. A hydrating fluid is then introduced into the container to hydrate the sponge. The pressure within the container is changed between the first pressure and a second pressure. At least a portion of the hydrating fluid is removed from the sponge, and the sponge is delivered to a bodily site.

摘要翻译： 将海绵材料保湿以递送到身体的方法。 该方法包括以干燥的海绵放置在第一压力的容器中的步骤。 然后将水合流体引入容器中以使海绵水合。 容器内的压力在第一压力和第二压力之间变化。 从海绵中去除至少一部分水合流体，将海绵输送到身体部位。

公开(公告)号：US06440153B2

公开(公告)日：2002-08-27

申请号：US09953395

申请日：2001-09-14

申请人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

发明人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

IPC分类号： A61B1708

CPC分类号： A61B17/0057 ,  A61B10/0233 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00654

摘要： A system including an adaptor and a syringe is used for facilitating hemostasis of a biopsy tract or other puncture wound by delivery of an absorbable sponge in a hydrated state into the wound. The adaptor includes a tapered lumen for hydrating and compressing the relatively large absorbable sponge for delivery through a relatively small cannula, such as a biopsy needle. The hydrated absorbable sponge is injected through the biopsy needle into the biopsy tract by fluid. Alternatively, the sponge may be delivered to the biopsy needle by injection of fluid and then delivered to the biopsy tract by a plunger or stylet. The implanted absorbable sponge facilitates hemostasis at the biopsy site or other puncture wound and minimizes the chance of internal bleeding. The absorbable sponge material is absorbed by the body over time.

摘要翻译： 包括适配器和注射器的系统用于促进通过将水合状态的可吸收海绵递送到伤口中来伤口活检管或其他穿刺的止血。 适配器包括锥形内腔，用于水合和压缩相对较大的可吸收海绵，以通过相对小的插管（例如活检针）递送。 将水合吸收海绵通过活检针注射入活检管内。 或者，可以通过注射流体将海绵递送到活检针，然后通过柱塞或通管针递送到活检管道。 植入的可吸收海绵有助于活检部位或其他穿刺伤口止血，并最大限度地减少内部出血的机会。 可吸收的海绵材料随着时间的过去被身体吸收。

公开(公告)号：US07875043B1

公开(公告)日：2011-01-25

申请号：US11008748

申请日：2004-12-08

申请人： Mark Ashby ,  Roy D. Bertolet ,  Tin T. Tran ,  Andrew H. Cragg

发明人： Mark Ashby ,  Roy D. Bertolet ,  Tin T. Tran ,  Andrew H. Cragg

IPC分类号： A61B17/04

CPC分类号： D04G1/00 ,  A61B17/0057 ,  A61B17/0469 ,  A61B17/12013 ,  A61B2017/00004 ,  A61B2017/00623 ,  A61B2017/0065 ,  A61B2017/00659 ,  A61B2017/00663 ,  A61B2017/00893 ,  A61B2017/0472 ,  A61B2017/0475 ,  A61B2017/0477

摘要： A solution is provided to release a tissue cinching loop within a body having a first thread having a first end and a second end, and a second thread having a first half having a first tip, a second half having a second tip, a bottom half having a link, and a top half, wherein the first end is inserted through the link. A first knot is formed around the first thread with the top half thereby forming a loop where the diameter of the loop decreases as the knot is pushed into the body and the first thread is pulled out of the body and where the loop is released within the body when the first end is pulled out of the body.

摘要翻译： 提供一种解决方案来释放具有第一螺纹的主体内的组织束紧环，所述第一螺纹具有第一端和第二端，第二螺纹具有第一半部，其具有第一末端，第二半部分具有第二末端，下半部 具有连接件和上半部分，其中第一端部通过连杆插入。 第一个结被形成在具有上半部分的第一个螺纹周围，从而形成一个环，其中环的直径随着结被推入体内而减小，并且第一个螺纹被拉出身体，并且在该位置内释放环 身体第一端被拉出身体时。

公开(公告)号：US07753872B2

公开(公告)日：2010-07-13

申请号：US10354517

申请日：2003-01-29

申请人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

发明人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

IPC分类号： A61M31/00

CPC分类号： A61B17/0057 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2090/064

摘要： A device, system and method for improving delivery of hemostatic material, in which the device includes a vent cap body capable of removably engaging a cannula. The vent cap has a passage extending through the vent cap body from the cannula to an exterior of the vent cap body where a restricter for restricting the flow of fluid from the cannula to the exterior. In one embodiment, the vent cap has a valve which has an opened and closed position. In the closed position, the valve is designed to provide a back pressure or resistance. When a certain force is applied against the valve, the valve moves from the closed position to the opened position, where a gas or fluid may pass through the vent cap. The vent cap is designed to help maintain the continuity of the hemostatic material during delivery of the material from the adaptor to the trial staging chamber.

摘要翻译： 一种用于改善止血材料递送的装置，系统和方法，其中所述装置包括能够可移除地接合插管的通气盖体。 通气盖具有从插管延伸穿过通气盖体的通道到通气盖体的外部，其中用于限制流体从套管流向外部的限制器。 在一个实施例中，通气盖具有具有打开和关闭位置的阀。 在关闭位置，阀被设计成提供背压或阻力。 当对阀门施加一定的力时，阀门从关闭位置移动到打开位置，气体或流体可以通过通气盖。 通气盖被设计成有助于在将材料从适配器递送到试验分级室时保持止血材料的连续性。

公开(公告)号：US20100049245A1

公开(公告)日：2010-02-25

申请号：US12606526

申请日：2009-10-27

申请人： Andrew H. Cragg ,  Mark Ashby

发明人： Andrew H. Cragg ,  Mark Ashby

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2090/062

摘要： A method of facilitating hemostasis of a blood vessel puncture. The method includes the steps of inserting a tubular device into a puncture in a blood vessel to establish access to the blood vessel, providing a vessel closure system around the tubular device, introducing a hemostatic material into a space between the tubular device and vessel closure system, and delivering the hemostatic material adjacent to the puncture to facilitate hemostasis of the puncture.

摘要翻译： 促进血管穿刺止血的方法。 该方法包括以下步骤：将管状装置插入到血管中的穿刺中以建立对血管的通路，在管状装置周围提供容器封闭系统，将止血材料引入管状装置和血管封闭系统之间的空间 并且将止血材料输送到穿刺附近以促进穿刺止血。

公开(公告)号：US07048710B1

公开(公告)日：2006-05-23

申请号：US09613439

申请日：2000-07-11

申请人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

发明人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

IPC分类号： A61F13/20

CPC分类号： A61B17/0057 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00654

摘要： A system for facilitating hemostasis of a puncture site in a blood vessel injects an absorbable sponge pledget in a hydrated state at an exterior of the blood vessel puncture to facilitate hemostasis. The system includes a tract dilator for locating the puncture, an introducer, and a plunger. The introducer includes a staging chamber for receiving the absorbent sponge pledget and a delivery chamber having a diameter smaller than a diameter of the staging chamber into which a hydrated pledget passes. The pledget is hydrated and compressed within the introducer and then ejected with the plunger to the delivery site to facilitate hemostasis of the blood vessel puncture. The system delivers the absorbable sponge pledget over a guidewire to ensure the proper positioning of the pledget over the puncture. The implanted absorbable sponge once delivered expands rapidly to fill the target site and is absorbed by the body over time.