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1.发明申请Tetrahydronaphthalene derivates, processes for preparing them and their use as antiinflammatory agents 失效四氢萘衍生物，其制备方法及其作为抗炎剂的用途公开(公告)号：US20070225290A1
公开(公告)日：2007-09-27
申请号：US11717782
申请日：2007-03-14
IPC分类号： A61K31/517 , A61K31/502 , A61K31/4704 , A61K31/366
CPC分类号： C07D215/227 , C07D209/34 , C07D215/38 , C07D215/60 , C07D217/24 , C07D231/56 , C07D237/32 , C07D239/74 , C07D265/02 , C07D311/76
摘要： The invention relates to multiply substituted tetrahydronaphthalene derivatives of the formula (Ia) to processes for preparing them and to their use as antiinflammatory agents.
摘要翻译： 本发明涉及式（Ia）的多取代四氢萘衍生物用于制备它们的方法及其作为抗炎剂的用途。
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2.发明申请Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs 审中-公开三环氨基醇，其合成方法和使用与抗炎药物相同公开(公告)号：US20060167025A1
公开(公告)日：2006-07-27
申请号：US11312655
申请日：2005-12-21
申请人： Markus Berger , Norbert Schmees , Heike Schaecke , Stefan Baurle , Hartmut Rehwinkel , Anne Mengel , Konrad Krolikiewicz , Danja Grossbach , David Voigtlaender
发明人： Markus Berger , Norbert Schmees , Heike Schaecke , Stefan Baurle , Hartmut Rehwinkel , Anne Mengel , Konrad Krolikiewicz , Danja Grossbach , David Voigtlaender
IPC分类号： A61K31/517 , A61K31/403 , A61K31/381 , A61K31/343
CPC分类号： C07D409/12 , C07D405/12
摘要： The invention relates to tricyclic amino alcohols of general formula (I) method for synthesis of same and use of same as anti-inflammatory agents.
摘要翻译： 本发明涉及通式（I）的合成方法的三环氨基醇及其与抗炎剂的用途。
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![5-[(3,3,3-Trifluoro-2-hydroxy-1-arylpropyl)amino]-1H-quinolin-2-ones, a process for their production and their use as anti-inflammatory agents](/abs-image/US/2014/03/25/US08680117B2/abs.jpg.150x150.jpg)
3.发明授权5-[(3,3,3-Trifluoro-2-hydroxy-1-arylpropyl)amino]-1H-quinolin-2-ones, a process for their production and their use as anti-inflammatory agents 有权5 - [（3,3,3-三氟-2-羟基-1-芳基丙基）氨基] -1H-喹啉-2-酮，其制备方法及其作为抗炎剂公开(公告)号：US08680117B2
公开(公告)日：2014-03-25
申请号：US13614161
申请日：2012-09-13
申请人： Markus Berger , Hartmut Rehwinkel , Thomas Zollner , Bkkehard May , Jorma Hassfeld , Heike Schacke
发明人： Markus Berger , Hartmut Rehwinkel , Thomas Zollner , Bkkehard May , Jorma Hassfeld , Heike Schacke
IPC分类号： A61K31/04
CPC分类号： C07D215/38 , C07C45/00 , C07C45/58 , C07C45/71 , C07C49/82 , C07C49/84 , C07D303/32 , C07D405/12 , C07C47/575 , C07C47/565
摘要： The present invention relates to compounds of formula I, processes for their production and their use as anti-inflammatory agents.
摘要翻译： 本发明涉及式I化合物，其制备方法及其作为抗炎剂的用途。
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![5-[(3,3,3-Trifluoro-2-hydroxy-1-arylpropyl)amino]-1H-quinolin-2-ones, A Process for Their Production and Their Use as Anti-inflammatory Agents](/abs-image/US/2009/05/28/US20090137564A1/abs.jpg.150x150.jpg)
4.发明申请5-[(3,3,3-Trifluoro-2-hydroxy-1-arylpropyl)amino]-1H-quinolin-2-ones, A Process for Their Production and Their Use as Anti-inflammatory Agents 有权5 - [（3,3,3-三氟-2-羟基-1-芳基丙基）氨基] -1H-喹啉-2-酮，其制备方法及其作为抗炎剂公开(公告)号：US20090137564A1
公开(公告)日：2009-05-28
申请号：US12275392
申请日：2008-11-21
申请人： Markus Berger , Hartmut Rehwinkel , Thomas Zollner , Ekkehard May , Jorna Hassfeld , Heike Schacke
发明人： Markus Berger , Hartmut Rehwinkel , Thomas Zollner , Ekkehard May , Jorna Hassfeld , Heike Schacke
IPC分类号： A61K31/551 , C07D215/227 , A61K31/4704 , C07D303/32
CPC分类号： C07D215/38 , C07C45/00 , C07C45/58 , C07C45/71 , C07C49/82 , C07C49/84 , C07D303/32 , C07D405/12 , C07C47/575 , C07C47/565
摘要： The present invention relates to compounds of formula I, processes for their production and their use as anti-inflammatory agents.
摘要翻译： 本发明涉及式I化合物，其制备方法及其作为抗炎剂的用途。
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5.发明申请BENZYL AMINES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS 有权苯甲酰胺，其生产工艺及其作为抗炎剂的用途公开(公告)号：US20080032986A1
公开(公告)日：2008-02-07
申请号：US11777411
申请日：2007-07-13
申请人： Markus Berger , Jan Dahmen , Hartmut Rehwinkel , Stefan Jaroch , Heike Schacke
发明人： Markus Berger , Jan Dahmen , Hartmut Rehwinkel , Stefan Jaroch , Heike Schacke
IPC分类号： A61K31/135 , A61K31/4164 , A61K31/47 , A61K31/502 , A61K31/517 , A61P29/00 , C07C215/28 , C07D215/38 , C07D233/84 , C07D237/30 , C07D239/74 , C07D301/00 , C07D401/12 , C07D405/12
CPC分类号： C07C215/16 , C07B2200/07 , C07C215/28 , C07C217/70 , C07C317/28 , C07D215/38 , C07D233/84 , C07D401/12 , C07D405/12 , C07D405/14
摘要： The present invention relates to the compounds of formula I, processes for their production and their use as anti-inflammatory agents.
摘要翻译： 本发明涉及式I化合物，其制备方法及其作为抗炎剂的用途。
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6.发明申请TETRAHYDRONAPHTHALENYLAMIDES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS 审中-公开四氢萘甲酰胺，其生产方法及其作为抗炎剂的用途公开(公告)号：US20080200519A1
公开(公告)日：2008-08-21
申请号：US12032067
申请日：2008-02-15
申请人： Markus BERGER , Hartmut Rehwinkel , Heike Schacke , Ekkehard May , Werner Skuballa , Hermann Kunzer
发明人： Markus BERGER , Hartmut Rehwinkel , Heike Schacke , Ekkehard May , Werner Skuballa , Hermann Kunzer
IPC分类号： A61K31/4439 , C07D231/38 , C07D401/04 , A61K31/4192 , A61P29/00 , C07D249/04 , A61K31/415
CPC分类号： C07D231/40 , C07D207/34 , C07D233/90 , C07D249/06 , C07D401/04
摘要： The present invention relates to the compounds of formula I, processes for their production and their use as anti-inflammatory agents.
摘要翻译： 本发明涉及式I化合物，其制备方法及其作为抗炎剂的用途。
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![5-[(3,3,3-trifluoro-2-hydroxy-1-arylpropyl)amino]-1H-quinolin-2-ones, a process for their production and their use as anti-inflammatory agents](/abs-image/US/2013/03/12/US08394958B2/abs.jpg.150x150.jpg)
7.发明授权5-[(3,3,3-trifluoro-2-hydroxy-1-arylpropyl)amino]-1H-quinolin-2-ones, a process for their production and their use as anti-inflammatory agents 有权5 - [（3,3,3-三氟-2-羟基-1-芳基丙基）氨基] -1H-喹啉-2-酮，其制备方法及其作为抗炎剂公开(公告)号：US08394958B2
公开(公告)日：2013-03-12
申请号：US12275392
申请日：2008-11-21
申请人： Markus Berger , Hartmut Rehwinkel , Thomas Zollner , Ekkehard May , Jorma Hassfeld , Heike Schacke
发明人： Markus Berger , Hartmut Rehwinkel , Thomas Zollner , Ekkehard May , Jorma Hassfeld , Heike Schacke
IPC分类号： C07D215/38
CPC分类号： C07D215/38 , C07C45/00 , C07C45/58 , C07C45/71 , C07C49/82 , C07C49/84 , C07D303/32 , C07D405/12 , C07C47/575 , C07C47/565
摘要： The present invention relates to compounds of formula I, processes for their production and their use as anti-inflammatory agents.
摘要翻译： 本发明涉及式I化合物，其制备方法及其作为抗炎剂的用途。
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公开(公告)号：US07109212B2
公开(公告)日：2006-09-19
申请号：US11059682
申请日：2005-02-17
申请人： Stefan Jaroch , Manfred Lehmann , Norbert Schmees , Markus Berger , Hartmut Rehwinkel , Konrad Krolikiewicz , Werner Skuballa , Heike Schaecke , Arndt. J. G. Schottelius
发明人： Stefan Jaroch , Manfred Lehmann , Norbert Schmees , Markus Berger , Hartmut Rehwinkel , Konrad Krolikiewicz , Werner Skuballa , Heike Schaecke , Arndt. J. G. Schottelius
IPC分类号： A61K31/47 , A61K31/472 , C07D217/24 , C07D217/00 , C07D215/38
CPC分类号： C07D405/12 , A61K31/47 , C07D215/40 , C07D217/24
摘要： The invention relates to quinoline and isoquinoline derivatives of general formula I and a process for their production, and their use as inflammation inhibitors.
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9.发明申请公开(公告)号：US20050209324A1
公开(公告)日：2005-09-22
申请号：US10961406
申请日：2004-10-12
申请人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号： A61K31/135 , A61K31/195 , A61K31/277
CPC分类号： C07D209/34 , C07D213/74 , C07D215/04 , C07D215/227 , C07D215/38 , C07D215/60 , C07D217/24 , C07D231/56 , C07D237/32 , C07D239/74 , C07D277/64 , C07D307/88 , C07D405/12 , C07D471/04
摘要： The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.
摘要翻译： 本发明涉及四氢萘衍生物，其制备方法及其作为抗炎剂的用途。
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10.发明申请Rearranged pentanols, a process for their production and their use as anti-inflammatory agents 失效重排戊醇，其生产过程及其作为抗炎剂的用途公开(公告)号：US20050131226A1
公开(公告)日：2005-06-16
申请号：US10960757
申请日：2004-10-08
申请人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号： A61P29/00 , C07D209/46 , C07D215/38 , C07D231/56 , C07D237/32 , C07D239/74 , C07D277/68 , C07D311/76 , C07D471/02 , C07D498/02
CPC分类号： C07D209/46 , C07D215/38 , C07D231/56 , C07D237/32 , C07D239/74 , C07D311/76
摘要： The invention relates to the compounds of formula I, a process for their production and their use as anti-inflammatory agents.
摘要翻译： 本发明涉及式I化合物，其制备方法及其作为抗炎剂的用途。
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