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公开(公告)号：US08388985B2
公开(公告)日：2013-03-05
申请号：US13422288
申请日：2012-03-16
申请人： Martin Leser , Laurent Sagalowicz , Martin Michel , Philippe Frossard , Corinne Appolonia-Nouzille
发明人： Martin Leser , Laurent Sagalowicz , Martin Michel , Philippe Frossard , Corinne Appolonia-Nouzille
CPC分类号： A23D7/0053 , A23D7/011 , B01F17/00
摘要： The present invention relates to the use of a lipidic phase comprising an oil and a lipophilic additive (LPA), which is suitable to make an oil-in-water emulsion by application of low energy or a manual operation. The lipidic phase contains a Lipophilic Additive (LPA) which forms self-assembly structures inside the emulsion oil droplets. The aqueous phase contains a hydrophilic emulsifier and the lipidic and aqueous phases are mixed without using classical high shearing devices or homogenisers.
摘要翻译： 本发明涉及包含油和亲脂性添加剂（LPA）的脂质相的使用，其适用于通过施加低能量或手动操作制备水包油乳液。 脂质相含有在乳液油滴内形成自组装结构的亲脂性添加剂（LPA）。 水相含有亲水乳化剂，并且不使用经典的高剪切装置或均化器混合脂质和水相。
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公开(公告)号：US20120177708A1
公开(公告)日：2012-07-12
申请号：US13422288
申请日：2012-03-16
申请人： Martin Leser , Laurent Sagalowicz , Martin Michel , Philippe Frossard , Corinne Appolonia-Nouzille
发明人： Martin Leser , Laurent Sagalowicz , Martin Michel , Philippe Frossard , Corinne Appolonia-Nouzille
IPC分类号： A61K8/06 , A23D7/04 , A61K9/107 , C08K5/101 , C09D191/00 , C09K8/28 , C09D189/00 , C09D105/00 , A23D7/005 , C11D3/60
CPC分类号： A23D7/0053 , A23D7/011 , B01F17/00
摘要： The present invention relates to the use of a lipidic phase comprising an oil and a lipophilic additive (LPA), which is suitable to make an oil-in-water emulsion by application of low energy or a manual operation. The lipidic phase contains a Lipophilic Additive (LPA) which forms self-assembly structures inside the emulsion oil droplets. The aqueous phase contains a hydrophilic emulsifier and the lipidic and aqueous phases are mixed without using classical high shearing devices or homogenisers.
摘要翻译： 本发明涉及包含油和亲脂性添加剂（LPA）的脂质相的使用，其适用于通过施加低能量或手动操作制备水包油乳液。 脂质相含有在乳液油滴内形成自组装结构的亲脂性添加剂（LPA）。 水相含有亲水乳化剂，并且不使用经典的高剪切装置或均化器混合脂质和水相。
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公开(公告)号：US20080311211A1
公开(公告)日：2008-12-18
申请号：US12094682
申请日：2006-11-22
申请人： Martin Leser , Laurent Sagalowicz , Martin Michel , Philippe Frossard , Corinne Appolonia-Nouzille
发明人： Martin Leser , Laurent Sagalowicz , Martin Michel , Philippe Frossard , Corinne Appolonia-Nouzille
CPC分类号： A23D7/0053 , A23D7/011 , B01F17/00
摘要： The present invention relates to the use of a lipidic phase comprising an oil and a lipophilic additive (LPA), which is suitable to make an oil-in-water emulsion by application of low energy or a manual operation. The lipidic phase contains a Lipophilic Additive (LPA) which forms self-assembly structures inside the emulsion oil droplets. The aqueous phase contains a hydrophilic emulsifier and the lipidic and aqueous phases are mixed without using classical high shearing devices or homogenisers.
摘要翻译： 本发明涉及包含油和亲脂性添加剂（LPA）的脂质相的使用，其适用于通过施加低能量或手动操作制备水包油乳液。 脂质相含有在乳液油滴内形成自组装结构的亲脂性添加剂（LPA）。 水相含有亲水乳化剂，并且不使用经典的高剪切装置或均化器混合脂质和水相。
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公开(公告)号：US20080299200A1
公开(公告)日：2008-12-04
申请号：US12094690
申请日：2006-11-22
申请人： Martin Leser , Laurent Sagalowicz , Martin Michel , Samuel Guillot , Otto Glatter , Matija Tomsic
发明人： Martin Leser , Laurent Sagalowicz , Martin Michel , Samuel Guillot , Otto Glatter , Matija Tomsic
CPC分类号： B01J13/0065 , B01F17/0028 , B01F17/0042 , B01F17/005 , B01F17/0057 , B01F17/0085
摘要： The invention concerns an oil-in-water emulsion wherein the oil droplets of a diameter in the range of 5 nm to hundreds of micrometers exhibit a nano-sized self-assembled structure with hydrophilic domains having a diameter size in the range of 0.5 to 200 nm, due to the presence of a lipophilic additive, and the oil-in-water emulsion contains a thickener or gelling agent in order to create new product consistencies and textures.
摘要翻译： 本发明涉及一种水包油乳液，其中直径在5nm至几百微米范围内的油滴显示出具有直径尺寸在0.5至200范围内的亲水区域的纳米尺寸自组装结构 nm，由于存在亲脂性添加剂，并且水包油乳液含有增稠剂或胶凝剂以产生新的产品一致性和纹理。
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公开(公告)号：US08158687B2
公开(公告)日：2012-04-17
申请号：US11569338
申请日：2005-05-18
申请人： Anan Yaghmur , Liliana De Campo , Laurent Sagalowicz , Martin Leser , Otto Glatter , Martin Michel , Heribert Johann Watzke
发明人： Anan Yaghmur , Liliana De Campo , Laurent Sagalowicz , Martin Leser , Otto Glatter , Martin Michel , Heribert Johann Watzke
CPC分类号： A23D7/0053 , A23D7/011
摘要： The present invention concerns an oil-in-water emulsion wherein the oil droplets of a diameter in the range of 5 nm to hundreds of micrometers exhibit a nano-sized structurization with hydrophilic domains with a diameter size in the range of 0.5 to 200 nm and being formed by a lipophilic additive.
摘要翻译： 本发明涉及一种水包油乳液，其中直径在5nm至几百微米范围内的油滴显示具有直径尺寸在0.5至200nm范围内的亲水区域的纳米尺寸结构化，以及 由亲脂性添加剂形成。
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公开(公告)号：US20080255247A1
公开(公告)日：2008-10-16
申请号：US12093560
申请日：2006-11-22
申请人： Laurent Sagalowicz , Martin Leser , Martin Michel , Heribert Johann Watzke , Simone Acquistapace , Raymond Bertholet , Birgit Holst , Fabien Robert
发明人： Laurent Sagalowicz , Martin Leser , Martin Michel , Heribert Johann Watzke , Simone Acquistapace , Raymond Bertholet , Birgit Holst , Fabien Robert
CPC分类号： B82Y5/00 , A23L27/80 , A23L33/11 , A23L33/12 , A23L33/15 , A23V2002/00 , A61K8/06 , A61K8/062 , A61K8/068 , A61K9/1075 , A61K9/113 , A61K9/1274 , A61K2800/21 , A61Q19/00 , A23V2200/222 , A23V2250/194 , A23V2250/21 , A23V2250/192
摘要： The present invention concerns an oil-in-water emulsion wherein the oil droplets of a diameter in the range of 5 nm to hundreds of micrometers exhibit a nano-sized self-assembled structurization with hydrophilic domains having a diameter size in the range of 0.5 to 200 nm, due to the presence of a lipophilic additive and the oil-in-water emulsion contains an active element being present in the range comprised between 0.00001 and 79% based on the total composition.
摘要翻译： 本发明涉及一种水包油乳液，其中直径在5nm至几百微米范围内的油滴显示出纳米尺寸的自组装结构，其中亲水区域的直径尺寸范围为0.5至 200nm，由于存在亲脂性添加剂，并且水包油乳液含有基于总组合物在0.00001至79％之间的范围内的活性元素。
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公开(公告)号：US08513311B2
公开(公告)日：2013-08-20
申请号：US12093560
申请日：2006-11-22
申请人： Laurent Sagalowicz , Martin Leser , Martin Michel , Heribert Johann Watzke , Simone Acquistapace , Raymond Bertholet , Birgit Holst , Fabien Robert
发明人： Laurent Sagalowicz , Martin Leser , Martin Michel , Heribert Johann Watzke , Simone Acquistapace , Raymond Bertholet , Birgit Holst , Fabien Robert
CPC分类号： B82Y5/00 , A23L27/80 , A23L33/11 , A23L33/12 , A23L33/15 , A23V2002/00 , A61K8/06 , A61K8/062 , A61K8/068 , A61K9/1075 , A61K9/113 , A61K9/1274 , A61K2800/21 , A61Q19/00 , A23V2200/222 , A23V2250/194 , A23V2250/21 , A23V2250/192
摘要： The present invention concerns an oil-in-water emulsion wherein the oil droplets of a diameter in the range of 5 nm to hundreds of micrometers exhibit a nano-sized self-assembled structurization with hydrophilic domains having a diameter size in the range of 0.5 to 200 nm, due to the presence of a lipophilic additive and the oil-in-water emulsion contains an active element being present in the range comprised between 0.00001 and 79% based on the total composition.
摘要翻译： 本发明涉及一种水包油乳液，其中直径在5nm至几百微米范围内的油滴显示出纳米尺寸的自组装结构，其中亲水区域的直径尺寸范围为0.5至 200nm，由于存在亲脂性添加剂，并且水包油乳液含有基于总组合物在0.00001至79％之间的范围内的活性元素。
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公开(公告)号：US20070213234A1
公开(公告)日：2007-09-13
申请号：US11569338
申请日：2005-05-18
申请人： Anan Yaghmur , Liliana De Campo , Laurent Sagalowicz , Martin Leser , Otto Glatter , Martin Michel , Heribert Watzke
发明人： Anan Yaghmur , Liliana De Campo , Laurent Sagalowicz , Martin Leser , Otto Glatter , Martin Michel , Heribert Watzke
IPC分类号： C10M169/04
CPC分类号： A23D7/0053 , A23D7/011
摘要： The present invention concerns an oil-in-water emulsion wherein the oil droplets of a diameter in the range of 5 nm to hundreds of micrometers exhibit a nano-sized structurisation with hydrophilic domains with a diameter size in the range of 0.5 to 200 nm and being formed by a lipophilic additive.
摘要翻译： 本发明涉及一种水包油乳液，其中直径在5nm至几百微米范围内的油滴表现出具有直径尺寸在0.5至200nm范围内的亲水区域的纳米尺寸结构化，以及 由亲脂性添加剂形成。
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9.发明申请OIL-IN-WATER EMULSION AND ITS USE FOR THE DELAYED RELEASE OF ACTIVE ELEMENTS 审中-公开水中水乳剂及其用于延迟释放活性元素的用途公开(公告)号：US20100172875A1
公开(公告)日：2010-07-08
申请号：US12602339
申请日：2008-05-30
IPC分类号： A61K35/74 , A61K38/02 , A61K8/64 , A61K31/70 , A61K8/60 , A61K31/715 , A61K8/73 , A61K8/99 , A61K38/43 , A61K8/66 , A61K31/047 , A61K8/34 , A61K31/355 , A61K8/67 , A61K31/122 , A61K8/35 , A61K36/55 , A61K8/97 , A61K36/534 , A61K35/60 , A61K8/98 , A61K31/202 , A61K8/36 , A61K31/375 , A61K31/714 , A61K31/522 , A61K8/49 , A61P3/02 , A61P39/06 , A23L1/22 , A61K8/04
CPC分类号： A61K9/107 , A23D7/0053 , A23D7/011 , A23L29/10
摘要： The present invention concerns the use of an oil-in-water emulsion where the interior of oil droplets exhibit interfaces, between lipophilic domains and hydrophilic or amphiphilic domains, due to the presence of a lipophilic additive solubilized inside the oil droplets and which is used for delayed release of active elements such that the release of at least one active element, which has a octanol/water partitioning coefficient logP higher than −1, corresponds to a higher Tmax than the Tmax obtained for the simple reference oil-in-water emulsion where no lipophilic additive is used.
摘要翻译： 本发明涉及使用水包油乳液，其中由于存在可溶于油滴内部的亲脂性添加剂，油包水乳液的内部在亲油性域与亲水性或两亲性结构域之间呈现界面，并且用于 活性元素的延迟释放使得具有高于-1的辛醇/水分配系数logP的至少一种活性元素的释放对应于比简单参考水包油乳液获得的Tmax更高的Tmax，其中 不使用亲脂性添加剂。
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10.发明授权公开(公告)号：US08920862B2
公开(公告)日：2014-12-30
申请号：US12737247
申请日：2009-06-22
申请人： Laurent Sagalowicz , Tomas Davidek , Florian Viton , Haiqing Yu , Martin Leser
发明人： Laurent Sagalowicz , Tomas Davidek , Florian Viton , Haiqing Yu , Martin Leser
IPC分类号： A23L1/22 , A23L2/56 , A23D7/00 , A23D9/00 , A23B7/157 , A23L1/27 , C12C5/04 , C12C3/08 , C12C3/12 , C12C7/00 , C12C7/14 , A23D7/01 , A23D7/005 , A23K1/16 , A23K1/18 , A23L1/227
CPC分类号： A23D7/011 , A23D7/0053 , A23K20/10 , A23K20/158 , A23K50/40 , A23L27/215
摘要： The invention provides methods for making Maillard flavor compositions in a structured lipid phase using Maillard reactants, e.g., reducing sugars and amino groups. The structured lipid phase comprises from about 0.3% to about 95% aqueous solvent and from about 5% to about 99.7% lipid plus emulsifier. The compositions are useful for enhancing the palatability of foods, dietary supplements, medicaments, and the like.
摘要翻译： 本发明提供了使用美拉德反应物制备美拉德风味组合物在结构化脂质相中的方法，例如还原糖和氨基。 结构化脂质相包含约0.3％至约95％的水性溶剂和约5％至约99.7％的脂质加乳化剂。 该组合物可用于增强食物，膳食补充剂，药物等的适口性。
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