公开(公告)号：US08349857B2

公开(公告)日：2013-01-08

申请号：US13359326

申请日：2012-01-26

申请人： Masaharu Kume ,  Kenji Matsuo ,  Naoki Omori ,  Masami Takayama ,  Aiko Omori ,  Takeshi Endo

发明人： Masaharu Kume ,  Kenji Matsuo ,  Naoki Omori ,  Masami Takayama ,  Aiko Omori ,  Takeshi Endo

IPC分类号： A01N43/54 ,  A61K31/517 ,  C07D239/72

CPC分类号： C07D239/94 ,  C07D401/12 ,  C07D401/14 ,  C07D405/06 ,  C07D405/12 ,  C07D407/12 ,  C07D417/12

摘要： A compound which inhibits both of EGF receptor tyrosine kinase and HER2 tyrosine kinase is provided.A compound represented by the general formula (I): wherein RX is a group represented by the formula: wherein R1 is a hydrogen atom, optionally substituted alkyl, etc.; Z is —O—, —N(R10)—, etc.; R10 is a hydrogen atom, alkyl, etc.; R2 is a hydrogen atom, optionally substituted alkyl, etc.; R18 is a hydrogen atom, optionally substituted alkyl, etc.; R19 is optionally substituted alkyl, etc.; W1 is an optionally substituted non-aromatic nitrogen-containing group; R17 is a hydrogen atom, optionally substituted alkyl, etc.; R3 and R4 are independently a hydrogen atom, optionally substituted alkyl, etc.; X is —O—, —S—, or —N(R12)—, etc.; R12 is a hydrogen atom, alkyl, etc.; and A is phenyl optionally having a substituent, etc., its pharmaceutically acceptable salt, or a solvate thereof.

摘要翻译： 提供抑制EGF受体酪氨酸激酶和HER2酪氨酸激酶两者的化合物。 由通式（I）表示的化合物：其中RX是由下式表示的基团：其中R1是氢原子，任选取代的烷基等; Z是-O - ， - N（R 10） - 等; R10是氢原子，烷基等; R2是氢原子，任选取代的烷基等; R18是氢原子，任意取代的烷基等; R19是任选取代的烷基等; W1是任选取代的非芳族含氮基团; R 17是氢原子，任选取代的烷基等; R3和R4独立地是氢原子，任选取代的烷基等; X是-O-，-S-或-N（R 12） - 等; R12是氢原子，烷基等; 和A是任选具有取代基的苯基等，其药学上可接受的盐或其溶剂合物。

公开(公告)号：US08813869B2

公开(公告)日：2014-08-26

申请号：US12052503

申请日：2008-03-20

申请人： Nicholas Bennett ,  Jakob Brandt Utne Haldorsen ,  Hiroaki Yamamoto ,  Nobuyasu Hirabayasbi ,  Takeshi Endo ,  Richard Timothy Coates

发明人： Nicholas Bennett ,  Jakob Brandt Utne Haldorsen ,  Hiroaki Yamamoto ,  Nobuyasu Hirabayasbi ,  Takeshi Endo ,  Richard Timothy Coates

IPC分类号： E21B44/00 ,  G01V1/40 ,  E21B47/022 ,  G01V1/50 ,  E21B7/04

CPC分类号： E21B7/04 ,  E21B47/02208 ,  G01V1/50

摘要： Methods and related systems are described for measuring and analyzing refracted acoustic energy. A plurality of receivers mounted are on a downhole tool, and are arranged and adapted to receive refracted acoustic energy from a downhole formation. Measurements of refracted acoustic energy is analyzed such that information relating to an azimuthal direction relative to the downhole tool of an interface within the downhole formation can be estimated. The receivers can be mounted on a drill collar as part of a LWD tool and steering of the drilling trajectory can be based in part on the estimated formation information.

摘要翻译： 描述了用于测量和分析折射声能的方法和相关系统。 安装的多个接收器位于井下工具上，并被布置和适于从井下地层接收折射的声能。 分析折射声能的测量，从而可以估计与井下地层内的界面相对于井下工具的方位角方向有关的信息。 接收器可以安装在钻铤上作为LWD工具的一部分，并且钻井轨迹的转向可以部分地基于估计的地层信息。

公开(公告)号：US08748650B2

公开(公告)日：2014-06-10

申请号：US13060391

申请日：2009-08-26

申请人： Takeshi Endo ,  Koichi Koga ,  Atsushi Sudo

发明人： Takeshi Endo ,  Koichi Koga ,  Atsushi Sudo

IPC分类号： C07C205/00

CPC分类号： C07D263/44 ,  C07C271/54 ,  C07C323/59

摘要： A method for production of an N-carboxy amino acid anhydride with efficiency is provided. The method for production of an N-carboxy amino acid anhydride includes a step of reaction of an amino acid organic salt compound with a carbonic acid diester.

摘要翻译： 提供了生产N-羧基氨基酸酐的方法。 制备N-羧基氨基酸酐的方法包括氨基酸有机盐化合物与碳酸二酯反应的步骤。

公开(公告)号：US08748563B2

公开(公告)日：2014-06-10

申请号：US13453451

申请日：2012-04-23

申请人： Hiroshi Yamashita ,  Atsushi Sudo ,  Takeshi Endo ,  Andreas Taden ,  Rainer Schoenfeld ,  Iris Christa Huver

发明人： Hiroshi Yamashita ,  Atsushi Sudo ,  Takeshi Endo ,  Andreas Taden ,  Rainer Schoenfeld ,  Thomas Huver

IPC分类号： C08G59/68 ,  B32B5/12 ,  C08F283/00 ,  C08L63/00

CPC分类号： C08G59/687 ,  C08G59/4014 ,  C08G73/06 ,  C08K5/42 ,  C08L63/00 ,  Y10T428/24132 ,  Y10T428/249921

摘要： The present invention relates to a curable composition, comprising at least one benzoxazine compound, and at least one sulfonic acid ester having a cyclic structure. In particular, the invention relates to the use of at least one sulfonic acid having a cyclic structure as a heat-activatable catalyst for curable composition, comprising at least one benzoxazine compound.

摘要翻译： 本发明涉及包含至少一种苯并恶嗪化合物和至少一种具有环状结构的磺酸酯的可固化组合物。 特别地，本发明涉及至少一种具有环状结构的磺酸作为可固化组合物的可热活化催化剂的用途，其包含至少一种苯并恶嗪化合物。

公开(公告)号：US20140107350A1

公开(公告)日：2014-04-17

申请号：US14112795

申请日：2012-04-20

申请人： Akitake Nakamura ,  Takeshi Endo

发明人： Akitake Nakamura ,  Takeshi Endo

IPC分类号： C07D331/02

CPC分类号： C07D331/02

摘要： Provided is a method for producing an episulfide compound, the method including a step of thiating epoxy groups of (B) an epoxy compound by a reaction with (C) a thiating agent in the presence of (A) a polyhydric hydroxyl compound having two or more hydroxyl groups.

摘要翻译： 提供了一种环硫化合物的制备方法，该方法包括在（A）具有两个或多个羟基化合物的多羟基化合物的存在下，通过与（C）硫化剂的反应，将（B）环氧化合物的环氧基 更多的羟基。

公开(公告)号：US20120147702A1

公开(公告)日：2012-06-14

申请号：US13310780

申请日：2011-12-04

申请人： Henri-Pierre Valero ,  Shinichi Sunaga ,  Takeshi Endo

发明人： Henri-Pierre Valero ,  Shinichi Sunaga ,  Takeshi Endo

IPC分类号： G01V1/40

CPC分类号： G01V1/48 ,  G01V1/44 ,  G01V2210/23

摘要： Methods and apparatus to filter acoustic waveforms in downhole environments are described. An example method involves receiving acoustic waveform data representing acoustic signals traversing at least a portion of a borehole adjacent a subterranean formation and performing a direct transform operation on the acoustic waveform data to generate wavelet map data. The wavelet map data comprises a time-frequency representation of the acoustic waveform data. The example method also involves identifying a waveform of interest via the wavelet map data, extracting data associated with the waveform of interest from the wavelet map data, generating filtered wavelet map data based on the extracted data, and performing an inverse transform operation on the filtered wavelet map data to generate filtered acoustic waveform data

摘要翻译： 描述了在井下环境中滤波声波的方法和装置。 示例性方法包括接收表示穿过邻近地层的钻孔的至少一部分的声信号的声波形数据，并且对声波形数据执行直接变换操作以产生小波图数据。 小波图数据包括声波形数据的时间 - 频率表示。 该示例方法还涉及通过小波变换图数据识别感兴趣的波形，从小波变换数据中提取与感兴趣波形相关联的数据，基于所提取的数据产生滤波后的小波变换数据，并对经滤波的 小波图数据生成滤波后的声波形数据

公开(公告)号：US20120059137A1

公开(公告)日：2012-03-08

申请号：US13319962

申请日：2010-05-10

申请人： Riina Kambara ,  Hideharu Mori ,  Takeshi Endo ,  Shigeaki Yonemori

发明人： Riina Kambara ,  Hideharu Mori ,  Takeshi Endo ,  Shigeaki Yonemori

IPC分类号： C08F12/18

CPC分类号： C08F12/18 ,  C08F112/14 ,  C08F2438/03

摘要： Provided is a monodisperse polymer of chloromethylstyrene as a bifunctional compound. Chloromethylstyrene is purified to a purity of at least 99% and polymerized preferably using a RAFT reagent.

摘要翻译： 提供氯甲基苯乙烯作为双官能化合物的单分散聚合物。 将氯甲基苯乙烯纯化至至少99％的纯度，并优选使用RAFT试剂进行聚合。

公开(公告)号：US08054326B2

公开(公告)日：2011-11-08

申请号：US12477961

申请日：2009-06-04

申请人： Takeshi Endo ,  Takahiro Kojima ,  Kazutoshi Takahashi

发明人： Takeshi Endo ,  Takahiro Kojima ,  Kazutoshi Takahashi

IPC分类号： B41J2/44

CPC分类号： G03G15/04072 ,  G03G15/0435

摘要： In a laser exposure device according to the present invention, a positioning pin, which is formed in a lens holder supporting a lens system, is inserted through an elongated hole for restriction of a board holder supporting a laser diode. An eccentric cam is inserted into an elongated hole for rotation movement formed in a board holder and a circular hole for rotation movement which is formed in the lens holder and which faces the elongated hole for rotation movement. An eccentric cam is inserted into an elongated hole for slide movement formed in the board holder and a circular hole for slide movement which is formed in the lens holder and which faces the elongated hole for slide movement. The eccentric cams are rotated to relatively move the board holder and lens holder with respect to each other to thereby establish alignment between the optical axes of the laser diode and lens system. In a state where the eccentric cams are fitted into the elongated holes, the board holder and lens holder are fixed to each other by screws.

摘要翻译： 在根据本发明的激光曝光装置中，形成在支撑透镜系统的透镜支架中的定位销被插入通过长孔以限制支撑激光二极管的板支架。 偏心凸轮被插入到用于旋转运动的长孔中，形成在板保持器中的旋转运动和用于旋转运动的圆形孔，其形成在透镜保持器中并面向用于旋转运动的细长孔。 偏心凸轮被插入到用于滑动运动的细长孔中，形成在板保持器中，并且用于滑动运动的圆形孔形成在透镜保持器中并面对用于滑动运动的长孔。 偏心凸轮旋转以相对于彼此相对地移动板保持器和透镜保持器，从而在激光二极管和透镜系统的光轴之间建立对准。 在将偏心凸轮装配到细长孔中的状态下，通过螺钉将板保持器和透镜保持器彼此固定。

公开(公告)号：US07740734B2

公开(公告)日：2010-06-22

申请号：US12275772

申请日：2008-11-21

申请人： Atsushi Sudo ,  Akane Suzuki ,  Takeshi Endo

发明人： Atsushi Sudo ,  Akane Suzuki ,  Takeshi Endo

IPC分类号： C09J163/00 ,  B05D3/02 ,  B05D3/06 ,  C08L63/00 ,  B32B27/38

CPC分类号： C08G59/68 ,  C08G59/42

摘要： The present invention relates to compositions comprising an epoxy resin; a reagent selected from the group of cationic compounds or compounds which are capable to form cationic compounds or mixtures of those; at least one compound with two aromatic rings and at least one central cyclic oxygen bridged ring and the use of such compositions in adhesives, sealants and coatings.

摘要翻译： 本发明涉及包含环氧树脂的组合物; 选自阳离子化合物或能够形成阳离子化合物或其混合物的化合物的试剂; 至少一种具有两个芳环和至少一个中心环氧桥环的化合物，以及在粘合剂，密封剂和涂料中使用这些组合物。

公开(公告)号：US20090114969A1

公开(公告)日：2009-05-07

申请号：US12289624

申请日：2008-10-30

申请人： Naohiro Suzuki ,  Yuuichi Takeuchi ,  Takeshi Endo ,  Eiichi Okuno ,  Toshimasa Yamamoto

发明人： Naohiro Suzuki ,  Yuuichi Takeuchi ,  Takeshi Endo ,  Eiichi Okuno ,  Toshimasa Yamamoto

IPC分类号： H01L29/94 ,  H01L21/04 ,  H01L29/68

CPC分类号： H01L29/7813 ,  H01L29/045 ,  H01L29/0619 ,  H01L29/0623 ,  H01L29/0634 ,  H01L29/0847 ,  H01L29/1095 ,  H01L29/1608 ,  H01L29/47 ,  H01L29/66068 ,  H01L29/7391 ,  H01L29/7397 ,  H01L29/7828

摘要： An SiC semiconductor device and a related manufacturing method are disclosed having a structure provided with a p+-type deep layer formed in a depth equal to or greater than that of a trench to cause a depletion layer between at a PN junction between the p+-type deep layer and an n−-type drift layer to extend into the n−-type drift layer in a remarkable length, making it difficult for a high voltage, resulting from an adverse affect arising from a drain voltage, to enter a gate oxide film. This results in a capability of minimizing an electric field concentration in the gate oxide film, i.e., an electric field concentration occurring at the gate oxide film at a bottom wall of the trench.

摘要翻译： 公开了一种SiC半导体器件和相关制造方法，其具有设置有等于或大于沟槽深度形成的p +型深层的结构，以在p +型之间的PN结处引起耗尽层 深层和n型漂移层以非常长的长度延伸到n型漂移层中，使得由于漏极电压引起的不利影响导致的高电压难以进入栅极氧化膜 。 这导致使栅极氧化膜中的电场浓度最小化的能力，即在沟槽的底壁处的栅极氧化膜处发生的电场浓度。