TWO-COMPONENT TISSUE ADHESIVE AND METHOD FOR PRODUCING SAME
    3.
    发明申请
    TWO-COMPONENT TISSUE ADHESIVE AND METHOD FOR PRODUCING SAME 有权
    双组分粘合剂及其生产方法

    公开(公告)号:US20130220174A1

    公开(公告)日:2013-08-29

    申请号:US13877880

    申请日:2011-10-04

    IPC分类号: C09J189/00

    CPC分类号: C09J189/00 A61L24/104

    摘要: The present invention addresses the problem of providing: a two-component tissue adhesive having high adhesive strength and high biocompatibility; and a method for producing the two-component tissue adhesive. The present invention involves a two-component tissue adhesive comprising hydrophobically-modified gelatin as a first agent and a cross-linking reagent as a second agent. The hydrophobically-modified gelatin is provided with an amino group and a hydrophobic group on the side chain thereof, and the cross-linking reagent has two or more active ester groups or anhydrides within a single molecule.

    摘要翻译: 本发明解决了提供:具有高粘合强度和高生物相容性的双组分组织粘合剂的问题; 以及双组分组织粘合剂的制造方法。 本发明涉及包含疏水改性明胶作为第一试剂的双组分组织粘合剂和作为第二试剂的交联剂。 疏水改性的明胶在其侧链上具有氨基和疏水性基团,交联剂在单分子内具有两个以上的活性酯基或酸酐。

    Two-component tissue adhesive and method for producing same
    4.
    发明授权
    Two-component tissue adhesive and method for producing same 有权
    双组分组织粘合剂及其制备方法

    公开(公告)号:US09499728B2

    公开(公告)日:2016-11-22

    申请号:US13877880

    申请日:2011-10-04

    CPC分类号: C09J189/00 A61L24/104

    摘要: The present invention addresses the problem of providing: a two-component tissue adhesive having high adhesive strength and high biocompatibility; and a method for producing the two-component tissue adhesive. The present invention involves a two-component tissue adhesive comprising hydrophobically-modified gelatin as a first agent and a cross-linking reagent as a second agent. The hydrophobically-modified gelatin is provided with an amino group and a hydrophobic group on the side chain thereof, and the cross-linking reagent has two or more active ester groups or anhydrides within a single molecule.

    摘要翻译: 本发明解决了提供:具有高粘合强度和高生物相容性的双组分组织粘合剂的问题; 以及双组分组织粘合剂的制造方法。 本发明涉及包含疏水改性明胶作为第一试剂的双组分组织粘合剂和作为第二试剂的交联剂。 疏水改性的明胶在其侧链上具有氨基和疏水性基团,交联剂在单分子内具有两个以上的活性酯基或酸酐。