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公开(公告)号：US07935673B2
公开(公告)日：2011-05-03
申请号：US11722211
申请日：2005-12-12
CPC分类号： A61K8/97 , A23L33/105 , A61K8/602 , A61K36/736 , A61K2800/522 , A61K2800/782 , A61Q19/00 , A61Q19/02 , C07H17/06
摘要： It is an objective of the present invention to provide a polyphenol glycoside isolated from acerola, which has a binding mode that has not been conventionally known, and to provide the use of the same.The present invention relates to a compound represented by formula (I): and an antioxidant, a glucosidase inhibitor, a food, a cosmetic, and a skin preparation for external use, each of which comprises such compound.
摘要翻译： 本发明的目的是提供一种从痤疮中分离出的多酚糖苷，其具有尚未公知的结合模式，并提供其使用。 本发明涉及由式（I）表示的化合物：抗氧化剂，葡糖苷酶抑制剂，食品，化妆品和外用皮肤制剂，每种都包含这种化合物。
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公开(公告)号：US20130309187A1
公开(公告)日：2013-11-21
申请号：US13980475
申请日：2011-01-20
摘要： This invention provides a skin-whitening agent, a tyrosinase activity inhibitor, and melanin production inhibitor comprising, as an active ingredient, a compound exhibiting excellent solubility in various solvents. Such skin-whitening agent, tyrosinase activity inhibitor, and melanin production inhibitor comprise 3-hydroxy-2-pyrone.
摘要翻译： 本发明提供一种皮肤增白剂，酪氨酸酶活性抑制剂和黑色素产生抑制剂，其包含在各种溶剂中表现出优异溶解性的化合物作为活性成分。 这种皮肤增白剂，酪氨酸酶活性抑制剂和黑色素产生抑制剂包含3-羟基-2-吡喃酮。
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公开(公告)号：US20080267894A1
公开(公告)日：2008-10-30
申请号：US11884880
申请日：2006-02-28
CPC分类号： C08L5/06 , A23L29/231 , A61K8/602 , A61K8/73 , A61K8/97 , A61K2800/522 , A61Q19/02 , C08B37/0045 , C12P19/14 , C12P19/445
摘要： The present invention relates to a pectin derived from an acerola fruit or a hydrolysate thereof, comprising a complex formed of Aceronidin, which is a novel polyphenol compound. The pectin of the present invention can be used as an active ingredient of an antioxidant or a skin-whitening agent.
摘要翻译： 本发明涉及一种来源于槭树果实或其水解产物的果胶，其中含有由新戊酸化合物（Aceronidin）形成的络合物。 本发明的果胶可以用作抗氧化剂或皮肤增白剂的活性成分。
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公开(公告)号：US20100029918A1
公开(公告)日：2010-02-04
申请号：US11722211
申请日：2005-12-12
IPC分类号： C07H17/04
CPC分类号： A61K8/97 , A23L33/105 , A61K8/602 , A61K36/736 , A61K2800/522 , A61K2800/782 , A61Q19/00 , A61Q19/02 , C07H17/06
摘要： It is an objective of the present invention to provide a polyphenol glycoside isolated from acerola, which has a binding mode that has not been conventionally known, and to provide the use of the same.The present invention relates to a compound represented by formula (I): and an antioxidant, a glucosidase inhibitor, a food, a cosmetic, and a skin preparation for external use, each of which comprises such compound.
摘要翻译： 本发明的目的是提供一种从痤疮中分离出的多酚糖苷，其具有尚未公知的结合模式，并提供其使用。 本发明涉及由式（I）表示的化合物：抗氧化剂，葡糖苷酶抑制剂，食品，化妆品和外用皮肤制剂，每种都包含这种化合物。
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5.发明申请PROANTHOCYANIDIN OF CASHEW APPLE, COMPOSITION CONTAINING PROANTHOCYANIDIN, AND APPLICATION THEREOF 有权CASHEW苹果的PROANTHOCYANIDIN，含有蒽醌的组合物及其应用公开(公告)号：US20110263698A1
公开(公告)日：2011-10-27
申请号：US13142238
申请日：2009-06-25
申请人： Kenichi Nagamine
发明人： Kenichi Nagamine
IPC分类号： A61K31/353 , C12N1/36 , A61P31/04 , C12N5/071 , C07D409/14 , A61P17/10
CPC分类号： C12N9/99 , A23L33/105 , A23L33/195 , A23V2002/00 , A61K31/353 , A61K36/22 , C07D311/62 , A23V2250/21166 , A23V2250/21 , A23V2250/5086
摘要： This invention provides useful applications of cashew apple. This invention also provides a naturally occurring active ingredient having useful activities, such as alpha-amylase inhibitory activity, lipase inhibitory activity, and antibacterial activity against Propionibacterium acnes. The invention also provides a composition containing cashew apple-derived proanthocyanidin having excellent alpha-amylase inhibitory activity, lipase inhibitory activity, and antibacterial activity against Propionibacterium acnes, which is prepared by allowing a plant fiber-degrading enzyme (e.g., pectinase) to react with a cashew apple and concentrating the resultant with the use of an ultrafiltration membrane. Further, the invention provides a proanthocyanidin compound having a novel structure.
摘要翻译： 本发明提供腰果苹果的有用应用。 本发明还提供具有有用活性的天然存在的活性成分，例如α-淀粉酶抑制活性，脂肪酶抑制活性和对痤疮丙酸杆菌的抗菌活性。 本发明还提供一种含有腰果苹果衍生的原花青素的组合物，其具有优异的α-淀粉酶抑制活性，脂肪酶抑制活性和对痤疮丙酸杆菌的抗菌活性，其通过使植物纤维降解酶（例如果胶酶）与 腰果苹果，并使用超滤膜浓缩所得物。 此外，本发明提供具有新颖结构的原花青素化合物。
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公开(公告)号：US07090872B2
公开(公告)日：2006-08-15
申请号：US10535382
申请日：2003-11-21
申请人： Kenichi Nagamine , Miki Hayashi , Kaori Yamasaki
发明人： Kenichi Nagamine , Miki Hayashi , Kaori Yamasaki
CPC分类号： C09K15/34 , A23L33/105 , A23V2002/00 , A61K8/97 , A61K2800/522 , A61Q19/00 , A61Q19/08 , A23V2200/02 , A23V2250/21
摘要： The invention relates to antioxidants that make effective use of acerola seeds, which have conventionally been discarded, that have high safety and excellent antioxidative effect in skin preparations for external use, cosmetics, and food, and that contain acerola seed extract as an active component. The invention also relates to skin preparations for external use, cosmetics, and food containing the antioxidant.
摘要翻译： 本发明涉及有效利用通常被丢弃的具有高安全性和优异抗氧化作用的皮肤外用的皮肤制剂，化妆品和食品的抗氧化剂，并且含有槭树种子提取物作为活性成分的抗氧化剂。 本发明还涉及外用皮肤制剂，化妆品和含有抗氧化剂的食品。
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7.发明申请Nerve Growth Factor Production Inhibitor and External Preparation for the Skin, Cosmetic, Quasi Drug, Preventive and Remedy for Atopic Dermatitis Containing the Nerve Growth Factor Production Inhibitor 审中-公开神经生长因子生产抑制剂和外用制剂，用于皮肤，化妆品，准药物，预防和补救含有神经生长因子生产抑制剂的特应性皮炎公开(公告)号：US20070286915A1
公开(公告)日：2007-12-13
申请号：US11665172
申请日：2005-10-14
IPC分类号： A61K36/185 , A61K131/00 , A61P17/00
CPC分类号： A61K36/736
摘要： It is an object of the present invention to provide a nerve growth factor production inhibitor having a function to inhibit the production of the nerve growth factor deeply involved with the extension of C fiber to epidermis, as well as a high safety, and an external preparation for the skin, a cosmetic, a quasi drug, a preventive and remedy for itching and a remedy for atopic dermatitis containing the nerve growth factor production inhibitor. The nerve growth factor production inhibitor is characterized in that an acerola seed extract is combined.
摘要翻译： 本发明的一个目的是提供一种神经生长因子产生抑制剂，其具有抑制C纤维延伸到表皮的神经生长因子生成的功能以及高安全性和外用制剂 用于皮肤，化妆品，准药物，瘙痒的预防和治疗以及含有神经生长因子产生抑制剂的特应性皮炎的补救措施。 神经生长因子产生抑制剂的特征在于将槭树种子提取物合并。
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公开(公告)号：US20060104927A1
公开(公告)日：2006-05-18
申请号：US10543801
申请日：2003-12-24
申请人： Kenichi Nagamine , Miki Hayashi , Kaori Yamasaki
发明人： Kenichi Nagamine , Miki Hayashi , Kaori Yamasaki
CPC分类号： A61K8/602 , A23L33/105 , A61K2800/522 , A61Q19/02 , C07H15/203
摘要： The compound of the present invention is a component originated from a natural material, camu camu (Myrciaria dubia), has strong antioxidative activity and stable whitening effect, and is represented by the formula (1). The antioxidant, whitening agent, skin preparation for external use, cosmetics, and food of the present invention are characterized by the inclusion of the compound represented by the formula (1).
摘要翻译： 本发明的化合物是天然物质（Myrciaria dubia）的成分，具有强的抗氧化活性和稳定的美白效果，由式（1）表示。 本发明的抗氧化剂，增白剂，外用皮肤制剂，化妆品，食品的特征在于含有式（1）表示的化合物。
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9.发明授权Proanthocyanidin of cashew apple, composition containing proanthocyanidin, and application thereof 有权腰果苹果花青素，含有原花色素的组合物及其应用公开(公告)号：US08575368B2
公开(公告)日：2013-11-05
申请号：US13142238
申请日：2009-06-25
申请人： Kenichi Nagamine
发明人： Kenichi Nagamine
IPC分类号： C07D311/76 , A61K31/353
CPC分类号： C12N9/99 , A23L33/105 , A23L33/195 , A23V2002/00 , A61K31/353 , A61K36/22 , C07D311/62 , A23V2250/21166 , A23V2250/21 , A23V2250/5086
摘要： This invention provides useful applications of cashew apple. This invention also provides a naturally occurring active ingredient having useful activities, such as alpha-amylase inhibitory activity, lipase inhibitory activity, and antibacterial activity against Propionibacterium acnes. The invention also provides a composition containing cashew apple-derived proanthocyanidin having excellent alpha-amylase inhibitory activity, lipase inhibitory activity, and antibacterial activity against Propionibacterium acnes, which is prepared by allowing a plant fiber-degrading enzyme (e.g., pectinase) to react with a cashew apple and concentrating the resultant with the use of an ultrafiltration membrane. Further, the invention provides a proanthocyanidin compound having a novel structure.
摘要翻译： 本发明提供腰果苹果的有用应用。 本发明还提供具有有用活性的天然存在的活性成分，例如α-淀粉酶抑制活性，脂肪酶抑制活性和对痤疮丙酸杆菌的抗菌活性。 本发明还提供一种含有腰果苹果衍生的原花青素的组合物，其具有优异的α-淀粉酶抑制活性，脂肪酶抑制活性和对痤疮丙酸杆菌的抗菌活性，其通过使植物纤维降解酶（例如果胶酶）与 腰果苹果，并使用超滤膜浓缩所得物。 此外，本发明提供具有新颖结构的原花青素化合物。
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公开(公告)号：US07192617B2
公开(公告)日：2007-03-20
申请号：US10537958
申请日：2003-12-08
申请人： Kenichi Nagamine , Miki Hayashi , Kaori Yamasaki
发明人： Kenichi Nagamine , Miki Hayashi , Kaori Yamasaki
IPC分类号： A61K36/00
摘要： The invention relates to a whitening agent that makes effective use of camu camu seeds, which have conventionally been discarded, and that has high safety and whitening effect useful in cosmetics and the like, as well as skin preparations for external use and cosmetics containing the whitening agent. The whitening agent of the present invention contains camu camu seed extract as an active component, and the skin preparations for external use and cosmetics of the present invention contain the whitening agent.
摘要翻译： 本发明涉及一种美白剂，其有效利用通常被丢弃的苦瓜种子，并且具有用于化妆品等的高安全性和增白效果，以及用于外用皮肤制剂和含有美白的化妆品 代理商 本发明的增白剂含有作为活性成分的苦瓜种子提取物，本发明的皮肤外用剂和化妆品含有美白剂。
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