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公开(公告)号：US20080199921A1
公开(公告)日：2008-08-21
申请号：US12108889
申请日：2008-04-24
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
IPC分类号： C12P17/10
摘要： The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
摘要翻译： 本发明涉及通过在式（2）的存在下将式（1）的取代的α-酮酸转化为式（2）的谷氨酸衍生物而有效地生产谷氨酸衍生物（包括其盐）的莫纳甜的方法 催化其转化。
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公开(公告)号：US20070072277A1
公开(公告)日：2007-03-29
申请号：US11561665
申请日：2006-11-20
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
摘要： The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
摘要翻译： 本发明涉及通过在式（2）的存在下将式（1）的取代的α-酮酸转化为式（2）的谷氨酸衍生物而有效地生产谷氨酸衍生物（包括其盐）的莫纳甜的方法 催化其转化。
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公开(公告)号：US08563278B2
公开(公告)日：2013-10-22
申请号：US12853844
申请日：2010-08-10
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
摘要： A process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin is described. This process entails converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
摘要翻译： 描述了有效制备谷氨酸衍生物（包括其盐）如莫纳甜的方法。 该方法需要在其催化转化酶的存在下将式（1）的取代的α-酮酸转化成式（2）的谷氨酸衍生物。
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公开(公告)号：US20100261234A1
公开(公告)日：2010-10-14
申请号：US12768360
申请日：2010-04-27
申请人： Masakazu SUGIYAMA , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
发明人： Masakazu SUGIYAMA , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
IPC分类号： C12P17/10
摘要： The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
摘要翻译： 本发明涉及通过在式（2）的存在下将式（1）的取代的α-酮酸转化为式（2）的谷氨酸衍生物而有效地制备谷氨酸衍生物（包括其盐）如莫纳甜的方法 催化其转化。
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公开(公告)号：US07297800B2
公开(公告)日：2007-11-20
申请号：US10876468
申请日：2004-06-28
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
IPC分类号： C07D209/00 , C12P17/00
摘要： The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same
摘要翻译： 本发明涉及通过在式（2）的存在下将式（1）的取代的α-酮酸转化为式（2）的谷氨酸衍生物而有效地生产谷氨酸衍生物（包括其盐）的莫纳甜的方法 催化其转化
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公开(公告)号：US20050009153A1
公开(公告)日：2005-01-13
申请号：US10876468
申请日：2004-06-28
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
摘要： The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
摘要翻译： 本发明涉及通过在式（2）的存在下将式（1）的取代的α-酮酸转化为式（2）的谷氨酸衍生物而有效地生产谷氨酸衍生物（包括其盐）的莫纳甜的方法 催化其转化。
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公开(公告)号：US08535920B2
公开(公告)日：2013-09-17
申请号：US11561665
申请日：2006-11-20
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
摘要： The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
摘要翻译： 本发明涉及通过在式（2）的存在下将式（1）的取代的α-酮酸转化为式（2）的谷氨酸衍生物而有效地生产谷氨酸衍生物（包括其盐）的莫纳甜的方法 催化其转化。
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公开(公告)号：US08202711B2
公开(公告)日：2012-06-19
申请号：US12768360
申请日：2010-04-27
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
摘要： The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
摘要翻译： 本发明涉及通过在式（2）的存在下将式（1）的取代的α-酮酸转化为式（2）的谷氨酸衍生物而有效地制备谷氨酸衍生物（包括其盐）如莫纳甜的方法 催化其转化。
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9.发明授权公开(公告)号：US07390909B2
公开(公告)日：2008-06-24
申请号：US11283943
申请日：2005-11-22
IPC分类号： C07D209/18
CPC分类号： C07D209/20 , A23L2/60 , A23L27/30 , A23L27/32 , C07C51/38 , C07C229/24 , C07C229/36 , C07D209/08 , C07D209/18 , C07C59/347
摘要： The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
摘要翻译： 本发明涉及制备谷氨酸化合物的方法，例如莫纳甜，其可用作例如甜味剂或药物产品的生产中间体。
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公开(公告)号：US07064219B2
公开(公告)日：2006-06-20
申请号：US10872573
申请日：2004-06-22
IPC分类号： C07D209/18
CPC分类号： C07D209/20 , A23L2/60 , A23L27/30 , A23L27/32 , C07C51/38 , C07C229/24 , C07C229/36 , C07D209/08 , C07D209/18 , C07C59/347
摘要： The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
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