摘要:
A compound of the formula: wherein R1 represents a lower alkyl; R2 represents H, an optionally substituted alkyl or an optionally substituted alkenyl; R3 and R4 each represents an optionally substituted lower alkyl or a lower alkoxy, or R3 and R4 form, taken together, an optionally substituted butadienylene; and X1 and X2 each represents an optionally esterified or etherified hydroxy, or a salt thereof is useful for protecting cells from the cytotoxicity of &bgr;-amyloid protein.
摘要翻译:下式的化合物:其中R 1表示低级烷基; R 2表示H,任选取代的烷基或任选取代的烯基; R 3和R 4各自表示任选取代的低级烷基或低级烷氧基,或者R 3和R 4一起形成任选取代的亚二烯基; 并且X 1和X 2各自表示任选酯化或醚化的羟基,或其盐可用于保护细胞免受β-淀粉样蛋白的细胞毒性。
摘要:
A novel compound of the formula: ##STR1## wherein Ar represents an optionally substituted tricyclic condensed benzene ring group which includes at least one heterocyclic ring as a component ring; n represents an integer from 2 to 10; R.sup.1 represents H or an optionally substituted hydrocarbon group, which may be different from one another in the repetition of n; and Y represents an optionally substituted 4-piperidinyl, 1-piperazinyl or 4-benzyl-1-piperidinyl group, or a salt thereof, inhibiting excellent cholinesterase inhibitory activity and monoamine reuptake inhibitory activity, thus being useful as therapeutic and/or prophylactic medicaments of senile dementia.
摘要:
A novel compound of the formula: ##STR1## wherein Ar represents an optionally substituted tricyclic condensed benzene ring group which includes at least one heterocyclic ring as a component ring; n represents an integer from 2 to 10; R.sup.1 represents H or an optionally substituted hydrocarbon group, which may be different from one another in the repetition of n; and Y represents an optionally substituted 4-piperidinyl, 1-piperazinyl or 4-benzyl-1-piperidinyl group, or a salt thereof, inhibiting excellent cholinesterase inhibitory activity and monoamine reuptake inhibitory activity, thus being useful as therapeutic and/or prophylactic medicaments of senile dementia.
摘要:
The present invention provides a prophylactic or therapeutic agent for depression or anxiety disorders, comprising (S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide.
摘要:
By combining one or more drugs selected from the group consisting of sedative antidepressants and antihistamines with (S)—N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide, there is provided a prophylactic or therapeutic agent for sleep disorder that induces natural sleep, shortens sleep latency, increases deep sleep, is excellent in maintaining sleep, and exerts to attain appropriate sleep duration.
摘要:
The present invention provides a prophylactic or therapeutic agent for nocturnal conduct disorders associated with dementia, comprising (S)—N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide.
摘要:
A combination of (S)—N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide with a medicine capable of prolonging a slow-wave sleep time provides a preventive or therapeutic agent for sleep disorder that induces natural sleep, shortens sleep latency, increases deep sleep, excels in sleep maintenance and ensures an appropriate sleep time.
摘要:
A roof system utilizing a solar cell comprising a first modular roof member composed of a plurality of first light collecting plate segments each of which having a solar cell embedded therein, the first light collecting plate segments being aligned in one direction and in the other direction perpendicular to the one direction; and a second modular roof member composed of a plurality of second light collecting plate segments each of which is equal in size to the first light collecting plate segment, the second light collecting plate segments being aligned in one direction and in the other direction perpendicular to the one direction, the number of the second light collecting plate segments in one direction being larger by one than that of the first light collecting plate segments.
摘要:
The image pickup system is constituted by a lens apparatus including a focus lens and an image pickup apparatus performing image pickup through the lens apparatus. The system includes an operating part being operated to instruct a movement of the focus lens, a controller performing focus position control to move the focus lens to a position corresponding to an operation amount of the operating part, a ranging part detecting an object distance in each of plural ranging areas included in an image pickup region, and a determining part determining a distance range where the object distances detected in the plural ranging areas are distributed. The system further includes a changing part changing a relationship between the operation amount of the operating part and the position of the focus lens in the focus position control according to a determination result by the determining part.
摘要:
In S104, it is determined whether an instruction has been input to drive a wiper serving as an optional member. If a wiper driving instruction has been input, the process shifts to S105 to perform wiper driving control. If no wiper driving instruction has been input, the process shifts to S106. In S106, it is determined whether the wiper is during driving. If the wiper is during driving, the process shifts to S107. If the wiper is not during driving, the process shifts to S113. In S107, it is determined whether information of the capacity of current suppliable from a television camera (2) to a television lens (1) has been output. Also in S107, the current capacity information is monitored. If no current capacity information has been output or the current capacity is small, the process shifts to S108 to stop driving control of a focus lens and zoom lens.