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公开(公告)号:US20200179050A1
公开(公告)日:2020-06-11
申请号:US16782029
申请日:2020-02-04
Applicant: President and Fellows of Harvard College , The Brigham and Women's Hospital , Children's Medical Center Corporation , Massachusetts Institute of Technology
Inventor: Conor J. Walsh , Ellen T. Roche , Panagiotis Polygerinos , Lucia R. Schuster , Jeffrey Michael Karp , Yuhan Lee , Pedro J. del Nido , Assunta Fabozzo , Ingeborg Friehs , Steven Charles Wasserman
Abstract: An insertable catheter device includes a shaft including a proximal end and a distal end, an expandable balloon, and an actuator configured to expand and retract the expandable balloon. The actuator includes a fluid conduit that extends through the shaft and is coupled with the expandable balloon to enable inflation and retraction of the expandable balloon via injection or withdrawal of a fluid to or from the expandable balloon via the fluid conduit. The expandable balloon is displaceably retractable into the shaft and extendable from the shaft. A fluid pump is coupled with the fluid conduit to pump the fluid through the fluid conduit. A patch is positioned to be displaced by the expandable balloon when the expandable balloon is inflated, and the expandable balloon is displaceably retractable into the shaft and displaceably extendable from the shaft.
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公开(公告)号:US20210350725A1
公开(公告)日:2021-11-11
申请号:US17193910
申请日:2021-03-05
Applicant: Massachusetts Institute of Technology
Inventor: Clara Park , Xuanhe Zhao , Hyunwoo Yuk , Christopher Tam Nguyen , Ellen T. Roche
Abstract: A biorobotic hybrid heart that preserves organic intracardiac structures and mimics cardiac motion by image-guided replication of the cardiac myofiber architecture of the left ventricle with an active synthetic myocardium that drives the motion of the heart. The active soft tissue mimic is adhered to the organic endocardial tissue in a helical fashion using a custom-designed adhesive to form a flexible, conformable, and watertight organosynthetic interface.
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公开(公告)号:US11627949B2
公开(公告)日:2023-04-18
申请号:US16782029
申请日:2020-02-04
Applicant: President and Fellows of Harvard College , The Brigham and Women's Hospital , Children's Medical Center Corporation , Massachusetts Institute of Technology
Inventor: Conor J. Walsh , Ellen T. Roche , Panagiotis Polygerinos , Lucia R. Schuster , Jeffrey Michael Karp , Yuhan Lee , Pedro J. del Nido , Assunta Fabozzo , Ingeborg Friehs , Steven Charles Wasserman
Abstract: An insertable catheter device includes a shaft including a proximal end and a distal end, an expandable balloon, and an actuator configured to expand and retract the expandable balloon. The actuator includes a fluid conduit that extends through the shaft and is coupled with the expandable balloon to enable inflation and retraction of the expandable balloon via injection or withdrawal of a fluid to or from the expandable balloon via the fluid conduit. The expandable balloon is displaceably retractable into the shaft and extendable from the shaft. A fluid pump is coupled with the fluid conduit to pump the fluid through the fluid conduit. A patch is positioned to be displaced by the expandable balloon when the expandable balloon is inflated, and the expandable balloon is displaceably retractable into the shaft and displaceably extendable from the shaft.
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公开(公告)号:US10588695B2
公开(公告)日:2020-03-17
申请号:US15310877
申请日:2015-05-13
Applicant: President and Fellows of Harvard College , The Brigham and Women's Hospital , Children's Medical Center Corporation , Massachusetts Institute of Technology
Inventor: Conor J. Walsh , Ellen T. Roche , Panagiotis Polygerinos , Lucia R. Schuster , Jeffrey Michael Karp , Yuhan Lee , Pedro J. del Nido , Assunta Fabozzo , Ingeborg Friehs , Steven Charles Wasserman
Abstract: An insertable light-dispensing catheter device, comprising a shaft including a proximal and distal end, a light guide extending through the shaft, and a mirror displaceably extendable from the catheter into a position where the mirror receives and reflects light emitted from the light guide. The mirror can be in the form of a coating on an inflatable balloon; and the balloon, when inflated, can press a patch against a defect (e.g., a ventricular septical defect), while the light cures an adhesive that binds the patch to the structure with the defect, thereby remedying the defect.
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公开(公告)号:US20230248566A1
公开(公告)日:2023-08-10
申请号:US18010617
申请日:2021-06-17
Applicant: Jose VENEGAS , United States Government as Represented by the Department of Veterans Affairs , MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventor: RAVI RASALINGAM , TARSHA WARD , JOSE VENEGAS , Ellen T. Roche
CPC classification number: A61F5/566 , A61M16/0009
Abstract: An oral appliance and method for treating a sleep disorder in a subject are disclosed. The appliance includes, among other elements, a palatal overlay element that engages a portion of the dorsal surface of the subject's tongue, stabilizing the tongue in a superior direction toward the hard palate. The method generally involves stabilizing the dorsal surface of a subject's tongue in a superior direction toward the subject's hard palate.
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公开(公告)号:US20170079717A1
公开(公告)日:2017-03-23
申请号:US15310877
申请日:2015-05-13
Applicant: President and Fellows of Harvard College , The Brigham and Women's Hospital , Children's Medical Center Corporation , Massachusetts Institute of Technology
Inventor: Conor J. Walsh , Ellen T. Roche , Panagiotis Polygerinos , Lucia R. Schuster , Jeffrey Michael Karp , Yuhan Lee , Pedro J. del Nido , Assunta Fabozzo , Ingeborg Friehs , Steven Charles Wasserman
CPC classification number: A61B18/24 , A61B17/00491 , A61B17/0057 , A61B17/12113 , A61B17/12122 , A61B17/12131 , A61B2017/00039 , A61B2017/00243 , A61B2017/005 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00601 , A61B2017/0061 , A61B2017/00623 , A61B2017/0065 , A61B2017/00818 , A61B2017/00893 , A61B2017/00907 , A61B2017/12054 , A61B2018/0022 , A61B2018/00285 , A61B2018/00351 , A61B2018/00416 , A61B2018/00494 , A61B2018/00517 , A61B2018/00839 , A61B2018/00982 , A61B2018/2261 , A61B2018/2272 , A61F2/0063 , A61M25/0067
Abstract: An insertable light-dispensing catheter device, comprising a shaft including a proximal and distal end, a light guide extending through the shaft, and a mirror displaceably extendable from the catheter into a position where the mirror receives and reflects light emitted from the light guide. The mirror can be in the form of a coating on an inflatable balloon; and the balloon, when inflated, can press a patch against a defect (e.g., a ventricular septical defect), while the light cures an adhesive that binds the patch to the structure with the defect, thereby remedying the defect.
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