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公开(公告)号：US20150148791A1
公开(公告)日：2015-05-28
申请号：US14356151
申请日：2012-11-02
发明人： Matthew Birdsall , Gabriel Brennan , Anthony Bertrand , Brian Donlon , Kara Harrington , Brian Kelly , Micheal Moriarty , Stephen Nash , Elger Oberwelz , Fiachra Sweeney , Roman Turovskiy
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B34/25 , A61B90/39 , A61B2018/00041 , A61B2018/00166 , A61B2018/00172 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00642 , A61B2018/00672 , A61B2018/00678 , A61B2018/00744 , A61B2018/00761 , A61B2018/00821 , A61B2018/00863 , A61B2018/0212 , A61B2018/0268 , A61B2090/064
摘要： Cryotherapeutic systems and cryotherapeutic-system components configured for renal neuromodulation are disclosed herein. A cryotherapeutic system configured in accordance with a particular embodiment of the present technology can include a console having a cartridge housing, a cartridge connector adjacent to the cartridge housing, and a supply passage fluidly connected to the cartridge connector. The console can further include a supply valve along the supply passage and a control assembly including a supply-valve actuator and a user interface. The supply-valve actuator can be operably connected to the supply valve, and the control assembly can be configured to signal the supply-valve actuator to open the supply valve in response to a signal from the user interface.
摘要翻译： 本文公开了配置用于肾神经调节的冷冻治疗系统和冷冻治疗系统组件。 根据本技术的特定实施例配置的冷冻治疗系统可以包括具有盒壳体，与盒壳体相邻的盒式连接器的控制台和与盒连接器流体连接的供应通道。 控制台还可以包括沿着供应通道的供给阀和包括供给阀致动器和用户界面的控制组件。 供应阀致动器可以可操作地连接到供应阀，并且控制组件可以被配置为响应于来自用户界面的信号而使供应阀致动器发信号以打开供应阀。
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公开(公告)号：US20190183556A1
公开(公告)日：2019-06-20
申请号：US16221174
申请日：2018-12-14
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Mark Gelfand , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Mark S. Leung , Gwenda McMullin , Barry Mullins , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vicenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Michael Turovskiy
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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公开(公告)号：US10188445B2
公开(公告)日：2019-01-29
申请号：US15229761
申请日：2016-08-05
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Mark Gelfand , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Mark S. Leung , Gwenda Francis , Barry Mullins , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Michael Turovskiy
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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4.发明申请公开(公告)号：US20170056087A1
公开(公告)日：2017-03-02
申请号：US15229761
申请日：2016-08-05
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Mark Gelfand , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Mark S. Leung , Gwenda McMullin , Barry Mullins , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vicenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Michael Turovskiy
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
摘要翻译： 本文公开了神经调节冷冻治疗装置及相关系统和方法。 根据本技术的特定实施例配置的冷冻治疗装置可以包括细长轴，其具有沿轴的至少一部分的远侧部分和供应内腔。 轴可以被配置为将远端部分血管内定位在肾动脉或肾口附近的治疗部位。 供应内腔可被配置为接收液体制冷剂。 冷冻治疗装置还可以包括在轴的远端处的冷却组件。 冷却组件可以包括与供应内腔流体连通的施加器，并且构造成当冷却组件处于展开状态时，将冷冻治疗冷却递送到靠近目标部位的神经。
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公开(公告)号：US20210068886A1
公开(公告)日：2021-03-11
申请号：US17099465
申请日：2020-11-16
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Mark Gelfand , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Mark S. Leung , Gwenda Francis , Barry Mullins , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Michael Turovskiy
IPC分类号： A61B18/02
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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