-
公开(公告)号：US20110212939A1
公开(公告)日：2011-09-01
申请号：US13003571
申请日：2009-07-10
申请人： Lisa Sarah Bertram , Philip Graham Clarke , Graham John Dawson , Peter Timothy Fry , Matthew Colin Thor Fyfe , William Gattrell , Revathy Perpetua Jeevaratnam , John Keily , Thomas Martin Krulle , Martin James Procter , Chrystelle Marie Rasamison , Colin Peter Sambrook-Smith , Simon Andrew Swain
发明人： Lisa Sarah Bertram , Philip Graham Clarke , Graham John Dawson , Peter Timothy Fry , Matthew Colin Thor Fyfe , William Gattrell , Revathy Perpetua Jeevaratnam , John Keily , Thomas Martin Krulle , Martin James Procter , Chrystelle Marie Rasamison , Colin Peter Sambrook-Smith , Simon Andrew Swain
IPC分类号： A61K31/397 , C07D401/04 , A61K31/506 , C07D401/14 , A61K31/4965 , A61K31/454 , A61K31/4725 , A61K31/4709 , A61K31/517 , A61P3/00
CPC分类号： C07D401/12 , C07D295/205 , C07D401/04 , C07D401/14 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/14
摘要： Compounds of formula (I) or pharmaceutically acceptable salts thereof, are GPCR (GPR119) agonists and are useful as for the treatment of diabetes and obesity.
摘要翻译： 式（I）化合物或其药学上可接受的盐是GPCR（GPR119）激动剂，可用于治疗糖尿病和肥胖症。
-
公开(公告)号：US20100022591A1
公开(公告)日：2010-01-28
申请号：US12522018
申请日：2008-01-04
申请人： Lisa Sarah Bertram , Matthew Colin Thor Fyfe , Revathy Perpetua Jeevaratnam , John Keily , Simon Andrew Swain
发明人： Lisa Sarah Bertram , Matthew Colin Thor Fyfe , Revathy Perpetua Jeevaratnam , John Keily , Simon Andrew Swain
IPC分类号： A61K31/454 , C07D401/04 , A61P3/10 , A61P9/10 , A61P3/04
CPC分类号： C07D413/04
摘要： Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.
摘要翻译： 式（I）化合物或其药学上可接受的盐是GPCR激动剂，可用于治疗肥胖症和糖尿病。
-
公开(公告)号：US20100105732A1
公开(公告)日：2010-04-29
申请号：US12522023
申请日：2008-01-04
申请人： Matthew Colin Thor Fyfe , Revathy Perpetua Jeevaratnam , John Keily , Simon Andrew Swain , Lisa Sarah Bertram
发明人： Matthew Colin Thor Fyfe , Revathy Perpetua Jeevaratnam , John Keily , Simon Andrew Swain , Lisa Sarah Bertram
IPC分类号： A61K31/4545 , C07D213/71 , C07D213/82 , A61P3/04 , A61P3/10 , A61P3/00 , A61P9/12 , A61P9/10 , A61P9/00
CPC分类号： C07D413/14
摘要： Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.
-
公开(公告)号：US20120172358A1
公开(公告)日：2012-07-05
申请号：US13396193
申请日：2012-02-14
申请人： Stuart Edward Bradley , Matthew Colin Thor Fyfe , Lisa Sarah Bertram , William Gattrell , Revathy Perpetua Jeevaratnam , John Keily , Martin James Procter , Chrystelle Marie Rasamison , Philip John Rushworth , Colin Peter Sambrook-Smith , David French Stonehouse , Simon Andrew Swain , Geoffrey Martyn Williams
发明人： Stuart Edward Bradley , Matthew Colin Thor Fyfe , Lisa Sarah Bertram , William Gattrell , Revathy Perpetua Jeevaratnam , John Keily , Martin James Procter , Chrystelle Marie Rasamison , Philip John Rushworth , Colin Peter Sambrook-Smith , David French Stonehouse , Simon Andrew Swain , Geoffrey Martyn Williams
IPC分类号： A61K31/445 , C07D401/10 , C07D413/12 , C07D401/04 , A61K31/454 , A61P3/06 , A61K31/496 , A61K31/5377 , A61K31/506 , A61P3/00 , A61P3/04 , A61P3/10 , C07D211/34 , A61K31/4545
CPC分类号： C07D401/14 , C07D211/20 , C07D211/22 , C07D211/24 , C07D211/26 , C07D211/28 , C07D211/34 , C07D211/48 , C07D401/04 , C07D401/10 , C07D401/12
摘要： Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.
摘要翻译： 式（I）化合物或其药学上可接受的盐是GPCR激动剂，可用于治疗肥胖症和糖尿病。
-
公开(公告)号：US20110269734A1
公开(公告)日：2011-11-03
申请号：US13003546
申请日：2009-07-10
申请人： Lisa Sarah Bertram , Matthew Colin Thor Fyfe , Revathy Perpetua Jeevaratnam , John Keily , Thomas Martin Krulle , Chrystelle Marie Rasamison , Colin Peter Sambrook-Smith , Simon Andrew Swain
发明人： Lisa Sarah Bertram , Matthew Colin Thor Fyfe , Revathy Perpetua Jeevaratnam , John Keily , Thomas Martin Krulle , Chrystelle Marie Rasamison , Colin Peter Sambrook-Smith , Simon Andrew Swain
IPC分类号： A61K31/397 , A61K31/506 , C07D401/14 , A61P9/12 , A61K31/4545 , A61P3/04 , A61P3/10 , A61P3/06 , C07D401/04 , A61K31/501
CPC分类号： C07D401/04 , C07D401/14
摘要： Compounds of formula (I):or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of diabetes and obesity.
摘要翻译： 式（I）化合物或其药学上可接受的盐是GPCR激动剂，可用于治疗糖尿病和肥胖症。
-
公开(公告)号：US20120214808A1
公开(公告)日：2012-08-23
申请号：US13399517
申请日：2012-02-17
申请人： Jason Bloxham , Matthew Colin Thor Fyfe , James Horswill , Revathy Perpetua Jeevaratnam , John Keily , Martin James Procter , Karen Lesley Schofield , Salam Shaaban , Simon Andrew Swain , Philippe Wong-Kai-In
发明人： Jason Bloxham , Matthew Colin Thor Fyfe , James Horswill , Revathy Perpetua Jeevaratnam , John Keily , Martin James Procter , Karen Lesley Schofield , Salam Shaaban , Simon Andrew Swain , Philippe Wong-Kai-In
IPC分类号： A61K31/5377 , C07D277/38 , A61K31/381 , C07D333/50 , C07D333/36 , A61K31/17 , C07C275/42 , A61K31/4164 , C07D233/56 , A61K31/428 , C07D277/82 , A61K31/44 , C07D213/72 , A61K31/5375 , C07D295/12 , A61K31/505 , C07D239/02 , C07D413/04 , A61P3/04 , A61P25/18 , A61P25/24 , A61P3/00 , A61P25/08 , A61P25/00 , A61K31/426
CPC分类号： A61K31/381 , A61K31/341 , A61K31/404 , A61K31/426 , A61K31/428 , A61K31/44 , A61K31/455
摘要： A method of treating a condition associated with the CB-1 receptor, in particular obesity, by administering an effective amount of an aryl urea CB-1 receptor modulating compound to a subject in need of such treatment.
摘要翻译： 通过向需要这种治疗的受试者施用有效量的芳基脲CB-1受体调节化合物来治疗与CB-1受体相关的病症，特别是肥胖症的方法。
-
公开(公告)号：US20100048625A1
公开(公告)日：2010-02-25
申请号：US12522030
申请日：2008-01-04
IPC分类号： A61K31/4545 , C07D413/14 , A61P3/00 , A61P3/04 , A61P3/10
CPC分类号： C07D413/14
摘要： Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.
-
公开(公告)号：US20120040953A1
公开(公告)日：2012-02-16
申请号：US13255536
申请日：2010-03-12
申请人： Oscar Barba , Susan Helen Davis , Matthew Colin Thor Fyfe , Revathy Perpetua Jeevaratnam , Karen Lesley Schofield , Thomas Staroske , Alan John William Stewart , Simon Andrew Swain , David Matthew Withall
发明人： Oscar Barba , Susan Helen Davis , Matthew Colin Thor Fyfe , Revathy Perpetua Jeevaratnam , Karen Lesley Schofield , Thomas Staroske , Alan John William Stewart , Simon Andrew Swain , David Matthew Withall
IPC分类号： A61K31/506 , A61K31/4545 , C07D401/14 , A61P3/06 , A61P3/00 , A61P3/04 , C07D413/14 , A61K31/501 , A61P3/10
CPC分类号： C07D413/14
摘要： The present invention is directed to therapeutic compounds which have activity as agonists of GPR119 and are useful for the treatment of metabolic disorders including type II diabetes.
摘要翻译： 本发明涉及具有作为GPR119激动剂的活性并且可用于治疗包括II型糖尿病的代谢性疾病的治疗性化合物。
-
公开(公告)号：US20120059014A1
公开(公告)日：2012-03-08
申请号：US13255531
申请日：2010-03-12
申请人： Oscar Barba , Tom Banksia Dupree , Peter Timothy Fry , Matthew Colin Thor Fyfe , Revathy Perpetua Jeevaratnam , Thomas Martin Krulle , Karen Lesley Schofield , Donald Smyth , Thomas Staroske , Alan John William Stewart , David French Stonehouse , Simon Andrew Swain , David Matthew Withall
发明人： Oscar Barba , Tom Banksia Dupree , Peter Timothy Fry , Matthew Colin Thor Fyfe , Revathy Perpetua Jeevaratnam , Thomas Martin Krulle , Karen Lesley Schofield , Donald Smyth , Thomas Staroske , Alan John William Stewart , David French Stonehouse , Simon Andrew Swain , David Matthew Withall
IPC分类号： A61K31/506 , C07D413/14 , A61K31/4545 , A61K31/501 , A61P9/12 , A61P3/04 , A61P3/00 , A61P3/08 , A61P3/06 , A61P7/00 , C07D401/14 , A61P3/10
CPC分类号： C07D403/12
摘要： The present invention is directed to therapeutic compounds of the following formula (I) which have activity as agonists of GPR119 and are useful for the treatment of metabolic disorders including type II diabetes.
摘要翻译： 本发明涉及具有作为GPR119激动剂的活性的下式（I）的治疗性化合物，并且可用于治疗包括II型糖尿病的代谢紊乱。
-
公开(公告)号：US20120077793A1
公开(公告)日：2012-03-29
申请号：US13255525
申请日：2010-03-12
申请人： Oscar Barba , Peter Timothy Fry , Matthew Colin Thor Fyfe , William Gattrell , Revathy Perpetua Jeevaratnam , Thomas Martin Krulle , Martin James Procter , Colin Peter Sambrook-Smith , Karen Lesley Schofield , Donald Smyth , Alan John William Stewart , David French Stonehouse , Simon Andrew Swain
发明人： Oscar Barba , Peter Timothy Fry , Matthew Colin Thor Fyfe , William Gattrell , Revathy Perpetua Jeevaratnam , Thomas Martin Krulle , Martin James Procter , Colin Peter Sambrook-Smith , Karen Lesley Schofield , Donald Smyth , Alan John William Stewart , David French Stonehouse , Simon Andrew Swain
IPC分类号： A61K31/4439 , A61K31/4545 , C07D401/12 , A61K31/454 , A61K31/497 , A61P9/12 , A61K31/4725 , A61P3/10 , A61P3/04 , A61P3/00 , A61P3/08 , A61P3/06 , C07D401/14 , C07D413/14
CPC分类号： C07D401/12 , C07D213/64 , C07D401/14 , C07D403/14 , C07D413/14
摘要： The present invention is directed to therapeutic compounds which have activity as agonists of GPR119 and are useful for the treatment of metabolic disorders including type II diabetes.
-
-
-
-
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.033 秒)
