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    Apparatus and method for treating articles in solution with effervescent tablets
    4.
    发明授权
    Apparatus and method for treating articles in solution with effervescent tablets 失效
    用泡腾片处理溶液中的制品的装置和方法

    公开(公告)号：US5756044A

    公开(公告)日：1998-05-26

    申请号：US629715

    申请日：1996-04-09

    申请人： Mary Mowrey-McKee ,  Rafael Victor Andino ,  David N. Ku ,  Paul J. Mulhauser ,  David R. Schiff

    发明人： Mary Mowrey-McKee ,  Rafael Victor Andino ,  David N. Ku ,  Paul J. Mulhauser ,  David R. Schiff

    IPC分类号： A61L2/16 ,  A45C11/00 ,  A61L12/08 ,  A61L2/00

    CPC分类号： A61L12/08 ,  A45C11/005

    摘要： An article treatment system which provides improved solution mixing and concentration uniformity. The treatment system includes a container, a closure and a channel for guiding fluid flow. The treatment system is especially advantageous for use with effervescent tablets and for use in treating contact lenses. Cleaning and disinfecting of articles is improved by use of a tubular channel which guides upwardly gas and other components released from an effervescent tablet which is located at the bottom of the treatment container. The upward central flow through the channel induces a downward flow between the container walls, the exterior walls of the channel, and the article-retaining means and towards the bottom of the container.

    摘要翻译： 一种提供改进的溶液混合和浓度均匀性的制品处理系统。 处理系统包括容器，封闭件和用于引导流体流动的通道。 治疗系统特别适用于泡腾片剂和用于治疗隐形眼镜。 通过使用引导向上的气体和从位于处理容器底部的泡腾片剂释放的其它组分的管状通道来改善制品的清洁和消毒。 通过通道的向上的中心流在容器壁，通道的外壁和物品保持装置之间并朝向容器的底部引起向下的流动。

    Surgical bone cutting assembly and method of using same
    6.
    发明授权
    Surgical bone cutting assembly and method of using same 有权
    手术骨切割组件及其使用方法

    公开(公告)号：US08152808B2

    公开(公告)日：2012-04-10

    申请号：US12453998

    申请日：2009-05-28

    申请人： Anton J. Steiner ,  David I. Knight ,  Paul J. Mulhauser ,  Karl D. Kirk, III ,  Richard J. Cosenza ,  Gregory C. Fanelli

    发明人： Anton J. Steiner ,  David I. Knight ,  Paul J. Mulhauser ,  Karl D. Kirk, III ,  Richard J. Cosenza ,  Gregory C. Fanelli

    IPC分类号： A61B17/00

    CPC分类号： A61B17/1675 ,  A61B17/1604 ,  A61B17/32053 ,  A61B2090/061

    摘要： The invention is directed toward a surgical kit having component parts capable of use in excising a cartilage defect site on a patient to prepare the same for receipt of an implant plug, the kit comprising a cylindrical gauge with a central bore used to measure the defect area, a guide rod adapted to be driven through the gauge tube into the center of said defect area and a cartilage cutting assembly adapted to be mounted over the guide rod and used for excising the defect area and cutting a cylindrical bore into the defect area. The method for use of the kit comprises the steps of: marking the defect area to be cut; placing a guide rod into the center defect area and driving the same to a predetermined distance to secure the same in the defect area and placing a drill bit over the guide rod and rotating the drill bit to cut a cylindrical blind bore removing the cartilage defect.

    摘要翻译： 本发明涉及一种手术套件，其具有能够用于切除患者上的软骨缺损部位以准备接收植入物塞的组件的套件，该套件包括具有用于测量缺陷区域的中心孔的圆柱形计量器 ，适于被驱动通过所述计量管进入所述缺陷区域的中心的导杆和软管切割组件，所述软骨切割组件适于安装在导杆上并用于切除缺陷区域并将圆柱形孔切割到缺陷区域中。 使用该试剂盒的方法包括以下步骤：标记要切割的缺陷区域; 将导杆放置在中心缺陷区域并将其驱动到预定距离以将其固定在缺陷区域中，并将钻头放置在导杆上并旋转钻头以切割圆柱形盲孔，从而去除软骨缺损。

    Implantable therapy systems and methods
    9.
    发明授权
    Implantable therapy systems and methods 失效
    植入式治疗系统和方法

    公开(公告)号：US06179826B2

    公开(公告)日：2001-01-30

    申请号：US08741228

    申请日：1996-10-29

    申请人： Patrick Aebischer ,  Moses Goddard ,  John G. Moldauer ,  Paul J. Mulhauser ,  Anne M. Rathbun ,  Paul R. Sanberg ,  Alfred V. Vasconcellos ,  Nicholas F. Warner

    发明人： Patrick Aebischer ,  Moses Goddard ,  John G. Moldauer ,  Paul J. Mulhauser ,  Anne M. Rathbun ,  Paul R. Sanberg ,  Alfred V. Vasconcellos ,  Nicholas F. Warner

    IPC分类号： A61M3100

    CPC分类号： A61K9/0092 ,  A61F2/022 ,  A61K9/0024 ,  A61K9/0085 ,  A61K35/55 ,  A61K2035/126 ,  A61M31/002 ,  A61M37/0069 ,  A61M39/0208 ,  A61M2210/0687 ,  A61M2210/0693 ,  B01J13/02 ,  C12N5/0012 ,  C12N5/0614 ,  C12N5/0619 ,  C12N5/0676 ,  C12N11/04 ,  C12N2533/30 ,  A61M2230/005

    摘要： Implantable therapy systems are disclosed for the local and controlled delivery of a biologically active factor to the brain, spinal cord and other target regions of a subject suffering from a dibilatating condition. The method of the invention involves surgically exposing an insertion site, generally located above a predetermined treatment site (12), in a patient. A cannula (20), having an obturator (30) or dilator (104) positioned therein, is inserted at the insertion site, defining a pathway to the treatment site. In some instances, the cannula can be inserted along the path of a guidewire (102) previously positioned at the treatment site. The cannula (20) is preferably a low friction polymeric material such as polytetrafluoroethylene. The cannula (20) generally has an open proximal end for receiving the obturator (30) or dilator (104), and an open distal end, preferably a tapered end, for delivery of neurologically active factors to the treatment site (12). The obturator (30) is then removed from the cannula (20), and a biocompatible tethered vehicle (40) containing a biologically active material is inserted into the cannula along the passageway. A pusher can be inserted within the cannula, behind the vehicle (40), to position the proximal end of the vehicle at the proximal tip of the cannula (20b). Once the vehicle (40) is positioned near the proximal end of the cannula (20), the cannula is removed from the passageway, followed by the pusher, leaving the vehicle (40) positioned at the treatment site (12).

    摘要翻译： 公开了植入式治疗系统，用于将局部和受控制的生物活性因子递送至患有二体化病症的受试者的脑，脊髓和其他靶区域。 本发明的方法涉及通常在患者体内暴露通常位于预定治疗部位（12）上方的插入部位。 具有定位在其中的闭塞器（30）或扩张器（104）的插管（20）插入插入位置，从而限定到治疗部位的通路。 在一些情况下，套管可以沿着预先位于治疗部位的导丝（102）的路径插入。 插管（20）优选为低摩擦聚合材料，例如聚四氟乙烯。 插管（20）通常具有用于接收封闭器（30）或扩张器（104）的开放近端，以及用于将神经活性因子递送至治疗部位（12）的开口远端，优选地为锥形末端。 然后将塞子（30）从插管（20）中取出，并且将包含生物活性物质的生物相容性系留载体（40）沿通道插入插管中。 推动器可以插入插管内，在车辆（40）后面，以将车辆的近端定位在套管（20b）的近端处。 一旦车辆（40）定位在套管（20）的近端附近，则套管从通道中移开，随后是推动器，使车辆（40）位于治疗部位（12）处。