公开(公告)号：US20140120604A1

公开(公告)日：2014-05-01

申请号：US14110635

申请日：2012-04-06

申请人： Mauro Aguanno ,  Brian Barrett ,  Brian Chawke ,  Kieran Curran ,  Damian Curtin ,  Tara Dalton ,  Mark Davies ,  Xiaona Hou ,  David Kinahan ,  Damien King ,  Mark Korenke ,  Conor McCarthy ,  David McGuire ,  Michael Sayers ,  Noel Sirr ,  Ryan J. Talbot

发明人： Mauro Aguanno ,  Brian Barrett ,  Brian Chawke ,  Kieran Curran ,  Damian Curtin ,  Tara Dalton ,  Mark Davies ,  Xiaona Hou ,  David Kinahan ,  Damien King ,  Mark Korenke ,  Conor McCarthy ,  David McGuire ,  Michael Sayers ,  Noel Sirr ,  Ryan J. Talbot

IPC分类号： G01N21/64 ,  B01F13/00

CPC分类号： C12Q1/686 ,  B01F13/0005 ,  B01F13/0071 ,  B01F15/00214 ,  B01L3/502715 ,  B01L3/502784 ,  B01L7/52 ,  B01L7/525 ,  B01L2200/143 ,  B01L2300/06 ,  B01L2300/0654 ,  B01L2300/0867 ,  G01N21/6428 ,  G01N35/00623 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2035/00465 ,  G01N2201/062

摘要： Provided herein is a biological detection system and method of use wherein the biological detection system comprises at least one mixer or liquid bridge for combining at least two liquid droplets and an error correction system for detecting whether or not proper mixing or combining of the two component droplets have occurred.

摘要翻译： 本文提供了一种生物检测系统和使用方法，其中生物检测系统包括用于组合至少两个液滴的至少一个混合器或液体桥，以及用于检测是否适当混合或组合两个组分液滴的误差校正系统 已经发生

公开(公告)号：US20140111901A1

公开(公告)日：2014-04-24

申请号：US14110678

申请日：2012-04-06

申请人： Brian Chawke ,  Kieran Curran ,  David McGuire ,  Michael Sayers ,  Noel Sirr

发明人： Brian Chawke ,  Kieran Curran ,  David McGuire ,  Michael Sayers ,  Noel Sirr

IPC分类号： B01L3/00

CPC分类号： B01L3/50273 ,  B01F13/0071 ,  B01F13/0076 ,  B01J19/087 ,  B01L3/502715 ,  B01L3/502784 ,  B01L3/52 ,  B01L3/56 ,  B01L2200/0673 ,  B01L2300/0867 ,  B01L2400/0406 ,  B01L2400/0415 ,  B05B5/035 ,  C12Q1/686 ,  G01N1/38 ,  G01N2001/4038

摘要： Devices, systems, and methods for charging fluids are disclosed. The charging of fluids improves the mixing of fluids in microfluidic systems. The charging is performed by producing an ion field (50) between an ionizing electrode (20) and an opposed ground electrode (30). A fluid-containing vessel (40) is positioned between the opposed electrodes and the ion field charges the fluid (41) in the vessel.

摘要翻译： 公开了用于充液的装置，系统和方法。 流体充液改善了微流体系统中流体的混合。 通过在电离电极（20）和相对的接地电极（30）之间产生离子场（50）来进行充电。 流体容纳容器（40）位于相对的电极之间，离子场对容器中的流体（41）充电。

公开(公告)号：US20100304443A1

公开(公告)日：2010-12-02

申请号：US12732494

申请日：2010-03-26

申请人： Mark Davies ,  Tara Dalton ,  Michael Sayers ,  Brian Chawke

发明人： Mark Davies ,  Tara Dalton ,  Michael Sayers ,  Brian Chawke

IPC分类号： C12P19/34 ,  C12M1/26

CPC分类号： B01L3/021 ,  B01L3/0293 ,  B01L7/52 ,  B01L2200/0642 ,  B01L2200/0673 ,  Y10T436/25 ,  Y10T436/25625

摘要： The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including an outer sheath; a plurality of tubes within the sheath, in which at least one of the tubes acquires a sample, and at least one of the tubes expels a fluid that is immiscible with the sample, in which the at least one tube that acquires the sample is extendable beyond a distal end of the sheath and retractable to within the sheath; and a valve connected to a distal portion of the sheath, in which the valve opens when the tube extends beyond the distal end and closes when the tube retracts to within the sheath.

摘要翻译： 本发明一般涉及用于获取和/或分配样品而不将气体引入诸如液体桥系统的微流体系统中的装置，系统和方法。 示例性实施例提供了一种包括外护套的取样装置; 鞘内的多个管，其中至少一个管获取样品，并且至少一个管排出与样品不混溶的流体，其中获取样品的至少一个管可扩展 超出护套的远端并伸缩到护套内; 以及连接到所述护套的远端部分的阀，当所述管延伸超过所述远端时所述阀打开，并且当所述管缩回到所述护套内时所述阀闭合。

公开(公告)号：US08741660B2

公开(公告)日：2014-06-03

申请号：US12732494

申请日：2010-03-26

申请人： Mark Davies ,  Tara Dalton ,  Michael Sayers ,  Brian Chawke

发明人： Mark Davies ,  Tara Dalton ,  Michael Sayers ,  Brian Chawke

IPC分类号： G01N1/18

CPC分类号： B01L3/021 ,  B01L3/0293 ,  B01L7/52 ,  B01L2200/0642 ,  B01L2200/0673 ,  Y10T436/25 ,  Y10T436/25625

摘要： The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including an outer sheath; a plurality of tubes within the sheath, in which at least one of the tubes acquires a sample, and at least one of the tubes expels a fluid that is immiscible with the sample, in which the at least one tube that acquires the sample is extendable beyond a distal end of the sheath and retractable to within the sheath; and a valve connected to a distal portion of the sheath, in which the valve opens when the tube extends beyond the distal end and closes when the tube retracts to within the sheath.

摘要翻译： 本发明一般涉及用于获取和/或分配样品而不将气体引入诸如液体桥系统的微流体系统中的装置，系统和方法。 示例性实施例提供了一种包括外护套的取样装置; 鞘内的多个管，其中至少一个管获取样品，并且至少一个管排出与样品不混溶的流体，其中获取样品的至少一个管可扩展 超出护套的远端并伸缩到护套内; 以及连接到所述护套的远端部分的阀，当所述管延伸超过所述远端时所述阀打开，并且当所述管缩回到所述护套内时所述阀闭合。