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10 条记录 (耗时 0.025 秒)

    Suspension of sparingly water-soluble acidic drug
    1.
    发明授权
    Suspension of sparingly water-soluble acidic drug 失效
    悬浮微量水溶性酸性药物

    公开(公告)号：US06231890B1

    公开(公告)日：2001-05-15

    申请号：US09171631

    申请日：1998-10-22

    申请人： Mayumi Naito ,  Hiroshi Nakano ,  Kazuo Hasegawa ,  Toshiaki Nakajima ,  Ichiro Okudaira ,  Kenji Tsunoda

    发明人： Mayumi Naito ,  Hiroshi Nakano ,  Kazuo Hasegawa ,  Toshiaki Nakajima ,  Ichiro Okudaira ,  Kenji Tsunoda

    IPC分类号： A61K914

    CPC分类号： A61K9/0095

    摘要： A suspension of a sparingly water-soluble acidic drug, especially, a nonsteroidal anti-inflammatory analgesic agent, which is stable for a prolonged period of time and is highly dissolvable, and a process for simply and easily producing the suspension. This suspension has a pH value of 2 to 5 and comprises a sparingly water-soluble acidic drug whose average particle size ranges from 1 to 15 &mgr;m, a polyglycerol fatty acid ester, a water-soluble polyhydric alcohol and water, optionally, together with an inorganic powder having an average particle size of 1 to 15 &mgr;m. This process is characterized by carrying out pulverization and dispersion of a sparingly water-soluble acid drug, a polyglycerol fatty acid ester, a water-soluble polyhydric alcohol and water by means of a pulverizer comprising a main shaft adapted to rotate in a casing and a plurality of layshafts adapted to revolve in relationship interlocked with the rotation of the main shaft, each of the layshafts being fitted with a multiplicity of annular griding media.

    摘要翻译： 微溶水性酸性药物，特别是长时间稳定且非常可溶性的非甾体抗炎止痛剂的悬浮液，以及简单且容易地制备悬浮液的方法。 该悬浮液的pH值为2〜5，并且包含平均粒径为1〜15μm的微溶水性酸性药物，聚甘油脂肪酸酯，水溶性多元醇和水，任选地与 平均粒径为1〜15μm的无机粉末。 该方法的特征在于通过粉碎机进行微水溶性酸性药物，聚甘油脂肪酸酯，水溶性多元醇和水的粉碎和分散，所述粉碎机包括适于在壳体内旋转的主轴和 多个副轴适于以与主轴的旋转互锁的关系旋转，每个副轴装配有多个环形磨盘。

    Remedy for dermatitis
    2.
    发明授权
    Remedy for dermatitis 失效
    皮炎的补救措施

    公开(公告)号：US05997852A

    公开(公告)日：1999-12-07

    申请号：US875142

    申请日：1997-10-08

    申请人： Akiko Yoneda ,  Hideaki Kitajima ,  Kenji Tsunoda ,  Kazuo Hasegawa ,  Takako Ishii

    发明人： Akiko Yoneda ,  Hideaki Kitajima ,  Kenji Tsunoda ,  Kazuo Hasegawa ,  Takako Ishii

    IPC分类号： A61K33/30 ,  A61K7/06

    CPC分类号： A61K33/30

    摘要： A dermatitis-curing agent, characterized by comprising (A) a zinc compound and (B) at least one compound selected from the group consisting of multivalent unsaturated fatty acids and their esters as effective components is very effective for enteropathic acrodermatitis syndrome, and seborrheic dermatitis, psoriasis vulgaris, bullous dermatitis and puritus cutaneus, which show similar skin symptoms, or for symtoms due to zinc deficiency caused by injuries, burn injuries and frostbites.

    摘要翻译： PCT No.PCT / JP96 / 00064 Sec。 371日期1997年10月8日第 102（e）日期1997年10月8日PCT PCT 1996年1月18日PCT公布。 公开号WO96 / 22102 日期1996年7月25日一种皮炎治疗剂，其特征在于包含（A）锌化合物和（B）至少一种选自多价不饱和脂肪酸及其酯作为有效成分的化合物对于肠病性丙型鼻炎非常有效 综合征，脂溢性皮炎，寻常型牛皮癣，大疱性皮炎和睾酮，其具有相似的皮肤症状，或由于受伤，烧伤和冻伤引起的锌缺乏引起的症状。

    Cream
    5.
    发明授权
    Cream 失效
    奶油

    公开(公告)号：US4794106A

    公开(公告)日：1988-12-27

    申请号：US902002

    申请日：1986-08-28

    申请人： Yasuji Takashima ,  Shigeo Tanaka ,  Kenji Tsunoda ,  Ichirou Kawamata ,  Hiroshi Murayama

    发明人： Yasuji Takashima ,  Shigeo Tanaka ,  Kenji Tsunoda ,  Ichirou Kawamata ,  Hiroshi Murayama

    IPC分类号： A61K9/00 ,  A61K9/06 ,  A61K31/57 ,  A61K47/00 ,  A61P29/00 ,  A61K31/56 ,  A61K31/58 ,  C07J5/00

    CPC分类号： A61K9/0014 ,  A61K31/57 ,  A61K9/06 ,  Y10S514/943 ,  Y10S514/969

    摘要： An oil-in-water type cream comprising(a) 0.01 to 0.5% by weight of hydrocortisone butyrate proponate,(b) 5 to 50% by weight of a higher paraffinic hydrocarbon,(c) 3 to 15% by weight of a surface-active agent,(d) 30 to 65% by weight of purified water,(e) not more than 20% by weight of a monohydric higher alcohol,(f) not more than 20% by weight of a dihdyric or trihydric alcohol, and(g) a pharmaceutically acceptable acid in an amount required to adjust the pH of the cream to a value in the range of 3.5 to 6.5 when it is diluted with water to 20 times its volume.

    摘要翻译： 一种水包油型乳膏，其包含（a）0.01至0.5重量％的丙酸氢化可的松酸氢可的松，（b）5至50重量％的较高链烷烃，（c）3至15重量％的表面 活性剂，（d）30〜65重量％的纯水，（e）20重量％以下的一元高级醇，（f）20重量％以下的二羟基或三元醇， 和（g）当将其用水稀释至其体积的20倍时，将膏体的pH调节至3.5至6.5范围内所需的量的药学上可接受的酸。

    Continuous production of foam molding from expanded polyolefine resin beads
    6.
    发明申请
    Continuous production of foam molding from expanded polyolefine resin beads 审中-公开
    从膨胀聚烯烃树脂珠连续生产泡沫塑料

    公开(公告)号：US20050215652A1

    公开(公告)日：2005-09-29

    申请号：US11085541

    申请日：2005-03-22

    申请人： Masanori Tanaka ,  Kenji Tsunoda

    发明人： Masanori Tanaka ,  Kenji Tsunoda

    IPC分类号： B29C44/30 ,  B29C44/44 ,  C08J9/232 ,  C08J9/18

    CPC分类号： C08J9/232 ,  C08J2323/02

    摘要： A process for continuously preparing a polyolefin foam molding, wherein expanded polyolefin resin beads are fed between a pair of upper and lower endless belts continuously traveling along a pair of opposing upper and lower surfaces, respectively, within a passage defined by structural members and rectangular in section, the expanded beads feed being then successively passed through a heating zone and a cooling zone within the passage. The expanded polyolefin resin beads have a core-coat structure in which the core is in an expanded state and comprises a crystalline polyolefin resin, while the coat is in a substantially unexpanded state and surrounds the core. The coat comprises a crystalline polyolefin polymer which is lower in melting point by at least 15° C. than that of the crystalline polyolefin resin or a substantially non-crystalline polyolefin polymer which is lower in Vicat softening point by at least 15° C. than that of the crystalline polyolefin resin.

    摘要翻译： 一种用于连续制备聚烯烃发泡成型体的方法，其中发泡聚烯烃树脂珠粒分别在由结构构件限定的通道和矩形的通道内分别沿着一对相对的上表面和下表面连续行进的一对上下环形带之间进给 然后将膨胀的珠粒进料依次通过加热区和通道内的冷却区。 发泡聚烯烃树脂珠粒具有核心层，其中核心处于膨胀状态并且包含结晶聚烯烃树脂，而涂层处于基本上未膨胀的状态并且包围芯体。 该涂层包括结晶聚烯烃聚合物，其熔点低于结晶聚烯烃树脂或维卡软化点低至少15℃的基本上非结晶的聚烯烃聚合物至少15℃以上 结晶聚烯烃树脂。

    Semifinished joint plate, joint plate, process for fabricating joint plate and heat exchanger
    8.
    发明授权
    Semifinished joint plate, joint plate, process for fabricating joint plate and heat exchanger 有权
    半成品接头板，接头板，接头板和热交换器的制造工艺

    公开(公告)号：US07673670B2

    公开(公告)日：2010-03-09

    申请号：US10583375

    申请日：2005-03-08

    申请人： Naohisa Higashiyama ,  Kenji Tsunoda

    发明人： Naohisa Higashiyama ,  Kenji Tsunoda

    IPC分类号： F28D1/053

    CPC分类号： F28D1/05391 ,  F25B39/022 ,  F25B2500/01 ,  F28F9/0204 ,  F28F9/0214 ,  F28F9/0246 ,  F28F2220/00 ,  Y10T29/49393

    摘要： A semifinished joint plate 60 has a refrigerant inlet portion 45 and a refrigerant outlet portion 46 spaced apart in the front-rear direction. The semifinished plate 60 has an upwardly or downwardly extending slit 61 formed between the inlet portion 45 and the outlet portion 46, and slit width adjusting portions 62, 63 extending through the thickness of the plate 60, having a larger width than the slit 61 and communicating respectively with the upper and lower ends of the slit 61. A portion of the semifinished plate 60 above the upper adjusting portion 62 and a portion thereof below the lower adjusting portion 63 are bent to shorten the plate.

    摘要翻译： 半成品接头板60具有沿前后方向隔开的制冷剂入口部45和制冷剂出口部46。 半成品板60具有在入口部分45和出口部分46之间形成的向上或向下延伸的狭缝61，以及延伸穿过板60的厚度的狭缝宽度调节部分62,63，其宽度大于狭缝61和 与狭缝61的上端和下端分别连通。上调整部分62上方的半成品板60的一部分和下调整部分63下方的一部分被弯曲以缩短板。

    Semifinished Joint Plate, Joint Plate, Process for Fabricating Joint Plate and Heat Exchanger
    9.
    发明申请
    Semifinished Joint Plate, Joint Plate, Process for Fabricating Joint Plate and Heat Exchanger 有权
    半成品接头板，接头板，接头板和换热器的制造工艺

    公开(公告)号：US20070215331A1

    公开(公告)日：2007-09-20

    申请号：US10583375

    申请日：2005-03-08

    申请人： Naohisa Higashiyama ,  Kenji Tsunoda

    发明人： Naohisa Higashiyama ,  Kenji Tsunoda

    IPC分类号： F28F3/06 ,  B60H1/00

    CPC分类号： F28D1/05391 ,  F25B39/022 ,  F25B2500/01 ,  F28F9/0204 ,  F28F9/0214 ,  F28F9/0246 ,  F28F2220/00 ,  Y10T29/49393

    摘要： A semifinished joint plate 60 has a refrigerant inlet portion 45 and a refrigerant outlet portion 46 spaced apart in the front-rear direction. The semifinished plate 60 has an upwardly or downwardly extending slit 61 formed between the inlet portion 45 and the outlet portion 46, and slit width adjusting portions 62, 63 extending through the thickness of the plate 60, having a larger width than the slit 61 and communicating respectively with the upper and lower ends of the slit 61. A portion of the semifinished plate 60 above the upper adjusting portion 62 and a portion thereof below the lower adjusting portion 63 are bent to shorten the plate

    摘要翻译： 半成品接头板60具有沿前后方向隔开的制冷剂入口部45和制冷剂出口部46。 半成品板60具有在入口部分45和出口部分46之间形成的向上或向下延伸的狭缝61，以及延伸穿过板60的厚度的狭缝宽度调节部分62,63，其宽度大于狭缝61和 与狭缝61的上端和下端分别连通。上调整部分62上方的半成品板60的一部分和下调节部分63下方的一部分被弯曲以缩短板

    Mineral water
    10.
    发明授权
    Mineral water 失效
    矿泉水

    公开(公告)号：US5824353A

    公开(公告)日：1998-10-20

    申请号：US849862

    申请日：1997-06-10

    申请人： Kenji Tsunoda ,  Kazumi Osada

    发明人： Kenji Tsunoda ,  Kazumi Osada

    IPC分类号： C01B5/00 ,  C02F1/00 ,  C02F1/68 ,  A23L2/00

    CPC分类号： C02F1/005 ,  C02F1/68

    摘要： The cluster water having a potassium ion concentration of 100 ppm or more and containing potassium ions, magnesium ions and calcium ions in a weight ratio of potassium ions:magnesium ions:calcium ions of 1:0.3-4.5:0.5-8.5 has small clusters on the average, which are retained stably for a very long period of time at ordinary temperature.

    摘要翻译： PCT No.PCT / JP96 / 00018 Sec。 371日期：1997年6月10日 102（e）日期1997年6月10日PCT提交1996年1月10日PCT公布。 出版物WO96 / 21622 日期：1996年7月18日钾离子浓度为100ppm以上且含有钾离子：镁离子：钙离子为1：0.3〜4.5：0.5〜 8.5平均具有小簇，在常温下长时间保持稳定。