公开(公告)号：US20240268721A1

公开(公告)日：2024-08-15

申请号：US18626074

申请日：2024-04-03

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Akhil Srinivasan ,  Patrick W. Kinzie ,  Randal C. Schulhauser ,  Jennifer L. Marckmann ,  Mohsen Askarinya ,  James K. Carney ,  David L. Probst ,  Santhisagar Vaddiraju ,  Alejo Chavez Gaxiola ,  Richard J. O'Brien ,  Anna M. Tycon ,  Omid Mahdavi ,  Shawn C. Kelley ,  David A. Anderson

IPC: A61B5/1468 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1486 ,  G01N27/30 ,  G01N27/327

CPC classification number: A61B5/1468 ,  A61B5/053 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1486 ,  G01N27/301 ,  G01N27/3271

Abstract: Techniques are disclosed for measuring an analyte in a biological system. A system may include a medical device with an electrochemical sensor configured to sense the concentration of a plurality of analytes present in a biological system. Processing circuitry of the system may retrieve, identify, and process a respective signal from a respective work electrode to determine the concentration of a respective analyte. The system may further include an implantable medical device configured to sense a cardiac electrogram (EGM). In some examples, the system may be configured to determine one or more patient-specific relationships between the respective signals of the electrochemical sensor and the cardiac EGM during a first period of time. Based on the patient-specific relationships, the system may estimate concentrations of the one or more analytes corresponding to the respective signals based on the cardiac EGM of the patient collected over a second period of time.