公开(公告)号：US20230404446A1

公开(公告)日：2023-12-21

申请号：US18460271

申请日：2023-09-01

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Mohsen Askarinya ,  James K. Carney ,  Patrick W. Kinzie ,  Jennifer Lorenz Marckmann ,  Randal C. Schulhauser ,  Santhisagar Vaddiraju ,  Akhil Srinivasan ,  David Probst ,  Alejo Chavez Gaxiola

IPC: A61B5/1468 ,  A61B5/053 ,  A61B5/145

CPC classification number: A61B5/1468 ,  A61B5/053 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1486

Abstract: A biocompatible medical device may include an electrochemical sensor including a common reference electrode; at least one counter electrode; and a work electrode platform comprising a plurality of respective work electrodes, each respective work electrode electrically coupled to the common reference electrode and comprising a respective reagent substrate configured to react with a respective analyte to produce a respective signal indicative of a concentration of the respective analyte; and processing circuitry operatively coupled to the electrochemical sensor, and configured to receive from the electrochemical sensor a plurality of signals from the plurality of respective work electrodes; identify the respective signal corresponding to a respective selected work electrode; and process the identified signal to determine the concentration of the respective analyte associated with the respective selected work electrode.

公开(公告)号：US20200072782A1

公开(公告)日：2020-03-05

申请号：US16116306

申请日：2018-08-29

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Mohsen Askarinya ,  James K. Carney ,  Patrick W. Kinzie ,  Jennifer Lorenz Marckmann ,  Randal C. Schulhauser ,  Santhisagar Vaddiraju ,  Akhil Srinivasan ,  David Probst ,  Alejo Chavez Gaxiola

IPC: G01N27/327

Abstract: An electrochemical sensor may include a common reference electrode, at least one counter electrode, and a work electrode platform including a plurality of respective work electrodes. Each respective work electrode of the plurality of respective work electrodes may be electrically coupled to the common reference electrode and include a respective reagent substrate configured to react with a respective analyte to produce a signal indicative of a concentration of the respective analyte.

公开(公告)号：US10852268B2

公开(公告)日：2020-12-01

申请号：US16116306

申请日：2018-08-29

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Mohsen Askarinya ,  James K. Carney ,  Patrick W. Kinzie ,  Jennifer Lorenz Marckmann ,  Randal C. Schulhauser ,  Santhisagar Vaddiraju ,  Akhil Srinivasan ,  David Probst ,  Alejo Chavez Gaxiola

IPC: G01N27/327 ,  G01N33/483

Abstract: An electrochemical sensor may include a common reference electrode, at least one counter electrode, and a work electrode platform including a plurality of respective work electrodes. Each respective work electrode of the plurality of respective work electrodes may be electrically coupled to the common reference electrode and include a respective reagent substrate configured to react with a respective analyte to produce a signal indicative of a concentration of the respective analyte.

公开(公告)号：US20200069226A1

公开(公告)日：2020-03-05

申请号：US16116346

申请日：2018-08-29

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Mohsen Askarinya ,  James K. Carney ,  Patrick W. Kinzie ,  Jennifer Lorenz Marckmann ,  Randal C. Schulhauser ,  Santhisagar Vaddiraju ,  Akhil Srinivasan ,  David Probst ,  Alejo Chavez Gaxiola

IPC: A61B5/1468 ,  A61B5/145 ,  A61B5/053

Abstract: A biocompatible medical device may include an electrochemical sensor including a common reference electrode; at least one counter electrode; and a work electrode platform comprising a plurality of respective work electrodes, each respective work electrode electrically coupled to the common reference electrode and comprising a respective reagent substrate configured to react with a respective analyte to produce a respective signal indicative of a concentration of the respective analyte; and processing circuitry operatively coupled to the electrochemical sensor, and configured to receive from the electrochemical sensor a plurality of signals from the plurality of respective work electrodes; identify the respective signal corresponding to a respective selected work electrode; and process the identified signal to determine the concentration of the respective analyte associated with the respective selected work electrode.

公开(公告)号：US20240268721A1

公开(公告)日：2024-08-15

申请号：US18626074

申请日：2024-04-03

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Akhil Srinivasan ,  Patrick W. Kinzie ,  Randal C. Schulhauser ,  Jennifer L. Marckmann ,  Mohsen Askarinya ,  James K. Carney ,  David L. Probst ,  Santhisagar Vaddiraju ,  Alejo Chavez Gaxiola ,  Richard J. O'Brien ,  Anna M. Tycon ,  Omid Mahdavi ,  Shawn C. Kelley ,  David A. Anderson

IPC: A61B5/1468 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1486 ,  G01N27/30 ,  G01N27/327

CPC classification number: A61B5/1468 ,  A61B5/053 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1486 ,  G01N27/301 ,  G01N27/3271

Abstract: Techniques are disclosed for measuring an analyte in a biological system. A system may include a medical device with an electrochemical sensor configured to sense the concentration of a plurality of analytes present in a biological system. Processing circuitry of the system may retrieve, identify, and process a respective signal from a respective work electrode to determine the concentration of a respective analyte. The system may further include an implantable medical device configured to sense a cardiac electrogram (EGM). In some examples, the system may be configured to determine one or more patient-specific relationships between the respective signals of the electrochemical sensor and the cardiac EGM during a first period of time. Based on the patient-specific relationships, the system may estimate concentrations of the one or more analytes corresponding to the respective signals based on the cardiac EGM of the patient collected over a second period of time.

公开(公告)号：US12138050B2

公开(公告)日：2024-11-12

申请号：US18460271

申请日：2023-09-01

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Mohsen Askarinya ,  James K. Carney ,  Patrick W. Kinzie ,  Jennifer Lorenz Marckmann ,  Randal C. Schulhauser ,  Santhisagar Vaddiraju ,  Akhil Srinivasan ,  David Probst ,  Alejo Chavez Gaxiola

IPC: A61B5/1468 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1486 ,  G01N27/30 ,  G01N27/327

Abstract: A biocompatible medical device may include an electrochemical sensor including a common reference electrode; at least one counter electrode; and a work electrode platform comprising a plurality of respective work electrodes, each respective work electrode electrically coupled to the common reference electrode and comprising a respective reagent substrate configured to react with a respective analyte to produce a respective signal indicative of a concentration of the respective analyte; and processing circuitry operatively coupled to the electrochemical sensor, and configured to receive from the electrochemical sensor a plurality of signals from the plurality of respective work electrodes; identify the respective signal corresponding to a respective selected work electrode; and process the identified signal to determine the concentration of the respective analyte associated with the respective selected work electrode.

公开(公告)号：US11744492B2

公开(公告)日：2023-09-05

申请号：US16116346

申请日：2018-08-29

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Mohsen Askarinya ,  James K. Carney ,  Patrick W. Kinzie ,  Jennifer Lorenz Marckmann ,  Randal C. Schulhauser ,  Santhisagar Vaddiraju ,  Akhil Srinivasan ,  David Probst ,  Alejo Chavez Gaxiola

IPC: A61B5/1468 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1486 ,  G01N27/30 ,  G01N27/327

CPC classification number: A61B5/1468 ,  A61B5/053 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1486 ,  G01N27/301 ,  G01N27/3271

Abstract: A biocompatible medical device may include an electrochemical sensor including a common reference electrode; at least one counter electrode; and a work electrode platform comprising a plurality of respective work electrodes, each respective work electrode electrically coupled to the common reference electrode and comprising a respective reagent substrate configured to react with a respective analyte to produce a respective signal indicative of a concentration of the respective analyte; and processing circuitry operatively coupled to the electrochemical sensor, and configured to receive from the electrochemical sensor a plurality of signals from the plurality of respective work electrodes; identify the respective signal corresponding to a respective selected work electrode; and process the identified signal to determine the concentration of the respective analyte associated with the respective selected work electrode.