公开(公告)号：US10226630B2

公开(公告)日：2019-03-12

申请号：US15005533

申请日：2016-01-25

Applicant: Medtronic, Inc.

Inventor： Saul E Greenhut ,  Robert T Taepke ,  David R Bloem ,  Yong K Cho ,  Donna M Salmi

IPC: A61B5/02 ,  A61N1/365 ,  A61B5/0215 ,  A61B5/024 ,  A61B5/00 ,  A61M5/142 ,  A61M5/172 ,  A61N1/39 ,  A61B5/042 ,  A61N1/372

Abstract: Various techniques for measuring cardiac cycle length and pressure metrics based on pulmonary artery pressures are described. One example method described includes identifying a point within a derivative signal of a cardiovascular pressure signal without reference to electrical activity of a heart, initiating a time window from the identified point in the derivative signal, identifying a point within the cardiovascular signal within the time window, and determining at least one of a systolic pressure or diastolic pressure based on the identified point.

公开(公告)号：US09072914B2

公开(公告)日：2015-07-07

申请号：US14178711

申请日：2014-02-12

Applicant: Medtronic, Inc.

Inventor： Saul E Greenhut ,  Robert J Nehls ,  Walter H Olson ,  Xusheng Zhang ,  Wade M Demmer ,  Troy E Jackson ,  James D Reinke

IPC: A61N1/00 ,  A61N1/39 ,  A61N1/372 ,  A61N1/375 ,  A61N1/362

CPC classification number: A61N1/3962 ,  A61N1/056 ,  A61N1/3621 ,  A61N1/36585 ,  A61N1/37288 ,  A61N1/3756 ,  A61N1/3987

Abstract: Techniques and systems for monitoring cardiac arrhythmias and delivering electrical stimulation therapy using a subcutaneous implantable cardioverter defibrillator (SICD) and a leadless pacing device (LPD) are described. For example, the SICD may detect a tachyarrhythmia within a first electrical signal from a heart and determine, based on the tachyarrhythmia, to deliver anti-tachyarrhythmia shock therapy to the patient to treat the detected arrhythmia. The LPD may receive communication from the SICD requesting the LPD deliver anti-tachycardia pacing to the heart and determine, based on a second electrical signal from the heart sensed by the LPD, whether to deliver anti-tachycardia pacing (ATP) to the heart. In this manner, the SICD and LPD may communicate to coordinate ATP and/or cardioversion/defibrillation therapy. In another example, the LPD may be configured to deliver post-shock pacing after detecting delivery of anti-tachyarrhythmia shock therapy.

Abstract translation: 描述了使用皮下植入式心律转复除颤器（SICD）和无引线起搏装置（LPD）监测心律不齐和递送电刺激治疗的技术和系统。 例如，SICD可以检测来自心脏的第一电信号内的快速性心律失常，并且基于快速性心律失常确定将抗心律失常休克疗法递送给患者以治疗所检测到的心律失常。 LPD可以接收来自SICD的通信，请求LPD向心脏提供抗心动过速起搏，并且基于由LPD感测到的心脏的第二电信号确定是否将心动过速（ATP）提供给心脏。 以这种方式，SICD和LPD可以通信以协调ATP和/或心脏复律/除颤疗法。 在另一个示例中，LPD可以被配置为在检测到抗快速性心律失常性休克疗法的递送之后递送后冲击起搏。

公开(公告)号：US10004906B2

公开(公告)日：2018-06-26

申请号：US14801049

申请日：2015-07-16

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Juan Du ,  Saul E Greenhut ,  Michael T Hemming

IPC: A61B5/00 ,  A61N1/368 ,  A61B5/0452 ,  A61N1/375 ,  A61N1/365 ,  A61B5/042 ,  A61N1/362

CPC classification number: A61N1/3682 ,  A61B5/0422 ,  A61B5/0452 ,  A61B5/04525 ,  A61B5/7246 ,  A61B5/7285 ,  A61N1/3627 ,  A61N1/36507 ,  A61N1/3756

Abstract: A medical device and medical device system for controlling delivery of therapeutic stimulation pulses that includes a sensing device to sense a cardiac signal and emit a trigger signal in response to the sensed cardiac signal, a therapy delivery device to receive the trigger signal and deliver therapy to the patient in response to the emitted trigger signal, and a processor positioned within the sensing device, the processor configured to determine whether the sensed cardiac signal exceeds a possible P-wave threshold, compare a portion of the sensed cardiac signal to a P-wave template having a sensing window having a length less than a width of the P-wave, confirm an occurrence of a P-wave signal in response to the comparing, emit the trigger signal in response to the occurrence of a P-wave signal being confirmed, and inhibit delivery of the emitting signal in response to the occurrence of a P-wave signal not being confirmed.

公开(公告)号：US09775559B2

公开(公告)日：2017-10-03

申请号：US14253408

申请日：2014-04-15

Applicant: Medtronic, Inc.

Inventor： Xusheng Zhang ,  Mark L Brown ,  Saul E Greenhut ,  Robert W Stadler

IPC: A61B5/00 ,  A61B5/04 ,  A61B5/0464 ,  A61N1/37 ,  A61N1/38 ,  A61N1/372 ,  A61N1/362 ,  A61N1/39

CPC classification number: A61B5/4836 ,  A61B5/04012 ,  A61B5/0464 ,  A61B5/7246 ,  A61N1/3621 ,  A61N1/3702 ,  A61N1/37264 ,  A61N1/37282 ,  A61N1/385 ,  A61N1/39

Abstract: A medical device and associated method for detecting and treating tachyarrhythmias acquires a cardiac signal using electrodes coupled to a sensing module. During an initial detection process, a shockable cardiac rhythm is detected by a processing module configured to compare the cardiac signal to a first set of detection criteria. By analyzing the cardiac signal, the processing module establishes at least one patient-specific detection threshold during the initial detection process. Upon establishing the at least one patient-specific detection threshold, the initial detection process is stopped, and a next detection process is started which includes comparing the cardiac signal to a second set of detection criteria including the at least one patient-specific detection threshold. In some embodiments, user programming of tachyarrhythmia detection parameters is not required.

公开(公告)号：US09687654B2

公开(公告)日：2017-06-27

申请号：US14694279

申请日：2015-04-23

Applicant: Medtronic, Inc.

Inventor： Todd J Sheldon ,  James K Carney ,  Saul E Greenhut

IPC: A61N1/00 ,  A61N1/365 ,  A61N1/375 ,  A61N1/362 ,  A61N1/368 ,  A61N1/37

CPC classification number: A61N1/365 ,  A61N1/3627 ,  A61N1/368 ,  A61N1/3684 ,  A61N1/3712 ,  A61N1/3756

Abstract: An implantable medical device system including an atrial pacemaker and a ventricular pacemaker is configured to deliver dual chamber pacing in the presence of atrioventricular block. In response to detecting the AV block, the atrial pacemaker may establish a limited number of selectable pacing rates. The atrial pacemaker selects a rate from the limited number of selectable pacing rates and adjusts the atrial pacing rate to the selected rate. The ventricular pacemaker is configured to establish a ventricular pacing rate that is equivalent to the selected rate in response to detecting the AV block. Other examples are described herein.

公开(公告)号：US10441796B2

公开(公告)日：2019-10-15

申请号：US14644878

申请日：2015-03-11

Applicant: Medtronic, Inc.

Inventor： Wade M Demmer ,  Todd J Sheldon ,  Saul E Greenhut ,  James D Reinke

IPC: A61N1/37 ,  A61N1/362 ,  A61N1/365 ,  A61N1/375 ,  A61N1/36 ,  A61B5/00 ,  A61B5/0464 ,  A61N1/372 ,  A61B5/0402

Abstract: The control module of a first pacemaker included in an implantable medical device system including the first pacemaker and a second pacemaker is configured to set a pacing escape interval in response to a far field pacing pulse sensed by the first pacemaker. The far field pacing pulse is a pacing pulse delivered by the second pacemaker. The pacing escape interval is allowed to continue without restarting the in response to a far field intrinsic event sensed by the first pacemaker during the pacing escape interval. The first pacemaker delivers a cardiac pacing pulse to the heart upon expiration of the pacing escape interval.

公开(公告)号：US10278601B2

公开(公告)日：2019-05-07

申请号：US14260408

申请日：2014-04-24

Applicant: Medtronic, Inc.

Inventor： Saul E Greenhut ,  Robert W Stadler ,  Xusheng Zhang

IPC: A61B5/05 ,  A61B5/04 ,  A61B5/0408 ,  A61B5/0464 ,  A61B5/0472 ,  A61N1/00

Abstract: A method and medical device for determining sensing vectors that includes sensing cardiac signals from a plurality of electrodes, the plurality of electrodes forming a plurality of sensing vectors, determining signal differences during a detection window in each of the plurality of sensing vectors, ranking sensing vectors of the plurality of sensing vectors in response to the determined signal differences, and selecting one or more sensing vectors of the plurality of sensing vectors in response to the determined rankings.

公开(公告)号：US09795312B2

公开(公告)日：2017-10-24

申请号：US14340189

申请日：2014-07-24

Applicant: Medtronic, Inc.

Inventor： Saul E Greenhut ,  Robert W Stadler ,  Xusheng Zhang

IPC: A61B5/04 ,  A61B5/0408 ,  A61B5/042 ,  A61B5/0456

CPC classification number: A61B5/04011 ,  A61B5/0408 ,  A61B5/042 ,  A61B5/0456

Abstract: A method and medical device for determining sensing vectors that includes sensing cardiac signals from a plurality of electrodes, the plurality of electrodes forming a plurality of sensing vectors, setting a blanking period and a blanking period adjustment window for the plurality of sensing vectors in response to the sensed cardiac signals, determining first signal differences during the blanking period adjustment window, and adjusting the blanking period in response to the determined first signal differences.

公开(公告)号：US20140214104A1

公开(公告)日：2014-07-31

申请号：US14178711

申请日：2014-02-12

Applicant: Medtronic, Inc.

Inventor： Saul E Greenhut ,  Robert J Nehls ,  Walter H Olson ,  Xusheng Zhang ,  Wade M Demmer ,  Troy E Jackson ,  James D Reinke

IPC: A61N1/39 ,  A61N1/362 ,  A61N1/372

CPC classification number: A61N1/3962 ,  A61N1/056 ,  A61N1/3621 ,  A61N1/36585 ,  A61N1/37288 ,  A61N1/3756 ,  A61N1/3987

Abstract: Techniques and systems for monitoring cardiac arrhythmias and delivering electrical stimulation therapy using a subcutaneous implantable cardioverter defibrillator (SICD) and a leadless pacing device (LPD) are described. For example, the SICD may detect a tachyarrhythmia within a first electrical signal from a heart and determine, based on the tachyarrhythmia, to deliver anti-tachyarrhythmia shock therapy to the patient to treat the detected arrhythmia. The LPD may receive communication from the SICD requesting the LPD deliver anti-tachycardia pacing to the heart and determine, based on a second electrical signal from the heart sensed by the LPD, whether to deliver anti-tachycardia pacing (ATP) to the heart. In this manner, the SICD and LPD may communicate to coordinate ATP and/or cardioversion/defibrillation therapy. In another example, the LPD may be configured to deliver post-shock pacing after detecting delivery of anti-tachyarrhythmia shock therapy.

Abstract translation: 描述了使用皮下植入式心律转复除颤器（SICD）和无引线起搏装置（LPD）监测心律不齐和递送电刺激治疗的技术和系统。 例如，SICD可以检测来自心脏的第一电信号内的快速性心律失常，并且基于快速性心律失常确定将抗心律失常休克疗法递送给患者以治疗所检测到的心律失常。 LPD可以接收来自SICD的通信，请求LPD向心脏提供抗心动过速起搏，并且基于由LPD感测到的心脏的第二电信号确定是否将心动过速（ATP）提供给心脏。 以这种方式，SICD和LPD可以通信以协调ATP和/或心脏复律/除颤疗法。 在另一个示例中，LPD可以被配置为在检测到抗快速性心律失常性休克疗法的递送之后递送后冲击起搏。

公开(公告)号：US10252067B2

公开(公告)日：2019-04-09

申请号：US14487248

申请日：2014-09-16

Applicant: Medtronic, Inc.

Inventor： Saul E Greenhut ,  Robert W Stadler ,  Xusheng Zhang

IPC: A61N1/39 ,  A61B5/0456 ,  A61B5/0464 ,  A61N1/37 ,  A61B5/00

Abstract: A method and medical device for adjusting a blanking period that includes sensing cardiac signals from a plurality of electrodes, the plurality of electrodes forming a plurality of sensing vectors, determining whether to adjust a blanking period during a first operating state, advancing from the first operating state to a second operating state in response to the sensed cardiac signals, determining, while in the second operating state, whether the blanking period was adjusted while in the first operating state, and adjusting the blanking period while in the second operating state in response to the blanking period being adjusted while in the first operating state.