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公开(公告)号：US20210259760A1
公开(公告)日：2021-08-26
申请号：US17314894
申请日：2021-05-07
发明人： Sowmya Ballakur , Robert J. Beetel , Paul Friedrichs , David Herzfeld , Andrew Wu , Denise Zarins , Mark S. Leung
摘要： The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.
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2.发明申请Devices, Systems and Methods for Evaluation and Feedback of Neuromodulation Treatment 审中-公开用于评估和反馈神经调节治疗的装置，系统和方法公开(公告)号：US20150257815A1
公开(公告)日：2015-09-17
申请号：US14718843
申请日：2015-05-21
发明人： Sowmya Ballakur , Robert J. Beetel , Paul Friedrichs , David Herzfeld , Andrew Wu , Denise Zarins , Mark S. Leung
CPC分类号： A61B18/1206 , A61B18/10 , A61B18/1492 , A61B2017/00075 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00672 , A61B2018/00678 , A61B2018/00702 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00863 , A61B2018/00875 , A61F7/12 , A61F2007/0093 , A61F2007/126
摘要： The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.
摘要翻译： 本公开涉及用于评估应用于患者组织的治疗成功的装置，系统和方法，例如用于神经调节与肾动脉相关的神经的射频消融治疗。 系统监视在治疗过程中产生的参数或值。 提供给运营商的反馈是基于监测值，并且涉及对完成的处理在技术上成功的可能性的评估。 在其他实施例中，可以评估在不完全处理过程中产生的参数或值（例如由于高温或高阻抗条件），以向操作者提供额外的指令或反馈。
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3.发明申请Catheter Apparatuses Having Expandable Mesh Structures for Renal Neuromodulation and Associated Systems and Methods 审中-公开具有用于肾脏神经调节和相关系统和方法的可扩展网状结构的导管器械公开(公告)号：US20150126997A1
公开(公告)日：2015-05-07
申请号：US14598508
申请日：2015-01-16
CPC分类号： A61B18/1492 , A61B18/082 , A61B18/24 , A61B2018/00029 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00642 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00779 , A61B2018/00791 , A61B2018/00875 , A61B2018/00886 , A61B2018/1861 , A61B2218/002 , A61N7/022 , A61N2007/003 , Y10T29/49826
摘要： Catheter apparatuses having expandable mesh structures and associated systems and methods for intravascular renal neuromodulation are disclosed herein. A catheter treatment device includes an expandable mesh structure configured to position an energy delivery element in contact with a renal artery via an intravascular path. The mesh structure can assume an expanded configuration for direct and/or indirect application of thermal and/or electrical energy to heat or otherwise electrically modulate neural fibers that contribute to renal function. A collapsed configuration may facilitate insertion and/or removal of the catheter or repositioning of the energy delivery element within the renal artery.
摘要翻译： 本文公开了具有可扩张网状结构的导管装置和用于血管内肾神经调节的相关系统和方法。 导管治疗装置包括可扩张网状结构，其构造成通过血管内路径将能量递送元件定位成与肾动脉接触。 网状结构可以采取扩展配置，用于直接和/或间接施加热和/或电能以加热或以其他方式电调节有助于肾功能的神经纤维。 折叠构型可以促进导管的插入和/或移除或能量递送元件在肾动脉内的重新定位。
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4.发明申请Devices, Systems and Methods for Evaluation and Feedback of Neuromodulation Treatment 有权用于评估和反馈神经调节治疗的装置，系统和方法公开(公告)号：US20170020597A1
公开(公告)日：2017-01-26
申请号：US15136109
申请日：2016-04-22
发明人： Sowmya Ballakur , Robert J. Beetel , Paul Friedrichs , David Herzfeld , Andrew Wu , Denise Zarins , Mark S. Leung
CPC分类号： A61B18/1206 , A61B18/10 , A61B18/1492 , A61B2017/00075 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00672 , A61B2018/00678 , A61B2018/00702 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00863 , A61B2018/00875 , A61F7/12 , A61F2007/0093 , A61F2007/126
摘要： The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.
摘要翻译： 本公开涉及用于评估应用于患者组织的治疗成功的装置，系统和方法，例如用于神经调节与肾动脉相关的神经的射频消融治疗。 系统监视在治疗过程中产生的参数或值。 提供给运营商的反馈是基于监测值，并且涉及对完成的处理在技术上成功的可能性的评估。 在其他实施例中，可以评估在不完全处理过程中产生的参数或值（例如由于高温或高阻抗条件），以向操作者提供额外的指令或反馈。
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公开(公告)号：US20190183560A1
公开(公告)日：2019-06-20
申请号：US16219856
申请日：2018-12-13
发明人： Sowmya Ballakur , Robert J. Beetel , Paul Friedrichs , David Herzfeld , Andrew Wu , Denise Zarins , Mark S. Leung
CPC分类号： A61B18/1206 , A61B18/10 , A61B18/1492 , A61B2017/00075 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00672 , A61B2018/00678 , A61B2018/00702 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00863 , A61B2018/00875 , A61F7/12 , A61F2007/0093 , A61F2007/126
摘要： The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.
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公开(公告)号：US10179020B2
公开(公告)日：2019-01-15
申请号：US15665787
申请日：2017-08-01
发明人： Sowmya Ballakur , Robert J. Beetel , Paul Friedrichs , David Herzfeld , Andrew Wu , Denise Zarins , Mark S. Leung
摘要： The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.
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公开(公告)号：US20180028256A1
公开(公告)日：2018-02-01
申请号：US15665787
申请日：2017-08-01
发明人： Sowmya Ballakur , Robert J. Beetel , Paul Friedrichs , David Herzfeld , Andrew Wu , Denise Zarins , Mark S. Leung
CPC分类号： A61B18/1206 , A61B18/10 , A61B18/1492 , A61B2017/00075 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00672 , A61B2018/00678 , A61B2018/00702 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00863 , A61B2018/00875 , A61F7/12 , A61F2007/0093 , A61F2007/126
摘要： The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.
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公开(公告)号：US09345530B2
公开(公告)日：2016-05-24
申请号：US14718843
申请日：2015-05-21
发明人： Sowmya Ballakur , Robert J. Beetel , Paul Friedrichs , David Herzfeld , Andrew Wu , Denise Zarins , Mark S. Leung
CPC分类号： A61B18/1206 , A61B18/10 , A61B18/1492 , A61B2017/00075 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00672 , A61B2018/00678 , A61B2018/00702 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00863 , A61B2018/00875 , A61F7/12 , A61F2007/0093 , A61F2007/126
摘要： The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.
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9.发明申请公开(公告)号：US20190269908A1
公开(公告)日：2019-09-05
申请号：US16291689
申请日：2019-03-04
发明人： Neil C. Barman , Robert J. Beetel , Benjamin J. Clark , Andrew Wu , Maria G. Aboytes , Denise Zarins
摘要： Catheter assemblies for neuromodulation proximate a renal artery bifurcation and associated systems and methods are disclosed herein. A catheter assembly configured in accordance with a particular embodiment of the present technology can include a shaft having a proximal portion, a distal portion, and two therapeutic arms extending from the distal portion. The shaft can be configured to deliver the distal portion to a treatment site proximate a branch point or bifurcation in a renal blood vessel. The therapeutic arms can include energy delivery elements that are configured to deliver the therapeutically-effective energy to renal nerves proximate the branch point.
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公开(公告)号：US20140276718A1
公开(公告)日：2014-09-18
申请号：US14203933
申请日：2014-03-11
IPC分类号： A61B18/08
CPC分类号： A61B18/082 , A61B2018/0016 , A61B2018/00184 , A61B2018/00214 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00702 , A61B2018/0072 , A61B2018/00791 , A61B2018/00886 , A61B2018/1435 , A61B2018/144 , A61B2018/1475
摘要： Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device including a therapeutic assembly having a central axis and a distal portion and a proximal portion axially spaced along the central axis, the therapeutic assembly including a core element extending from the proximal portion to the distal portion and a heating element disposed along at least a portion of a length of the core element. An energy source provides electrical current to the heating element to cause the heating element to increase in temperature.
摘要翻译： 本文公开了通过血管内通路实现肾脏神经调节的导管装置，系统和方法。 本技术的一个方面，例如涉及包括治疗组件的治疗装置，所述治疗组件具有中心轴线和远侧部分以及沿中心轴线轴向隔开的近端部分，所述治疗组件包括从所述近端 远端部分的一部分和沿着芯元件的长度的至少一部分设置的加热元件。 能量源向加热元件提供电流以使加热元件的温度升高。
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