公开(公告)号：US20230148916A1

公开(公告)日：2023-05-18

申请号：US17454751

申请日：2021-11-12

Applicant: Medtronic MiniMed, Inc.

Inventor： Sarkis D. Aroyan ,  Ellis Garai

IPC: A61B5/145 ,  A61M5/172 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61M5/1723 ,  A61B5/0004 ,  A61M2005/1726

Abstract: In some examples, a system for monitoring glucose includes processing circuitry and a glucose monitor comprising one or more monitor electrodes and one or more working electrodes, wherein a first chemistry stack is disposed on at least one of the monitor electrode(s) and a second chemistry stack is disposed on at least one of the working electrode(s). The processing circuitry may be configured to measure one or more calibration values of an operating parameter of the monitor electrode(s), retrieve one or more pre-calibration values of the operating parameter of the monitor electrode(s), wherein the pre-calibration value(s) were measured before the calibration value, determine one or more delta values using the calibration value(s) and the pre-calibration value(s), and calibrate glucose values sensed by the working electrode(s) using the delta value(s).

公开(公告)号：US20230404448A1

公开(公告)日：2023-12-21

申请号：US18136417

申请日：2023-04-19

Applicant: Medtronic MiniMed, Inc.

Inventor： Ellis Garai ,  Sarkis D. Aroyan ,  Anuj M. Patel ,  Ashwin K. Rao

IPC: A61B5/1495 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  A61B5/14865 ,  A61B2560/0276 ,  A61B5/7221 ,  A61B5/7203 ,  A61B5/4839

Abstract: A method for compensating for a life-lengthening agent for a glucose sensor includes accessing first and second electrochemical impedance spectroscopy (EIS) values of at least one parameter based on first and second EIS procedures performed on EIS signals from a working electrode of the glucose sensor, calculating a change in the at least one parameter between the first and second EIS values, estimating a concentration of the agent based on the change in the at least one parameter, and calculating a model effect in response to the concentration. In a case where the model effect is not greater than the threshold, the method further includes adjusting a sensor glucose value based on the concentration and sensor signals from the working electrode, and displaying the adjusted sensor glucose value.

公开(公告)号：US20230080129A1

公开(公告)日：2023-03-16

申请号：US17474921

申请日：2021-09-14

Applicant: Medtronic MiniMed, Inc.

Inventor： Ellis Garai ,  Sarkis D. Aroyan ,  Anuj M. Patel ,  Michael E. Miller

IPC: A61B5/145 ,  G01N27/04 ,  A61B5/1486

Abstract: A device for determining a glucose level of a patient includes a set of electrodes comprising a first working electrode, a second working electrode, a counter electrode, and a reference electrode. The reference electrode is electrically coupled to the counter electrode. The device further includes a memory and one or more processors implemented in circuitry and in communication with the memory. The one or more processors configured to determine a sensor signal based on current flowing between the first working electrode and the counter electrode and determine an open circuit potential (OCP) signal based on a voltage across the second working electrode and the reference electrode. The one or more processors are further configured to determine the glucose level of the patient based on the sensor signal and the OCP signal and output an indication of the glucose level.

公开(公告)号：US20230310341A1

公开(公告)日：2023-10-05

申请号：US18192479

申请日：2023-03-29

Applicant: Medtronic MiniMed, Inc.

Inventor： Ellis Garai ,  Ashwin K. Rao ,  Margaret R. Miller ,  Sarkis D. Aroyan

IPC: A61K9/70 ,  A61B5/145 ,  A61B5/00

CPC classification number: A61K9/7092 ,  A61B5/14532 ,  A61B5/6833 ,  A61B2560/0412

Abstract: The invention provides a skin adhesive patch that inhibits skin irritation by releasing an anti-inflammatory agent such as a corticosteroid topically on the skin surface. Embodiments of the invention can be adapted for use with a wide variety of adhesive patches that are used to couple medical components to the skin of patients such as the devices that diabetic patients use including insulin infusion sets, patch pumps, and all-in-one patch sets.

公开(公告)号：US20220395199A1

公开(公告)日：2022-12-15

申请号：US17345511

申请日：2021-06-11

Applicant: Medtronic MiniMed, Inc.

Inventor： Ellis Garai ,  Sarkis D. Aroyan ,  Margaret R. Miller ,  Melissa Tsang

IPC: A61B5/145 ,  A61B5/1468

Abstract: An example method for initializing a glucose sensor includes executing an initialization sequence for the glucose sensor, wherein the initialization sequence is based on one or more of parameters related to manufacturing the glucose sensor or environmental conditions of the glucose sensor that are present in vivo, and reporting glucose levels in a patient after the initialization sequence.

公开(公告)号：US20250160703A1

公开(公告)日：2025-05-22

申请号：US18934534

申请日：2024-11-01

Applicant: Medtronic MiniMed, Inc.

Inventor： Juan Enrique Arguelles Morales ,  Sadaf S. Seleh ,  Leonardo Nava-Guerra ,  Bahram B. Notghi ,  Georgios Mallas ,  Francesca Piccinini ,  Sarkis D. Aroyan ,  Ellis Garai ,  Zachary A. Shah

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/145

Abstract: A system for reducing sensor variability includes a sensor configured to generate real-time data relating to glucose sensitivity. The system causes performance of accessing the real-time data from the sensor relating to glucose sensitivity and inputting the real-time data into a machine learning model. The system also causes performance of estimating by the machine learning model an expected glucose sensitivity based on the real-time data and correcting the glucose sensitivity based on the expected glucose sensitivity.

公开(公告)号：US20230004815A1

公开(公告)日：2023-01-05

申请号：US17365803

申请日：2021-07-01

Applicant: Medtronic MiniMed, Inc.

Inventor： Elaine Gee ,  Francesca Piccinini ,  Li Zhou ,  Chi A Tran ,  Farhad Batmanghelich ,  Leonardo Nava-Guerra ,  Juan Enrique Arguelles Morales ,  Anuj M. Patel ,  Sarkis D. Aroyan

IPC: G06N3/08 ,  A61B5/145 ,  A61B5/00

Abstract: An example method for calibrating a glucose sensor includes determining, by one or more processors, a set of electrical parameters for the glucose sensor of a plurality of glucose sensors and determining, by the one or more processors, a cluster for the glucose sensor based on the set of electrical parameters. Each cluster of the plurality of clusters identifies respective configuration information. In this example, the method includes configuring, by the one or more processors, the glucose sensor to determine a glucose level of a patient based on configuration information identified by the determined cluster.