公开(公告)号：US12082910B2

公开(公告)日：2024-09-10

申请号：US16942721

申请日：2020-07-29

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Li Zhou ,  Raymond M. Russell ,  Peter Schultz ,  Anuj M. Patel ,  Carol Chen ,  Roshanne Malekmadani ,  Lynette To ,  Hsiao-Yu S. Kow ,  Raghavendhar Gautham

IPC: A61B5/00 ,  A61B5/145

CPC classification number: A61B5/0095 ,  A61B5/14532 ,  A61B5/7267

Abstract: Systems and methods are described herein for utilizing a photoacoustic sensor for estimating analyte concentration levels. Also described here are training methods for training an analyte sensor to more accurately estimate an analyte concentration level on the basis of a received acoustic signal.

公开(公告)号：US20190000358A1

公开(公告)日：2019-01-03

申请号：US15639116

申请日：2017-06-30

Applicant: Medtronic MiniMed, Inc.

Inventor： Anuj M. Patel

IPC: A61B5/145 ,  A61B5/1495 ,  A61B5/00

Abstract: A method of initializing a sensor with a voltage sequence including a ramped voltage combined with a biphasic voltage pulse. The initialization scheme results in faster in-vitro sensor run-in and stabilization times. In various examples, the in-vitro sensor stabilization time is reduced from 200 minutes to 40-55 minutes (a reduction by a factor of least 5 as compared to a non-initialized sensor). In addition, staircase voltage initialization is implemented adaptively so that the voltage step size and sweep rates are changed depending on the state of the sensor (characterized by ISIG magnitude). As a result, individual sensors can be initialized in a customized manner rather than by using a general hardwired and harsh initialization scheme.

公开(公告)号：US20230157598A1

公开(公告)日：2023-05-25

申请号：US17531294

申请日：2021-11-19

Applicant: Medtronic MiniMed, Inc.

Inventor： Davy Tong ,  Anuj M. Patel ,  Sarnath Chattaraj ,  Hsi Fusselman ,  Chia-Hung Chiu ,  Timothy Kwa ,  Nor Akmaliza Rais ,  Michael Weikai Chang ,  Vijaykumar Raorane

IPC: A61B5/1495 ,  G01N27/08 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1477 ,  A61B5/145 ,  A61B5/0537 ,  A61B5/1473

CPC classification number: A61B5/1495 ,  G01N27/08 ,  G01N27/026 ,  G01N33/49 ,  A61B5/1477 ,  A61B5/14532 ,  A61B5/0537 ,  A61B5/1473

Abstract: A method includes monitoring, via a device including an electrochemical cell, an electrical current that is proportional to an impedance of the electrochemical cell, and responsive to determining that the electrical current satisfies a threshold, measuring, via the device, a plurality of impedances of the electrochemical cell corresponding to a plurality of frequencies. The method further includes determining a charge transfer conductance and a solution resistance based on the plurality of impedances at fewer than four of the corresponding plurality of frequencies and determining the presence of electrochemical interference based on the solution resistance and the charge transfer conductance. The method further includes outputting an alert based on the determination of the presence of electrochemical interference.

公开(公告)号：US10856784B2

公开(公告)日：2020-12-08

申请号：US15639116

申请日：2017-06-30

Applicant: Medtronic MiniMed, Inc.

Inventor： Anuj M. Patel

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/00 ,  G01N27/327

Abstract: A method of initializing a sensor with a voltage sequence including a ramped voltage combined with a biphasic voltage pulse. The initialization scheme results in faster in-vitro sensor run-in and stabilization times. In various examples, the in-vitro sensor stabilization time is reduced from 200 minutes to 40-55 minutes (a reduction by a factor of least 5 as compared to a non-initialized sensor). In addition, staircase voltage initialization is implemented adaptively so that the voltage step size and sweep rates are changed depending on the state of the sensor (characterized by ISIG magnitude). As a result, individual sensors can be initialized in a customized manner rather than by using a general hardwired and harsh initialization scheme.

公开(公告)号：US20230004815A1

公开(公告)日：2023-01-05

申请号：US17365803

申请日：2021-07-01

Applicant: Medtronic MiniMed, Inc.

Inventor： Elaine Gee ,  Francesca Piccinini ,  Li Zhou ,  Chi A Tran ,  Farhad Batmanghelich ,  Leonardo Nava-Guerra ,  Juan Enrique Arguelles Morales ,  Anuj M. Patel ,  Sarkis D. Aroyan

IPC: G06N3/08 ,  A61B5/145 ,  A61B5/00

Abstract: An example method for calibrating a glucose sensor includes determining, by one or more processors, a set of electrical parameters for the glucose sensor of a plurality of glucose sensors and determining, by the one or more processors, a cluster for the glucose sensor based on the set of electrical parameters. Each cluster of the plurality of clusters identifies respective configuration information. In this example, the method includes configuring, by the one or more processors, the glucose sensor to determine a glucose level of a patient based on configuration information identified by the determined cluster.

公开(公告)号：US20220031205A1

公开(公告)日：2022-02-03

申请号：US16944450

申请日：2020-07-31

Applicant: Medtronic MiniMed, Inc.

Inventor： David Yueh-hua Choy ,  Ellis Garai ,  Melissa Tsang ,  Anuj M. Patel

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1495

Abstract: An analyte sensor apparatus including a sensing portion including one or more electrodes including a working electrode and one or more contacts for electrically connecting the sensor portion to control circuitry (e.g., a printed circuit board assembly, PCBA); and a circuit comprising the one or more contacts; wherein the circuit detects an electrical connection between the control circuitry without requiring exposure of the sensing portion to a fluid.

公开(公告)号：US12082924B2

公开(公告)日：2024-09-10

申请号：US16944450

申请日：2020-07-31

Applicant: Medtronic MiniMed, Inc.

Inventor： David Yueh-Hua Choy ,  Ellis Garai ,  Melissa Tsang ,  Anuj M. Patel

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1495

CPC classification number: A61B5/14532 ,  A61B5/1495 ,  A61B5/4839 ,  A61B2560/0214 ,  A61B2560/0223 ,  A61B2562/166 ,  A61B2562/227

Abstract: An analyte sensor apparatus including a sensing portion including one or more electrodes including a working electrode and one or more contacts for electrically connecting the sensor portion to control circuitry (e.g., a printed circuit board assembly, PCBA); and a circuit comprising the one or more contacts; wherein the circuit detects an electrical connection between the control circuitry without requiring exposure of the sensing portion to a fluid.

公开(公告)号：US20230404448A1

公开(公告)日：2023-12-21

申请号：US18136417

申请日：2023-04-19

Applicant: Medtronic MiniMed, Inc.

Inventor： Ellis Garai ,  Sarkis D. Aroyan ,  Anuj M. Patel ,  Ashwin K. Rao

IPC: A61B5/1495 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  A61B5/14865 ,  A61B2560/0276 ,  A61B5/7221 ,  A61B5/7203 ,  A61B5/4839

Abstract: A method for compensating for a life-lengthening agent for a glucose sensor includes accessing first and second electrochemical impedance spectroscopy (EIS) values of at least one parameter based on first and second EIS procedures performed on EIS signals from a working electrode of the glucose sensor, calculating a change in the at least one parameter between the first and second EIS values, estimating a concentration of the agent based on the change in the at least one parameter, and calculating a model effect in response to the concentration. In a case where the model effect is not greater than the threshold, the method further includes adjusting a sensor glucose value based on the concentration and sensor signals from the working electrode, and displaying the adjusted sensor glucose value.

公开(公告)号：US20230080129A1

公开(公告)日：2023-03-16

申请号：US17474921

申请日：2021-09-14

Applicant: Medtronic MiniMed, Inc.

Inventor： Ellis Garai ,  Sarkis D. Aroyan ,  Anuj M. Patel ,  Michael E. Miller

IPC: A61B5/145 ,  G01N27/04 ,  A61B5/1486

Abstract: A device for determining a glucose level of a patient includes a set of electrodes comprising a first working electrode, a second working electrode, a counter electrode, and a reference electrode. The reference electrode is electrically coupled to the counter electrode. The device further includes a memory and one or more processors implemented in circuitry and in communication with the memory. The one or more processors configured to determine a sensor signal based on current flowing between the first working electrode and the counter electrode and determine an open circuit potential (OCP) signal based on a voltage across the second working electrode and the reference electrode. The one or more processors are further configured to determine the glucose level of the patient based on the sensor signal and the OCP signal and output an indication of the glucose level.

公开(公告)号：US10575767B2

公开(公告)日：2020-03-03

申请号：US14726224

申请日：2015-05-29

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Anuj M. Patel ,  Zachary Decke ,  Bradley C. Liang

IPC: A61B5/1473 ,  A61B5/145 ,  A61M5/142 ,  A61B5/1486 ,  A61B5/00

Abstract: A method for monitoring an analyte within the body of a patient, an analyst sensor, and an analyte monitoring apparatus are presented here. In accordance with certain embodiments, the method for monitoring an analyte within the body of a patient includes implanting an analyte sensor at a sensor placement site in the patient. The analyte sensor includes a reference electrode, a counter electrode, a primary working electrode having a first structure, and an auxiliary working electrode having a second structure different from the first structure. The method includes communicating a primary signal from the primary working electrode and an auxiliary signal from the auxiliary working electrode to a processor. Further, the method includes monitoring the primary signal and the auxiliary signal with the processor to characterize a change in a physiological characteristic at the sensor placement site.