利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

9 条记录 (耗时 0.018 秒)

    Process of preparing alkylhydroxyalkylcellulose
    3.
    发明授权
    Process of preparing alkylhydroxyalkylcellulose 有权
    制备烷基羟烷基纤维素的方法

    公开(公告)号：US07402668B2

    公开(公告)日：2008-07-22

    申请号：US10197070

    申请日：2002-07-17

    申请人： Wolfgang Dannhorn ,  Erik-Andreas Klohr ,  Martin Kowollik ,  Hartwig Schlesiger ,  Jörn-Bernd Pannek

    发明人： Wolfgang Dannhorn ,  Erik-Andreas Klohr ,  Martin Kowollik ,  Hartwig Schlesiger ,  Jörn-Bernd Pannek

    IPC分类号： C07H1/00 ,  C08B11/08 ,  C08B11/02 ,  C08B1/00

    CPC分类号： C08B11/193

    摘要： A process of preparing alkylhydroxyalkylcellulose (e.g., methylhydroxyethylcellulose and methylhydroxypropylcellulose) by reaction of cellulose in the presence of alkali metal hydroxide with an alkylating agent and a hydroxyalkylating agent is described. The process includes: (a) alkalizing cellulose by means of 0.9 to 2.9 equivalents of an alkali metal hydroxide I/AGU of the cellulose in the form of an aqueous alkali metal hydroxide solution, in the presence of a suspension medium containing at least 0.2 equivalents of an alkylating agent I/AGU of the cellulose; (b) reacting the alkalized cellulose of step (a) with alkylating agent I and a hydroxyalkylating agent at a temperature above 65° C.; (c) adding additional alkali metal hydroxide 11 in the form of an aqueous alkali metal hydroxide solution; and (d) adding additional alkylating agent 11 in an amount of at least the absolute value of the difference between (i) the number of equivalents of alkylating agent I/AGU of the cellulose already added, and (ii) the total number of equivalents of alkali metal hydroxide/AGU of the cellulose added. Additional alkylating agent 11 is not added in step (d) if (i) the number of equivalents of alkylating agent I/AGU of the cellulose already added exceeds (ii) the total number of equivalents of alkali metal hydroxide/AGU of the cellulose already added. In a further step (e), the alkylhydroxyalkylcellulose is isolated from the reaction mixture. The isolated alkylhydroxyalkylcellulose may be optionally purified.

    摘要翻译： 描述了通过在碱金属氢氧化物存在下纤维素与烷基化剂和羟烷基化剂反应来制备烷基羟烷基纤维素（例如甲基羟乙基纤维素和甲基羟丙基纤维素）的方法。 该方法包括：（a）在含有至少0.2当量的悬浮介质存在下，通过0.9至2.9当量的碱金属氢氧化物I / AGU将纤维素碱化为碱金属氢氧化物水溶液形式的纤维素碱化纤维素 的纤维素的烷基化剂I / AGU; （b）在高于65℃的温度下使步骤（a）的碱化纤维素与烷基化剂I和羟烷基化剂反应; （c）加入碱金属氢氧化物水溶液形式的另外的碱金属氢氧化物11; 和（d）添加额外的烷基化剂11，其量至少为（i）已经加入的纤维素的烷基化剂I / AGU的当量数之间的差异的绝对值，和（ii）总当量数 的碱金属氢氧化物/ AGU的纤维素加入。 如果（i）已经加入的纤维素的烷基化剂I / AGU的当量数超过（ii）已经在纤维素中的碱金属氢氧化物/ AGU的当量的总数，则在步骤（d）中不加入另外的烷基化剂11 添加。 在另外的步骤（e）中，从反应混合物中分离烷基羟烷基纤维素。 分离的烷基羟烷基纤维素可以任选地纯化。

    Process for the production of methylhydroxyalkyl cellulose
    7.
    发明申请
    Process for the production of methylhydroxyalkyl cellulose 审中-公开
    生产甲基羟烷基纤维素的方法

    公开(公告)号：US20050240016A1

    公开(公告)日：2005-10-27

    申请号：US11105679

    申请日：2005-04-14

    申请人： Hartwig Schlesiger ,  Wolfgang Dannhorn ,  Erik-Andreas Klohr ,  Martin Kowollik ,  Marc Schmidt

    发明人： Hartwig Schlesiger ,  Wolfgang Dannhorn ,  Erik-Andreas Klohr ,  Martin Kowollik ,  Marc Schmidt

    IPC分类号： C08B11/193 ,  C08B11/02

    CPC分类号： C08B11/193

    摘要： A process of producing methylhydroxyalkyl cellulose (MHAC) is described and involves in a first step (a), (i) introducing cellulose and a suspension medium into an autoclave, the suspension medium comprising 20 wt. % to 50 wt. % of chloromethane, based on the total weight of the said suspension medium, and (ii) spraying the cellulose in the autoclave with an aqueous alkali metal hydroxide solution, thereby alkalizing the cellulose and reacting the cellulose with chloromethane. In a second step (b), hydroxyalkylating agent is optionally introduced into the autoclave at a temperature above 60° C. In a third step (c) alkali metal hydroxide is introduced into the autoclave in a hyperstoichiometric quantity of at least +0.1 mol eq., relative to the chloromethane utilised. In a fourth step (d), at least one hydroxyalkylating agent is optionally introduced into the autoclave at a temperature above 60° C., and the introduced hydroxyalkylating agent is allowed to react for at least 20 min. In a fifth step (e), additional chloromethane is introduced into the autoclave in a hyperstoichiometric quantity of at least +0.2 mol eq., relative to the total alkali metal hydroxide utilised up to this point. In a sixth step (f), additional alkali metal hydroxide is optionally introduced into the autoclave, and the reaction is allowed to continue at a temperature of from 60° C. to 110° C. Finally, the suspension medium is removed by means of distillation, thus forming a distillate comprising residual chloromethane, and the methylhydroxyalkyl cellulose is isolated. Optionally, the isolated methylhydroxyalkyl cellulose may be washed, and dried. The addition of hydroxyalkylating agent occurs in step (b) and/or step (d).

    摘要翻译： 描述了生产甲基羟烷基纤维素（MHAC）的方法，并涉及第一步（a），（i）将纤维素和悬浮介质引入高压釜中，所述悬浮介质包含20wt。 ％至50重量％ ％的氯甲烷，基于所述悬浮介质的总重量，和（ii）用碱金属氢氧化物水溶液在高压釜中喷涂纤维素，由此碱化纤维素并使纤维素与氯甲烷反应。 在第二步（b）中，任选地将羟烷基化试剂在高于60℃的温度下引入高压釜中。在第三步骤（c）中，将碱金属氢氧化物以高化学计量的至少+0.1mol当量 相对于所用的氯甲烷。 在第四步骤（d）中，任选地在高于60℃的温度下将至少一种羟烷基化剂引入高压釜中，使引入的羟烷基化剂反应至少20分钟。 在第五步（e）中，相对于直到此为止使用的总碱金属氢氧化物，额外的氯甲烷以至少+0.2mol当量的超化学计量量被引入高压釜中。 在第六步（f）中，任选地将另外的碱金属氢氧化物引入高压釜中，使反应在60℃至110℃的温度下继续。最后，通过 蒸馏，从而形成包含残余氯甲烷的馏出物，并分离甲基羟烷基纤维素。 任选地，分离的甲基羟烷基纤维素可以被洗涤并干燥。 羟化烷基化剂的添加发生在步骤（b）和/或步骤（d）中。