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公开(公告)号:US20070142373A1
公开(公告)日:2007-06-21
申请号:US10557079
申请日:2004-05-19
申请人: Ian Baldwin , Michael Barker , Anthony Dean , Colin Eldred , Brian Evans , Sharon Gough , Stephen Guntrip , Julie Hamblin , Stuart Holman , Paul Jones , Mika Lindvall , Christopher Lunniss , Tracy Redfern , Alison Redgrave , John Robinson , Michael Woodrow
发明人: Ian Baldwin , Michael Barker , Anthony Dean , Colin Eldred , Brian Evans , Sharon Gough , Stephen Guntrip , Julie Hamblin , Stuart Holman , Paul Jones , Mika Lindvall , Christopher Lunniss , Tracy Redfern , Alison Redgrave , John Robinson , Michael Woodrow
IPC分类号: A61K31/5377 , A61K31/496 , A61K31/4709 , C07D413/02 , C07D403/02 , C07D401/02
CPC分类号: C07D401/12 , C07D215/54 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D453/02
摘要: There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
摘要翻译: 根据本发明提供新的式(I)化合物或其药学上可接受的盐,其中R 1,R 2,R 19,R 20和R 34如说明书中所述,其制备方法,含有 他们及其在治疗炎症性疾病中的应用。
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公开(公告)号:US20060178416A1
公开(公告)日:2006-08-10
申请号:US11349677
申请日:2006-02-08
申请人: Michael Barker , Anthony Dean , Brian Evans , Stuart Holman , Michael Woodrow
发明人: Michael Barker , Anthony Dean , Brian Evans , Stuart Holman , Michael Woodrow
IPC分类号: A01N43/50
CPC分类号: C07D401/12 , C07D215/54 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D453/02
摘要: There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
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公开(公告)号:US20090312325A1
公开(公告)日:2009-12-17
申请号:US12474324
申请日:2009-05-29
申请人: Ian Robert Baldwin , Michael David Barker , Anthony William Dean , Colin David Eldred , Brian Evans , Sharon Lisa Gough , Stephen Barry Guntrip , Julie Nicole Hamblin , Stuart Holman , Paul Jones , Mika Kristian Lindvall , Christopher James Lunniss , Tracy Jane Redfern , Alison Judith Redgrave , John Edward Robinson , Michael Woodrow
发明人: Ian Robert Baldwin , Michael David Barker , Anthony William Dean , Colin David Eldred , Brian Evans , Sharon Lisa Gough , Stephen Barry Guntrip , Julie Nicole Hamblin , Stuart Holman , Paul Jones , Mika Kristian Lindvall , Christopher James Lunniss , Tracy Jane Redfern , Alison Judith Redgrave , John Edward Robinson , Michael Woodrow
IPC分类号: A61K31/4709 , C07D401/12 , C07D417/12 , C07D403/12 , C07D215/38 , A61K31/47 , A61K31/5377 , A61P29/00 , A61P37/08
CPC分类号: C07D401/12 , C07D215/54 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D453/02
摘要: There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
摘要翻译: 根据本发明提供新的式(I)化合物或其药学上可接受的盐,其中R1,R2,R19,R20和R34如说明书中所述,其制备方法,含有它们的制剂及其在 治疗炎症性疾病。
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公开(公告)号:US07572915B2
公开(公告)日:2009-08-11
申请号:US11349677
申请日:2006-02-08
IPC分类号: C07D215/38
CPC分类号: C07D401/12 , C07D215/54 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D453/02
摘要: There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
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公开(公告)号:US07566786B2
公开(公告)日:2009-07-28
申请号:US10557079
申请日:2004-05-19
申请人: Ian Robert Baldwin , Michael David Barker , Anthony William Dean , Colin David Eldred , Brian Evans , Sharon Lisa Gough , Stephen Barry Guntrip , Julie Nicole Hamblin , Stuart Holman , Paul Jones , Mika Kristian Lindvall , Christopher James Lunniss , Tracy Jane Redfern , Alison Judith Redgrave , John Edward Robinson , Michael Woodrow
发明人: Ian Robert Baldwin , Michael David Barker , Anthony William Dean , Colin David Eldred , Brian Evans , Sharon Lisa Gough , Stephen Barry Guntrip , Julie Nicole Hamblin , Stuart Holman , Paul Jones , Mika Kristian Lindvall , Christopher James Lunniss , Tracy Jane Redfern , Alison Judith Redgrave , John Edward Robinson , Michael Woodrow
IPC分类号: C07D215/38 , C07D215/44
CPC分类号: C07D401/12 , C07D215/54 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D453/02
摘要: There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
摘要翻译: 根据本发明提供新的式(I)化合物或其药学上可接受的盐,其中R1,R2,R19,R20和R34如说明书中所述,其制备方法,含有它们的制剂及其在 治疗炎症性疾病。
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公开(公告)号:US20070049570A1
公开(公告)日:2007-03-01
申请号:US11349701
申请日:2006-02-08
IPC分类号: A61K31/56
CPC分类号: C07D401/12 , C07D215/54 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D453/02
摘要: There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
摘要翻译: 根据本发明提供新的式(I)化合物或其药学上可接受的盐,其中R1,R2,R19,R20和R34如说明书中所述,其制备方法,含有它们的制剂及其在 治疗炎症性疾病。
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公开(公告)号:US20080090822A1
公开(公告)日:2008-04-17
申请号:US11908149
申请日:2006-03-09
申请人: Daniel Bradley , Clive Branch , Bethany Brown , Wai Chan , Steven Coulton , Martin Gilpin , Sharon Gough , Jacqueline MacRitchie , Howard Marshall , David Nash , Roderick Porter , Anthony Dean , Paul Doyle , Brian Evans , Luigi Stasi
发明人: Daniel Bradley , Clive Branch , Bethany Brown , Wai Chan , Steven Coulton , Martin Gilpin , Sharon Gough , Jacqueline MacRitchie , Howard Marshall , David Nash , Roderick Porter , Anthony Dean , Paul Doyle , Brian Evans , Luigi Stasi
IPC分类号: A61K31/535 , A61K31/497 , A61P25/18 , C07D401/02 , C07D401/14
CPC分类号: C07D213/73 , C07D213/75 , C07D213/85 , C07D215/38 , C07D239/42 , C07D241/44 , C07D295/192 , C07D487/04
摘要: The invention provides a compound of formula (I) or a salt or solvate thereof: wherein R1, n, X, Y and Z are as defined in the specification, and uses of such compounds. The compounds inhibit GlyT1 transporters and are useful in the treatment of certain neurological and neuropsychiatric disorders, including schizophrenia.
摘要翻译: 本发明提供式(I)化合物或其盐或溶剂合物:其中R 1,n,X,Y和Z如说明书中所定义,以及这些化合物的用途。 该化合物抑制GlyT1转运蛋白并且可用于治疗某些神经和神经精神障碍,包括精神分裂症。
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公开(公告)号:US08711734B2
公开(公告)日:2014-04-29
申请号:US13162701
申请日:2011-06-17
申请人: Rajan Iyengar , Gabriel Bourque , Brian Evans , Jason McCarthy , James Terhune
发明人: Rajan Iyengar , Gabriel Bourque , Brian Evans , Jason McCarthy , James Terhune
IPC分类号: H04L12/16
CPC分类号: H04L65/1069 , H04L65/1006 , H04L65/80 , H04L69/40
摘要: The present invention provides a system and method for fail-safe call survival by detecting failure of an active call serving component and switching the service over to a standby component. The system and method will prevent an existing call, whether established or to be established, from being dropped due to a single point of failure within a Voice over Internet Protocol system. The continuation of the call is based on the failed component as opposed to relying on communication endpoints to re-initiate or re-route the failed call. Call recovery is initiated independent from the call path of a call. The detection of a condition or need for call recovery and the determination to initiate call recovery procedures are made without involving endpoints or intermediate points of the call. The availability and sanity of all components are continuously monitored and are tailored specifically for the duties of each component.
摘要翻译: 本发明通过检测主动呼叫服务组件的故障并将业务切换到备用组件来提供用于故障安全呼叫生存的系统和方法。 该系统和方法将阻止由于因特网协议系统中的单一故障点而导致的已建立或未建立的呼叫被丢弃。 呼叫的继续是基于故障组件,而不是依靠通信端点重新启动或重新路由失败的呼叫。 呼叫恢复与呼叫的呼叫路径无关。 在不涉及呼叫的端点或中间点的情况下进行呼叫恢复的状况或需要的检测以及发起呼叫恢复过程的确定。 所有组件的可用性和完整性都将不断监控,并针对每个组件的职责量身定做。
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公开(公告)号:US20060235801A1
公开(公告)日:2006-10-19
申请号:US11108038
申请日:2005-04-14
申请人: Clifford Strom , Michael Siu , Brian Evans
发明人: Clifford Strom , Michael Siu , Brian Evans
IPC分类号: H04L9/00
CPC分类号: H04L63/0442 , G06F21/10 , G06F2221/2129 , H04L9/0825 , H04L9/083 , H04L63/0823 , H04L2209/603
摘要: A computing device has encrypted content and a corresponding license having a decryption key for decrypting the content. The license allows the computing device to render the content thereon. The computing device may issue a sub-license based on the license to a portable device. The sub-license allows the portable device to render the content thereon and has the decryption key. The portable device has a digital device certificate including information thereon. The computing device receives from the portable device the device certificate thereof, and determines based on rules in the license and the information on the portable device in the device certificate whether the computing device can issue the sub-license to the portable device. If so, the computing device constructs such sub-license to include the decryption key (KD) and transmits the constructed sub-license to the portable device.
摘要翻译: 计算设备具有加密内容和具有用于解密内容的解密密钥的相应许可证。 许可证允许计算设备在其上呈现内容。 计算设备可以基于许可证向便携式设备发布子许可证。 子许可证允许便携式设备在其上呈现内容并具有解密密钥。 便携式设备具有包括其上的信息的数字设备证书。 计算设备从便携式设备接收其设备证书,并且基于许可证中的规则和设备证书中的便携式设备上的信息来确定计算设备是否可以向便携式设备发布子许可证。 如果是这样,则计算设备构造这样的子许可证以包括解密密钥(KD),并将构造的子许可证发送到便携式设备。
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公开(公告)号:US20060235799A1
公开(公告)日:2006-10-19
申请号:US11107709
申请日:2005-04-14
申请人: Brian Evans , Clifford Strom , Geoffrey Dunbar , Richard Prologo
发明人: Brian Evans , Clifford Strom , Geoffrey Dunbar , Richard Prologo
IPC分类号: G06F17/60
CPC分类号: G06F21/10
摘要: A method is provided for a computing device to copy (burn) a playlist of tracks to a portable medium, where each track corresponds to a piece of digital content. At least one of the pieces of content is rights-management (RM) protected and accordingly is burned to the portable medium only in accordance with a corresponding digital license.
摘要翻译: 提供了一种用于计算设备将轨道播放列表复制(刻录)到便携式介质的方法,其中每个轨道对应于一段数字内容。 至少有一件内容是权限管理(RM)受保护的,因此仅根据相应的数字许可证将其烧录到便携式介质。
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