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    TRANSCUTANEOUSLY ADJUSTABLE FLUID-FILLED IMPLANTS
    1.
    发明申请
    TRANSCUTANEOUSLY ADJUSTABLE FLUID-FILLED IMPLANTS 审中-公开
    经过可调节的流体填充的植入物

    公开(公告)号：US20100249946A1

    公开(公告)日：2010-09-30

    申请号：US12412830

    申请日：2009-03-27

    申请人： Michael D. Lesh ,  Stewart Kume ,  Randy J. Kesten ,  Geoffrey Willis ,  Leo Centeno ,  Jeff Christian

    发明人： Michael D. Lesh ,  Stewart Kume ,  Randy J. Kesten ,  Geoffrey Willis ,  Leo Centeno ,  Jeff Christian

    IPC分类号： A61F2/02

    CPC分类号： A61F2/0059 ,  A61F2250/0003

    摘要： Disclosed are implantable tissue augmentation devices, methods, and associated tools. The devices include an inflatable body, having a self-sealing membrane operably attached to a wall of the implant. The self-sealing membrane provides access for filling the device, and includes a first layer comprising a fabric. The fabric has a first plurality of yarn strands positioned in a first direction, and a second plurality of yarn strands positioned in a second direction. The first and second plurality of yarn strands intersect to form a matrix pattern with cells defined by free spaces between yarn strands. The membrane also includes a first elastomeric material configured to fill the cells as well as form a coating over the first and second plurality of yarn strand, and a second layer comprising a second elastomeric material. The second elastomeric material has a lower durometer than the first elastomeric material. Kits and systems are also disclosed.

    摘要翻译： 公开了可植入组织增强装置，方法和相关联的工具。 所述装置包括可充气体，其具有可操作地附接到所述植入物的壁的自密封膜。 自密封膜提供用于填充装置的通路，并且包括包括织物的第一层。 织物具有沿第一方向定位的第一多根纱线和位于第二方向上的第二多根纱线。 第一和第二多根纱线相交以形成具有由纱线之间的自由空间限定的细胞的矩阵图案。 膜还包括构造成填充细胞并且在第一和第二多根纱线上形成涂层的第一弹性体材料，以及包含第二弹性体材料的第二层。 第二弹性体材料具有比第一弹性体材料低的硬度。 还披露了套件和系统。

    IMPLANTABLE PROSTHESIS WITH OPEN CELL FLOW REGULATION
    3.
    发明申请
    IMPLANTABLE PROSTHESIS WITH OPEN CELL FLOW REGULATION 审中-公开
    具有开放细胞流调节的可植入性

    公开(公告)号：US20090198331A1

    公开(公告)日：2009-08-06

    申请号：US12024846

    申请日：2008-02-01

    申请人： Randy J. Kesten ,  Michael D. Lesh

    发明人： Randy J. Kesten ,  Michael D. Lesh

    IPC分类号： A61F2/12

    CPC分类号： A61F2/12

    摘要： An implantable prosthesis is provided having a membrane which holds a flowable substance. The membrane is separated into a first chamber and a second chamber with the first and second chambers being fluidly coupled via an orifice. The orifice has a size which may be adjusted by the user after implanting the prosthesis into the patient.

    摘要翻译： 提供具有保持可流动物质的膜的可植入假体。 膜被分离成第一室和第二室，其中第一和第二室通过孔流体耦合。 孔口具有在将假体植入病人之后可由使用者调节的尺寸。

    BREAST IMPLANT WITH ADJUSTABLE COMPRESSION RESPONSE
    4.
    发明申请
    BREAST IMPLANT WITH ADJUSTABLE COMPRESSION RESPONSE 审中-公开
    乳房植入物可调节压力响应

    公开(公告)号：US20090198328A1

    公开(公告)日：2009-08-06

    申请号：US12024826

    申请日：2008-02-01

    申请人： Randy J. Kesten ,  Michael D. Lesh

    发明人： Randy J. Kesten ,  Michael D. Lesh

    IPC分类号： A61F2/12

    CPC分类号： A61F2/12

    摘要： An implantable prosthesis is provided having a membrane which holds a flowable substance. The membrane is separated into a first chamber and a second chamber with the first and second chambers being fluidly coupled via an orifice. The orifice has a size which may be adjusted by the user after implanting the prosthesis into the patient.

    摘要翻译： 提供具有保持可流动物质的膜的可植入假体。 膜被分离成第一室和第二室，其中第一和第二室通过孔流体耦合。 孔口具有在将假体植入病人之后可由使用者调节的尺寸。

    COMPRESSIBLE COSMETIC PROSTHESIS WITH IMPROVED SHAPE RETENTION
    6.
    发明申请
    COMPRESSIBLE COSMETIC PROSTHESIS WITH IMPROVED SHAPE RETENTION 审中-公开
    具有改进形状保持性的可压缩化妆品

    公开(公告)号：US20090198330A1

    公开(公告)日：2009-08-06

    申请号：US12024843

    申请日：2008-02-01

    申请人： Randy J. Kesten ,  Michael D. Lesh

    发明人： Randy J. Kesten ,  Michael D. Lesh

    IPC分类号： A61F2/12

    CPC分类号： A61F2/12

    摘要： An implantable prosthesis is provided having a membrane which holds a flowable substance. The membrane is separated into a first chamber and a second chamber with the first and second chambers being fluidly coupled via an orifice. The orifice has a size which may be adjusted by the user after implanting the prosthesis into the patient.

    摘要翻译： 提供具有保持可流动物质的膜的可植入假体。 膜被分离成第一室和第二室，其中第一和第二室通过孔流体耦合。 孔口具有在将假体植入病人之后可由使用者调节的尺寸。

    CIRCUMFERENTIAL ABLATION DEVICE ASSEMBLY
    9.
    发明申请
    CIRCUMFERENTIAL ABLATION DEVICE ASSEMBLY 有权
    循环消除装置组件

    公开(公告)号：US20090221996A1

    公开(公告)日：2009-09-03

    申请号：US12464473

    申请日：2009-05-12

    申请人： Michael D. Lesh

    发明人： Michael D. Lesh

    IPC分类号： A61B18/18 ,  A61B18/14 ,  A61B18/04 ,  A61N7/00

    CPC分类号： A61B18/1492 ,  A61B18/00 ,  A61B18/1815 ,  A61B2017/00243 ,  A61B2017/22038 ,  A61B2017/22054 ,  A61B2017/22067 ,  A61B2018/00011 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00369 ,  A61B2018/00375 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61B2018/00994 ,  A61B2218/002 ,  A61N7/02

    摘要： This invention is a circumferential ablation device assembly which is adapted to forming a circumferential conduction block in a pulmonary vein. The assembly includes a circumferential ablation element which is adapted to ablate a circumferential region of tissue along a pulmonary vein wall which circumscribes the pulmonary vein lumen, thereby transecting the electrical conductivity of the pulmonary vein against conduction along its longitudinal axis and into the left atrium. The circumferential ablation element includes an expandable member with a working length that is adjustable from a radially collapsed position to a radially expanded position. An equatorial band circumscribes the outer surface of the working length and is adapted to ablate tissue adjacent thereto when actuated by an ablation actuator. The equatorial band has a length relative to the longitudinal axis of the expandable member that is narrow relative to the working length, and is also substantially shorter than its circumference when the working length is in the radially expanded position. A pattern of insulators may be included over an ablation element which otherwise spans the working length in order to form the equatorial band described. The expandable member is also adapted to conform to the pulmonary vein in the region of its ostium, such as by providing a great deal of radial compliance or by providing a taper along the working length which has a distally reducing outer diameter. A linear ablation element is provided adjacent to the circumferential ablation element in a combination assembly which is adapted for use in a less-invasive “maze”-type procedure in the region of the pulmonary vein ostia in the left ventricle.

    摘要翻译： 本发明是适于在肺静脉中形成圆周传导阻滞的周缘消融装置组件。 该组件包括圆周消融元件，其适于沿着围绕肺静脉管腔的肺静脉壁消融组织的周缘区域，从而横切肺静脉的导电性，以抵抗沿着其纵向轴线并进入左心房的传导。 周向消融元件包括可膨胀构件，其具有可从径向收缩位置到径向扩张位置的可调节的工作长度。 赤道带包围工作长度的外表面，并且适于在由消融致动器致动时消融邻近的组织。 赤道带相对于可扩展构件的纵向轴线具有相对于工作长度窄的长度，并且当工作长度处于径向扩张位置时也比其圆周短得多。 绝缘体的图案可以包括在消融元件上，否则将跨越工作长度以形成所描述的赤道带。 可膨胀构件还适于在其口部的区域中符合肺静脉，例如通过提供大量径向顺应性或通过沿具有远端减小外径的工作长度提供锥形。 在组合组件中邻近周缘消融元件提供线性消融元件，该组合组件适用于在左心室的肺静脉口区域中的侵入性较小的“迷宫”型手术。