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1.
公开(公告)号:US06551302B1
公开(公告)日:2003-04-22
申请号:US09697672
申请日:2000-10-26
申请人: Michael J. Rosinko , Alexander Khairkhahan , Michael Horzewski , Stuart D. Harman , Richard L. Mueller , Douglas R. Murphy-Chutorian
发明人: Michael J. Rosinko , Alexander Khairkhahan , Michael Horzewski , Stuart D. Harman , Richard L. Mueller , Douglas R. Murphy-Chutorian
IPC分类号: A61M3100
CPC分类号: A61M25/0147 , A61B8/06 , A61B8/12 , A61M25/0084 , A61M25/0136 , A61M2025/0089
摘要: A steerable percutaneous catheter for guiding at least one functional device to selected surfaces of a body for treatment thereon, particularly adapted for laser-assisted Percutaneous Transmyocardial Revascularization (PTMR). The steerable catheter has a handle portion at its proximal end and a controllably deflectable end portion at its distal end. The distal end of the catheter and the distal end of the functional device maintain alignment automatically during deflection. The invention also includes a surface contact detection system to detect contact with an interior body surface, such as the heart wall.
摘要翻译: 一种可导向的经皮导管,用于将至少一个功能装置引导到身体的选定表面上用于在其上进行治疗,特别适用于激光辅助经皮心肌血运重建术(PTMR)。 可操纵的导管在其近端处具有手柄部分,在其远端具有可控制地偏转的端部。 导管的远端和功能装置的远端在偏转期间自动保持对准。 本发明还包括一个表面接触检测系统,用于检测与诸如心脏壁的内部身体表面的接触。
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公开(公告)号:US6123084A
公开(公告)日:2000-09-26
申请号:US216283
申请日:1998-12-18
CPC分类号: A61B18/08 , A61B2017/003 , A61B2018/00392 , A61B2018/00738 , A61B2018/1475
摘要: A method for improving blood flow in the heart provides a catheter system with an outer catheter defining at least one lumen and an inner catheter defining at least one lumen with proximal and distal portions. An introducer is coupled to the distal portion of the inner catheter. The introducer has a tissue piercing distal end. A resistive heater element is positioned in the introducer. The catheter system is introduced into a patient's vasculature. The inner catheter is then introduced through the a lumen of the outer catheter to a selected heart site. The tissue piercing distal end of the introducer is then advanced into an interior of the heart at the selected heart site. Energy is delivered to the selected heart site from the resistive heater element to create a blood conducting pathway and/or stimulate angiogenesis. In an alternative embodiment, a heart treatment apparatus is provided that includes a handpiece with a proximal and a distal end and an elongated member defining at least one lumen coupled to the handpiece distal end. The elongated member has a distal end and an introducer coupled to the distal end. The introducer has a tissue piercing distal end. A resistive heater element is positioned in the introducer. The tissue piercing distal end is introduced through a port in the chest wall into a chest cavity and through an epicardial surface of the heart wall to a selected site within the heart. Energy is delivered to the selected heart site from the resistive heater element to create a blood conducting pathway and/or stimulate angiogenesis.
摘要翻译: 用于改善心脏中的血液流动的方法提供了一种具有限定至少一个内腔的外导管和限定具有近端和远端部分的至少一个内腔的内导管的导管系统。 引导器联接到内导管的远端部分。 导引器具有组织穿刺远端。 电阻加热器元件位于导引器中。 将导管系统引入患者的脉管系统。 然后将内导管通过外导管的内腔引入选定的心脏部位。 然后导引器的组织穿刺远端在选定的心脏部位进入心脏的内部。 能量从电阻加热器元件输送到选定的心脏部位以产生血液传导途径和/或刺激血管发生。 在替代实施例中,提供了一种心脏治疗装置,其包括具有近端和远端的手持件以及限定连接到手持件远端的至少一个腔的细长构件。 细长构件具有远端和连接到远端的导引器。 导引器具有组织穿刺远端。 电阻加热器元件位于导引器中。 组织穿刺的远端通过胸壁中的口引入胸腔并通过心脏壁的心外膜表面到心脏内的选定位置。 能量从电阻加热器元件输送到选定的心脏部位以产生血液传导途径和/或刺激血管发生。
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公开(公告)号:US5855577A
公开(公告)日:1999-01-05
申请号:US797239
申请日:1997-02-07
CPC分类号: A61B18/24 , A61B2017/00247 , A61B2018/00392 , A61B2018/2211 , A61B90/39
摘要: A bow shaped, integrated wire catheter apparatus and method of use for access to, and laser or other treatment within, cavities and organs in the human body, the apparatus having a curvilinear shape but flexible enough to assume a generally elongated shape such that the apparatus can be extended through the vasculature in the generally elongated shape and can assume the curvilinear shape when extended into a body cavity or organ, the curvilinear shape serving to securely position the apparatus adjacent a selected surface within the body cavity or organ for laser or other treatment with a laser delivery device or other functional device thereon, the apparatus having a central axis, the apparatus comprising a main catheter shaft having a proximal end and an apex seeking and stabilizing distal end, the main catheter shaft having material of construction or other mechanism or means for causing a portion of the catheter shaft to have a bowed shape adjacent its distal end, the main catheter shaft having at least one hollow lumen extending axially and at least partially therethrough such that a bow shaped portion defines and distinguishes an outer arcuate sidewall for placement in contact with the selected area or areas for laser or other treatment thereon, and an inner arcuate sidewall, at least the outer arcuate sidewall having one or more guide holes disposed thereon for selectively providing laser or other treatment on the selected surface by controllably advancing a laser delivery device or other functional device selectively through the one or more guide holes to the selected surface. The catheter apparatus can be made at least partially of superelastic and/or shape memory materials of construction.
摘要翻译: 一种弓形,集成的导丝管装置和用于在人体内进入和激光或其他处理的空腔和器官的方法,该装置具有曲线形状,但足够柔软以呈现大致细长的形状,使得装置 可延伸通过脉管系统以大致细长的形状,并且当延伸到体腔或器官时可以呈现曲线形状,曲线形状用于将设备可靠地定位在体腔或器官内的选定表面以用于激光或其他治疗 其上具有激光输送装置或其它功能装置,所述装置具有中心轴线,所述装置包括主导管轴,所述主导管轴具有近端和寻求并稳定的远端的顶点,所述主导管轴具有构造材料或其它机构或 用于使导管轴的一部分具有邻近其远端(即主导管)的弓形的装置 轴具有轴向和至少部分地穿过其中延伸的至少一个中空腔,使得弓形部分限定和区分外弧形侧壁,用于与用于激光或其它处理的所选择的区域或区域接触,以及内弧形侧壁, 至少外弧形侧壁具有设置在其上的一个或多个引导孔,用于通过可选地将激光输送装置或其它功能装置选择性地推进到所选择的表面的一个或多个引导孔来选择性地在所选择的表面上提供激光或其他处理。 导管装置可以至少部分地由构造的超弹性和/或形状记忆材料制成。
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公开(公告)号:US20080064991A1
公开(公告)日:2008-03-13
申请号:US11804858
申请日:2007-05-21
申请人: Veijo Suorsa , Todd Thompson , Michael Horzewski
发明人: Veijo Suorsa , Todd Thompson , Michael Horzewski
IPC分类号: A61N7/00
CPC分类号: A61N7/00 , A61B8/4427 , A61B8/4444 , A61B90/50 , A61B2017/00725 , A61B2017/00734 , A61B2018/00023 , A61N2007/0073
摘要: Systems and methods deliver ultrasound energy to an ultrasound transducer. In one arrangement, the ultrasound energy is delivered at an output frequency that varies over time within a range of output frequencies. The systems and methods select from within the range an operating output frequency for the ultrasound transducer based upon preprogrammed selection rules. The systems and methods can deliver ultrasound energy to the ultrasound transducer at or near the operating output frequency selected, to perform a therapeutic or diagnostic function. In another arrangement, the systems and methods deliver ultrasound energy to the ultrasound transducer at or near a first output power condition to perform a first function, as well as at or near a second output power condition that differs from the first output power condition to perform a second function that differs from the first function. In this arrangement, the systems and methods deliver ultrasound energy to the ultrasound transducer at a power condition that transitions, according to a ramping function, from a condition at or near the first output power condition, for execution of the first function, toward a condition at or near the second output power condition, for execution of the second function. The ramping function may, e.g., be linear or non-linear.
摘要翻译: 系统和方法向超声波传感器提供超声能量。 在一种布置中,超声能量以在输出频率范围内随时间变化的输出频率传送。 系统和方法根据预编程的选择规则从范围内选择超声换能器的工作输出频率。 所述系统和方法可以在所选择的操作输出频率处或附近向超声换能器递送超声波能量,以执行治疗或诊断功能。 在另一种布置中,系统和方法在第一输出功率条件处或接近第一输出功率条件下向超声波换能器传送超声能量,以执行第一功能,以及在与第一输出功率条件不同的第二输出功率条件或附近,以执行 与第一功能不同的第二功能。 在这种布置中,系统和方法在超声换能器的功率条件下,向超声波换能器输送超声波能量,该功率状态根据斜坡函数从第一输出功率状态或接近第一输出功率状态的状态转移到第一功能的状态 在第二输出功率条件或其附近,用于执行第二功能。 斜坡函数可以例如是线性的或非线性的。
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公开(公告)号:US20070265601A1
公开(公告)日:2007-11-15
申请号:US11825873
申请日:2007-07-10
申请人: Michael Horzewski , Veijo Suorsa , Todd Thompson
发明人: Michael Horzewski , Veijo Suorsa , Todd Thompson
IPC分类号: A61B17/00
CPC分类号: A61N7/00 , A61B90/50 , A61B2017/00725 , A61B2017/00734 , A61B2018/00023 , A61N2007/0073
摘要: Systems and methods monitor and enable the use of a medical instrument that is configured to be operated in a prescribed manner. The systems and methods employ a use register sized and configured to be carried by the medical instrument, which comprises a memory field for recording a start date and time at an instance of first operation of the medical instrument. The systems and methods also employ a use monitoring controller, which is adapted and configured to be coupled to the use register. The use monitoring controller includes a start validation function that compares the start date and time to a present real date and time and provides a start validation output based upon the comparison. The use monitoring controller also includes an enablement function that enables operation of the medical instrument only if the start validation output meets prescribed criteria.
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公开(公告)号:US5873865A
公开(公告)日:1999-02-23
申请号:US797240
申请日:1997-02-07
申请人: Michael Horzewski , Jeffrey Giba
发明人: Michael Horzewski , Jeffrey Giba
CPC分类号: A61M25/0041 , A61M25/0662 , A61M2210/125 , A61M25/007
摘要: A spiral catheter apparatus for access to, and laser or other treatment within, cavities and organs in the human body, the apparatus comprising a flexible, main catheter shaft defining a central axis of the apparatus, the catheter shaft having a proximal end, a distal end and a first hollow lumen region extending therethrough, the catheter shaft further having a spiral portion adjacent the distal end with a selected curvilinear shape, the curvilinear shape defining an inner arcuate sidewall and an outer arcuate sidewall, the catheter shaft flexible enough to assume a temporarily elongated shape such that the apparatus can be extended through at least a portion of the body in the temporarily elongated shape and will assume the selected curvilinear shape when extended into a body cavity or organ, the selected curvilinear shape serving to securely position the apparatus adjacent a selected surface within the body cavity or organ, at least the spiral portion of the catheter shaft having a plurality of guide holes thereon, the plurality of guide holes disposed at least on the outer arcuate sidewall in communication with the first lumen such that a distal end of a laser delivery means or other functional device can be controllably advanced through the plurality of guide holes for laser or other treatment on the selected surface.
摘要翻译: 一种螺旋导管装置,用于进入人体内的空腔和器官内的激光或其他处理,所述装置包括限定所述装置的中心轴线的柔性主导管轴,所述导管轴具有近端,远端 端部和延伸穿过其中的第一中空腔区域,所述导管轴还具有邻近所述远端的螺旋部分,所述螺旋部分具有选定的曲线形状,所述曲线形状限定内弧形侧壁和外弧形侧壁,所述导管轴足够柔性以呈现 临时细长的形状,使得装置可以延伸穿过身体的暂时细长形状的至少一部分,并且当延伸到体腔或器官时将呈现出所选择的曲线形状,所选择的曲线形状用于将装置安全地定位在邻近 所述体腔或器官中的选定表面,至少所述导管轴的螺旋部分具有a 多个引导孔,多个引导孔至少设置在与第一管腔连通的外弧形侧壁上,使得激光输送装置或其他功能装置的远端可以可控地前进通过多个引导孔,用于 激光或其他处理。
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公开(公告)号:US06126654A
公开(公告)日:2000-10-03
申请号:US256126
申请日:1999-02-24
CPC分类号: A61M25/0138 , A61B18/24 , A61M25/0136 , A61M25/0141 , A61M25/0144 , A61M25/0147 , A61M25/0152 , A61M25/0158 , A61B2017/00247 , A61B2017/00336 , A61B2018/00392 , A61B2018/00738
摘要: An elongated steerable catheter for placement within a heart chamber, organ aperture or other body opening and having at least one center tube with hollow passageway for guiding a laser delivery means or other functional device to selected surfaces of a heart chamber, organ aperture or other body cavity for laser or other treatment thereon, particularly adapted for laser-assisted percutaneous transmyocardial revascularization (TMR), is disclosed herein. The steerable catheter has a handle portion at its proximal end and a controllably deflectable end portion at its distal end. The elongated center tube has a distal end, in the region where a curvature is to be formed, and a shim anchor sleeve is slidably disposed over the center tube. The shim anchor sleeve is attached to the inside wall of the outer jacket and coupled to the distal end of the center tube with a bendable shim member which extends between the distal tip of the steerable catheter and the sleeve over the center tube. Opposite the shim is a guide for a pull cable, the pull cable attached to the distal end of the steerable catheter and extending through the guide to the handle. Thus, the shim is maintained radially opposite the pull cable with the center tube in between. An outer jacket has, in a preferred embodiment, distinct sections of different stiffness or durometer. A distal, more flexible portion is coupled to a proximal, stiffer portion. The shim anchor sleeve is positioned at or near the junction of two portions of the outer jacket. Thus, the center tube moves freely through the shim anchor sleeve. Adjacent the handle, the outer jacket terminates at the catheter base. The pull cable extends past the catheter base, through a deflection housing tube, and terminates in a cable stop. Rotation of a deflection knob threadably mounted onto the deflection housing tube will cause the pull cable to be pulled backward, or the outer jacket to be pushed forward, relative to each other, thereby inducing deflection of the distal end of the steerable catheter.
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公开(公告)号:US20060211955A1
公开(公告)日:2006-09-21
申请号:US11438717
申请日:2006-05-22
申请人: Michael Horzewski , Alan Kaganov , Veijo Suorsa , Todd Thompson
发明人: Michael Horzewski , Alan Kaganov , Veijo Suorsa , Todd Thompson
CPC分类号: A61H23/0236 , A61B90/50 , A61B2017/00725 , A61B2017/00734 , A61B2018/00023 , A61N7/00 , A61N2007/0073
摘要: Systems and methods stimulate circulatory activity in a targeted body region of an individual by applying ultrasound energy. Before, during or after the application of ultrasound energy, the systems and methods administer an agent to individual that results, e.g., in an angiogenic effect, or in a reduction of blood perfusion, or a chemotherapy effect. The application of ultrasound energy selectively increases blood perfusion or uptake of the agent in the targeted body region.
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公开(公告)号:US06530913B1
公开(公告)日:2003-03-11
申请号:US09621246
申请日:2000-07-21
IPC分类号: A61M2501
CPC分类号: A61M25/0138 , A61B18/24 , A61B2017/00247 , A61B2017/00336 , A61B2018/00392 , A61B2018/00738 , A61M25/0136 , A61M25/0141 , A61M25/0144 , A61M25/0147 , A61M25/0152 , A61M25/0158
摘要: An elongated steerable catheter for placement within a heart chamber, organ aperture or other body opening and having at least one center tube with hollow passageway for guiding a laser delivery means or other functional device to selected surfaces of a heart chamber, organ aperture or other body cavity for laser or other treatment thereon, particularly adapted for laser-assisted percutaneous transmyocardial revascularization (TMR), is disclosed herein. The steerable catheter has a handle portion at its proximal end and a controllably deflectable end portion at its distal end. The elongated center tube has a distal end, in the region where a curvature is to be formed, and a shim anchor sleeve is slidably disposed over the center tube. The shim anchor sleeve is attached to the inside wall of the outer jacket and coupled to the distal end of the center tube with a bendable shim member which extends between the distal tip of the steerable catheter and the sleeve over the center tube. Opposite the shim is a guide for a pull cable, the pull cable attached to the distal end of the steerable catheter and extending through the guide to the handle. Thus, the shim is maintained radially opposite the pull cable with the center tube in between. An outer jacket has, in a preferred embodiment, distinct sections of different stiffness or durometer. A distal, more flexible portion is coupled to a proximal, stiffer portion. The shim anchor sleeve is positioned at or near the junction of two portions of the outer jacket. Thus, the center tube moves freely through the shim anchor sleeve. Adjacent the handle, the outer jacket terminates at the catheter base. The pull cable extends past the catheter base, through a deflection housing tube, and terminates in a cable stop. Rotation of a deflection knob threadably mounted onto the deflection housing tube will cause the pull cable to be pulled backward, or the outer jacket to be pushed forward, relative to each other, thereby inducing deflection of the distal end of the steerable catheter.
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公开(公告)号:US5730741A
公开(公告)日:1998-03-24
申请号:US796636
申请日:1997-02-07
申请人: Michael Horzewski , Jeffrey Giba
发明人: Michael Horzewski , Jeffrey Giba
CPC分类号: A61M25/09 , A61B18/24 , A61B2017/00247 , A61B2017/00867 , A61B2017/22077 , A61B2018/00392 , A61M25/0041
摘要: A spiral catheter apparatus and method of use for access to, and laser or other treatment within, cavities and organs in the human body, the apparatus having a spiral member with a selected curvilinear shape, but flexible enough to assume a temporarily elongated shape such that the spiral member can be extended through the vasculature in the temporarily elongated shape and will assume the selected curvilinear shape when extended into a body cavity or organ, the spiral member formed of a superelastic or other material, the selected curvilinear shape serving to securely position the spiral member adjacent a selected surface within the body cavity or organ for laser or other treatment with a laser delivery device or other functional device on a selected surface, the apparatus further having a main catheter shaft with at least two hollow lumens extending therethrough, the first lumen for slidably guiding the main catheter shaft over the spiral member into a first position adjacent the selected surface, and the second lumen having a guide hole adjacent the distal end of the main catheter shaft for advancing a laser delivery device or other functional device through the guide hole for laser or other treatment on the selected surface within the body cavity or organ.
摘要翻译: 一种螺旋导管装置和用于在人体内进入和激光或其它处理的空腔和器官的方法,所述装置具有具有选定曲线形状的螺旋构件,但是具有足够的柔性以呈现临时细长的形状,使得 螺旋构件可以以暂时细长的形状延伸穿过脉管系统,并且当延伸到体腔或器官中时呈现选定的曲线形状,螺旋构件由超弹性或其它材料形成,所选择的曲线形状用于将 螺旋构件邻近所述体腔或器官中的选定表面,用于在所选择的表面上用激光输送装置或其他功能装置进行激光或其它处理,所述装置还具有主导管轴,所述主导管轴具有延伸穿过其中的至少两个空腔,所述第一 内腔,用于将主导管轴可滑动地引导到螺旋构件上方到靠近塞子的第一位置 并且第二内腔具有与主导管轴的远端相邻的引导孔,用于使激光输送装置或其他功能装置通过用于激光或其它处理的引导孔在体腔或器官内的选定表面上前进。
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