公开(公告)号：US20180250058A1

公开(公告)日：2018-09-06

申请号：US15912187

申请日：2018-03-05

Applicant: Regents of the University of Minnesota ,  MicroVention, Inc.

Inventor： Bharathi Jagadeesan ,  Sean Lester Moen ,  George R. Greene, JR.

IPC: A61B18/06 ,  A61L24/00 ,  A61L24/02 ,  A61L24/06

CPC classification number: A61B18/06 ,  A61B17/12186 ,  A61B18/04 ,  A61B18/18 ,  A61B2018/00577 ,  A61B2090/3966 ,  A61L24/00 ,  A61L24/001 ,  A61L24/02 ,  A61L24/06 ,  A61L2400/06 ,  A61L2430/36 ,  A61M37/0092 ,  A61N5/00 ,  A61N7/02 ,  C08L33/10 ,  C08L23/08

Abstract: An embolic agent and a piezoelectric substance are mixed together. The mixture can be delivered to a tumor or other object by a non-invasive method. The embolic agent prevents movement of the piezoelectric substance from the target location. Subsequent impulses applied to the target location cause ablation of the surrounding area due to the piezoelectric effect of the particles, promoting highly accurate and precise ablation without the need for more invasive procedures.

公开(公告)号：US20180070955A1

公开(公告)日：2018-03-15

申请号：US15786393

申请日：2017-10-17

Applicant: MicroVention, Inc.

Inventor： George R. Greene, JR. ,  Ivan Sepetka ,  Cathy Lei ,  Alejandro Berenstein ,  Monika Killer-Oberpfalzer ,  Heath Bowman

IPC: A61B17/12

CPC classification number: A61B17/12186 ,  A61B17/12031 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/12136 ,  A61B17/12168 ,  A61B17/12172 ,  A61B2017/00526 ,  A61B2017/00867 ,  A61B2017/1205 ,  A61B2017/12054 ,  A61B2017/12059 ,  A61B2017/12063 ,  A61B2017/12068 ,  A61B2017/12095 ,  A61B2090/3966 ,  A61F2/01 ,  A61F2250/0039

Abstract: Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.

公开(公告)号：US20170367713A1

公开(公告)日：2017-12-28

申请号：US15599284

申请日：2017-05-18

Applicant: MicroVention, Inc.

Inventor： George R. Greene, JR. ,  Ivan Sepetka ,  Cathy Lei ,  Alejandro Berenstein ,  Monika Killer-Oberpfalzer

IPC: A61B17/12

CPC classification number: A61B17/12172 ,  A61B17/12031 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/12136 ,  A61B17/12177 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/00526 ,  A61B2017/00867 ,  A61B2017/1205 ,  A61B2017/12063 ,  A61B2017/12095 ,  A61B2090/3966 ,  A61F2002/823

Abstract: Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.

公开(公告)号：US20250082338A1

公开(公告)日：2025-03-13

申请号：US18895334

申请日：2024-09-24

Applicant: MicroVention, Inc.

Inventor： Hideo Morita ,  Greg Bak-Boychuk ,  Arnold Tuason ,  Matthew J. Fitz ,  George R. Greene, JR.

IPC: A61B17/12 ,  A61B17/00 ,  A61L31/14 ,  A61M25/00

Abstract: An expansile member that may be used on a delivery device or may be used for occlusive purposes within the vasculature.

公开(公告)号：US20150174381A1

公开(公告)日：2015-06-25

申请号：US14548209

申请日：2014-11-19

Applicant: MicroVention, Inc.

Inventor： Hideo Morita ,  Greg Bak-Boychuk ,  Arnold Tuason ,  Matthew J. Fitz ,  George R. Greene, JR.

IPC: A61M25/10

CPC classification number: A61B17/1219 ,  A61B17/00491 ,  A61B17/12113 ,  A61B17/12172 ,  A61B17/12186 ,  A61B2017/00243 ,  A61B2017/00575 ,  A61B2017/00606 ,  A61B2017/00623 ,  A61B2017/00898 ,  A61B2017/12054 ,  A61L31/14 ,  A61L31/145 ,  A61M25/0082 ,  A61M2025/0042 ,  A61M2025/0096

Abstract: An expansile member is described. The expansile member may be used on a delivery device or may be used for occlusive purposes within the vasculature.

Abstract translation: 描述了一个扩展成员。 膨胀构件可以在输送装置上使用或者可以用于脉管系统内的闭塞目的。

公开(公告)号：US20140257245A1

公开(公告)日：2014-09-11

申请号：US14286893

申请日：2014-05-23

Applicant: MicroVention, Inc.

Inventor： Robert F. Rosenbluth ,  George R. Greene, JR. ,  Brian J. Cox ,  Thomas S. Sternweiler ,  Sean L. Chow ,  Richard R. Monetti ,  Teresa L. Halverson ,  Maricela D. Walker ,  Robert Pecor

IPC: A61B17/22 ,  A61B17/221

CPC classification number: A61B17/22032 ,  A61B17/135 ,  A61B17/221 ,  A61B2017/22034 ,  A61B2017/22044 ,  A61B2017/22077 ,  A61B2017/22084 ,  A61B2017/22094 ,  A61B2017/2212 ,  A61B2017/320716 ,  A61F2/013 ,  A61F2002/016 ,  A61F2002/018 ,  A61F2230/008 ,  A61F2230/0091 ,  A61M2025/0042 ,  A61M2025/0183

Abstract: Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing clots or other obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable with or over a guidewire which has been pre-inserted through or around the clot. Also, in some embodiments, the embolectomy catheters include clot removal devices which are deployable from the catheter after the catheter has been advanced at least partially through the clot. The clot removal device may include a deployable wire nest that is designed to prevent a blood clot from passing therethrough. The delivery catheter may include telescoping inner and outer tubes, with the clot removal device being radially constrained by the outer tube. Retraction of the outer tube removes the constraint on the clot removal device and permits it to expand to its deployed configuration. An infusion guidewire is particularly useful in conjunction with the embolectomy catheter, and permits infusion of medicaments or visualization fluids distal to the clot.

Abstract translation: 用于从血管中去除凝块或其他阻塞物（例如，血栓，血栓栓塞，动脉粥样硬化斑块的栓塞碎片，异物等）的系统和方法，快速交换微导管。 本发明特别可用于在脑卒中或脑缺血期间经皮去除血栓栓塞或其他来自脑小血管的阻塞物质。 在一些实施例中，本发明的止血栓塞导管可以在已经插入穿过凝块或围绕凝块的导丝上或之上前进。 此外，在一些实施例中，止血管切除导管包括在导管至少部分地穿过血块前进之后可从导管展开的凝块移除装置。 凝块移除装置可以包括被设计成防止血块从其中通过的可展开的线巢。 输送导管可以包括伸缩的内管和外管，其中血块去除装置由外管径向约束。 外管的收缩消除了对凝块去除装置的约束，并允许其扩展到其部署构型。 输注导丝特别适用于结肠切除术导管，并且可以输送远离凝块的药物或可视化液体。

公开(公告)号：US20230310056A1

公开(公告)日：2023-10-05

申请号：US18332553

申请日：2023-06-09

Applicant: Regents of the University of Minnesota ,  MicroVention, Inc.

Inventor： Bharathi Jagadeesan ,  Sean Lester Moen ,  George R. Greene, JR.

IPC: A61B18/04 ,  A61N5/00 ,  A61B18/18 ,  A61L24/00 ,  A61L24/02 ,  A61L24/06 ,  A61B18/06 ,  A61B17/12 ,  A61N7/02

CPC classification number: A61B18/06 ,  A61B17/12186 ,  A61B18/04 ,  A61B18/18 ,  A61L24/00 ,  A61L24/001 ,  A61L24/02 ,  A61L24/06 ,  A61N5/00 ,  A61N7/02 ,  A61B2018/00577 ,  A61L2430/36

Abstract: An embolic agent and a piezoelectric substance are mixed together. The mixture can be delivered to a tumor or other object by a non-invasive method. The embolic agent prevents movement of the piezoelectric substance from the target location. Subsequent impulses applied to the target location cause ablation of the surrounding area due to the piezoelectric effect of the particles, promoting highly accurate and precise ablation without the need for more invasive procedures.

公开(公告)号：US20220401104A1

公开(公告)日：2022-12-22

申请号：US17822090

申请日：2022-08-24

Applicant: MicroVention, Inc.

Inventor： Hideo Morita ,  Greg Bak-Boychuk ,  Arnold Tuason ,  Matthew J. Fitz ,  George R. Greene, JR.

IPC: A61B17/12 ,  A61M25/00 ,  A61L31/14

Abstract: An expansile member that may be used on a delivery device or may be used for occlusive purposes within the vasculature.

公开(公告)号：US20210137530A1

公开(公告)日：2021-05-13

申请号：US17125840

申请日：2020-12-17

Applicant: MicroVention, Inc.

Inventor： George R. Greene, JR. ,  Ivan Sepetka ,  Cathy Lei ,  Alejandro Berenstein ,  Monika Killer-Oberpfalzer

IPC: A61B17/12

Abstract: Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.

公开(公告)号：US20190192165A1

公开(公告)日：2019-06-27

申请号：US16289485

申请日：2019-02-28

Applicant: MicroVention, Inc. ,  University of Virginia Patent Foundation ,  United States of America As Represented By The Secretary Of The Navy

Inventor： George R. Greene, JR. ,  Ivan Sepetka ,  Cathy Lei ,  Rupal Nguyen ,  Matthew J. Bradley ,  Stephen T. Ahlers ,  Carl W. Goforth ,  James R. Stone

IPC: A61B17/12

CPC classification number: A61B17/12109 ,  A61B17/1204 ,  A61B17/12136 ,  A61B17/1214 ,  A61B2017/1205 ,  A61B2090/0807

Abstract: A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries.