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公开(公告)号：US06228388B1
公开(公告)日：2001-05-08
申请号：US08852600
申请日：1997-05-07
IPC分类号： A61K3100
CPC分类号： A61K33/06 , A61K33/10 , Y10S514/904 , Y10S514/905 , A61K31/714 , A61K31/59 , A61K31/51 , A61K31/505 , A61K31/44 , A61K2300/00
摘要： Multi-vitamin and mineral supplements for administration to a pregnant woman during her first, second, and third trimesters of pregnancy comprising specific regimens of a pharmaceutically acceptable calcium compound, vitamin D, folic acid, vitamin B12, vitamin B6, and vitamin B1. The prenatal supplements are specifically tailored to maximize fetal development and maternal health during each trimester of pregnancy.
摘要翻译： 在孕妇的第一，第二和第三三个月期间对怀孕妇女施用的多种维生素和矿物质补充物包括药学上可接受的钙化合物，维生素D，叶酸，维生素B12，维生素B6和维生素B1的具体方案。 产前补品专门用于在妊娠三个月期间最大限度地发挥胎儿发育和产妇健康。
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公开(公告)号：US5494678A
公开(公告)日：1996-02-27
申请号：US410733
申请日：1995-03-27
CPC分类号： A61K33/06 , A61K33/10 , Y10S514/904 , Y10S514/905
摘要： Multi-vitamin and mineral supplements for administration to a pregnant woman during her first, second, and third trimesters of pregnancy comprising specific regimens of a pharmaceutically acceptable calcium compound, vitamin D, folic acid, vitamin B.sub.12, vitamin B.sub.6, and vitamin B.sub.1. The prenatal supplements are specifically tailored to maximize fetal development and maternal health during each trimester of pregnancy.
摘要翻译： 在孕妇的第一，第二和第三三个月期间对怀孕妇女施用的多种维生素和矿物质补充物包括药学上可接受的钙化合物，维生素D，叶酸，维生素B12，维生素B6和维生素B1的具体方案。 产前补品专门用于在妊娠三个月期间最大限度地发挥胎儿发育和产妇健康。
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公开(公告)号：US06261600B1
公开(公告)日：2001-07-17
申请号：US09303000
申请日：1999-04-30
IPC分类号： A61K946
CPC分类号： A61K9/0056 , A23K20/174 , A23L33/15 , A23V2002/00 , A61K9/2009 , A23V2250/7056 , A23V2250/1564 , A23V2250/1578 , A23V2250/628
摘要： The present invention is directed to novel chewable or dissolvable nutritional supplements for improving the absorption of folic acid in humans and other animals and methods of using said supplements. The nutritional supplements contain folic acid and non-toxic acid neutralizing alkaline compounds in chewable or dissolvable forms.
摘要翻译： 本发明涉及用于改善人类和其他动物中叶酸吸收的新型可咀嚼或可溶解的营养补充剂以及使用所述补充剂的方法。 营养补充剂含有叶酸和无毒酸中和碱性化合物，其咀嚼或溶解形式。
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公开(公告)号：US07687485B2
公开(公告)日：2010-03-30
申请号：US10106381
申请日：2002-03-27
IPC分类号： A61K31/56 , A61K31/44 , A61K31/335 , A61K31/34
CPC分类号： A61K45/06 , A23L33/12 , A23L33/15 , A23L33/16 , A23V2002/00 , Y10S514/899 , A23V2250/211 , A23V2250/70 , A23V2250/156 , A23V2250/1868 , A23V2250/1874 , A23V2250/1872 , A23V2250/71 , A23V2250/712 , A23V2250/708 , A23V2250/704 , A23V2250/1578 , A23V2250/1588 , A23V2250/1642 , A23V2250/1626 , A23V2250/18 , A23V2250/30 , A23V2250/1592 , A23V2250/161 , A23V2200/224 , A23V2250/5432
摘要： The present disclosure relates to novel compositions which provide improved nutritional support for premenopausal and menopausal women and/or relief from symptoms associated with menopause, as well as prophylactic effects, and methods for using same.
摘要翻译： 本公开涉及提供改善的对绝经前和绝经期妇女的营养支持和/或缓解与绝经相关的症状以及预防效果的新型组合物及其使用方法。
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公开(公告)号：US06696083B1
公开(公告)日：2004-02-24
申请号：US09016786
申请日：1998-01-30
IPC分类号： A61K952
CPC分类号： A61K31/714 , A61K31/01 , A61K31/015 , A61K31/355 , A61K31/375 , A61K31/4415 , A61K31/51 , A61K38/063 , A61K45/06
摘要： The efficacy of vitamins and other nutritional agents in treating and preventing various disease states is improved by administering therapeutically effective levels of these agents on a substantially continuous, 24-hour basis. The concentration of lipid peroxides formed by the autoxidation of lipids, and the concentration of oxygen free radicals, are reduced by continuously administering antioxidant agents. The regeneration of nerve tissue is improved by continuously administering at least one pharmaceutically-acceptable B complex vitamin.
摘要翻译： 通过在基本上连续的24小时的基础上施用治疗有效量的这些药剂来改善维生素和其它营养剂治疗和预防各种疾病状态的功效。 通过持续施用抗氧化剂，减少通过脂质的自动氧化形成的脂质过氧化物的浓度和氧自由基的浓度。 通过连续施用至少一种药学上可接受的B复合维生素来改善神经组织的再生。
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公开(公告)号：US5554379A
公开(公告)日：1996-09-10
申请号：US262254
申请日：1994-06-20
CPC分类号： A61K9/006 , A61K9/0056 , A61K9/0058
摘要： A bioadherent, orally ingestible system, which comprises: a water-in-oil system having at least two phases, one phase comprises from about 75% to about 99% by volume of an internal hydrophylic phase and the other phase comprises from about 25% to about l% by volume of an external hydrophobic phase, wherein the external hydrophobic phase comprises two components, one component being about 3% to about 97% by volume of the hydrophobic phase of a hydrophobic oil and the other being about 97% to about 3% of an emulsifier having a HLB value less than about 10.
摘要翻译： 一种生物相容的口服摄取系统，其包括：具有至少两相的油包水体系，一相包含约75％至约99％体积的内部亲水相，另一相包含约25％ 至约1体积％的外部疏水相，其中外部疏水相包含两种组分，一种组分为疏水相的疏水性油的约3％至约97体积％，另一种为约97％至约 3％的HLB值小于约10的乳化剂。
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公开(公告)号：US06479545B1
公开(公告)日：2002-11-12
申请号：US09409059
申请日：1999-09-30
IPC分类号： A61K31185
CPC分类号： A61K45/06 , A23L33/12 , A23L33/15 , A23L33/16 , A23V2002/00 , Y10S514/899 , A23V2250/211 , A23V2250/70 , A23V2250/156 , A23V2250/1868 , A23V2250/1874 , A23V2250/1872 , A23V2250/71 , A23V2250/712 , A23V2250/708 , A23V2250/704 , A23V2250/1578 , A23V2250/1588 , A23V2250/1642 , A23V2250/1626 , A23V2250/18 , A23V2250/30 , A23V2250/1592 , A23V2250/161 , A23V2200/224 , A23V2250/5432
摘要： The present disclosure relates to novel compositions which provide improved nutritional support for premenopausal and menopausal women and/or relief from symptoms associated with menopause, as well as prophylactic effects, and methods for using same.
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公开(公告)号：US5554380A
公开(公告)日：1996-09-10
申请号：US441297
申请日：1995-05-15
申请人： Robert C. Cuca , Keith S. Lienhop , Thomas C. Riley, Jr. , R. Saul Levinson , Mitchell I. Kirschner
发明人： Robert C. Cuca , Keith S. Lienhop , Thomas C. Riley, Jr. , R. Saul Levinson , Mitchell I. Kirschner
CPC分类号： A61K9/0058 , A61K9/006
摘要： A solid or semi-solid bioadherent, orally ingestible drug delivery system containing a water-in-oil system having at least two phases, one phase comprises from about 25% to about 75% by volume of an internal hydrophilic phase and the other phase comprises from about 25% to about 75% by volume of an external hydrophobic phase and wherein the external hydrophobic phase is comprised of three components, a) an emulsifier, b) a glyceride ester and c) a wax material.
摘要翻译： 包含至少两相的油包水系统的固体或半固体生物粘附的口服摄取药物递送系统，一相包含约25体积％至约75体积％的内部亲水相，而另一相包含 约25％至约75％体积的外部疏水相，并且其中所述外部疏水相由三种组分组成，a）乳化剂，b）甘油酯和c）蜡材料。
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公开(公告)号：US06899890B2
公开(公告)日：2005-05-31
申请号：US10101014
申请日：2002-03-20
IPC分类号： A61K9/10 , A61F6/06 , A61K9/00 , A61K31/4164 , A61K31/7028 , A61K45/00 , A61K47/12 , A61P5/24 , A61P15/00 , A61P15/02 , A61P15/18 , A61P31/04 , A61P33/02 , A61F13/02 , A61F6/14 , A61K9/107 , A61N25/34
CPC分类号： A61K47/12 , A61K9/0034 , Y02A50/473 , Y02A50/481
摘要： The present invention relates to a novel essentially pH neutral vaginal drug delivery system suitable for modified delivery of a therapeutically active material in the vaginal cavity. The vaginal drug delivery system comprises an essentially pH neutral emulsion having globules having two phases, an internal water soluble phase and an external water-insoluble phase or film, wherein the water-soluble interior phase contains a therapeutically active drug or drugs. One novel aspect of the vaginal drug delivery system is that the internal water soluble phase comprises an acidic buffered phase.
摘要翻译： 本发明涉及一种新颖的基本上pH为中性的阴道药物递送系统，其适于在阴道腔中修饰递送治疗活性物质。 阴道药物递送系统包括基本上具有两相球形的pH中性乳液，内部水溶性相和外部水不溶性相或膜，其中所述水溶性内相含有治疗活性药物或药物。 阴道药物递送系统的一个新颖方面是内部水溶性相包含酸性缓冲相。
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公开(公告)号：US06352713B1
公开(公告)日：2002-03-05
申请号：US09451849
申请日：1999-12-01
IPC分类号： A61K928
CPC分类号： A61K33/30 , A23L33/15 , A23L33/16 , A23V2002/00 , A61K9/0056 , A23V2250/708 , A23V2250/7052 , A23V2250/7106 , A23V2250/712 , A23V2250/1592 , A23V2250/1588 , A23V2250/161 , A23V2250/71 , A23V2250/1642 , A61K2300/00 , A23V2250/211 , A23V2250/704 , A23V2250/702 , A23V2250/705 , A23V2250/156 , A23V2250/70 , A23V2250/1578 , A23V2250/1608 , A23V2250/1586 , A23V2250/16
摘要： The present inventive subject matter is directed to novel chewable prenatal nutritional supplements which contain vitamin C, as well as novel methods for providing optimal vitamin C supplementation to pregnant women. The present invention is also directed to novel compositions and methods for providing nutritional supplementation to individuals planning to conceive a child.
摘要翻译： 本发明主题涉及含有维生素C的新型咀嚼产前营养补充剂，以及用于向孕妇提供最佳维生素C的新方法。 本发明还涉及用于向计划设想孩子的个人提供营养补充的新型组合物和方法。
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