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公开(公告)号：US08784829B2
公开(公告)日：2014-07-22
申请号：US13125019
申请日：2009-10-21
IPC分类号： A61K39/02 , A61K39/00 , A61K39/38 , A61K38/00 , C07K2/00 , C07K4/00 , C07K5/00 , C07K7/00 , C07K14/00 , C07K16/00 , C07K17/00
CPC分类号： C07K14/205 , A61K38/00 , A61K39/105 , A61K2039/53 , G01N33/56911
摘要： The present invention relates to polynucleotide sequences encoding novel Lawsonia intracellularis polypeptides. It also relates to DNA fragments, recombinant plasmid DNA and live recombinant microorganisms comprising these sequences. Moreover, the invention relates to polypeptides encoded by these nucleotide sequences. The invention also relates to immunogenic compositions for prevention of Lawsonia intracellularis infections and methods for the preparation of these immunogenic compositions. The invention also relates to diagnostic tests for the detection of Lawsonia intracellularis DNA, the detection of Lawsonia intracellularis antigens and detection of antibodies against Lawsonia intracellularis.
摘要翻译： 本发明涉及编码新的胞内劳森氏菌多肽的多核苷酸序列。 它还涉及DNA片段，重组质粒DNA和包含这些序列的活重组微生物。 此外，本发明涉及由这些核苷酸序列编码的多肽。 本发明还涉及用于预防细胞内劳森氏菌感染的免疫原性组合物和用于制备这些免疫原性组合物的方法。 本发明还涉及检测细胞内劳氏梭菌DNA，检测细胞内劳森氏菌抗原以及检测针对胞内劳森氏菌的抗体的诊断试验。
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公开(公告)号：US20110200631A1
公开(公告)日：2011-08-18
申请号：US13125019
申请日：2009-10-21
IPC分类号： A61K39/02 , C07K14/195 , G01N33/566 , C07H21/00 , C07H21/04 , A61P31/04 , A61P37/04
CPC分类号： C07K14/205 , A61K38/00 , A61K39/105 , A61K2039/53 , G01N33/56911
摘要： The present invention relates to polynucleotide sequences encoding novel Lawsonia intracellularis polypeptides. It also relates to DNA fragments, recombinant plasmid DNA and live recombinant microorganisms comprising these sequences. Moreover, the invention relates to polypeptides encoded by these nucleotide sequences. The invention also relates to immunogenic compositions for prevention of Lawsonia intracellularis infections and methods for the preparation of these immunogenic compositions. The invention also relates to diagnostic tests for the detection of Lawsonia intracellularis DNA, the detection of Lawsonia intracellularis antigens and detection of antibodies against Lawsonia intracellularis.
摘要翻译： 本发明涉及编码新的胞内劳森氏菌多肽的多核苷酸序列。 它还涉及DNA片段，重组质粒DNA和包含这些序列的活重组微生物。 此外，本发明涉及由这些核苷酸序列编码的多肽。 本发明还涉及用于预防细胞内劳森氏菌感染的免疫原性组合物和用于制备这些免疫原性组合物的方法。 本发明还涉及检测细胞内劳氏梭菌DNA，检测细胞内劳森氏菌抗原以及检测针对胞内劳森氏菌的抗体的诊断试验。
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公开(公告)号：US20100166803A1
公开(公告)日：2010-07-01
申请号：US12616341
申请日：2009-11-11
申请人： Steve Hewart Fitz-Coy , Gamini Saman Kumara Withanage , Alexandria Louise McGowan , Stephanie M. Cook
发明人： Steve Hewart Fitz-Coy , Gamini Saman Kumara Withanage , Alexandria Louise McGowan , Stephanie M. Cook
IPC分类号： A61K39/012 , C12Q1/68
CPC分类号： C12Q1/6893 , A61K39/012 , A61K2039/552 , C07K14/455 , Y02A50/489
摘要： The present invention discloses a vaccine that provides protection to turkeys from coccidiosis, and methods of making and using the vaccine alone, or in combinations with other protective agents. In addition, the present invention discloses PCR primer sets that are useful in identifying the species of Eimeria in a biological sample.
摘要翻译： 本发明公开了一种疫苗，其提供来自球虫病的火鸡的保护，以及单独制备和使用疫苗或与其它保护剂组合的方法。 此外，本发明公开了可用于鉴定生物样品中艾美球虫种类的PCR引物组。
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公开(公告)号：US20100008948A1
公开(公告)日：2010-01-14
申请号：US12539249
申请日：2009-08-11
IPC分类号： A61K39/245 , C12N7/01 , A61K39/12 , A61P31/22
CPC分类号： A61K39/12 , A61K2039/5256 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N15/86 , C12N2710/16334 , C12N2710/16343 , C12N2760/18134
摘要： The present invention provides a novel avian herpesvirus (NAHV) vector and recombinant vaccines made therefrom that are useful to immunize avian species against Marek's disease, infectious laryngotracheitis and Newcastle disease. Methods of immunizing an avian species against Marek's disease, infectious laryngotracheitis and Newcastle disease are also provided.
摘要翻译： 本发明提供了一种新型鸟类疱疹病毒（NAHV）载体和由其制备的重组疫苗，其可用于免疫禽类针对马立克氏病，感染性喉气管炎和新城疫病。 还提供了免疫禽类针对马立克氏病，感染性喉气管炎和新城疫的方法。
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公开(公告)号：US08252292B2
公开(公告)日：2012-08-28
申请号：US12616341
申请日：2009-11-11
申请人： Steve Hewart Fitz-Coy , Gamini Saman Kumara Withanage , Alexandria Louise McGowan , Stephanie M. Cook
发明人： Steve Hewart Fitz-Coy , Gamini Saman Kumara Withanage , Alexandria Louise McGowan , Stephanie M. Cook
IPC分类号： A61K39/012 , A61K39/00 , A61K39/002 , C12N1/00 , C12N1/36
CPC分类号： C12Q1/6893 , A61K39/012 , A61K2039/552 , C07K14/455 , Y02A50/489
摘要： The present invention discloses a vaccine that provides protection to turkeys from coccidiosis, and methods of making and using the vaccine alone, or in combinations with other protective agents. In addition, the present invention discloses PCR primer sets that are useful in identifying the species of Eimeria in a biological sample.
摘要翻译： 本发明公开了一种疫苗，其提供来自球虫病的火鸡的保护，以及单独制备和使用疫苗或与其它保护剂组合的方法。 此外，本发明公开了可用于鉴定生物样品中艾美球虫种类的PCR引物组。
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公开(公告)号：US07314715B2
公开(公告)日：2008-01-01
申请号：US11126465
申请日：2005-05-11
IPC分类号： C12Q1/68
CPC分类号： A61K39/12 , A61K2039/5256 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N15/86 , C12N2710/16334 , C12N2710/16343 , C12N2760/18134
摘要： The present invention provides a novel avian herpesvirus (NAHV) vector and recombinant vaccines made therefrom that are useful to immunize avian species against Marek's disease, infectious laryngotracheitis and Newcastle disease. Methods of immunizing an avian species against Marek's disease, infectious laryngotracheitis and Newcastle disease are also provided.
摘要翻译： 本发明提供了一种新型鸟类疱疹病毒（NAHV）载体和由其制备的重组疫苗，其可用于免疫禽类针对马立克氏病，感染性喉气管炎和新城疫病。 还提供了免疫禽类针对马立克氏病，感染性喉气管炎和新城疫的方法。
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公开(公告)号：US06913751B2
公开(公告)日：2005-07-05
申请号：US09881457
申请日：2001-06-14
IPC分类号： A61K39/00 , C07K14/03 , C07K14/055 , C07K14/08 , C07K14/125 , C07K14/165 , C12N7/04 , C12N15/869 , A61K39/12
CPC分类号： C12N7/00 , A61K39/00 , C07K14/005 , C12N15/86 , C12N2710/16322 , C12N2710/16343 , C12N2710/16361 , C12N2710/16422 , C12N2760/18122 , C12N2770/20022
摘要： The present invention provides a novel avian herpesvirus (NAHV) vector and recombinant vaccines made therefrom that are useful to immunize avian species against Marek's disease, infectious laryngotracheitis and Newcastle disease. Methods of immunizing an avian species against Marek's disease, infectious laryngotracheitis and Newcastle disease are also provided.
摘要翻译： 本发明提供了一种新型鸟类疱疹病毒（NAHV）载体和由其制备的重组疫苗，其可用于免疫禽类针对马立克氏病，感染性喉气管炎和新城疫病。 还提供了免疫禽类针对马立克氏病，感染性喉气管炎和新城疫的方法。
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