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1.发明授权公开(公告)号：US11807857B2
公开(公告)日：2023-11-07
申请号：US15321969
申请日：2015-06-24
发明人： Michael Bennett , Bill L. Hendrix , Alberto Iandolino , Yao Luo , Wei Zheng
IPC分类号： C12N15/82
CPC分类号： C12N15/8206 , C12N15/8218 , C12N15/8274 , C12N15/8281 , C12N15/8282 , C12N15/8283 , C12N15/8285 , C12N15/8286
摘要： Transfection of plant cells with dsRNA through foliar application encounters cuticle, cell wall and plasmalemma three major barriers. We developed cationic polymer and sugar based formulations and protocols that can effectively deliver dsRNA into plant cells resulted in gene silencing. This disclosure covers the novel methods to deliver dsRNA into plant suspension cells with ‘one step’ treatment and plant foliar cells with ‘one step’ topical application.
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2.发明申请公开(公告)号：US20180119160A1
公开(公告)日：2018-05-03
申请号：US15808294
申请日：2017-11-09
发明人： Jill Deikman , Steven H. Schwartz , Wei Zheng , Suzan Herma Elisabeth Johanna Gabriels , Michelle C. Hresko , Xiangqian Li , Nengbing Tao , Deryck J. Williams , Hui Xiong
IPC分类号： C12N15/82
CPC分类号： C12N15/8218 , C12N15/8249 , C12N15/8266 , C12N15/8279 , C12N15/8282
摘要： The present invention provides novel compositions for use to enhance crop performance. Specifically, the present invention provides for delayed senescence and/or improved yield enhancement in various crops. The present invention also provides for combinations of compositions and methods that provide for delayed senescence and/or improved yield.
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公开(公告)号：US20160230183A1
公开(公告)日：2016-08-11
申请号：US14998728
申请日：2016-02-08
发明人： Mark Scott Abad , Jeffery E. Ahrens , Alice Clara Augustine , Erin Bell , Robert J. Bensen , Srikanth Venkatachalayya , Paolo Castiglioni , R. Eric Cerny , Jaishree M. Chittoor-Vijayanath , Maureen Daley , Jill Deikman , Molian Deng , Todd DeZwaan , Stephen Duff , Michael D. Edgerton , Bradon J. Fabbri , Jason Fenner , Karen Gabbert , Meghan Galligan Donnarummo , Garrett J. Lee , Barry S. Goldman , Deborah J. Hawkins , Steve He , Xianfeng Chen , Balasulojini Karunanandaa , Paul Loida , Savitha Madappa , Robert J. Meister , Ming Peng , Donald E. Nelson , Anand Pandravada , Obed Patty , Marie Petracek , Rajani Monnanda Somaiah , Monica P. Ravanello , Richard Johnson , Thomas G. Ruff , Rick A. Sanders , Beth Savidge , Steven H. Schwartz , Shobha Char , Padmini Sudarshana , Jindong Sun , Rebecca L. Thompson-Mize , Virginia Ursin , Dale V. Val , Tymagondlu V. Venkatesh , Kammaradi Vidya , K. Vijayalakshmi , Todd C. Weber , Jingrui Wu , Wei Zheng , Zhidong Xie , Dhanalakshmi Ramachandra
CPC分类号： C12N15/8273 , A01H1/02 , C12N15/8241 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12Q1/6895 , C12Q2600/13 , Y02A40/146
摘要： This invention provides recombinant DNA constructs, transgenic plant nuclei and cells with such recombinant DNA construct for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
摘要翻译： 本发明提供重组DNA构建体，转基因植物核和具有这样的重组DNA构建体的细胞，用于表达可用于赋予转基因作物植物增强的农艺性状的蛋白质。 本发明还提供包含转基因植物细胞的转基因植物和后代种子，其中植物被选择用于具有增强的性状，所述性状选自由增强的水利用效率，增强的耐寒性，增加的产量，增强的氮利用效率，增强的氮利用效率， 种子蛋白和增强种子油。 还公开了用于制备具有增强特征的转基因种子和植物的方法。
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公开(公告)号：US20200208167A1
公开(公告)日：2020-07-02
申请号：US16602981
申请日：2020-01-09
发明人： Mark Scott Abad , Jeffrey E. Ahrens , Alice Clara Augustine , Erin Bell , Robert J. Bensen , Paolo Castiglioni , Richard Eric Cerny , Shobha Char , Xianfeng Chen , Jaishree M. Chittoor-Vijayanath , Maureen Daley , Jilll Deikman , Molian Deng , Todd DeZwaan , Stephen Duff , Michael D. Edgerton , Bradon J. Fabbri , Jason Fenner , Karen Gabbert , Barry S. Goldman , Deborah J. Hawkins , Steve He , Richard Johnson , Balasulojini Karunanandaa , Garrett J. Lee , Paul Loida , Savitha Madappa , Robert J. Meister , Donald E. Nelson , Anand Pandravada , Obed Patty , Ming Peng , Marie Petracek , Rajani Monnanda Somaiah , Dhanalakshmi Ramachandra , Monica P. Ravanello , Thomas G. Ruff , Rick A Sanders , Beth Savidge , Steven H. Schwartz , Padmini Sudarshana , Jindong Sun , Rebecca L. Thompson-Mize , Virginia Ursin , Dale L. Val , Srikanth Venkatachalayya , Tymagondlu V. Venkatesh , Kammaradi Vidya , K. Vijayalakshmi , Todd C. Weber , Jingrui Wu , Zhidong Xie , Wei Zheng
IPC分类号： C12N15/82 , A01H1/02 , C12Q1/6895
摘要： This invention provides recombinant DNA constructs, transgenic plant nuclei and cells with such recombinant DNA construct for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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5.发明申请公开(公告)号：US20170130237A1
公开(公告)日：2017-05-11
申请号：US15321969
申请日：2015-06-24
发明人： Michael Bennett , Bill L. Hendrix , Alberto landolino , Yao Luo , Wei Zheng
IPC分类号： C12N15/82
CPC分类号： C12N15/8206 , A01N43/90 , C12N15/8218 , C12N15/8274 , C12N15/8281 , C12N15/8282 , C12N15/8283 , C12N15/8285 , C12N15/8286
摘要： Transfection of plant cells with dsRNA through foliar application encounters cuticle, cell wall and plasmalemma three major barriers. We developed cationic polymer and sugar based formulations and protocols that can effectively deliver dsRNA into plant cells resulted in gene silencing. This disclosure covers the novel methods to deliver dsRNA into plant suspension cells with ‘one step’ treatment and plant foliar cells with ‘one step’ topical application.
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公开(公告)号：US11479783B2
公开(公告)日：2022-10-25
申请号：US16602981
申请日：2020-01-09
发明人： Mark Scott Abad , Jeffrey E. Ahrens , Alice Clara Augustine , Erin Bell , Robert J. Bensen , Paolo Castiglioni , Richard Eric Cerny , Shobha Char , Xianfeng Chen , Jaishree M. Chittoor-Vijayanath , Maureen Daley , Jill Deikman , Molian Deng , Todd DeZwaan , Stephen Duff , Michael D. Edgerton , Bradon J. Fabbri , Jason Fenner , Karen Gabbert , Barry S. Goldman , Deborah J. Hawkins , Steve He , Richard Johnson , Balasulojini Karunanandaa , Garrett J. Lee , Paul Loida , Savitha Madappa , Robert J. Meister , Donald E. Nelson , Anand Pandravada , Obed Patty , Ming Peng , Marie Petracek , Rajani Monnanda Somaiah , Dhanalakshmi Ramachandra , Monica P. Ravanello , Thomas G. Ruff , Rick A. Sanders , Beth Savidge , Steven H. Schwartz , Padmini Sudarshana , Jindong Sun , Rebecca L. Thompson-Mize , Virginia Ursin , Dale L. Vai , Srikanth Venkatachalayya , Tymagondlu V. Venkatesh , Kammaradi Vidya , K. Vijayalakshmi , Todd C. Weber , Jingrui Wu , Zhidong Xie , Wei Zheng
IPC分类号： C12N15/82 , A01H1/02 , C12Q1/6895
摘要： This invention provides recombinant DNA constructs, transgenic plant nuclei and cells with such recombinant DNA construct for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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7.发明授权公开(公告)号：US10435702B2
公开(公告)日：2019-10-08
申请号：US15808294
申请日：2017-11-09
发明人： Jill Deikman , Steven H. Schwartz , Wei Zheng , Suzan Herma Elisabeth Johanna Gabriels , Michelle C. Hresko , Xiangqian Li , Nengbing Tao , Deryck J. Williams , Hui Xiong
IPC分类号： C12N15/82
摘要： The present invention provides novel compositions for use to enhance crop performance. Specifically, the present invention provides for delayed senescence and/or improved yield enhancement in various crops. The present invention also provides for combinations of compositions and methods that provide for delayed senescence and/or improved yield.
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公开(公告)号：US20180258442A1
公开(公告)日：2018-09-13
申请号：US15932378
申请日：2018-02-20
发明人： Mark Scott Abad , Thomas R. Adams , Julie A. Alvarez , Mahindra Anuradha , Alice Clara Augustine , Erin Bell , Kristen A. Bennett , Robert J. Bensen , Paolo Castiglioni , Richard Eric Cerny , Xianfeng Chen , Jaishree M. Chittoor-Vijayanath , Farah Deeba , Jill Dcikman , Molian Deng , Stephen Duff , Bradon J. Fabbri , Jason Fenner , Mary Fernandes , Karen Gabbert , Barry S. Goldman , Deborah J. Hawkins , Jacqueline E. Heard , Balasulojini Karunanandaa , Dangyang Ke , John R. Ledeaux , Garrett J. Lee , Savitha Madappa , Donald E. Nelson , Obed Patty , Badami S. Pratesh , Qungang Qi , Ramachandra Dhanalakshmi , G. Ramamohan , Thomas G. Ruff , Rick A. Sanders , Sangeetha Singh , Thomas J. Savage , Beth Savidge , Char Shobha , Rajani Monnanda Somaiah , Padmini Sudarshana , Sreekanta Suma , Jindong Sun , Rebecca L. Thompson-Mize , Dale L. Val , Srikanth Venkatachalayya , Tymagondlu V. Venkatesh , Kammaradi Vidya , Jingrui Wu , Zhidong Xie , Nanfei Xu , Wei Zheng , Rajani Monnanda Somaiah , Meghan Galligan Donnarummo
IPC分类号： C12N15/82 , A01H1/02 , C12Q1/6895
CPC分类号： C12N15/8275 , A01H1/02 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8273 , C12N15/8274 , C12Q1/6895 , C12Q2600/13 , C12Q2600/158 , Y02A40/146
摘要： This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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公开(公告)号：US20150113676A1
公开(公告)日：2015-04-23
申请号：US14121611
申请日：2014-09-24
发明人： Mark Scott Abad , Thomas R. Adams , Julie A. Alvarez , Mahindra Anuradha , Alice Clara Augustine , Erin Bell , Kristen A. Bennett , Robert J. Bensen , Paolo Castiglioni , Richard E. Cerny , Xianfeng Chen , Jaishree M. Chittoor-Vijayanath , Farah Deeba , Jill Deikman , Molian Deng , Meghan Galligan-Donnarummo , Stephen Duff , Bradon J. Fabbri , Jason Fenner , Mary Fernandes , Karen Gabbert , Barry S. Goldman , Deborah J. Hawkins , Jacqueline E. Heard , Balasulojini Karunanandaa , Dangyang Ke , John R. Ledeaux , Garrett J. Lee , Savitha Madappa , Donald E. Nelson , Obed Patty , Badami S. Pranesh , Qungang Qi , Ramachandra Dhanalakshmi , G. Ramamohan , Thomas G. Ruff , Rick A. Sanders , Sangeetha Singh , Thomas J. Savage , Beth Savidge , Char Shobha , Rajani Monnanda Somaiah , Padmini Sudarshana , Sreekanta Navarathna Suma , Jindong Sun , Rebecca L. Thompson-Mize , Dale L. Val , Srikanth Venkatachalayya , Tymagondlu V. Venkatesh , Kammaradi Vidya , Jingrui Wu , Zhidong Xie , Nanfei Xu , Wei Zheng , Rajani Monnanda Somaiah
CPC分类号： C12N15/8275 , A01H1/02 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8273 , C12N15/8274 , C12Q1/6895 , C12Q2600/13 , C12Q2600/158 , Y02A40/146
摘要： This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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公开(公告)号：US20180245095A1
公开(公告)日：2018-08-30
申请号：US15732622
申请日：2017-12-05
发明人： Mark Scott Abad , Jeffrey E. Ahrens , Alice Clara Augustine , Erin Bell , Robert J. Bensen , Srikanth Venkatachalayya , Paolo Castiglioni , Richard Eric Cerny , Jaishree M. Chittoor-Vijayanath , Maureen Daley , Jill Deikman , Molian Deng , Todd DeZwaan , Stephen Duff , Michael D. Edgerton , Bradon J. Fabbri , Jason Fenner , Karen Gabbert , Garrett J. Lee , Barry S. Goldman , Deborah J. Hawkins , Steve He , Xianfeng Chen , Balasulojini Karunanandaa , Paul Loida , Savitha Madappa , Robert J. Meister , Ming Peng , Donald E. Nelson , Anand Pandravada , Obed Patty , Marie Petracek , Rajani Monnanda Somaiah , Monica P. Ravanello , Richard Johnson , Thomas G. Ruff , Rick A. Sanders , Beth Savidge , Steven H. Schwarts , Shobha Char , Padmini Sudarshana , Jindong Sun , Rebecca L. Thompson-Mize , Virginia Ursin , Dale L. Val , Tymagondlu V. Venkatesh , Kammaradi Vidya , K. Vijayalakshmi , Todd C. Weber , Jingrui Wu , Wei Zheng , Zhidong Xie , Dhanalaksmi Ramachandra
IPC分类号： C12N15/82 , A01H1/02 , C12Q1/6895
摘要： This invention provides recombinant DNA constructs, transgenic plant nuclei and cells with such recombinant DNA construct for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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