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公开(公告)号：US10570414B2
公开(公告)日：2020-02-25
申请号：US15348839
申请日：2016-11-10
Applicant: Monsanto Technology LLC
Inventor： Edwards Allen , William P. Donovan , Gregory R. Heck , James K. Roberts , Virginia Ursin , Yuanji Zhang
IPC: C12N15/82 , A01N63/02 , C12N15/113
Abstract: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention. This invention further provides a method of suppressing at least one target gene of an invertebrate pest of a plant or of a symbiont associated with the invertebrate, including providing a plant including the non-natural transgenic plant cell of this invention, wherein the invertebrate is the invertebrate pest, the recombinant DNA is transcribed in the non-natural transgenic plant cell to the recombinant miRNA precursor, and when the invertebrate pest ingests the recombinant miRNA precursor, the at least one target gene is suppressed.
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公开(公告)号：US20130165498A1
公开(公告)日：2013-06-27
申请号：US13746500
申请日：2013-01-22
Applicant: Monsanto Technology LLC
Inventor： Edwards Allen , William P. Donovan , Gregory R. Heck , James K. Roberts , Virginia Ursin , Yuanji Zhang
IPC: C12N15/113
CPC classification number: C12N15/8286 , A01N63/02 , C12N15/113 , C12N15/8285 , C12N2310/14 , C12N2310/141 , C12N2310/531 , Y02A40/162 , Y02A40/164
Abstract: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention. This invention further provides a method of suppressing at least one target gene of an invertebrate pest of a plant or of a symbiont associated with the invertebrate, including providing a plant including the non-natural transgenic plant cell of this invention, wherein the invertebrate is the invertebrate pest, the recombinant DNA is transcribed in the non-natural transgenic plant cell to the recombinant miRNA precursor, and when the invertebrate pest ingests the recombinant miRNA precursor, the at least one target gene is suppressed.
Abstract translation: 本发明提供具有抗无脊椎害虫的植物。 更具体地，本发明公开了一种非天然转基因植物细胞，其在植物中表达至少一种无脊椎动物miRNA，用于抑制无脊椎害虫或与无脊椎害虫相关的共生体的靶基因。 还提供了用于在植物中表达至少一种无脊椎动物miRNA的重组DNA构建体，包含本发明的非天然转基因植物细胞的非天然转基因植物，从非天然转基因植物细胞生长的非天然转基因植物 以及由非天然转基因植物产生的非天然转基因种子，以及由本发明的非天然转基因植物细胞，植物或种子产生的商品。 本发明还提供了抑制植物无脊椎动物害虫或与无脊椎动物相关共生体的至少一种目标基因的方法，包括提供包含本发明的非天然转基因植物细胞的植物，其中无脊椎动物是 无脊椎动物害虫，重组DNA在非天然转基因植物细胞中转录至重组miRNA前体，当无脊椎害虫摄入重组miRNA前体时，抑制至少一种靶基因。
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公开(公告)号：US20200208167A1
公开(公告)日：2020-07-02
申请号：US16602981
申请日：2020-01-09
Applicant: Monsanto Technology LLC
Inventor： Mark Scott Abad , Jeffrey E. Ahrens , Alice Clara Augustine , Erin Bell , Robert J. Bensen , Paolo Castiglioni , Richard Eric Cerny , Shobha Char , Xianfeng Chen , Jaishree M. Chittoor-Vijayanath , Maureen Daley , Jilll Deikman , Molian Deng , Todd DeZwaan , Stephen Duff , Michael D. Edgerton , Bradon J. Fabbri , Jason Fenner , Karen Gabbert , Barry S. Goldman , Deborah J. Hawkins , Steve He , Richard Johnson , Balasulojini Karunanandaa , Garrett J. Lee , Paul Loida , Savitha Madappa , Robert J. Meister , Donald E. Nelson , Anand Pandravada , Obed Patty , Ming Peng , Marie Petracek , Rajani Monnanda Somaiah , Dhanalakshmi Ramachandra , Monica P. Ravanello , Thomas G. Ruff , Rick A Sanders , Beth Savidge , Steven H. Schwartz , Padmini Sudarshana , Jindong Sun , Rebecca L. Thompson-Mize , Virginia Ursin , Dale L. Val , Srikanth Venkatachalayya , Tymagondlu V. Venkatesh , Kammaradi Vidya , K. Vijayalakshmi , Todd C. Weber , Jingrui Wu , Zhidong Xie , Wei Zheng
IPC: C12N15/82 , A01H1/02 , C12Q1/6895
Abstract: This invention provides recombinant DNA constructs, transgenic plant nuclei and cells with such recombinant DNA construct for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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公开(公告)号：US20170283780A1
公开(公告)日：2017-10-05
申请号：US15497058
申请日：2017-04-25
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Virginia Ursin , Fenggao Dong , Byron Froman , Thomas J. La Rosa , Steven E. Screen , Jennifer C. Simmons
CPC classification number: C12N9/0004 , C12N15/8247 , C12P7/6427
Abstract: The invention relates generally to methods and compositions concerning desaturase enzymes that modulate the number and location of double bonds in long chain poly-unsaturated fatty acids (LC-PUFA's). In particular, the invention relates to methods and compositions for improving omega-3 fatty acid profiles in plant products and parts using desaturase enzymes and nucleic acids encoding for such enzymes. In particular embodiments, the desaturase enzymes are Primula Δ6-desaturases. Also provided are improved soybean oil compositions having SDA and a beneficial overall content of omega-3 fatty acids relative to omega-6 fatty acids.
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公开(公告)号：US20160230183A1
公开(公告)日：2016-08-11
申请号：US14998728
申请日：2016-02-08
Applicant: Monsanto Technology LLC
Inventor： Mark Scott Abad , Jeffery E. Ahrens , Alice Clara Augustine , Erin Bell , Robert J. Bensen , Srikanth Venkatachalayya , Paolo Castiglioni , R. Eric Cerny , Jaishree M. Chittoor-Vijayanath , Maureen Daley , Jill Deikman , Molian Deng , Todd DeZwaan , Stephen Duff , Michael D. Edgerton , Bradon J. Fabbri , Jason Fenner , Karen Gabbert , Meghan Galligan Donnarummo , Garrett J. Lee , Barry S. Goldman , Deborah J. Hawkins , Steve He , Xianfeng Chen , Balasulojini Karunanandaa , Paul Loida , Savitha Madappa , Robert J. Meister , Ming Peng , Donald E. Nelson , Anand Pandravada , Obed Patty , Marie Petracek , Rajani Monnanda Somaiah , Monica P. Ravanello , Richard Johnson , Thomas G. Ruff , Rick A. Sanders , Beth Savidge , Steven H. Schwartz , Shobha Char , Padmini Sudarshana , Jindong Sun , Rebecca L. Thompson-Mize , Virginia Ursin , Dale V. Val , Tymagondlu V. Venkatesh , Kammaradi Vidya , K. Vijayalakshmi , Todd C. Weber , Jingrui Wu , Wei Zheng , Zhidong Xie , Dhanalakshmi Ramachandra
CPC classification number: C12N15/8273 , A01H1/02 , C12N15/8241 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12Q1/6895 , C12Q2600/13 , Y02A40/146
Abstract: This invention provides recombinant DNA constructs, transgenic plant nuclei and cells with such recombinant DNA construct for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
Abstract translation: 本发明提供重组DNA构建体，转基因植物核和具有这样的重组DNA构建体的细胞，用于表达可用于赋予转基因作物植物增强的农艺性状的蛋白质。 本发明还提供包含转基因植物细胞的转基因植物和后代种子，其中植物被选择用于具有增强的性状，所述性状选自由增强的水利用效率，增强的耐寒性，增加的产量，增强的氮利用效率，增强的氮利用效率， 种子蛋白和增强种子油。 还公开了用于制备具有增强特征的转基因种子和植物的方法。
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Patent Agency Ranking
公开(公告)号：US11479783B2
公开(公告)日：2022-10-25
申请号：US16602981
申请日：2020-01-09
Applicant: Monsanto Technology LLC
Inventor： Mark Scott Abad , Jeffrey E. Ahrens , Alice Clara Augustine , Erin Bell , Robert J. Bensen , Paolo Castiglioni , Richard Eric Cerny , Shobha Char , Xianfeng Chen , Jaishree M. Chittoor-Vijayanath , Maureen Daley , Jill Deikman , Molian Deng , Todd DeZwaan , Stephen Duff , Michael D. Edgerton , Bradon J. Fabbri , Jason Fenner , Karen Gabbert , Barry S. Goldman , Deborah J. Hawkins , Steve He , Richard Johnson , Balasulojini Karunanandaa , Garrett J. Lee , Paul Loida , Savitha Madappa , Robert J. Meister , Donald E. Nelson , Anand Pandravada , Obed Patty , Ming Peng , Marie Petracek , Rajani Monnanda Somaiah , Dhanalakshmi Ramachandra , Monica P. Ravanello , Thomas G. Ruff , Rick A. Sanders , Beth Savidge , Steven H. Schwartz , Padmini Sudarshana , Jindong Sun , Rebecca L. Thompson-Mize , Virginia Ursin , Dale L. Vai , Srikanth Venkatachalayya , Tymagondlu V. Venkatesh , Kammaradi Vidya , K. Vijayalakshmi , Todd C. Weber , Jingrui Wu , Zhidong Xie , Wei Zheng
IPC: C12N15/82 , A01H1/02 , C12Q1/6895
Abstract: This invention provides recombinant DNA constructs, transgenic plant nuclei and cells with such recombinant DNA construct for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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公开(公告)号：US09528121B2
公开(公告)日：2016-12-27
申请号：US13746500
申请日：2013-01-22
Applicant: Monsanto Technology LLC
Inventor： Edwards Allen , William P. Donovan , Gregory R. Heck , James K. Roberts , Virginia Ursin , Yuanji Zhang
IPC: A01H1/00 , C12N15/82 , C12N15/87 , A01N63/02 , C12N15/113
CPC classification number: C12N15/8286 , A01N63/02 , C12N15/113 , C12N15/8285 , C12N2310/14 , C12N2310/141 , C12N2310/531 , Y02A40/162 , Y02A40/164
Abstract: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention. This invention further provides a method of suppressing at least one target gene of an invertebrate pest of a plant or of a symbiont associated with the invertebrate, including providing a plant including the non-natural transgenic plant cell of this invention, wherein the invertebrate is the invertebrate pest, the recombinant DNA is transcribed in the non-natural transgenic plant cell to the recombinant miRNA precursor, and when the invertebrate pest ingests the recombinant miRNA precursor, the at least one target gene is suppressed.
Abstract translation: 本发明提供具有抗无脊椎害虫的植物。 更具体地，本发明公开了一种非天然转基因植物细胞，其在植物中表达至少一种无脊椎动物miRNA，用于抑制无脊椎害虫或与无脊椎害虫相关的共生体的靶基因。 还提供了用于在植物中表达至少一种无脊椎动物miRNA的重组DNA构建体，包含本发明的非天然转基因植物细胞的非天然转基因植物，从非天然转基因植物细胞生长的非天然转基因植物 以及由非天然转基因植物产生的非天然转基因种子，以及由本发明的非天然转基因植物细胞，植物或种子产生的商品。 本发明还提供一种抑制植物无脊椎动物害虫或与无脊椎动物相关共生体的至少一种靶基因的方法，包括提供包含本发明非天然转基因植物细胞的植物，其中无脊椎动物是 无脊椎动物害虫，重组DNA在非天然转基因植物细胞中转录至重组miRNA前体，当无脊椎害虫摄入重组miRNA前体时，抑制至少一种靶基因。
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公开(公告)号：US20160272994A1
公开(公告)日：2016-09-22
申请号：US14999032
申请日：2016-03-21
Applicant: Monsanto Technology LLC
Inventor： Mark Scott Abad , Thandoni Rao Ambika , Erin Bell , Kraig Brustad , R. Eric Cerny , Shobha Char , Jaishree M. Chittoor-Vijayanath , Paul S. Chomet , Julie Davis , Molian Deng , Todd DeZwaan , Michael D. Edgerton , Karen Gabbert , Barry S. Goldman , Brian Hauge , Steve He , Jacqueline E. Heard , Alberto Iandolino , Ping Li , Linda L. Lutfiyya , Savitha Madappa , Brad McDill , Robert J. Meister , Peter Morrell , Anil Neelam , Marie Petracek , John Pitkin , M. S. Rajani , Dhanalakshmi Ramachandra , Monica P. Ravanello , Maria F. Rodriguez , Thomas G. Ruff , Sangeetha Singh , Virginia Ursin , Tymagondlu V. Venkatesh , Kammaradi R. Vidya , K. Vijayalakshmi , Xiaoyun Wu , Jianmin Zhao
IPC: C12N15/82 , C07K14/415 , G01N33/68 , C12Q1/68
CPC classification number: C12N15/8273 , C07K14/415 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8274 , C12N15/8275 , C12Q1/6895 , C12Q2600/13 , G01N33/68 , G01N2333/415 , Y02A40/146
Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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公开(公告)号：US20130338386A1
公开(公告)日：2013-12-19
申请号：US13770929
申请日：2013-02-19
Applicant: Monsanto Technology LLC
Inventor： Virginia Ursin , Byron Froman , A. J. Nava , Jennifer Simmons
IPC: C12P7/64
CPC classification number: C12P7/6427 , C12N9/0083 , C12N15/8247
Abstract: The invention relates generally to the expression of desaturase enzymes in transgenic corn plants and compositions derived therefrom. In particular, the invention relates to the production of oils with improved omega-3 fatty acid profiles in corn plants and the seed oils produced thereby. Such oils may contain stearidonic acid, which is not naturally found in corn plants and has been shown to have beneficial effects on health.
Abstract translation: 本发明一般涉及转基因玉米植物中去饱和酶的表达及其衍生物。 特别地，本发明涉及在玉米植物中生产具有改进的ω-3脂肪酸谱的油以及由此生产的种子油。 这样的油可以含有十八碳四烯酸，其在玉米植物中不是天然存在的，并且已经显示出对健康有益的效果。
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公开(公告)号：US10174297B2
公开(公告)日：2019-01-08
申请号：US15497058
申请日：2017-04-25
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Virginia Ursin , Fenggao Dong , Byron Froman , Thomas J. La Rosa , Steven E. Screen , Jennifer C. Simmons
Abstract: The invention relates generally to methods and compositions concerning desaturase enzymes that modulate the number and location of double bonds in long chain poly-unsaturated fatty acids (LC-PUFA's). In particular, the invention relates to methods and compositions for improving omega-3 fatty acid profiles in plant products and parts using desaturase enzymes and nucleic acids encoding for such enzymes. In particular embodiments, the desaturase enzymes are Primula Δ6-desaturases. Also provided are improved soybean oil compositions having SDA and a beneficial overall content of omega-3 fatty acids relative to omega-6 fatty acids.
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