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公开(公告)号:US5294546A
公开(公告)日:1994-03-15
申请号:US799881
申请日:1991-11-29
CPC分类号: C12N1/20 , C12N1/38 , C12P19/02 , C12P19/04 , Y10S435/921 , Y10S435/922 , Y10S435/923 , Y10S435/924 , Y10S435/938 , Y10S435/944
摘要: A method of producing a growth promoting factor for Bifidobacterium species from lactose which comprises contacting lactose with resting cells of a lactose-utilizing yeast strain having activity to rearrange lactose to galacto-oligosaccharides.
摘要翻译: 一种从乳糖生产双歧杆菌物种生长促进因子的方法,其包括将乳糖与具有将乳糖重排乳糖寡糖的活性的乳糖利用酵母菌株的静息细胞接触。
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2.
公开(公告)号:US4886749A
公开(公告)日:1989-12-12
申请号:US54975
申请日:1987-05-28
CPC分类号: C12N9/93 , C12P19/36 , Y10S435/822 , Y10S435/832
摘要: A process for producing diadenosine tetraphosphate or derivatives thereof in very high yields with little formation of undesired by-products is disclosed. The process comprises reacting adenosine-5'-triphosphate or a derivative thereof with an amino acid under the catalytic action of an aminoacyl-tRNA synthetase in the presence of an enzyme that converts adenosine-5'-diphosphate to adenosine-5'-triphosphate. The formation of by-products can be substantially completely inhibited if the last-mentioned enzyme is used in combination with an enzyme that converts adenosine-5'-monophosphate to adenosine-5'-diphosphate.
摘要翻译: 公开了以非常高的产率生产二腺苷四磷酸或其衍生物的方法,几乎没有形成不需要的副产物。 该方法包括在氨基-5'-二磷酸腺苷转化为腺苷-5'-三磷酸的酶存在下,在氨基-tRNA合成酶的催化作用下使腺苷-5'-三磷酸或其衍生物与氨基酸反应。 如果最后提到的酶与将腺苷-5'-单磷酸腺苷转化为腺苷-5'-二磷酸的酶组合使用,副产物的形成可以基本上完全被抑制。
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3.
公开(公告)号:US5401725A
公开(公告)日:1995-03-28
申请号:US140961
申请日:1993-10-25
IPC分类号: A61K31/70 , A61K31/7042 , A61K31/7052 , A61K31/7076 , A61P9/00 , A61P27/02 , A61P29/00 , A61P35/00 , A61P37/00 , C07H19/20
摘要: The present invention provides, as a noval and safe vascularization inhibitor having an excellent effect, a vascularization inhibitor which is characterized by containing, as the effective ingredient, 3-phosphoadenosine 5'-phosphosulfate or adenosine 5'-phosphosulfate which is expressed by the following general formula: ##STR1## (where, x represents a phosphate or hydroxide group) or a pharmaceutically allowable salt thereof.
摘要翻译: 本发明提供作为具有优异效果的noval和安全的血管形成抑制剂,其特征在于含有以下表达的3-磷酸腺苷5'-磷酸硫酸或腺苷5'-磷酸硫酸的作为有效成分的血管抑制剂 通式:
(其中,x表示磷酸盐或氢氧基)或其药学上可允许的盐。 -
公开(公告)号:US6146862A
公开(公告)日:2000-11-14
申请号:US75194
申请日:1998-05-11
申请人: Shido Kawase , Hitoshi Kondo , Munehiko Dombou
发明人: Shido Kawase , Hitoshi Kondo , Munehiko Dombou
IPC分类号: C12N15/09 , C07H21/04 , C12N1/21 , C12N9/02 , C12N15/00 , C12N15/31 , C12R1/07 , C12R1/19 , C12N1/14 , C12N1/20
CPC分类号: C12N9/0051
摘要: The present invention provides a gene derived from a thermophilic Bacillus, comprising the nucleotide sequence of SEQ ID No.2 and encoding a thermostable diaphorase comprising the amino acid sequence of SEQ ID No.1, a recombinant vector possessing the gene, a transformant with the recombinant vector and a process for producing the thermostable diaphorase by using the transformant.
摘要翻译: 本发明提供源自嗜热芽孢杆菌的基因,其包含SEQ ID No.2的核苷酸序列,并编码包含SEQ ID No.1的氨基酸序列的热稳定性心肌黄酶,具有该基因的重组载体,具有该基因的转化体 重组载体和通过使用转化体产生热稳定性黄体变酶的方法。
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