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公开(公告)号：US5098887A
公开(公告)日：1992-03-24
申请号：US659432
申请日：1991-02-26
IPC分类号： C12N9/99 , A61K38/00 , A61K38/55 , A61P9/12 , C07K1/20 , C07K7/06 , C07K14/195 , C07K14/41 , C07K14/81 , C12N9/04 , C12P21/02 , C12R1/07
CPC分类号： C12N9/0006 , A61K38/00
摘要： An angiotensin converting enzyme inhibitor containing Gly-Lys-Glu-Ile-Ile-Val-Lys-Ala-Glu-Arg (SEQ ID No: 1) Gly-Lys-Met-Val-Lys-Val-Val-Ser-Trp-Tyr (SEQ ID No: 2) or Ala-Tyr-Ile-Ala-Ser-Lys-Gly-Leu (SEQ ID No: 3) as an active component.
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公开(公告)号：US5322782A
公开(公告)日：1994-06-21
申请号：US963255
申请日：1992-10-19
CPC分类号： C12P41/00 , C12P7/40 , Y10S435/877
摘要： Optically active .beta.-halolactic acids can be produced by contacting an .alpha.,.beta.-dihalopropionic acid with 2-halo acid dehalogenase. When the pH of the reaction system is above 9, this process gives optically active glycidic acid. Treatment of the optically active .beta.-halolactic acid thus obtained with an alkali also gives optically active glycidic acid.
摘要翻译： 可以通过使α，β-二卤代丙酸与2-卤代脱卤素酶接触来制备光学活性的β-阿拉伯糖酸。 当反应体系的pH高于9时，该方法得到光学活性的缩水甘油酸。 用碱处理由此获得的光学活性β-卤代乳酸也可得到光学活性的缩水甘油酸。
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公开(公告)号：US5294546A
公开(公告)日：1994-03-15
申请号：US799881
申请日：1991-11-29
CPC分类号： C12N1/20 , C12N1/38 , C12P19/02 , C12P19/04 , Y10S435/921 , Y10S435/922 , Y10S435/923 , Y10S435/924 , Y10S435/938 , Y10S435/944
摘要： A method of producing a growth promoting factor for Bifidobacterium species from lactose which comprises contacting lactose with resting cells of a lactose-utilizing yeast strain having activity to rearrange lactose to galacto-oligosaccharides.
摘要翻译： 一种从乳糖生产双歧杆菌物种生长促进因子的方法，其包括将乳糖与具有将乳糖重排乳糖寡糖的活性的乳糖利用酵母菌株的静息细胞接触。
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公开(公告)号：US5204107A
公开(公告)日：1993-04-20
申请号：US794909
申请日：1991-11-20
申请人： Ryoichi Tsurutani , Koji Kifune , Yuriko Nakamura
发明人： Ryoichi Tsurutani , Koji Kifune , Yuriko Nakamura
IPC分类号： A61K9/70 , A61K31/28 , A61K31/282 , A61K31/715 , A61K33/24 , A61K47/36 , A61K47/48 , A61P35/00 , C08B37/08
CPC分类号： A61K31/28 , A61K33/24 , A61K47/36 , A61K47/4823 , A61K47/48853 , A61K9/70
摘要： A slow-releasing composition of a platinum-containing anticancer agent comprising a platinum-containing anticancer agent bound to deacetylated chitin. The release of the platinum-containing anticancer agent is sustained for a prolonged duration of several months, thereby minimizing undesirable side effects of the platinum-containing anticancer agent.
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公开(公告)号：US5243027A
公开(公告)日：1993-09-07
申请号：US737852
申请日：1991-07-31
CPC分类号： C12N9/0006 , A61K38/00
摘要： A method of preparing an angiotensin converting enzyme inhibitor having the amino acid sequence selected from the group consisting of:Gly-Lys-Glu-Ile-Ile-Val-Lys-Ala-Glu-Arg (SEQ ID No: 1),Gly-Lys-Met-Val-Lys-Val-Val-Ser-Trp-Tyr (SEQ ID No: 2) andAla-Tyr-Ile-Ala-Ser-Lys-Gly-Leu (SEQ ID No: 3); which comprises the steps of:(a) disrupting bacteria to obtain a cell extract, wherein the disruption is at least one of mechanical and chemical disruption;(b) exposing said cell extract to an acid mixture comprising acetic acid and hydrochloric acid, wherein said acid mixture comprises acetic acid in a concentration of 0.01 to 10M and hydrochloric acid in a concentration of 1 to 100 mM, to produce an acid hydrolysate; and(c) purifying from said acid hydrolysate a peptide having the amino acid sequence selected from the group consisting of:Gly-Lys-Glu-Ile-Ile-Val-Lys-Ala-Glu-Arg (SEQ ID No: 1),Gly-Lys-Met-Val-Lys-Val-Val-Ser-Trp-Tyr (SEQ ID No: 2) andAla-Tyr-Ile-Ala-Ser-Lys-Gly-Leu (SEQ ID No: 3).
摘要翻译： 一种制备具有选自Gly-Lys-Glu-Ile-Ile-Val-Lys-Ala-Glu-Arg（SEQ ID No：1），Gly- Lys-Met-Val-Lys-Val-Val-Ser-Trp-Tyr（SEQ ID No：2）和Ala-Tyr-Ile-Ala-Ser-Lys-Gly-Leu（SEQ ID No：3）; 其包括以下步骤：（a）破坏细菌以获得细胞提取物，其中所述破坏是机械和化学破坏中的至少一种; （b）将所述细胞提取物暴露于含有乙酸和盐酸的酸混合物中，其中所述酸混合物包含浓度为0.01至10M的乙酸和浓度为1至100mM的盐酸，以产生酸水解产物; 和（c）从所述酸水解产物中纯化具有选自Gly-Lys-Glu-Ile-Ile-Val-Lys-Ala-Glu-Arg（SEQ ID No：1）的氨基酸序列的肽， Gly-Lys-Met-Val-Lys-Val-Val-Ser-Trp-Tyr（SEQ ID No：2）和Ala-Tyr-Ile-Ala-Ser-Lys-Gly-Leu（SEQ ID No：3）。
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6.发明授权Melt-processable copolyamides having aromatic amide unit and fibers prepared therefrom 失效具有芳族酰胺单元和由其制备的纤维的可熔融加工的共聚酰胺
公开(公告)号：US4385170A
公开(公告)日：1983-05-24
申请号：US268516
申请日：1981-05-29
申请人： Matsuo Hirami , Kazushige Kudo , Tsutomu Sugie , Toshihide Hibino , Ryoichi Tsurutani , Shigemitsu Murase
发明人： Matsuo Hirami , Kazushige Kudo , Tsutomu Sugie , Toshihide Hibino , Ryoichi Tsurutani , Shigemitsu Murase
CPC分类号： C08G69/32 , C08G69/265
摘要： A melt-processable copolyamide prepared from diamines and dicarboxylic acids by a melt-polymerization process, wherein said copolyamide contains from about 1 to 20 mol % of an aromatic amide unit having the formula ##STR1## wherein X and Y are aromatic units with extended bonds, such as 1,4-phenylene group. This copolyamide provides fiber with higher stiffness.
摘要翻译： 一种通过熔融聚合方法由二胺和二羧酸制备的可熔融加工的共聚酰胺，其中所述共聚酰胺含有约1至20摩尔％的具有下式的芳族酰胺单元：其中X和Y是具有延伸键的芳族单元 ，如1,4-亚苯基。 该共聚酰胺提供具有较高刚度的纤维。
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7.发明授权Method for manufacturing heat-stable polyesters using phosphonic acid compounds with cyclic carbonates and catalyst 失效使用具有环状碳酸酯和催化剂的膦酸化合物制造热稳定性聚酯的方法
公开(公告)号：US4374961A
公开(公告)日：1983-02-22
申请号：US268312
申请日：1981-05-29
CPC分类号： C08G63/916
摘要： This invention is a method of manufacturing heat-stable polyesters, characterized in that phosphonic acid compounds are added, when heat-stable polyesters with decreased terminal carboxyl groups are manufactured by reacting polyesters and cyclic carbonate compounds in the presence of an alkali halide compound catalyst.
摘要翻译： 本发明是一种制备热稳定性聚酯的方法，其特征在于当碱金属卤化物化合物催化剂存在下，使聚酯和环状碳酸酯化合物反应制备具有降低的末端羧基的热稳定性聚酯时，加入膦酸化合物。
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