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公开(公告)号：US20180318248A1
公开(公告)日：2018-11-08
申请号：US15578704
申请日：2016-06-02
发明人： Yasunori YONEJIMA , Jun OGAWA , Shigenobu KISHINO
IPC分类号： A61K31/231 , A61K8/36 , A23L33/12
CPC分类号： A61K31/231 , A23D9/007 , A23K20/158 , A23L33/12 , A61K8/361 , A61K8/37 , A61P3/04 , A61P3/06 , A61P3/10 , A61Q1/00 , A61Q19/00 , C07C69/732
摘要： The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to an alkyl ester of 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, or ester of 10-hydroxy-cis-12-octadecenoic acid with dihydric alkanol or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.
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2.发明申请METHOD FOR PRODUCING RARE FATTY ACID USING NOVEL ENZYME, AND NOVEL RARE FATTY ACID 审中-公开使用新鲜食物生产稀有脂肪酸的方法和新鲜的稀释脂肪酸公开(公告)号：US20170022526A1
公开(公告)日：2017-01-26
申请号：US15113604
申请日：2015-01-23
发明人： Jun OGAWA , Shigenobu KISHINO , Teruo KAWADA , Nobuyuki TAKAHASHI , Tsuyoshi GOTO , Yasunori YONEJIMA
摘要： The present invention provides production of hydroxylated fatty acid by a hydration reaction using a novel enzyme derived from lactobacillus and using fatty acid as a substrate, and further, a production method of oxo fatty acid by an enzyme reaction or chemical oxidation reaction using the hydroxylated fatty acid as a substrate. In addition, a valuable novel rare fatty acid obtained by such production method is also provided.
摘要翻译： 本发明通过使用来自乳酸杆菌的新型酶和使用脂肪酸作为底物的水解反应来生产羟基化脂肪酸，此外，通过使用羟基化脂肪的酶反应或化学氧化反应的氧代脂肪酸的制造方法 酸作为底物。 此外，还提供了通过这种制备方法获得的有价值的新颖的稀有脂肪酸。
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公开(公告)号：US20150342916A1
公开(公告)日：2015-12-03
申请号：US14439146
申请日：2013-10-14
发明人： Jun OGAWA , Shigenobu KISHINO , Si-Bum PARK , Teruo KAWADA , Nobuyuki TAKAHASHI , Tsuyoshi GOTO , Hidekazu KIM , Tatsuya SUGAWARA , Takashi HIRATA , Yasunori YONEJIMA
IPC分类号： A61K31/201 , A61K31/20
CPC分类号： A61K31/202 , A23K20/158 , A23L33/12 , A61K31/20 , A61K31/201
摘要： The present invention provides a metabolism improving agent comprising an oxo fatty acid having 18 carbon atoms and a carbonyl group at the 10- or 12-position, and/or a hydroxy fatty acid having 18 carbon atoms and a hydroxyl group at the 10- and/or 12-position(s), and use of the metabolism improving agent as a food, a pharmaceutical product and the like.
摘要翻译： 本发明提供一种代谢改善剂，其包含具有18个碳原子的羰基和10或12位羰基的氧代脂肪酸和/或具有18个碳原子的羟基脂肪酸和在10位上的羟基 /或12位，以及使用代谢改善剂作为食品，药物等。
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公开(公告)号：US20190256876A1
公开(公告)日：2019-08-22
申请号：US16404241
申请日：2019-05-06
发明人： Jun OGAWA , Shigenobu KISHINO , Teruo KAWADA , Nobuyuki TAKAHASHI , Tsuyoshi GOTO , Yasunori YONEJIMA
摘要： The present invention provides production of hydroxylated fatty acid by a hydration reaction using a novel enzyme derived from lactobacillus and using fatty acid as a substrate, and further, a production method of oxo fatty acid by an enzyme reaction or chemical oxidation reaction using the hydroxylated fatty acid as a substrate. In addition, a valuable novel rare fatty acid obtained by such production method is also provided.
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公开(公告)号：US20170000752A1
公开(公告)日：2017-01-05
申请号：US15113714
申请日：2015-01-23
发明人： Jun OGAWA , Shigenobu KISHINO , Teruo KAWADA , Nobuyuki TAKAHASHI , Tsuyoshi GOTO , Tatsuya SUGAWARA , Yasunori YONEJIMA
IPC分类号： A61K31/20 , A61K31/202 , A61K31/201
CPC分类号： A61K31/20 , A23L33/12 , A61K31/201 , A61K31/202 , A61K45/06 , A61K2300/00
摘要： The present invention provides an anti-inflammatory agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the anti-inflammatory agent.
摘要翻译： 本发明提供含有稀有脂肪酸如羟基化脂肪酸，氧代脂肪酸等的抗炎剂，还含有含有抗炎剂的食品，药物等。
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公开(公告)号：US20210069141A1
公开(公告)日：2021-03-11
申请号：US16953129
申请日：2020-11-19
发明人： Jun OGAWA , Shigenobu KISHINO , Teruo KAWADA , Nobuyuki TAKAHASHI , Tsuyoshi GOTO , Tatsuya SUGAWARA , Yasunori YONEJIMA
IPC分类号： A61K31/20 , A61K31/201 , A61K31/202 , A61K45/06 , A23L33/12
摘要： The present invention provides an anti-inflammatory agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the anti-inflammatory agent.
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公开(公告)号：US20190218579A1
公开(公告)日：2019-07-18
申请号：US16369271
申请日：2019-03-29
CPC分类号： C12P7/6409 , C12P7/64 , C12P7/6427 , C12R1/25
摘要： The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.
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公开(公告)号：US20170007564A1
公开(公告)日：2017-01-12
申请号：US15113654
申请日：2015-01-23
发明人： Jun OGAWA , Shigenobu KISHINO , Teruo KAWADA , Nobuyuki TAKAHASHI , Tsuyoshi GOTO , Yasunori YONEJIMA
IPC分类号： A61K31/202 , A61K31/201
CPC分类号： A61K31/202 , A23L33/12 , A61K31/20 , A61K31/201 , A61K2300/00
摘要： The present invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.
摘要翻译： 本发明提供含有羟基化脂肪酸，氧代脂肪酸等稀有脂肪酸的代谢改善剂，还含有含有代谢改善剂的食品，药物等。
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公开(公告)号：US20180170854A1
公开(公告)日：2018-06-21
申请号：US15578694
申请日：2016-06-02
发明人： Yasunori YONEJIMA , Jun OGAWA , Shigenobu KISHINO
IPC分类号： C07C69/732 , A23K20/158 , A23L33/12 , A61K8/37
CPC分类号： C07C69/732 , A23D9/007 , A23K20/158 , A23L33/12 , A61K8/37 , A61K31/231 , A61Q1/00 , A61Q19/00 , C07B53/00 , C11C3/00
摘要： The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to a triglyceride in which at least one fatty acid forming an ester bond with a hydroxy group of glycerol is 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.
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公开(公告)号：US20170335355A1
公开(公告)日：2017-11-23
申请号：US15629716
申请日：2017-06-21
CPC分类号： C12P7/6409 , C12P7/64 , C12P7/6427 , C12R1/25
摘要： The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.
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