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公开(公告)号：US20070141620A1
公开(公告)日：2007-06-21
申请号：US11674476
申请日：2007-02-13
IPC分类号： C12Q1/68
CPC分类号： A61K47/60 , Y10S514/825 , Y10S514/903
摘要： PEG-IFN-β conjugates, where a PEG moiety is covalently bound to Cys17 of human IFN-β, are produced by a process of site specific PEGylation with a thiol reactive PEGylating agent. A pharmaceutical composition and a method for treating infections, tumors and autoimmune and inflammatory diseases are also provided. The invention further relates to a method for the stepwise attachment of PEG moieties in series to a polypeptide, and more particularly to IFN-β.
摘要翻译： 其中PEG部分共价结合人IFN-β的Cys 17的PEG-IFN-β缀合物通过用硫醇反应性聚乙二醇化剂进行位点特异性PEG化的方法产生。 还提供了用于治疗感染，肿瘤和自身免疫性和炎性疾病的药物组合物和方法。 本发明还涉及将PEG部分逐步连接到多肽，更具体地说涉及IFN-β的方法。
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公开(公告)号：US09155809B2
公开(公告)日：2015-10-13
申请号：US13249633
申请日：2011-09-30
IPC分类号： A61L2/18
CPC分类号： A61L2/18 , A61L2202/121 , A61L2202/122
摘要： A pen sterilization device includes a main body having a first end, a second end and a plurality of opposing sides defining a watertight reservoir for containing a sterilization agent. A pair of watertight valves are positioned along each end of the main body and function to allow ingress and egress of a pen to be cleaned. A central partition may be provided within the watertight reservoir having one or more brushes that are suspended in the sterilization agent for scrubbing a pen that is passing through the device.
摘要翻译： 笔式灭菌装置包括具有第一端，第二端和限定用于容纳灭菌剂的防水容器的多个相对侧的主体。 一对防水阀门沿着主体的每个端部定位，并且具有允许笔的进入和流出被清洁的功能。 可以在水密储存器内设置一个中央隔板，其中一个或多个刷子悬挂在消毒剂中，用于擦洗正在穿过该装置的笔。
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公开(公告)号：US20050032967A1
公开(公告)日：2005-02-10
申请号：US10888214
申请日：2004-07-09
申请人： Michael Roberts , Michael Roberts
发明人： Michael Roberts , Michael Roberts
IPC分类号： B32B25/04 , C08K3/00 , C09D5/00 , C09D5/02 , C09D201/00 , E02D31/06 , E04B1/66 , E04F13/02 , E04F21/00
CPC分类号： C09D5/02 , C09D201/00 , Y10T428/31826 , C08L2666/04
摘要： A wall comprising a first surface, and a protective coating covering at least a portion of the first surface, where the coating is the dried film of an aqueous composition comprising a first set of polymer particles characterized by having a glass transition temperature that is less than about −40° C., and a second set of polymer particles characterized by having a glass transition temperature in excess of about −25° C.
摘要翻译： 包括第一表面和覆盖第一表面的至少一部分的保护涂层的壁，其中涂层是包含第一组聚合物颗粒的水性组合物的干燥膜，其特征在于玻璃化转变温度小于 约-40℃，以及第二组聚合物颗粒，其特征在于玻璃化转变温度超过约-25℃。
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公开(公告)号：US09968992B2
公开(公告)日：2018-05-15
申请号：US14686906
申请日：2015-04-15
申请人： Michael Roberts
发明人： Michael Roberts
摘要： The present invention is a multipart system and method for using cloth filters in automated vertical molding. The system includes a filter setter, a filter print plate and a filter back shelf. The filter setter removably mounts to a mechanical arm and releasably carries at least one cloth filter between upper and lower jaws. The filter print plate mounts to a ram plate while the filter back shelf mounts to a swing plate. During vertical molding, the ram plate and swing plate compress sand to create a mold. The mounted filter print plate creates at least part of a print aperture into which the filter setter inserts the cloth filter. The apertures created by the filter print plate and the filter back shelf support the cloth filter during the founding process.
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公开(公告)号：US20180131788A1
公开(公告)日：2018-05-10
申请号：US15435188
申请日：2017-02-16
申请人： Michael Roberts
发明人： Michael Roberts
IPC分类号： H04L29/06 , G06F3/0481 , H04L29/08
CPC分类号： H04L67/38 , G06F3/04815 , H04L67/1095
摘要： One embodiment provides a system that facilitates shared virtual reality space. During operation, the system receives a first message associated with a first virtual reality object, wherein the first message includes a first address for the first virtual reality object and indicates a first action to be performed on the first virtual reality object. The system performs the first action on the first virtual reality object. The system determines a second address for a second virtual reality object that is remotely maintained and corresponds to the first virtual reality object. The system constructs a second message, which includes the second address and indicates the first action, thereby allowing the first action to be performed on the second virtual reality object.
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公开(公告)号：US08943419B2
公开(公告)日：2015-01-27
申请号：US12417932
申请日：2009-04-03
摘要： Embodiments of a system, a method, and a computer-program product (e.g., software) for collaboratively generating content from multiple users is described. This system may allow multiple users to create and maintain content that includes a complicated object, including linked spatial and text information, which can include dynamic spatial relationships between components in the complicated object. In particular, the system may receive one or more modifications to content associated with the complicated object from one or more users, and may provide signals to display the modified complicated object in a 3-d space or virtual environment on a display based at least in part on the cumulative modifications.
摘要翻译： 描述了用于从多个用户协同生成内容的系统，方法和计算机程序产品（例如，软件）的实施例。 该系统可以允许多个用户创建和维护包括复杂对象的内容，包括链接的空间和文本信息，其可以包括复杂对象中的组件之间的动态空间关系。 特别地，系统可以从一个或多个用户接收与复杂对象相关联的内容的一个或多个修改，并且可以提供信号以在显示器上的3-d空间或虚拟环境中显示经修改的复杂对象，至少基于 部分累积修改。
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公开(公告)号：US08879419B2
公开(公告)日：2014-11-04
申请号：US12510616
申请日：2009-07-28
申请人： Michael Roberts , Shekhar Gupta
发明人： Michael Roberts , Shekhar Gupta
CPC分类号： H04M1/2535 , H04L29/06027 , H04L65/1063 , H04L65/1069 , H04L65/1073 , H04L65/80
摘要： A system and method for establishing connection of an IP telephone to a network may include, in response to receiving a registration request from an IP telephone, generating a command to cause network access devices to ping the IP telephone. The command may be communicated to the network access devices. Ping information may be received in response to the network access devices pinging the IP telephone. A network access device may be selected that has the highest quality network access path to the IP telephone. In response to selecting the network access device that has the highest quality network access path, a network address of the selected network access device may be communicated to a network device to enable the IP telephone to communicate with the selected network access device. Credentials may be communicated to the IP telephone to register with the selected network access device.
摘要翻译： 用于建立IP电话到网络的连接的系统和方法可以包括响应于从IP电话接收到注册请求而产生使网络接入设备ping IP电话的命令。 该命令可以被传送到网络接入设备。 可以响应于ping IP电话的网络接入设备接收Ping信息。 可以选择具有到IP电话的最高质量的网络访问路径的网络接入设备。 响应于选择具有最高质量网络访问路径的网络接入设备，所选择的网络接入设备的网络地址可以被传送到网络设备，以使IP电话与所选择的网络接入设备进行通信。 凭证可以被传送到IP电话以向所选网络访问设备注册。
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公开(公告)号：US08851524B2
公开(公告)日：2014-10-07
申请号：US12447408
申请日：2006-11-10
IPC分类号： F16L37/096 , B60T17/04 , F16L37/092
CPC分类号： F16L37/0925 , B60T17/043 , F16L2201/10 , F16L2201/80 , Y10T29/49826
摘要： A positive completion coupler insert (100) configured to be inserted into a coupler (150) is provided according to the invention. The coupler insert (100) includes a conduit support insert (110) configured to be retained in a coupler bore (151) of the coupler (150) and a conduit support (140) configured to fit into and be retained by the conduit support insert (110). The conduit support (140) is configured to generate a first audible sound when inserted to a first insertion point in the conduit support insert (110) and is configured to generate a second audible sound when inserted to a second insertion point.
摘要翻译： 根据本发明，提供了构造成插入耦合器（150）中的正完成耦合器插入件（100）。 联接器插入件（100）包括构造成保持在联接器（150）的联接孔（151）中的导管支撑插入件（110）和导管支撑件（140），导管支撑件（140）被配置成装配到导管支撑插入件 （110）。 导管支撑件（140）被配置为当插入到导管支撑插入件（110）中的第一插入点时产生第一可听见的声音，并且被配置为当插入到第二插入点时产生第二可听见的声音。
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公开(公告)号：US20130325970A1
公开(公告)日：2013-12-05
申请号：US13484172
申请日：2012-05-30
申请人： Michael Roberts , Shane P. Ahern , Doron Kletter , Anselm Hook
发明人： Michael Roberts , Shane P. Ahern , Doron Kletter , Anselm Hook
IPC分类号： G06F15/16
CPC分类号： H04N21/4788 , H04N21/81 , H04N21/854
摘要： One embodiment of the present invention provides a system for sharing annotated videos. During operation, the system establishes a real-time video-sharing session between a remote field computer and a local computer. During the established real-time video-sharing session, the system receives a real-time video stream from a remote field computer, forwards the real-time video stream to a local computer to allow an expert to provide an annotation to the real-time video stream, receives the annotation from the local computer, and forwards the annotation to the remote field computer, which associates the annotation with a corresponding portion of the real-time video stream and displays the annotation on top of the corresponding portion of the real-time video stream.
摘要翻译： 本发明的一个实施例提供了一种用于共享带注释的视频的系统。 在操作期间，系统在远程现场计算机和本地计算机之间建立实时的视频共享会话。 在建立的实时视频共享会话期间，系统从远程现场计算机接收实时视频流，将实时视频流转发到本地计算机，以允许专家提供实时的注释 视频流，从本地计算机接收注释，并将注释转发到远程现场计算机，其将注释与实时视频流的对应部分相关联，并将该注释显示在实时视频流的对应部分之上， 时间视频流。
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公开(公告)号：US08531714B2
公开(公告)日：2013-09-10
申请号：US13229651
申请日：2011-09-09
申请人： Michael Roberts , Simon Banfield
发明人： Michael Roberts , Simon Banfield
CPC分类号： G06F19/3456 , G06F3/1243 , G06F19/00 , G06K15/02 , G06K15/024 , G06K15/028 , G06K15/1806 , G06K15/1807 , G06K15/1819 , G06K15/1868 , G06Q10/00 , G06Q50/22
摘要： A computer network system and method is provided for printing accompanying information and prescription labels in pharmacies. The system includes a central computer system; a pharmacy management system; and a data transmission network through which the pharmacy management system and the central computer system can communicate. The pharmacy management system may include an I/O terminal, a scanner, and a first printer. The pharmacy management system may receive and store prescription information for a prescription, and associate a prescription identification with the corresponding prescription. The pharmacy management system may print a prescription label for the prescription and an accompanying information print file.
摘要翻译： 提供计算机网络系统和方法，用于在药店中打印附带的信息和处方标签。 该系统包括一个中央计算机系统; 药房管理系统; 以及药房管理系统和中央计算机系统可以通过该数据传输网络进行通信。 药房管理系统可以包括I / O终端，扫描仪和第一打印机。 药房管理系统可以收到处方的处方信息，并将处方标识与相应的处方相关联。 药房管理系统可以打印处方的处方标签和附带的信息打印文件。
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