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1.发明授权公开(公告)号：US11673925B2
公开(公告)日：2023-06-13
申请号：US17811302
申请日：2022-07-07
发明人： Fang Wang , Xinchun Shen , Yong Fang , Zebin Weng
CPC分类号： C07K14/415 , A23L33/18 , A23L33/40 , A61K8/645 , A61P29/00 , A61Q19/00 , A23V2002/00 , A61K38/00
摘要： An oligopeptide with anti-inflammatory activity, a preparation method, and an application thereof are provided, belonging to the field of biotechnology. An amino acid sequence of the oligopeptide is shown as SEQ ID NO:1. The preparation method includes: digesting a wheat germ protein through a simulated gastrointestinal tract to obtain protein digestion products; separating the protein digestion products by ultrafiltration membranes to obtain components I (>3 kDa), II (1˜3 kDa), and III (
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公开(公告)号：US20240084357A1
公开(公告)日：2024-03-14
申请号：US18461604
申请日：2023-09-06
发明人： Fang Wang , Xinchun Shen , Yong Fang , Zebin Weng
摘要： An oligopeptide with lipid-lowering activity, a preparation method and an application thereof are provided, belonging to the field of biotechnology. The amino acid sequence of the oligopeptide with lipid-lowering activity is shown in SEQ ID NO: 1. The preparation method includes the following steps: (1) hydrolyzing a loach protein with proteases to obtain an enzymatic hydrolysis product; (2) separating the enzymatic hydrolysis product using an ultrafiltration membrane, and taking a component with a molecular weight less than 3 kilodalton (kDa); and (3) filtering and separating the component with the molecular weight less than 3 kDa by Sephadex G-15 to obtain the oligopeptide. The oligopeptide is derived from the loach protein and has the characteristics of high safety, high efficiency, and wide sources.
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公开(公告)号：US12077797B2
公开(公告)日：2024-09-03
申请号：US18461604
申请日：2023-09-06
发明人： Fang Wang , Xinchun Shen , Yong Fang , Zebin Weng
摘要： An oligopeptide with lipid-lowering activity, a preparation method and an application thereof are provided, belonging to the field of biotechnology. The amino acid sequence of the oligopeptide with lipid-lowering activity is shown in SEQ ID NO: 1. The preparation method includes the following steps: (1) hydrolyzing a loach protein with proteases to obtain an enzymatic hydrolysis product; (2) separating the enzymatic hydrolysis product using an ultrafiltration membrane, and taking a component with a molecular weight less than 3 kilodalton (kDa); and (3) filtering and separating the component with the molecular weight less than 3 kDa by Sephadex G-15 to obtain the oligopeptide. The oligopeptide is derived from the loach protein and has the characteristics of high safety, high efficiency, and wide sources.
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4.发明申请公开(公告)号：US20230008335A1
公开(公告)日：2023-01-12
申请号：US17811302
申请日：2022-07-07
发明人： FANG WANG , Xinchun Shen , Yong Fang , Zebin Weng
摘要： An oligopeptide with anti-inflammatory activity, a preparation method, and an application thereof are provided, belonging to the field of biotechnology. An amino acid sequence of the oligopeptide is shown as SEQ ID NO:1. The preparation method includes: digesting a wheat germ protein through a simulated gastrointestinal tract to obtain protein digestion products; separating the protein digestion products by ultrafiltration membranes to obtain components I (>3 kDa), II (1˜3 kDa), and III (
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