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1.发明申请公开(公告)号：US20230008335A1
公开(公告)日：2023-01-12
申请号：US17811302
申请日：2022-07-07
发明人： FANG WANG , Xinchun Shen , Yong Fang , Zebin Weng
摘要： An oligopeptide with anti-inflammatory activity, a preparation method, and an application thereof are provided, belonging to the field of biotechnology. An amino acid sequence of the oligopeptide is shown as SEQ ID NO:1. The preparation method includes: digesting a wheat germ protein through a simulated gastrointestinal tract to obtain protein digestion products; separating the protein digestion products by ultrafiltration membranes to obtain components I (>3 kDa), II (1˜3 kDa), and III (
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2.发明授权公开(公告)号：US11673925B2
公开(公告)日：2023-06-13
申请号：US17811302
申请日：2022-07-07
发明人： Fang Wang , Xinchun Shen , Yong Fang , Zebin Weng
CPC分类号： C07K14/415 , A23L33/18 , A23L33/40 , A61K8/645 , A61P29/00 , A61Q19/00 , A23V2002/00 , A61K38/00
摘要： An oligopeptide with anti-inflammatory activity, a preparation method, and an application thereof are provided, belonging to the field of biotechnology. An amino acid sequence of the oligopeptide is shown as SEQ ID NO:1. The preparation method includes: digesting a wheat germ protein through a simulated gastrointestinal tract to obtain protein digestion products; separating the protein digestion products by ultrafiltration membranes to obtain components I (>3 kDa), II (1˜3 kDa), and III (
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公开(公告)号：US11453730B2
公开(公告)日：2022-09-27
申请号：US17429637
申请日：2020-08-05
发明人： Chao Ding , Huajuan Zhang , Tingting Tao
摘要： The method employs citric acid as the modifier, combines the citric acid with starch, achieves the good modification effect of starch at high temperature, and improves the digestion-resistant property of starch. Citric acid itself is nontoxic, the process conditions are mild and the treatment methods are relatively safe, which shows very high practical values. In the method, starch and citric acid are cross-linked by using the infrared treatment technology, and the dry heating treatment is used to promote the modifier citric acid into starch, thereby achieving significant and stable modification effects, and high modification efficiency.
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公开(公告)号：US20240084357A1
公开(公告)日：2024-03-14
申请号：US18461604
申请日：2023-09-06
发明人： Fang Wang , Xinchun Shen , Yong Fang , Zebin Weng
摘要： An oligopeptide with lipid-lowering activity, a preparation method and an application thereof are provided, belonging to the field of biotechnology. The amino acid sequence of the oligopeptide with lipid-lowering activity is shown in SEQ ID NO: 1. The preparation method includes the following steps: (1) hydrolyzing a loach protein with proteases to obtain an enzymatic hydrolysis product; (2) separating the enzymatic hydrolysis product using an ultrafiltration membrane, and taking a component with a molecular weight less than 3 kilodalton (kDa); and (3) filtering and separating the component with the molecular weight less than 3 kDa by Sephadex G-15 to obtain the oligopeptide. The oligopeptide is derived from the loach protein and has the characteristics of high safety, high efficiency, and wide sources.
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公开(公告)号：US12077797B2
公开(公告)日：2024-09-03
申请号：US18461604
申请日：2023-09-06
发明人： Fang Wang , Xinchun Shen , Yong Fang , Zebin Weng
摘要： An oligopeptide with lipid-lowering activity, a preparation method and an application thereof are provided, belonging to the field of biotechnology. The amino acid sequence of the oligopeptide with lipid-lowering activity is shown in SEQ ID NO: 1. The preparation method includes the following steps: (1) hydrolyzing a loach protein with proteases to obtain an enzymatic hydrolysis product; (2) separating the enzymatic hydrolysis product using an ultrafiltration membrane, and taking a component with a molecular weight less than 3 kilodalton (kDa); and (3) filtering and separating the component with the molecular weight less than 3 kDa by Sephadex G-15 to obtain the oligopeptide. The oligopeptide is derived from the loach protein and has the characteristics of high safety, high efficiency, and wide sources.
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