公开(公告)号：US07661820B2

公开(公告)日：2010-02-16

申请号：US11883288

申请日：2006-01-18

申请人： Naoko Hara ,  Hisashi Kataoka ,  Chihiro Kato

发明人： Naoko Hara ,  Hisashi Kataoka ,  Chihiro Kato

IPC分类号： A61B3/14 ,  A61B3/10 ,  A61B3/00

CPC分类号： A61B3/101

摘要： The present invention provides an ophthalmologic apparatus that can noninvasively measure the state of the lacrimal layer formed on the cornea surface and that can quantitatively measure the state of the lacrimal layer without utilizing a reflection image from the retina.The ophthalmologic apparatus according to the present invention comprises an optical projection system for projecting light of a specified pattern onto a cornea surface, and an imaging device for photographing a reflection image of the projected light from the cornea surface. An operating unit calculates the degree of distortion of the reflection image on the basis of the density value distribution of the image photographed by the imaging device. The operating unit can determine the state of the lacrimal layer using the calculated degree of distortion.

摘要翻译： 本发明提供一种眼科装置，其可以非侵入性地测量形成在角膜表面上的泪液层的状态，并且可以定量地测量泪液层的状态，而不利用来自视网膜的反射图像。 根据本发明的眼科装置包括用于将指定图案的光投射到角膜表面上的光学投影系统和用于拍摄来自角膜表面的投射光的反射图像的成像装置。 操作单元基于由成像装置拍摄的图像的浓度值分布来计算反射图像的失真度。 操作单元可以使用计算的失真程度确定泪液层的状态。

公开(公告)号：US20080309872A1

公开(公告)日：2008-12-18

申请号：US11883288

申请日：2006-01-18

申请人： Naoko Hara ,  Hisashi Kataoka ,  Chihiro Kato

发明人： Naoko Hara ,  Hisashi Kataoka ,  Chihiro Kato

IPC分类号： A61B3/14

CPC分类号： A61B3/101

摘要： The present invention provides an opthalmologic apparatus that can noninvasively measure the state of the lacrimal layer formed on the cornea surface and that can quantitatively measure the state of the lacrimal layer without utilizing a reflection image from the retina.The opthalmologic apparatus according to the present invention comprises an optical projection system for projecting light of a specified pattern onto a cornea surface, and an imaging device for photographing a reflection image of the projected light from the cornea surface. An operating unit calculates the degree of distortion of the reflection image on the basis of the density value distribution of the image photographed by the imaging device. The operating unit can determine the state of the lacrimal layer using the calculated degree of distortion.

摘要翻译： 本发明提供了一种可以非侵入性地测量在角膜表面上形成的泪液层的状态并且可以定量测量泪液层的状态而不利用来自视网膜的反射图像的眼科装置。 根据本发明的眼科装置包括用于将指定图案的光投射到角膜表面上的光学投影系统和用于拍摄来自角膜表面的投影光的反射图像的成像装置。 操作单元基于由成像装置拍摄的图像的浓度值分布来计算反射图像的失真度。 操作单元可以使用计算的失真程度确定泪液层的状态。

公开(公告)号：US08758625B2

公开(公告)日：2014-06-24

申请号：US13120753

申请日：2009-09-25

申请人： Chihiro Kato ,  Yuukou Seki ,  Satoshi Shiki

发明人： Chihiro Kato ,  Yuukou Seki ,  Satoshi Shiki

IPC分类号： B01D61/00 ,  B01D69/08 ,  B01D71/68 ,  B01D71/26 ,  B01D39/00

CPC分类号： B01D61/00 ,  B01D61/147 ,  B01D65/02 ,  B01D69/087 ,  B01D71/44 ,  B01D71/68 ,  B01D2311/165 ,  B01D2315/18 ,  B01D2321/04 ,  B01D2321/18 ,  B01D2323/12

摘要： Use of a porous hollow fiber membrane for producing a clarified biomedical culture medium by a method including a filtration step of distributing a biomedical culture medium over the porous hollow fiber membrane, a tube wall of the hollow fiber membrane being constituted of a blend of a hydrophobic polymer and polyvinylpyrrolidone. A content of the polyvinylpyrrolidone is not lower than 0.2% by mass and not higher than 3% by mass relative to a total mass of the porous hollow fiber membrane, and, when the tube wall is divided in a membrane-thickness direction equally into three regions, a content of the polyvinylpyrrolidone in an outer circumferential region including an outer face is higher than a content of the polyvinylpyrrolidone in an inner circumferential region including an inner face, and an average pore size in the inner face is larger than an average pore size in the outer face.

摘要翻译： 使用多孔中空纤维膜通过包括在多孔中空纤维膜上分配生物医学培养基的过滤步骤的方法生产澄清的生物医学培养基，中空纤维膜的管壁由疏水性 聚合物和聚乙烯吡咯烷酮。 聚乙烯吡咯烷酮的含量相对于多孔中空纤维膜的总质量为0.2质量％以上且3质量％以下，并且当将管壁以膜厚度方向等分成三份 区域中，包含外表面的外周区域中的聚乙烯吡咯烷酮的含量比包含内表面的内周区域中的聚乙烯吡咯烷酮的含量高，并且内表面的平均孔径大于平均孔径 在外面。

公开(公告)号：US4265826A

公开(公告)日：1981-05-05

申请号：US106011

申请日：1979-12-21

申请人： Masaaki Iida ,  Chihiro Kato ,  Shigemitsu Ohshima ,  Yoshiyuki Yazawa

发明人： Masaaki Iida ,  Chihiro Kato ,  Shigemitsu Ohshima ,  Yoshiyuki Yazawa

IPC分类号： C11B7/00 ,  C09F5/10 ,  C11B3/00

CPC分类号： C11B7/0075

摘要： A method is provided for fractionating an oil to separate high melting components thereof, which comprises the steps of:(a) adjusting the temperature of an oil or fat to a temperature from the complete melting point to thirty Celsius degrees above the slip melting point of the oil or fat;(b) seeding the temperature-adjusted oil or fat with seed crystals of the high melting point components of said oil or fat;(c) cooling said seeded oil or fat below said temperature to crystallize said high melting point components; and(d) separating the crystals of said high melting point components from the slurry obtained in step (c).

摘要翻译： 提供了一种用于分馏油以分离其高熔点​​成分的方法，其包括以下步骤：（a）将油或脂肪的温度调节到从完全熔点到高于熔点的熔点至摄氏30摄氏度的温度 油或脂肪; （b）用温度调节的油或脂肪用所述油或脂肪的高熔点组分的晶种接种; （c）将所述接种的油或脂肪冷却至低于所述温度以使所述高熔点组分结晶; 和（d）从步骤（c）中获得的浆料中分离所述高熔点组分的晶体。

公开(公告)号：US08265735B2

公开(公告)日：2012-09-11

申请号：US12331752

申请日：2008-12-10

申请人： Chihiro Kato ,  Keiichiro Okamoto ,  Kenichi Hayashi ,  Hiromu Watanabe

发明人： Chihiro Kato ,  Keiichiro Okamoto ,  Kenichi Hayashi ,  Hiromu Watanabe

IPC分类号： A61B6/00

CPC分类号： A61B5/0066 ,  A61B5/117

摘要： An optical coherence tomography (OCT) anterior eye part imaging apparatus includes a tomographic image obtaining unit obtaining a tomographic image of an anterior eye part of subject's eye in a depth direction by optical coherence tomography, an imaging unit imaging a frontal image of subject's eye, a display unit displaying the image of subject's eye, a corneal apex location detecting unit detecting a location of subject's eye, an alignment unit moving an apparatus body relative to the holder so that the location of corneal apex corresponds with a predetermined image obtaining location, a designating unit designating an area or a location where the tomographic image is obtained on subject's frontal image displayed on the display unit, and a scan line setting unit setting a scan line in the tomographic image obtaining unit on a straight line passing the corneal apex according to the designated area or location.

摘要翻译： 光学相干断层摄影（OCT）前眼部成像装置包括：断层摄影图像获取单元，通过光学相干断层摄影获得被摄体眼睛的前眼部分的深度方向的断层图像;成像单元，对被检眼的正面图像进行成像; 显示被检者眼睛的图像的显示单元，检测被检眼的位置的角膜顶点位置检测单元，对准单元相对于保持器移动设备主体，使得角膜顶点的位置对应于预定图像获取位置， 指定单元，其指定在显示单元上显示的被摄体的正面图像上获得断层图像的区域或位置;以及扫描线设置单元，其在通过所述角膜顶点的直线上设置所述断层图像获取单元中的扫描线，根据 指定区域或位置。

公开(公告)号：US20120200827A1

公开(公告)日：2012-08-09

申请号：US13355974

申请日：2012-01-23

申请人： Chihiro Kato ,  Tsutomu Ohmori ,  Yuji Nozawa

发明人： Chihiro Kato ,  Tsutomu Ohmori ,  Yuji Nozawa

IPC分类号： A61B3/10

CPC分类号： A61B3/1173 ,  A61B3/1005 ,  A61B3/102 ,  A61B3/12 ,  G01B9/02004 ,  G01B9/02062 ,  G01B9/02064 ,  G01B9/02068 ,  G01B9/02091

摘要： An ophthalmologic apparatus comprises a light source 12, an optical measurement system 13 that radiates first light from the light source to inside an eye to be examined and guides first reflected light from the eye, an optical reference system (24, 22) that radiates second light from the light source to a reference surface and guides second reflected light from the reference surface, a photo detector 26 that detects interfering light between the first reflected light from the optical measurement system and the second reflected light from the optical reference system, and a processor that determines a position of a measuring portion of the inside of the eye based on the detected interfering light. The optical measurement system comprises an incident angle changing member 46 that changes an incident angle of the first light radiated to the eye within a predetermined angular range relative to an axis of vision of the eye.

摘要翻译： 一种眼科装置，包括光源12，光学测量系统13，其将来自光源的第一光辐射到待检查的眼睛内部并引导来自眼睛的第一反射光;光学参考系统（24,22），其辐射第二 从光源到参考表面的光并且引导来自参考表面的第二反射光;光电检测器26，其检测来自光学测量系统的第一反射光和来自光学参考系的第二反射光之间的干涉光;以及 处理器，其基于检测到的干涉光确定眼睛内部的测量部分的位置。 光学测量系统包括入射角度改变构件46，其将照射到眼睛的第一光的入射角相对于眼睛的视线改变在预定角度范围内。

公开(公告)号：US09119571B2

公开(公告)日：2015-09-01

申请号：US13355974

申请日：2012-01-23

申请人： Chihiro Kato ,  Tsutomu Ohmori ,  Yuji Nozawa

发明人： Chihiro Kato ,  Tsutomu Ohmori ,  Yuji Nozawa

IPC分类号： A61B3/12 ,  A61B3/117 ,  A61B3/10 ,  G01B9/02

CPC分类号： A61B3/1173 ,  A61B3/1005 ,  A61B3/102 ,  A61B3/12 ,  G01B9/02004 ,  G01B9/02062 ,  G01B9/02064 ,  G01B9/02068 ,  G01B9/02091

摘要： An ophthalmologic apparatus comprises a light source 12, an optical measurement system 13 that radiates first light from the light source to inside an eye to be examined and guides first reflected light from the eye, an optical reference system (24, 22) that radiates second light from the light source to a reference surface and guides second reflected light from the reference surface, a photo detector 26 that detects interfering light between the first reflected light from the optical measurement system and the second reflected light from the optical reference system, and a processor that determines a position of a measuring portion of the inside of the eye based on the detected interfering light. The optical measurement system comprises an incident angle changing member 46 that changes an incident angle of the first light radiated to the eye within a predetermined angular range relative to an axis of vision of the eye.

摘要翻译： 一种眼科装置，包括光源12，光学测量系统13，其将来自光源的第一光辐射到待检查的眼睛内部并引导来自眼睛的第一反射光;光学参考系统（24,22），其辐射第二 从光源到参考表面的光并且引导来自参考表面的第二反射光;光电检测器26，其检测来自光学测量系统的第一反射光和来自光学参考系的第二反射光之间的干涉光;以及 处理器，其基于检测到的干涉光确定眼睛内部的测量部分的位置。 光学测量系统包括入射角度改变构件46，其将照射到眼睛的第一光的入射角相对于眼睛的视线改变在预定角度范围内。

公开(公告)号：US20110210067A1

公开(公告)日：2011-09-01

申请号：US13120753

申请日：2009-09-25

申请人： Chihiro Kato ,  Yuukou Seki ,  Satoshi Shiki

发明人： Chihiro Kato ,  Yuukou Seki ,  Satoshi Shiki

IPC分类号： B01D11/04

CPC分类号： B01D61/00 ,  B01D61/147 ,  B01D65/02 ,  B01D69/087 ,  B01D71/44 ,  B01D71/68 ,  B01D2311/165 ,  B01D2315/18 ,  B01D2321/04 ,  B01D2321/18 ,  B01D2323/12

摘要： Use of a porous hollow fiber membrane for producing a clarified biomedical culture medium by a method including a filtration step of distributing a biomedical culture medium over the porous hollow fiber membrane, a tube wall of the hollow fiber membrane being constituted of a blend of a hydrophobic polymer and polyvinylpyrrolidone. A content of the polyvinylpyrrolidone is not lower than 0.2% by mass and not higher than 3% by mass relative to a total mass of the porous hollow fiber membrane, and, when the tube wall is divided in a membrane-thickness direction equally into three regions, a content of the polyvinylpyrrolidone in an outer circumferential region including an outer face is higher than a content of the polyvinylpyrrolidone in an inner circumferential region including an inner face, and an average pore size in the inner face is larger than an average pore size in the outer face.

摘要翻译： 使用多孔中空纤维膜通过包括在多孔中空纤维膜上分配生物医学培养基的过滤步骤的方法生产澄清的生物医学培养基，中空纤维膜的管壁由疏水性 聚合物和聚乙烯吡咯烷酮。 聚乙烯吡咯烷酮的含量相对于多孔中空纤维膜的总质量为0.2质量％以上且3质量％以下，并且当将管壁以膜厚度方向等分成三份 区域中，包含外表面的外周区域中的聚乙烯吡咯烷酮的含量比包含内表面的内周区域中的聚乙烯吡咯烷酮的含量高，并且内表面的平均孔径大于平均孔径 在外面。

公开(公告)号：US4954406A

公开(公告)日：1990-09-04

申请号：US265557

申请日：1988-11-01

申请人： Keiichi Endo ,  Yasushi Shinbo ,  Akira Kageyama ,  Yasuo Katsuya ,  Chihiro Kato ,  Masato Fukasawa ,  Makoto Sekine

发明人： Keiichi Endo ,  Yasushi Shinbo ,  Akira Kageyama ,  Yasuo Katsuya ,  Chihiro Kato ,  Masato Fukasawa ,  Makoto Sekine

IPC分类号： G03G5/14

CPC分类号： G03G5/142

摘要： In an electrophotographic plate, that having an undercoating layer with smooth surface when observed by using a scanning electron microscope and an electric conductivity of at least 2.times.10.sup.-14 .OMEGA..sup.-1 .multidot.cm.sup.-1 between an electroconductive substrate and a photosensitive layer is improved in electrophotographic properties which are hardly changed by changes of circumstances.