公开(公告)号：US4891236A

公开(公告)日：1990-01-02

申请号：US256147

申请日：1988-10-07

申请人： Naotake Ohta ,  Masahiro Yotsumoto ,  Haruo Nishino ,  Hiroshi Tanahashi ,  Hajime Kato ,  Toshiaki Tazawa ,  Hideo Noda ,  Yuzuru Wakabayashi

发明人： Naotake Ohta ,  Masahiro Yotsumoto ,  Haruo Nishino ,  Hiroshi Tanahashi ,  Hajime Kato ,  Toshiaki Tazawa ,  Hideo Noda ,  Yuzuru Wakabayashi

IPC分类号： C12G1/00 ,  B01D9/00 ,  B01D9/02 ,  C12G1/12 ,  C12H1/02 ,  C12H1/08

CPC分类号： C12H1/08 ,  B01D9/0013

摘要： An externally cooled cylindrical vessel has a draft tube centered in the lower half thereof. A continuous circulation seeded with tartars crystals includes a fast downward flow through the draft tube and a slow upward flow outside the draft tube. The circulation induces crystal growth and the removal of tartars from the liquid. A coning zone is defined in the vessel above the draft tube. The slow upward flow moves toward the calming zone, facilitating classification of the crystalline matter which is reintroduced into the fact downward flow. The liquid product from which the tartars has been removed and which is collected in the upper section of the vessel is tapped off by an overflow port located near the top of the vessel.

公开(公告)号：US4798131A

公开(公告)日：1989-01-17

申请号：US909329

申请日：1986-09-19

申请人： Naotake Ohta ,  Masahiro Yotsumoto ,  Haruo Nishino ,  Hiroshi Tanahashi ,  Hajime Kato ,  Toshiaki Tazawa ,  Hideo Noda ,  Yuzuru Wakabayashi

发明人： Naotake Ohta ,  Masahiro Yotsumoto ,  Haruo Nishino ,  Hiroshi Tanahashi ,  Hajime Kato ,  Toshiaki Tazawa ,  Hideo Noda ,  Yuzuru Wakabayashi

IPC分类号： C12G1/00 ,  B01D9/00 ,  B01D9/02 ,  C12G1/12 ,  C12H1/02 ,  C12H1/08 ,  C12F1/00

CPC分类号： C12H1/08 ,  B01D9/0013

摘要： An externally cooled cylindrical vessel has a draft tube centered in the lower half thereof. A continuous circulation seeded with tartars crystals includes a fast downward flow through the draft tube and a slow upward flow outside the draft tube. The circulation induces crystal growth and the removal of tartars from the liquid. A coning zone is defined in the vessel above the draft tube. The slow upward flow moves toward the calming zone, facilitating classification of the crystalline matter which is reintroduced into the fact downward flow. The liquid product from which the tartars has been removed and which is collected in the upper section of the vessel is tapped off by an overflow port located near the top of the vessel.

摘要翻译： 外部冷却的圆柱形容器具有在其下半部中心的引流管。 用鞑靼晶体接种的连续循环包括通过引流管的快速向下流动和引流管外部的缓慢向上流动。 循环引起晶体生长并从液体中除去牙垢。 在引流管上方的容器中限定了锥形区域。 缓慢向上的流动朝向平静区域移动，便于结晶物质的分类，其被重新引入事实向下流动。 从容器顶部排出的溢流口，将从其中除去并被收集在容器上部的塔尔液体的液体产品分开。

公开(公告)号：US08859245B2

公开(公告)日：2014-10-14

申请号：US12294376

申请日：2007-03-08

申请人： Hiroshi Uyama ,  Hideo Noda ,  Takahiko Terada

发明人： Hiroshi Uyama ,  Hideo Noda ,  Takahiko Terada

IPC分类号： C12P7/62 ,  C12P7/00 ,  B01D11/04 ,  C07C51/48

CPC分类号： B01D11/0488 ,  B01D11/0492 ,  C07C51/48 ,  Y02P20/582 ,  C07C59/08

摘要： A lactic acid component (e.g., lactic acid or oligo (lactic acid)) can be obtained by extraction from a lactic acid fermentation liquor with a pH of 4.8 or less, using at least one solvent selected from the group consisting of toluene, xylene, mesitylene, ethylbenzene, methanol, ethanol, propanol, butanol, and mineral spirit. Furthermore, oligo (lactic acid) can be obtained, by heating a lactic acid fermentation liquor with a pH of 4.8 or less under reduced pressure, and washing, with water, the fermentation liquor containing a produced oligo (lactic acid). Hence, a method is provided for separating a lactic acid component from a lactic acid fermentation liquor, which is free from incorporation of impurities and which includes simple steps.

摘要翻译： 使用至少一种选自甲苯，二甲苯，二氯甲烷，二氯甲烷，二氯甲烷，二氯甲烷， 均三甲苯，乙苯，甲醇，乙醇，丙醇，丁醇和矿物精。 此外，通过在减压下加热pH4.8以下的乳酸发酵液，并用水洗涤含有生成的寡聚（乳酸）的发酵液，可以得到寡聚（乳酸）。 因此，提供了从不含杂质的乳酸发酵液中分离乳酸成分的方法，其包括简单的步骤。

公开(公告)号：US08557586B2

公开(公告)日：2013-10-15

申请号：US12964808

申请日：2010-12-10

申请人： Akihiko Kondo ,  Ryosuke Yamada ,  Hideo Noda

发明人： Akihiko Kondo ,  Ryosuke Yamada ,  Hideo Noda

IPC分类号： C12N1/22 ,  C12N15/81

CPC分类号： C12N1/22 ,  C12N15/815

摘要： The present invention provides a method for producing a cellulose degradable yeast, comprising the step of co-introducing genes coding for at least two cellulose-degrading enzymes into a yeast host via integration with a yeast δ sequence. According to the invention, a yeast having an improved cellulose degradation ability are provided.

摘要翻译： 本发明提供了一种生产纤维素可降解酵母的方法，其包括将编码至少两种纤维素降解酶的基因通过与酵母δ序列整合而共同引入酵母宿主的步骤。 根据本发明，提供了具有改善的纤维素降解能力的酵母。

公开(公告)号：US20110196136A1

公开(公告)日：2011-08-11

申请号：US13125040

申请日：2009-10-21

申请人： Masamitsu Funaoka ,  Keigo Mikame ,  Hideo Noda

发明人： Masamitsu Funaoka ,  Keigo Mikame ,  Hideo Noda

IPC分类号： B01J19/18 ,  C08H7/00

CPC分类号： C07G1/00 ,  C13K1/02

摘要： Provided is a Phase-Separation system plant for botanical resource, a conversion method, a concentrated acid treatment unit, and a concentrated acid treatment method by which lignin derivatives and hydrolyzed carbohydrate are manufactured out of a botanical resource efficiently and continuously. A concentrated acid treatment unit (3) is composed of a reaction section (20) and an agitation extraction section (25). A phenol sorped raw material (16) obtained by defatting botanical resource-derived raw material (15) by solvent (14) to subject sorption phenols (13) to sorption is introduced, thus obtaining mixed solution of phenol solution including a lignophenol derivative and concentrated acid solution including a cellulose hydrolysate. The reaction section (20) agitates and mixes the phenol sorped raw material (16) and concentrated acid (21A) to cause cellulose to be swollen to thereby convert lignin to lignophenol. A part of the cellulose is subjected to hydrolysis. The agitation extraction section (25) receives the treated liquid sent from the reaction section (20) and adds phenols for extraction (33) thereto to cause lignophenol dispersed in the concentrated acid solution to be dissolved and extracted in phenols for extraction.

摘要翻译： 提供了一种用于植物资源的相分离系统植物，转化方法，浓酸处理单元和浓缩酸处理方法，通过该浓缩酸处理方法，有效和连续地由植物资源制造木质素衍生物和水解碳水化合物。 浓酸处理装置（3）由反应部（20）和搅拌抽出部（25）构成。 引入通过用溶剂（14）将植物资源衍生的原料（15）脱脂以吸附苯酚（13）吸附而获得的苯酚吸收的原料（16），从而获得包含木酚酚衍生物和浓缩的 酸溶液，包括纤维素水解产物。 反应段（20）搅拌并混合苯酚吸收的原料（16）和浓酸（21A），导致纤维素溶胀，从而将木质素转化成木质素。 将一部分纤维素进行水解。 搅拌提取部（25）接收从反应部（20）送出的处理液，向其中添加酚类（33），使分散在浓酸溶液中的苯酚溶解并萃取到酚类中进行萃取。

公开(公告)号：US20100261235A1

公开(公告)日：2010-10-14

申请号：US12745962

申请日：2008-11-28

申请人： Nobuyuki Kuratani ,  Shinji Hama ,  Hideo Noda ,  Hideki Fukuda

发明人： Nobuyuki Kuratani ,  Shinji Hama ,  Hideo Noda ,  Hideki Fukuda

IPC分类号： C12P7/64 ,  C12M1/02

CPC分类号： C12P7/649 ,  C10G2300/1011 ,  C11C3/003 ,  C12P7/62 ,  Y02E50/13 ,  Y02P30/20

摘要： A method for continuously producing a fatty acid ester of the present invention comprises (a) mixing and agitating an oil and fat starting material and a lower alcohol, and supplying a mixture to one of the catalyst reaction tubes filled with a lipase; (b) producing a fatty acid ester and glycerin in the catalyst reaction tube; (c) introducing an outflowing liquid from the catalyst reaction tube into a glycerin separation tank, thereby collecting the glycerin; (d) adding a lower alcohol to a separated liquid obtained by separating the glycerin from the outflowing liquid, mixing and agitating an obtained material, and supplying a mixture to a following catalyst reaction tube; (e) repeating the steps (b) to (d) until supply to a last catalyst reaction tube is performed; and (f) collecting a fatty acid ester from the separated liquid obtained from the last catalyst reaction tube. According to the method of the present invention, the concentration of a lower alcohol can be strictly controlled and by product glycerin can be automatically removed.

摘要翻译： 本发明的连续生产脂肪酸酯的方法包括：（a）将油脂原料和低级醇混合搅拌，向填充有脂肪酶的催化剂反应管之一供给混合物; （b）在催化剂反应管中制备脂肪酸酯和甘油; （c）将来自催化剂反应管的流出液引入甘油分离槽中，从而收集甘油; （d）向从流出液中分离甘油得到的分离液中加入低级醇，混合搅拌所得物质，向后述催化剂反应管供给混合物; （e）重复步骤（b）至（d），直到进行最后一个催化剂反应管的供应; 和（f）从最后一个催化剂反应管获得的分离液中收集脂肪酸酯。 根据本发明的方法，可以严格控制低级醇的浓度，并且可以自动除去产物甘油。

公开(公告)号：US20090275110A1

公开(公告)日：2009-11-05

申请号：US12431102

申请日：2009-04-28

申请人： Akihiko Kondo ,  Hideki Fukuda ,  Tsutomu Tanaka ,  Hideo Noda

发明人： Akihiko Kondo ,  Hideki Fukuda ,  Tsutomu Tanaka ,  Hideo Noda

IPC分类号： C12N1/20 ,  C12N1/16

CPC分类号： C12N15/1037 ,  C12N9/93

摘要： Provided is a microorganism that can display, on the cell surface, any molecules other than a molecule comprising amino acids, more specifically, a microorganism that displays biotin on a cell surface. The microorganism is capable of co-expressing a biotinylating enzyme and an acceptor peptide having a sequence recognized by the biotinylating enzyme, wherein the acceptor peptide is expressed on the cell surface, so that lysine of the acceptor peptide is biotinylated to display biotin on the cell surface. Also provided is a method for displaying an intended molecule, including not only a molecule comprising amino acids but also any molecules, on a cell surface of a microorganism.

摘要翻译： 本发明提供能够在细胞表面上显示除氨基酸分子以外的任何分子，更具体地，在细胞表面上显示生物素的微生物的微生物。 微生物能够共表达生物素化酶和具有由生物素化酶识别的序列的受体肽，其中受体肽在细胞表面上表达，使得受体肽的赖氨酸被生物素化以在细胞上显示生物素 表面。 还提供了在微生物的细胞表面上显示预期分子的方法，不仅包括包含氨基酸的分子，而且包括任何分子。

公开(公告)号：US06595612B1

公开(公告)日：2003-07-22

申请号：US09510484

申请日：2000-02-23

申请人： Christopher M. Brown ,  Hideo Noda ,  Toru Hayashi

发明人： Christopher M. Brown ,  Hideo Noda ,  Toru Hayashi

IPC分类号： B41J2938

CPC分类号： B41J2/2132 ,  B41J19/147

摘要： An inkjet printer capable of minimizing chromatic variation due to an ink overlapping (or overlaying) order when printing in a bidirectional mode. Bright color ink dots and dark color ink dots are arranged alternately within the same swath when printing in the bidirectional mode. Plural swaths with different overlapped colors consisting of these dots are arranged alternately in both the main and sub directions to perform overall chromatic averaging.

摘要翻译： 一种喷墨打印机，其能够在以双向模式打印时最小化由于油墨重叠（或重叠）顺序引起的色彩变化。 当以双向模式打印时，明亮的彩色墨点和深色墨点交替排列在相同的条纹内。 由这些点组成的具有不同重叠颜色的多个条纹在主方向和副方向上交替布置，以进行总体色平均化。

公开(公告)号：US06458332B2

公开(公告)日：2002-10-01

申请号：US09801747

申请日：2001-03-09

申请人： Hiroshi Ooshima ,  Hideo Noda

发明人： Hiroshi Ooshima ,  Hideo Noda

IPC分类号： B01D900

CPC分类号： B01F7/00175 ,  B01D9/0013 ,  B01D9/0031 ,  B01F7/00641 ,  B01F7/16 ,  B01F15/065 ,  Y10T117/10

摘要： The invention provides a crystallization apparatus that includes an agitation tank, a liquid circulation means for circulating a liquid or a slurry along a wall of the agitation tank, and one or more temperature difference creation means capable of creating a temperature difference at the wall of the agitation tank, wherein the temperature difference creation means is installed to the agitation tank. The temperature difference creation means is, for example, arranged at a region where liquid or slurry spouted by rotating the liquid spouting device contacts the wall of the agitation tank or a region below that region, and which increases or decreases the temperature of the spouted liquid or slurry compared to the temperature of surrounding liquid or slurry. Since the apparatus with this configuration has a large vaporization area and a large heat transfer area, the induction period for crystal generation can be shortened, and crystals with narrow size distribution and large size can be obtained. Furthermore, it is possible to obtain a specified crystal form, that is, it is possible to control crystal polymorphism.

摘要翻译： 本发明提供了一种结晶装置，其包括搅拌槽，用于使液体或浆料沿着搅拌槽的壁循环的液体循环装置，以及一个或多个温度差产生装置，其能够在所述搅拌槽的壁处产生温度差 搅拌槽，其中温度差产生装置安装到搅拌槽。 例如，温差产生装置设置在通过旋转液体喷射装置而喷射的液体或浆料接触搅拌槽的壁或该区域下方的区域，并且其中喷射液体的温度升高或降低 或浆料与周围液体或浆料的温度相比较。 由于具有这种结构的装置具有大的蒸发面积和大的传热面积，因此可以缩短晶体生成的诱导期，并且可以获得具有窄尺寸分布和大尺寸的晶体。 此外，可以获得指定的晶体形式，即可以控制晶体多晶型。

公开(公告)号：US06334704B2

公开(公告)日：2002-01-01

申请号：US09742181

申请日：2000-12-22

申请人： Hideo Noda ,  Takaya Inoue

发明人： Hideo Noda ,  Takaya Inoue

IPC分类号： B01F510

CPC分类号： B01F7/00591 ,  B01F3/0478

摘要： A liquid ejection apparatus has gutter bodies secured to an agitator shaft at predetermined inclination angles or gutter bodies or tubular bodies attached to these agitator shaft so that the size of the inclination angles are adjustable. The gutter bodies or tubular bodies of the liquid ejection apparatus are revolved around the agitator shaft so that liquid is ejected from the respective upper openings of the gutter bodies or tubular bodies. This liquid is distributed onto the inner surface of a tank, and/or into a space above a liquid surface, thereby washing the inner surface of the tank, maintaining the heat transfer area, and promoting evaporation of the liquid in the tank.

摘要翻译： 液体喷射装置具有以预定倾斜角度固定到搅拌器轴的沟槽体，或者连接到这些搅拌器轴的沟槽体或管状体，使得倾斜角度的大小是可调节的。 液体喷射装置的沟槽体或管状体围绕搅拌器轴旋转，使得液体从沟槽体或管状体的相应上部开口排出。 这种液体分布在罐的内表面上和/或分散在液面之上的空间中，从而洗涤罐的内表面，保持传热面积，并促进液体在罐中的蒸发。