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公开(公告)号：US10597708B2
公开(公告)日：2020-03-24
申请号：US16400023
申请日：2019-04-30
Applicant: Natera, Inc.
Inventor： Bernhard Zimmermann , Matthew Hill , Philippe Lacroute , Michael Dodd , Alexander Wong
IPC: C12Q1/68 , C12Q1/686 , C12Q1/6874 , C12Q1/6883 , C12Q1/6811 , C12Q1/6848
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
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公开(公告)号：US10597709B2
公开(公告)日：2020-03-24
申请号：US16412301
申请日：2019-05-14
Applicant: Natera, Inc.
Inventor： Bernhard Zimmermann , Matthew Hill , Philippe Lacroute , Michael Dodd , Alexander Wong
IPC: C12Q1/68 , C12Q1/686 , C12Q1/6874 , C12Q1/6883 , C12Q1/6811 , C12Q1/6848
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
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公开(公告)号：US20170051355A1
公开(公告)日：2017-02-23
申请号：US14877925
申请日：2015-10-07
Applicant: Natera, Inc.
Inventor： Bernhard Zimmermann , Matthew M. Hill , Philippe Gilbert Lacroute , Michael Dodd
CPC classification number: C12Q1/6886 , C12N15/1089 , C12Q1/68 , C12Q1/6844 , C12Q1/686 , C12Q1/6876 , C12Q1/6883 , C12Q2600/156 , C12Q2600/16 , G16B5/00 , G16B20/00 , G16B30/00 , G16B40/00
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
Abstract translation: 本发明提供了在一个反应体积中同时扩增多个核酸区域的方法以及用于选择用于这种扩增方法的引物文库的方法。 本发明还提供具有所需特征的引物文库，例如扩增引物二聚体或其他非靶扩增子的最小形成。
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公开(公告)号：US20150322507A1
公开(公告)日：2015-11-12
申请号：US14538982
申请日：2014-11-24
Applicant: Natera, Inc.
Inventor： Bernhard Zimmermann , Matthew Hill , Philippe Lacroute , Michael Dodd , Alexander Wong
IPC: C12Q1/68
CPC classification number: C12Q1/686 , C12Q1/68 , C12Q1/6811 , C12Q1/6848 , C12Q1/6874 , C12Q1/6883 , C12Q2600/156 , C12Q2527/107 , C12Q2537/143
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
Abstract translation: 本发明提供了在一个反应体积中同时扩增多个核酸区域的方法以及用于选择用于这种扩增方法的引物文库的方法。 本发明还提供具有所需特征的引物文库，例如扩增引物二聚体或其他非靶扩增子的最小形成。
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公开(公告)号：US20190256894A1
公开(公告)日：2019-08-22
申请号：US16400023
申请日：2019-04-30
Applicant: Natera, Inc.
Inventor： Bernhard Zimmermann , Matthew Hill , Philippe Lacroute , Michael Dodd , Alexander Wong
IPC: C12Q1/686 , C12Q1/6848 , C12Q1/6811 , C12Q1/6874 , C12Q1/6883 , C12Q1/68
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
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Patent Agency Ranking
公开(公告)号：US20170145474A1
公开(公告)日：2017-05-25
申请号：US15336630
申请日：2016-10-27
Applicant: Natera, Inc.
Inventor： Bernhard Zimmermann , Matthew Hill , Philippe Lacroute , Michael Dodd , Alexander Wong
IPC: C12Q1/68
CPC classification number: C12Q1/686 , C12Q1/68 , C12Q1/6811 , C12Q1/6848 , C12Q1/6874 , C12Q1/6883 , C12Q2600/156 , C12Q2527/107 , C12Q2537/143
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
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公开(公告)号：US20140141981A1
公开(公告)日：2014-05-22
申请号：US14171587
申请日：2014-02-03
Applicant: Natera, Inc.
Inventor： Bernhard Zimmermann , Matthew Hill , Philippe Lacroute , Michael Dodd
CPC classification number: C12Q1/6886 , C12N15/1089 , C12Q1/68 , C12Q1/6844 , C12Q1/686 , C12Q1/6876 , C12Q1/6883 , C12Q2600/156 , C12Q2600/16 , G16B5/00 , G16B20/00 , G16B30/00 , G16B40/00
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
Abstract translation: 本发明提供了在一个反应体积中同时扩增多个核酸区域的方法以及用于选择用于这种扩增方法的引物文库的方法。 本发明还提供具有所需特征的引物文库，例如扩增引物二聚体或其他非靶扩增子的最小形成。
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公开(公告)号：US20140094373A1
公开(公告)日：2014-04-03
申请号：US14044434
申请日：2013-10-02
Applicant: Natera, Inc.
Inventor： Berhard Zimmermann , Matthew Hill , Philippe Lacroute , Michael Dodd
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12N15/1089 , C12Q1/68 , C12Q1/6844 , C12Q1/686 , C12Q1/6876 , C12Q1/6883 , C12Q2600/156 , C12Q2600/16 , G16B5/00 , G16B20/00 , G16B30/00 , G16B40/00
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
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公开(公告)号：US11091804B2
公开(公告)日：2021-08-17
申请号：US16752339
申请日：2020-01-24
Applicant: Natera, Inc.
Inventor： Bernhard Zimmermann , Matthew Hill , Philippe Lacroute , Michael Dodd , Alexander Wong
IPC: C12Q1/68 , C12Q1/686 , C12Q1/6874 , C12Q1/6883 , C12Q1/6811 , C12Q1/6848
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
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公开(公告)号：US10351906B2
公开(公告)日：2019-07-16
申请号：US15336630
申请日：2016-10-27
Applicant: Natera, Inc.
Inventor： Bernhard Zimmermann , Matthew Hill , Philippe Lacroute , Michael Dodd , Alexander Wong
IPC: C12Q1/68 , C12Q1/686 , C12Q1/6874 , C12Q1/6883 , C12Q1/6811 , C12Q1/6848
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
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