-
公开(公告)号:US20070075163A1
公开(公告)日:2007-04-05
申请号:US11225723
申请日:2005-09-13
申请人: Alan Smith , Nigel Wood , Michael Thomas
发明人: Alan Smith , Nigel Wood , Michael Thomas
IPC分类号: B05B9/00
CPC分类号: B05B9/0423 , B05B12/085 , B05B12/14 , Y10T137/85954
摘要: A paint circulating system is suitable for providing paint to applicators in a product finishing facility. The system includes a pump for pumping paint around the system and a back-pressure regulator (BPR), which substantially eliminates pressure fluctuations of paint in the system upstream of the BPR. Control means are provided for controlling the pump and the BPR to operate in one of a flow mode, wherein a required flow rate of paint around the system is maintained, and a pressure mode, wherein a pressure of paint between the pump and the BPR is maintained. The paint circulating method includes switching operation of the pump and the BPR between the flow mode and the pressure mode.
摘要翻译: 涂料循环系统适用于在产品整理设备中为涂料提供涂料。 该系统包括用于在系统周围泵送油漆的泵和背压调节器(BPR),其基本上消除了BPR上游系统中油漆的压力波动。 提供了控制装置,用于控制泵和BPR以流动模式之一操作,其中维持系统周围所需的涂料流量;以及压力模式,其中泵和BPR之间的油漆压力为 保持。 涂料循环方法包括在流动模式和压力模式之间的泵的切换操作和BPR。
-
公开(公告)号:US20110158836A1
公开(公告)日:2011-06-30
申请号:US12673578
申请日:2008-08-14
申请人: Nigel Wood , Alan Smith
发明人: Nigel Wood , Alan Smith
IPC分类号: F04B53/12
CPC分类号: F04B53/126 , F04B15/02 , F04B53/1007 , F16K15/044 , F16K15/183
摘要: The invention relates to a liquid paint pumping apparatus comprising a piston reciprocable in a cylinder to pump liquid paint during a substantially horizontal pumping stroke of the piston and to charge the cylinder with paint during a reverse stroke of the piston. The apparatus further comprises a check valve disposed within the piston, the check valve comprising: a ball member, a seat, a spring urging the ball member into engagement with the seat, and a plastics cage guiding movement of the ball towards and away from the seat. The seat receives the ball member so as to form a seal to prevent flow of liquid paint between the ball and the seat during the pumping stroke of the piston, and the ball member moves away from the seat during the reverse stroke of the piston.
摘要翻译: 本发明涉及一种液体涂料泵送装置,其包括可在气缸中往复运动的活塞,用于在活塞的基本水平的泵送冲程期间泵送液体涂料,并且在活塞的反冲程期间向气缸充气。 该装置还包括设置在活塞内的止回阀,该止回阀包括:球部件,座椅,使球部件与座椅相接合的弹簧,以及塑料保持架,其引导球和/ 座位。 座椅接收球部件,以形成密封,以防止在活塞的泵送冲程期间液体涂料在球和座之间流动,并且球件在活塞的反冲程中移动离开座椅。
-
公开(公告)号:US09078814B2
公开(公告)日:2015-07-14
申请号:US13541325
申请日:2012-07-03
IPC分类号: A61F13/00 , A61K31/445 , A01N43/40 , A01N43/16 , A61K31/35 , A61K9/00 , A61K31/4468
CPC分类号: A61K31/4468 , A61K9/0043 , A61K47/26 , A61K47/36 , A61M11/00 , A61M15/08
摘要: An intrasnal spray device contains a composition for the intranasal delivery of fentanyl or a pharmaceutically acceptable salt thereof to an animal includes an aqueous solution of fentanyl or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable additive selected from (i) a pectin and (ii) a poloxamer and chitosan or a salt or derivative thereof; provided that when the composition comprises a pectin it is substantially free of divalent metal ions; and which, in comparison to a simple aqueous solution of fentanyl administered intranasally at the same dose, provides a peak plasma concentration of fentanyl (Cmax) that is from 10 to 80% of that achieved using a simple aqueous solution of fentanyl administered intranasally at an identical fentanyl dose. A method for treating or managing pain by intranasally administering the composition is also disclosed.
摘要翻译: 包含用于将芬太尼或其药学上可接受的盐鼻内递送给动物的组合物包括芬太尼或其药学上可接受的盐的水溶液和选自以下的药学上可接受的添加剂:(i)果胶和(ii) 泊洛沙姆和壳聚糖或其盐或衍生物; 条件是当组合物包含果胶时,其基本上不含二价金属离子; 并且与以相同剂量鼻内施用的芬太尼的简单水溶液相比,提供了芬太尼(C max)的峰值血浆浓度,其为使用芬太尼简单的水溶液,其在鼻内给药时的10至80% 芬太尼剂量相同。 还公开了通过鼻内施用组合物治疗或治疗疼痛的方法。
-
公开(公告)号:US08710028B2
公开(公告)日:2014-04-29
申请号:US12675306
申请日:2008-08-29
申请人: Peter James Watts , Yu-Hui Cheng , Alan Smith , Jonathan Castile
发明人: Peter James Watts , Yu-Hui Cheng , Alan Smith , Jonathan Castile
CPC分类号: A61K9/0043 , A61K9/146 , A61K9/1652 , A61K9/1694 , A61K9/19 , A61K31/5513 , A61K31/5517
摘要: A powder composition for intranasal delivery includes a benzodiazepine drug and chitosan, a salt of chitosan, a derivative of chitosan or a salt of a derivative of chitosan.
摘要翻译: 用于鼻内递送的粉末组合物包括苯并二氮杂药物和壳聚糖,壳聚糖的盐,壳聚糖的衍生物或壳聚糖的衍生物的盐。
-
5.
公开(公告)号:US08709996B2
公开(公告)日:2014-04-29
申请号:US12766487
申请日:2010-04-23
申请人: Michael Leane , Alan Smith , Lisbeth Illum
发明人: Michael Leane , Alan Smith , Lisbeth Illum
IPC分类号: A61K31/722 , A61K38/28 , A61K38/16 , A61K33/42 , A61K38/12 , A61K38/21 , A61K38/20 , A61K9/48
CPC分类号: A61K9/4808 , A61K9/1617 , A61K9/1652 , A61K9/205 , A61K9/5047 , A61K9/5084 , A61K31/19 , A61K31/722 , A61K38/00
摘要: The present invention provides a solid composition for oral administration comprising: (i) a drug compound; (ii) chitosan or a derivative thereof or a salt of chitosan or salt of a derivative of chitosan; and (iii) an organic acid. Preferably the drug compound is a polar molecule having a molecular weight of 1 KDa or less, a peptide, a protein or a polysaccharide. The compositions of the invention provide enhance absorption of the drug compound.
摘要翻译: 本发明提供一种用于口服给药的固体组合物,其包含:(i)药物化合物; (ii)壳聚糖或其衍生物或壳聚糖的盐或壳聚糖衍生物的盐; 和(iii)有机酸。 优选地,药物化合物是分子量为1KDa或更小的极性分子,肽,蛋白质或多糖。 本发明的组合物提供药物化合物的增强吸收。
-
公开(公告)号:US07947257B2
公开(公告)日:2011-05-24
申请号:US11004556
申请日:2004-12-03
申请人: Peter James Watts , Alan Smith , Jonathan Castile
发明人: Peter James Watts , Alan Smith , Jonathan Castile
CPC分类号: A61K9/0043 , A61K31/435
摘要: Compositions are provided for the intranasal administration of granisetron or a pharmaceutically acceptable salt thereof. Preferred compositions are in the form of an aqueous solution. Optionally, the compositions comprise chitosan, a salt or derivative thereof or a salt of a derivative of chitosan. The compositions can be used for the treatment or prevention of nausea and/or vomiting.
摘要翻译: 提供了用于格拉司琼或其药学上可接受的盐的鼻内给药的组合物。 优选的组合物是水溶液的形式。 任选地,组合物包含壳聚糖,其盐或衍生物或壳聚糖衍生物的盐。 该组合物可用于治疗或预防恶心和/或呕吐。
-
公开(公告)号:US07384396B2
公开(公告)日:2008-06-10
申请号:US10435221
申请日:2003-05-08
IPC分类号: A61B5/00
CPC分类号: A61B5/14514 , A61B5/00 , A61B5/0002 , A61B5/14532 , A61B5/150022 , A61B5/150099 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/150862 , A61B5/150969 , A61B5/150984 , A61B5/15134 , A61B5/155 , A61B5/157 , A61B10/0045 , A61B2010/008
摘要: A system and method for extracting a biological fluid from an organism and continuously monitoring its characteristics. The system includes a tissue interface device suitable for positioning on or about the surface of the biological membrane of the organism and a monitor and control unit coupled to the tissue interface device. The tissue interface device includes a sensor positioned in a flow path of the fluid for continuously sensing a characteristic of the biological fluid as it flows out from the one or more artificial openings formed in the biological membrane. The sensor generates a sensor signal representative thereof. The monitor and control unit electrically or optically reads the sensor to obtain a measurement of a characteristic, such as concentration of a particular analyte, of the biological fluid on a continuous basis.
摘要翻译: 一种用于从生物体提取生物流体并连续监测其特征的系统和方法。 该系统包括适于定位在生物体的生物膜的表面上或周围的组织界面装置以及耦合到组织界面装置的监测和控制单元。 组织接口装置包括定位在流体的流动路径中的传感器,用于在生物流体从形成在生物膜中的一个或多个人造开口流出时持续感测生物流体的特性。 传感器产生代表其的传感器信号。 监视器和控制单元以电或光学方式读取传感器,以连续的方式获得生物流体特性的浓度,例如特定分析物的浓度。
-
公开(公告)号:US20060214592A1
公开(公告)日:2006-09-28
申请号:US11091350
申请日:2005-03-28
申请人: William Hopkins , Anthony Banks , Alan Smith , Louis Pickvet , Robert Towe , Charles Schlemm
发明人: William Hopkins , Anthony Banks , Alan Smith , Louis Pickvet , Robert Towe , Charles Schlemm
IPC分类号: H01J13/46
CPC分类号: H05B41/00
摘要: A gas discharge lamp power supply having a base, a pair of opposed side walls extending from the base, and opposed first and second end walls extending from the base between the opposed side walls. The first end wall has a sloped wall extending angularly between the side walls, and two input terminals are mounted on the sloped wall. In another embodiment, the power supply has a control with a nonvolatile memory for storing an error code in response to a detected fault condition, thereby permitting the error code to be displayed upon power being removed from and then, subsequently reapplied.
摘要翻译: 一种气体放电灯电源,具有基座,从基座延伸的一对相对的侧壁,以及在相对的侧壁之间从基部延伸的相对的第一和第二端壁。 第一端壁具有在侧壁之间成角度延伸的倾斜壁,并且两个输入端子安装在倾斜壁上。 在另一个实施例中,电源具有用于响应于检测到的故障状况而存储错误代码的非易失性存储器的控制,从而允许在从被重新施加电力并随后被重新应用的电力时显示错误代码。
-
9.
公开(公告)号:US20060189857A1
公开(公告)日:2006-08-24
申请号:US11412491
申请日:2006-04-27
申请人: Mark Faupel , Raulee Marcus , Alan Smith , Difei Yang
发明人: Mark Faupel , Raulee Marcus , Alan Smith , Difei Yang
IPC分类号: A61B5/00
CPC分类号: A61B5/145 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/441 , A61B5/4839
摘要: The present invention relates to a system and method for monitoring or treating a health condition. The method can include accessing a biological fluid, evaluating an analyte in the fluid, presenting a measurement parameter based on the evaluation, and/or administering a treatment based on the evaluation. The measurement parameter can prompt administering a treatment. The system can include a fluid handling device, a display and/or alert device, and/or an administration device. This abstract is provided for searching purposes only and is not meant for construing the claims.
摘要翻译: 本发明涉及一种用于监测或治疗健康状况的系统和方法。 该方法可以包括进入生物流体,评估流体中的分析物,基于评估呈现测量参数,和/或基于评估进行治疗。 测量参数可以促进治疗。 该系统可以包括流体处理装置,显示器和/或警报装置,和/或管理装置。 本摘要仅用于搜索目的,而不是用于解释权利要求。
-
公开(公告)号:US20060129871A1
公开(公告)日:2006-06-15
申请号:US10999452
申请日:2004-11-30
申请人: Alan Smith
发明人: Alan Smith
IPC分类号: G06F11/00
CPC分类号: G06F11/3476 , G06F17/30569 , Y10S707/99945 , Y10S707/99948
摘要: An apparatus, system, and method are disclosed for analyzing trace data that facilitates the analysis by minimizing extraneous results presented to a user. The apparatus includes a user interface to define a query expression based on a condition and one or more parameters and to display a report of trace entries satisfying the query expression. A record handler retrieves an unstructured trace record from a storage device or database. A structuring module divides the unstructured trace record logically into two or more trace entries based on structural information. A comparison module applies the query expression to each entry. This application of the query expression may include further sub-dividing the entry logically to search on a sub-entry level. The comparison module assembles entries satisfying the query expression into an abridged trace record. A report engine combines the abridged trace records into a report of trace entries satisfying the query expression.
摘要翻译: 公开了一种用于分析跟踪数据的装置,系统和方法,用于通过使提供给用户的外部结果最小化来便于分析。 该装置包括用户界面,用于基于条件和一个或多个参数定义查询表达式,并显示满足查询表达式的跟踪条目的报告。 记录处理程序从存储设备或数据库中检索非结构化跟踪记录。 结构化模块基于结构信息将非结构化跟踪记录逻辑地分成两个或多个跟踪条目。 比较模块将查询表达式应用于每个条目。 查询表达式的该应用可以包括在逻辑上进一步细分条目以在子条目级上搜索。 比较模块将满足查询表达式的条目汇编成一条精简的跟踪记录。 报告引擎将简化的跟踪记录合并到满足查询表达式的跟踪条目的报告中。
-
-
-
-
-
-
-
-
-