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28 条记录 (耗时 0.018 秒)

    3-carbamoyl-4-hydroxy-coumarins for combating parasitic heiminths
    1.
    发明授权
    3-carbamoyl-4-hydroxy-coumarins for combating parasitic heiminths 失效
    3-氨基甲酰基-4-羟基香豆素，用于防治寄生性重锤

    公开(公告)号：US4766144A

    公开(公告)日：1988-08-23

    申请号：US35543

    申请日：1987-04-03

    申请人： Nikolaus Muller ,  Eckart Kranz ,  Peter Andrews

    发明人： Nikolaus Muller ,  Eckart Kranz ,  Peter Andrews

    IPC分类号： A61K31/37 ,  A61K31/443 ,  A61K31/445 ,  A61P33/00 ,  C07D311/56 ,  C07D405/12 ,  C07D311/12

    CPC分类号： C07D405/12 ,  C07D311/56

    摘要： 3-carbamoyl-4-hydroxy-couramins for combating parasitic helminths of the formula ##STR1## in which R.sup.1 represents hydrogen, halogen, alkyl, NO.sub.2, CN or alkoxy,X represents O, S, SO or SO.sub.2R.sup.2 represents alkyl, halogenoalkyl, phenyl, naphthyl or pyridyl, which can optionally be substituted; or the radical -X-R.sup.2, together with the radical R.sup.3 can also form an alkylenedioxy (-O-alk-O), halogenoalkylenedioxy, oxyalkyleneoxyalkylene (-O-Alk-O-Alk-) or oxyhalogenoalkylene-oxyhalogenoalkylene bridge; andR.sup.3 and R.sup.4 independently of one another represent hydrogen, halogen, CN, OH, NO.sub.2, amino, mono- or dialklylamino, alkyl, halogenoalkyl, aralkyl or aryl, which can optionally be substituted,can be used for combating parasitic helminths.

    摘要翻译： 3-氨基甲酰基-4-羟基维生素，用于对抗式为“IMAGE”的寄生蠕虫，其中R 1表示氢，卤素，烷基，NO 2，CN或烷氧基，X表示O，S，SO或SO 2 R 2表示烷基，卤代烷基， 苯基，萘基或吡啶基，其可任选被取代; 或基团-X-R2与基团R3一起也可以形成亚烷基二氧基（-O-烷基-O），卤代亚烷基二氧基，氧亚烷基氧化烯（-O-Alk-O-Alk-）或氧卤代亚烷基 - 氧卤代亚烷基桥; 并且R 3和R 4彼此独立地表示氢，卤素，CN，OH，NO 2，氨基，单或二烷基氨基，烷基，卤代烷基，芳烷基或芳基，其可任选被取代，可用于对抗寄生蠕虫。

    Herbicidally active substituted 6-halogeno-tert.-butyl-1,2,4-triazin-5-ones
    2.
    发明授权
    Herbicidally active substituted 6-halogeno-tert.-butyl-1,2,4-triazin-5-ones 失效
    除草活性的取代的6-卤代叔丁基-1,2,4-三嗪-5-酮

    公开(公告)号：US4386953A

    公开(公告)日：1983-06-07

    申请号：US299919

    申请日：1981-09-08

    申请人： Eckart Kranz ,  Kurt Findeisen ,  Robert Schmidt ,  Ludwig Eue

    发明人： Eckart Kranz ,  Kurt Findeisen ,  Robert Schmidt ,  Ludwig Eue

    IPC分类号： C07D253/06 ,  A01N43/707 ,  C07D253/075 ,  A01N43/64

    CPC分类号： C07D253/075 ,  A01N43/707

    摘要： A substituted 6-halogeno-tert.-butyl-1,2,4-triazin-5-one of the formula ##STR1## in which R.sup.1 is an amino or methyl group,R.sup.2 is an alkylmercapto, alkylamino or dialkylamino group,X is a halogen atom, andY and Z each independently is a hydrogen or halogen atom,which possesses selective herbicidal activity. A synthesis involving the novel intermediates ##STR2## in which X, Y and Z have the above-mentioned meaning andQ is CN, CONH.sub.2 or COOH,is also shown.

    摘要翻译： R 1为氨基或甲基的取代的6-卤代叔丁基-1,2,4-三嗪-5-酮，其中R 1为烷基巯基，烷基氨基或二烷基氨基，X为 卤素原子，Y和Z各自独立地为具有选择性除草活性的氢或卤素原子。 涉及其中X，Y和Z具有上述含义且Q为CN，CONH 2或COOH的新中间体“IMAGE”的合成也显示。

    Preparation of phosphorylated amidines
    3.
    发明授权
    Preparation of phosphorylated amidines 失效
    磷酸化脒的制备

    公开(公告)号：US4162280A

    公开(公告)日：1979-07-24

    申请号：US887899

    申请日：1978-03-17

    申请人： Eckart Kranz

    发明人： Eckart Kranz

    IPC分类号： A01N57/26 ,  B01J27/00 ,  B01J31/00 ,  C07F9/24 ,  C07F9/44

    CPC分类号： A01N57/26 ,  C07F9/2458

    摘要： Preparation of a phosphorylated amidine of the formula ##STR1## wherein X is oxygen or sulfur and R, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are various organic radicals, which comprises reacting a phosphoric acid ester-amide of the formula ##STR2## with a carboxamide of the formula ##STR3## at a temperature between about 0.degree. and 50.degree. C., and then reacting the mixture with a base. Advantageously the reaction is effected at about 0.degree. to 15.degree. C. in the presence of an aliphatic or aromatic optionally chlorinated hydrocarbon or an alcohol as an inert solvent, and in the presence of a catalyst.

    摘要翻译： 制备式IMAMA的磷酸化脒，其中X是氧或硫，R，R 1，R 2，R 3和R 4是各种有机基团，其包括使下式的磷酸酯 - 酰胺与羧酰胺 在约0℃至50℃之间的温度下，使式“IMAGE”进行反应，然后使该混合物与碱反应。 有利地，反应在约0℃至15℃下在脂族或芳族任选氯化烃或作为惰性溶剂的醇存在下进行，并在催化剂存在下进行。

    Preparation of 4-alkylthiosemicarbazides
    4.
    发明授权
    Preparation of 4-alkylthiosemicarbazides 失效
    4-烷基硫代氨基脲的制备

    公开(公告)号：US4132736A

    公开(公告)日：1979-01-02

    申请号：US729933

    申请日：1976-10-06

    申请人： Gunther Cramm ,  Eckart Kranz ,  Gunter Hellrung

    发明人： Gunther Cramm ,  Eckart Kranz ,  Gunter Hellrung

    IPC分类号： C07B61/00 ,  B01J27/00 ,  C07C67/00 ,  C07C325/00 ,  C07C337/06 ,  C07D285/12 ,  C07D285/135 ,  C07C159/00

    CPC分类号： C07D285/135

    摘要： 4-Alkylthiosemicarbazides of the formulaAlkyl--NH--CS--NH--NH.sub.2are produced by heating at about 40 to 90.degree. C the novel hydrazinium salts of N-alkyldithiocarbamic acids of the formulaAlkyl--NH--CS--S.sup.- + NH.sub.3 --NH.sub.2in a solvent while removing by-product H.sub.2 S as by use of vacuum or passage of an inert gas through the reaction mixture, advantageously in the presence of a catalytic amount of sulfur to speed up the reaction. Hydrazine hydrate may also be present. The hydrazinium salt starting material can be prepared by reacting the corresponding alkylamine, ammonia, carbon disulfide and hydrazine, and the reaction solution directly employed in the heating step of the present invention without isolation of the intermediate.

    摘要翻译： 通过在约40至90℃下加热式烷基-NH-CS-S-NH-NH 2的N-烷基二硫代氨基甲酸的新的肼鎓盐，制备式烷基-NH-CS-NH-NH 2的4-烷基硫代氨基脲 在溶剂中，同时通过使用真空或通过惰性气体通过反应混合物除去副产物H 2 S，有利地在催化量的硫存在下加速反应。 也可以存在水合肼。 肼盐起始原料可以通过使相应的烷基胺，氨，二硫化碳和肼与本发明的加热步骤中直接使用的反应溶液反应而不分离中间体来制备。

    Preparation of 1-azolyl-3,3-dimethyl-1-phenoxy-butan-2-ols
    7.
    发明授权
    Preparation of 1-azolyl-3,3-dimethyl-1-phenoxy-butan-2-ols 失效
    1-噻唑基-3,3-二甲基-1-苯氧基 - 丁-2-醇的制备

    公开(公告)号：US4371700A

    公开(公告)日：1983-02-01

    申请号：US232461

    申请日：1981-02-09

    申请人： Eckart Kranz

    发明人： Eckart Kranz

    IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D233/60 ,  C07D233/64 ,  C07D249/08 ,  C07D521/00

    CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D249/08

    摘要： A process for the preparation of a 1-azolyl-3,3-dimethyl-1-phenoxy-butan-2-ol of the formula ##STR1## in which X is a nitrogen atom or a CH group,Y each independently is halogen, phenyl, phenoxy, nitro, alkyl, alkoxy or cycloalkyl, andn is 0, 1, 2 or 3,comprising reacting a 1-azolyl-3,3-dimethyl-1-phenoxy-butan-2-one of the formula ##STR2## with formic acid/triethylamine in the form of a 5:2 addition compound of the formula5HCOOHx2N(C.sub.2 H.sub.5).sub.3.The product is a known fungicide.

    摘要翻译： 制备其中X为氮原子或CH基团的式“IMAGE”的1-吡唑基-3,3-二甲基-1-苯氧基 - 丁-2-醇的方法Y各自独立地为卤素， 苯基，苯氧基，硝基，烷基，烷氧基或环烷基，n为0,1,2或3，包括使式（I）的1-吡唑基-3,3-二甲基-1-苯氧基 - 丁-2-酮 与甲酸/三乙胺以5:2式5HCOOH 2 N（C 2 H 5）3的加成化合物的形式存在。 该产品是已知的杀真菌剂。

    Combating fungi with .alpha.-azolyl-keto derivatives
    8.
    发明授权
    Combating fungi with .alpha.-azolyl-keto derivatives 失效
    抗真菌与α-唑基 - 酮衍生物

    公开(公告)号：US4316932A

    公开(公告)日：1982-02-23

    申请号：US54067

    申请日：1979-07-02

    申请人： Eckart Kranz ,  Wolfgang Kramer ,  Karl H. Buchel ,  Wilhelm Brandes ,  Paul-Ernst Frohberger

    发明人： Eckart Kranz ,  Wolfgang Kramer ,  Karl H. Buchel ,  Wilhelm Brandes ,  Paul-Ernst Frohberger

    IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00 ,  A01N43/82

    CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

    摘要： An .alpha.-azolyl-keto derivative of the formula ##STR1## in which R.sup.1 represents optionally substituted alkyl or optionally substituted phenyl,R.sup.2 represents the grouping --CX.sup.1 X.sup.2 R.sup.3 or alkoxy-carbonyl,R.sup.3 represents halogen, halogenoalkyl or optionally substituted phenyl,R.sup.4 represents the grouping --O--CO--R.sup.5, --O(S)--R.sup.6 or --O--S(O).sub.n --R.sup.7, or alkylamino, dialkylamino, optionally substituted phenylamino or halogen,R.sup.5 represents alkyl, halogenoalkyl, alkenyl, alkynyl, cycloalkyl, optionally substituted phenyl, optionally substituted phenylalkyl, alkylamino, dialkylamino or optionally substituted phenylamino,R.sup.6 represents alkyl, alkenyl, alkynyl, cycloalkyl, optionally substituted phenyl or optionally substituted benzyl,R.sup.7 represents alkyl, halogenoalkyl, optionally substituted phenyl or dialkylamino,n represents 1 or 2,X.sup.1 and X.sup.2 each independently represents hydrogen or halogen, andY represents a nitrogen atom or the CH group, or a physiologically acceptable acid addition salt or metal salt complex thereof, which possesses fungicidal properties.

    摘要翻译： 其中R 1表示任意取代的烷基或任意取代的苯基，R 2代表基团-CX 1 X 2 R 3或烷氧基 - 羰基，R 3表示卤素，卤代烷基或任意取代的苯基，R 4代表基团 -O-CO-R 5，-O（S）-R 6或-OS（O）n -R 7或烷基氨基，二烷基氨基，任选取代的苯基氨基或卤素，R 5表示烷基，卤代烷基，烯基，炔基，环烷基，任选取代的苯基 ，任选取代的苯基烷基，烷基氨基，二烷基氨基或任选取代的苯基氨基，R 6表示烷基，烯基，炔基，环烷基，任选取代的苯基或任选取代的苄基，R 7表示烷基，卤代烷基，任选取代的苯基或二烷基氨基，n表示1或2， 和X2各自独立地表示氢或卤素，Y表示氮原子或CH基团，或生理上可接受的酸加成盐或金属盐c 其复合物具有杀真菌性能。

    1-Phenyl-substituted 1,3,5-triazines
    10.
    发明授权
    1-Phenyl-substituted 1,3,5-triazines 失效
    1-苯基取代的1,3,5-三嗪

    公开(公告)号：US3948893A

    公开(公告)日：1976-04-06

    申请号：US452140

    申请日：1974-03-18

    申请人： Gerd Aichinger ,  Axel Haberkorn ,  Heinrich Kolling ,  Eckart Kranz ,  Josef Reisdorff

    发明人： Gerd Aichinger ,  Axel Haberkorn ,  Heinrich Kolling ,  Eckart Kranz ,  Josef Reisdorff

    IPC分类号： C07D251/34 ,  A23K1/16 ,  A61K31/53 ,  C07C317/42 ,  C07C323/44 ,  C07C323/66 ,  C07D209/48 ,  C07D251/04 ,  C07D251/38 ,  C07D51/26

    CPC分类号： C07D209/48 ,  A23K20/116 ,  C07C317/42 ,  C07C323/44 ,  C07C323/66

    摘要： 1-Phenyl-substituted 1,3,5-triazines of the formula: ##SPC1##And pharmaceutically acceptable nontoxic salts thereof whereinR.sub.1, r.sub.2, r.sub.3, r.sub.4, r.sub.5, r.sub.6, r.sub.7, r.sub.8 and R.sub.9 are the same or different and each is selected from the group consisting of hydrogen, straight or branched chain alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, halogen, nitro, cyano, amino, acylamino, alkoxycarbonylamino, carboxy, alkoxycarbonyl, carbamoyl, acyl, haloacyl, alkylsulphinyl, alkylsulphonyl, haloalkylsulphonyl and sulphamoyl;R.sub.10 is hydrogen, straight or branched chain alkyl, cycloalkyl, haloalkyl, alkoxy, alkoxyalkyl, haloalkoxyalkyl, alkylthioalkyl, haloalkylthioalkyl, alkenyl, alkynyl, alkoxycarbonyl, (alkylthio)carbonyl, (alkylthio)thiocarbonyl, acylamino, diacylamino, amino, dialkylamino, polymethyleneimino, polymethyleneimino interrupted by a heteroatom in the chain, or unsubstituted or substituted benzyl or aryl;R.sub.11 is hydrogen, or alkyl;X is sulphur, sulphinyl, or sulphonyl; andY is oxygen or sulphur,Are useful for their activity against coccidiosis in humans and animals.

    摘要翻译： 具有下式的1-苯基取代的1,3,5-三嗪：