公开(公告)号：US20120283178A1

公开(公告)日：2012-11-08

申请号：US13517109

申请日：2010-02-26

申请人： Nobuo Tsuruoka ,  Yoshinori Beppu ,  Hirofumi Kouda ,  Hiroshi Watanabe

发明人： Nobuo Tsuruoka ,  Yoshinori Beppu ,  Hirofumi Kouda ,  Hiroshi Watanabe

IPC分类号： C07K5/12 ,  A61P3/04 ,  A61P25/22 ,  A61P25/20 ,  A61K38/12 ,  A61P25/24

CPC分类号： A61K38/12 ,  A23L2/52 ,  A23L33/18 ,  A23V2002/00 ,  A61K9/0053 ,  A61K31/496 ,  A61K31/498

摘要： The present invention aims to provide antidepressants which are free from the problem of side effects and are excellent in safety. The present invention also aims to provide learning motivation improvers which are useful for improvement of learning motivation and can be ingested continuously.The present invention provides antidepressants and learning motivation improvers, each comprising a cyclic dipeptide with the 2,5-diketopiperazine structure as an active ingredient.

摘要翻译： 本发明的目的在于提供不含副作用的问题的抗抑郁药，安全性优异。 本发明还旨在提供一种学习动机改进者，其对于改善学习动机是有用的，并且可以持续摄取。 本发明提供抗抑郁药和学习动机改善剂，每一种都包含具有2,5-二酮哌嗪结构的环状二肽作为活性成分。

公开(公告)号：US20100150890A1

公开(公告)日：2010-06-17

申请号：US12593438

申请日：2008-03-28

申请人： Yoshinori Beppu ,  Nobuo Tsuruoka ,  Tomohiro Rogi ,  Hajime Komura ,  Katsuya Nagai

发明人： Yoshinori Beppu ,  Nobuo Tsuruoka ,  Tomohiro Rogi ,  Hajime Komura ,  Katsuya Nagai

IPC分类号： A61K35/74 ,  A61K31/35 ,  A61K35/66

CPC分类号： C12N1/14 ,  A23F5/02

摘要： It is intended to provide a safe composition for preventing or treating obesity or related complications which has an autonomic nervous control effect, in particular, an effect of enhancing sympathetic nervous activity and an effect of promoting energy metabolism. Thus, a medicinal composition, a food or a drink containing 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one and having an autonomic nervous control effect and an effect of promoting energy metabolism is provided.

摘要翻译： 本发明旨在提供一种用于预防或治疗具有自主神经控制作用的肥胖或相关并发症的安全组合物，特别是增强交感神经活性和促进能量代谢的作用。 因此，含有2,3-二氢-3,5-二羟基-6-甲基-4H-吡喃-4-酮的药物组合物，食品或饮料具有自主神经控制作用和促进能量代谢的作用是 提供。

公开(公告)号：US08492442B2

公开(公告)日：2013-07-23

申请号：US12593468

申请日：2008-03-28

申请人： Yoshinori Beppu ,  Nobuo Tsuruoka ,  Hajime Komura ,  Katsuya Nagai

发明人： Yoshinori Beppu ,  Nobuo Tsuruoka ,  Hajime Komura ,  Katsuya Nagai

IPC分类号： A01N31/00 ,  A61K31/10 ,  C07C63/00 ,  C07C65/00

CPC分类号： A61K35/747 ,  A23L33/10 ,  A23V2002/00 ,  A61K31/19 ,  A61K35/744 ,  A61K35/745 ,  A23V2250/042 ,  A23V2200/322

摘要： It is intended to provide a safe composition for treating a disease or condition relating to autonomic nervous activity which has an autonomic nervous control effect; in particular, an effect of enhancing parasympathetic nervous activity. Thus, a medicinal composition, a food or a drink containing L-phenyl lactic acid and/or D-phenyl lactic acid and having an autonomic nervous control effect is provided.

摘要翻译： 旨在提供一种用于治疗与具有自主神经控制作用的自主神经活动有关的疾病或病症的安全组合物; 特别是增强副交感神经活动的作用。 因此，提供了含有L-苯基乳酸和/或D-苯基乳酸并具有自主神经控制作用的药物组合物，食品或饮料。

公开(公告)号：US08669267B2

公开(公告)日：2014-03-11

申请号：US13059819

申请日：2009-08-06

申请人： Yoshinori Beppu ,  Nobuo Tsuruoka ,  Hajime Komura

发明人： Yoshinori Beppu ,  Nobuo Tsuruoka ,  Hajime Komura

IPC分类号： A01N43/42 ,  A61K31/44 ,  C07D471/00

CPC分类号： C07D471/04 ,  A23C9/1307 ,  A23F5/243 ,  A23G9/32 ,  A23L2/02 ,  A23L2/52 ,  A23L33/10 ,  A23V2002/00 ,  A61K31/473 ,  A61K35/74 ,  C12G3/04 ,  A23V2200/3204 ,  A23V2250/032 ,  A23V2250/606 ,  A23V2250/5072 ,  A23V2200/31

摘要： There is provided a pharmaceutical agent, food, or beverage for treating or preventing a disease or condition that can be ameliorated by inhibiting serotonin reuptake, comprising a clinically-effective amount of (1S,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid.

摘要翻译： 提供了用于治疗或预防可以通过抑制血清素再摄取而改善的疾病或病症的药剂，食品或饮料，其包含临床有效量的（1S，3S）-1-甲基-1,2,3 ，4-四氢-β-咔啉-3-羧酸。

公开(公告)号：US20110152309A1

公开(公告)日：2011-06-23

申请号：US13059819

申请日：2009-08-06

申请人： Yoshinori Beppu ,  Nobuo Tsuruoka ,  Hajime Komura

发明人： Yoshinori Beppu ,  Nobuo Tsuruoka ,  Hajime Komura

IPC分类号： A61K31/437 ,  C07D471/04 ,  C12N1/20 ,  C12P13/04 ,  A61P25/24

CPC分类号： C07D471/04 ,  A23C9/1307 ,  A23F5/243 ,  A23G9/32 ,  A23L2/02 ,  A23L2/52 ,  A23L33/10 ,  A23V2002/00 ,  A61K31/473 ,  A61K35/74 ,  C12G3/04 ,  A23V2200/3204 ,  A23V2250/032 ,  A23V2250/606 ,  A23V2250/5072 ,  A23V2200/31

摘要： There is provided a pharmaceutical agent, food, or beverage for treating or preventing a disease or condition that can be ameliorated by inhibiting serotonin reuptake, comprising a clinically-effective amount of (1S,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid.

摘要翻译： 提供了用于治疗或预防可通过抑制血清素再摄取而改善的疾病或病症的药剂，食品或饮料，其包含临床有效量的（1S，3S）-1-甲基-1,2,3 ，4-四氢 - 咔啉-3-羧酸。

公开(公告)号：US20100150891A1

公开(公告)日：2010-06-17

申请号：US12593468

申请日：2008-03-28

申请人： Yoshinori Beppu ,  Nobuo Tsuruoka ,  Hajime Komura ,  Katsuya Nagai

发明人： Yoshinori Beppu ,  Nobuo Tsuruoka ,  Hajime Komura ,  Katsuya Nagai

IPC分类号： A61K31/192 ,  A61K35/74 ,  A61P25/00 ,  C12P7/42

CPC分类号： A61K35/747 ,  A23L33/10 ,  A23V2002/00 ,  A61K31/19 ,  A61K35/744 ,  A61K35/745 ,  A23V2250/042 ,  A23V2200/322

摘要： It is intended to provide a safe composition for treating a disease or condition relating to autonomic nervous activity which has an autonomic nervous control effect; in particular, an effect of enhancing parasympathetic nervous activity. Thus, a medicinal composition, a food or a drink containing L-phenyl lactic acid and/or D-phenyl lactic acid and having an autonomic nervous control effect is provided.

摘要翻译： 旨在提供一种用于治疗与具有自主神经控制作用的自主神经活动有关的疾病或病症的安全组合物; 特别是增强副交感神经活动的作用。 因此，提供了含有L-苯基乳酸和/或D-苯基乳酸并具有自主神经控制作用的药物组合物，食品或饮料。

公开(公告)号：US08414020B2

公开(公告)日：2013-04-09

申请号：US13054424

申请日：2009-07-07

申请人： Yoshinori Beppu ,  Hidenori Suzuki ,  Tsubana Nakamura ,  Akihiko Narui

发明人： Yoshinori Beppu ,  Hidenori Suzuki ,  Tsubana Nakamura ,  Akihiko Narui

IPC分类号： B60R21/232 ,  B60R21/2334 ,  B60R21/237 ,  B60R21/201 ,  B60R21/213

CPC分类号： B60R21/232 ,  B60R21/201 ,  B60R21/233 ,  B60R21/2334 ,  B60R21/237 ,  B60R2021/161

摘要： An object of the present invention is to ensure smooth deployment of an airbag having a turned-back end portion. The present invention is an airbag device that expands and deploys in a curtain shape on a side portion of a vehicle interior in order to protect an occupant of the vehicle interior, where the airbag includes a gas generator for generating an expansion gas and an airbag that deploys when it is expanded by the gas supplied from the gas generator. The airbag is compressed into an elongated shape when stowed and an end portion of the elongated airbag is turned back in a lengthwise direction, thereby forming an airbag main portion that is not turned back and the turned-back end portion. A restricting member is also provided to restrict deployment of the turned-back end portion of the airbag toward a vehicle outer side when the device is activated.

摘要翻译： 本发明的目的是确保具有折回端部的气囊的平滑展开。 本发明是一种气囊装置，其在车辆内部的侧部以窗帘形状展开和展开，以保护车辆内部的乘客，其中，该气囊包括用于产生膨胀气体的气体发生器和气囊， 当通过从气体发生器供应的气体膨胀时展开。 收纳时气囊被压缩成细长形状，并且细长气囊的端部在长度方向上回转，从而形成未折返的气囊主体部分和后端部。 还设置有限制构件，以在装置被启动时限制安全气囊的后端部向车辆外侧的展开。

公开(公告)号：US10668885B2

公开(公告)日：2020-06-02

申请号：US15816502

申请日：2017-11-17

申请人： Seiji Hioda ,  Yoshinori Beppu ,  Atsushi Yamada ,  Takuya Sudo

发明人： Seiji Hioda ,  Yoshinori Beppu ,  Atsushi Yamada ,  Takuya Sudo

IPC分类号： B60R21/21 ,  B60R21/2165 ,  B60R21/239 ,  B60R21/231 ,  B60R21/215 ,  B60R21/00 ,  B60R21/235 ,  B60R21/23 ,  B60R21/233

摘要： A side airbag device for a rear seat relating to the technique of the present disclosure includes: an airbag module that is provided at an interior of a side garnish that is disposed between a vehicle body side portion and a vehicle transverse direction outer side of a seatback of a rear seat; a tubular flow regulating cloth that is provided at an interior of a side airbag of the airbag module, at a periphery of an inflator; and an airbag door that is provided at the side garnish, and that has a hinge portion and a tear portion at a periphery thereof, and that is pushed by the tubular flow regulating cloth when gas is generated from the inflator, wherein the tubular flow regulating cloth has openings at both ends thereof, and has exhaust holes in a peripheral wall thereof.

公开(公告)号：US20180194318A1

公开(公告)日：2018-07-12

申请号：US15816502

申请日：2017-11-17

申请人： Seiji Hioda ,  Yoshinori Beppu ,  Atsushi Yamada ,  Takuya Sudo

发明人： Seiji Hioda ,  Yoshinori Beppu ,  Atsushi Yamada ,  Takuya Sudo

IPC分类号： B60R21/21 ,  B60R21/2165 ,  B60R21/239 ,  B60R21/231

摘要： A side airbag device for a rear seat relating to the technique of the present disclosure includes: an airbag module that is provided at an interior of a side garnish that is disposed between a vehicle body side portion and a vehicle transverse direction outer side of a seatback of a rear seat; a tubular flow regulating cloth that is provided at an interior of a side airbag of the airbag module, at a periphery of an inflator; and an airbag door that is provided at the side garnish, and that has a hinge portion and a tear portion at a periphery thereof, and that is pushed by the tubular flow regulating cloth when gas is generated from the inflator, wherein the tubular flow regulating cloth has openings at both ends thereof, and has exhaust holes in a peripheral wall thereof.

公开(公告)号：US20110127755A1

公开(公告)日：2011-06-02

申请号：US13054424

申请日：2009-07-07

申请人： Yoshinori Beppu ,  Hidenori Suzuki ,  Tsubana Nakamura ,  Akihiko Narui

发明人： Yoshinori Beppu ,  Hidenori Suzuki ,  Tsubana Nakamura ,  Akihiko Narui

IPC分类号： B60R21/16

CPC分类号： B60R21/232 ,  B60R21/201 ,  B60R21/233 ,  B60R21/2334 ,  B60R21/237 ,  B60R2021/161

摘要： An object of the present invention is to ensure smooth deployment of an airbag having a turned-back end portion. The present invention is an airbag device that expands and deploys in a curtain shape on a side portion of a vehicle interior in order to protect an occupant of the vehicle interior, where the airbag includes a gas generator for generating an expansion gas and an airbag that deploys when it is expanded by the gas supplied from the gas generator. The airbag is compressed into an elongated shape when stowed and an end portion of the elongated airbag is turned back in a lengthwise direction, thereby forming an airbag main portion that is not turned back and the turned-back end portion. A restricting member is also provided to restrict deployment of the turned-back end portion of the airbag toward a vehicle outer side when the device is activated.

摘要翻译： 本发明的目的是确保具有折回端部的气囊的平滑展开。 本发明是一种气囊装置，其在车辆内部的侧部以窗帘形状展开和展开，以保护车辆内部的乘客，其中，该气囊包括用于产生膨胀气体的气体发生器和气囊， 当通过从气体发生器供应的气体膨胀时展开。 收纳时气囊被压缩成细长形状，并且细长气囊的端部在长度方向上回转，从而形成未折返的气囊主体部分和后端部。 还设置有限制构件，以在装置被启动时限制安全气囊的后端部向车辆外侧的展开。