公开(公告)号：US20120167704A1

公开(公告)日：2012-07-05

申请号：US13261219

申请日：2010-09-29

Applicant: Norbert Lange ,  Norbert Weber

Inventor： Norbert Lange ,  Norbert Weber

IPC: F16H61/00

CPC classification number: F16H61/0021 ,  F15B1/24 ,  F15B21/065 ,  F15B2201/21 ,  F15B2201/31 ,  F15B2201/40 ,  F16H2061/0034 ,  F16H2312/14 ,  Y02E60/15 ,  Y10T74/20024

Abstract: 1. Device for the pulsed release of an amount of fluid (3) which can be stored in an accumulator housing (2). 2. A device for the pulsed release of an amount of fluid which can be stored in a storage housing (2) is characterized in that a locking device (7) is formed by a piston-cylinder arrangement (8) having a cylinder housing (9) that is subdivided into a first working chamber (11) and a second working chamber (12) by a working piston (10), an electrorheological or magnetorheological valve (14) in the form of a gap (15) or an opening being arranged between the working chambers (11, 12) in the circumference (13) of the working piston (10) or in the working piston (10) as such.

Abstract translation: 用于脉冲释放可存储在蓄能器壳体（2）中的一定量流体（3）的装置。 2.一种用于脉冲释放可存储在存储壳体（2）中的流体量的装置，其特征在于，锁定装置（7）由具有气缸壳体（8）的活塞 - 气缸装置（8）形成， 9），其通过工作活塞（10）被分为第一工作室（11）和第二工作室（12），间隙（15）或开口形式的电流变或磁流变阀（14） 布置在工作活塞（10）的周边（13）中或工作活塞（10）中的工作室（11,12）之间。

公开(公告)号：US09038528B2

公开(公告)日：2015-05-26

申请号：US12654994

申请日：2010-01-12

Applicant: Norbert Weber ,  Norbert Lange

Inventor： Norbert Weber ,  Norbert Lange

IPC: F15B15/26 ,  F15B1/04

CPC classification number: F15B1/04 ,  F15B2201/21 ,  F15B2201/31 ,  F15B2201/40 ,  Y02E60/15

Abstract: A device for the pulsed release of an amount (3) of fluid that is stored in a storage housing (2) includes a piston (5) biased by a first spring (4) and movable within the storage housing (2) to dispense the fluid by the spring bias, when triggered by an actuator (6) to release a lock holding the piston in place (7). The lock (7) has individual catches (8) keeping the piston (5) in its pretensioned position and, when actuated by the actuator (6), releases the piston (5).

Abstract translation: 用于脉冲释放存储在存储壳体（2）中的流体量（3）的装置包括由第一弹簧（4）偏置并可在存储壳体（2）内移动的活塞（5），以分配 当由致动器（6）触发以释放将活塞固定就位（7）时的弹簧偏压的流体。 锁（7）具有保持活塞（5）处于其预紧位置的单独的卡扣（8），并且当由致动器（6）致动时，释放活塞（5）。

公开(公告)号：US09046170B2

公开(公告)日：2015-06-02

申请号：US13261219

申请日：2010-09-29

Applicant: Norbert Lange ,  Norbert Weber

Inventor： Norbert Lange ,  Norbert Weber

IPC: F15B1/24 ,  F16H61/00 ,  F15B21/06

CPC classification number: F16H61/0021 ,  F15B1/24 ,  F15B21/065 ,  F15B2201/21 ,  F15B2201/31 ,  F15B2201/40 ,  F16H2061/0034 ,  F16H2312/14 ,  Y02E60/15 ,  Y10T74/20024

Abstract: A device for the pulsed release of an amount of fluid stored in a storage housing (2) has a locking device (7) formed by a piston-cylinder arrangement (8). The arrangement has a cylinder housing (9) subdivided into a first working chamber (11) and a second working chamber (12) by a working piston (10). An electrorheological or magnetorheological valve (14) in the form of a gap (15) or an opening is arranged between the working chambers (11, 12) in the circumference (13) of the working piston (10) or in the working piston (10).

Abstract translation: 用于脉冲释放存储在存储壳体（2）中的流体量的装置具有由活塞 - 气缸装置（8）形成的锁定装置（7）。 该装置具有通过工作活塞（10）细分成第一工作室（11）和第二工作室（12）的缸体壳体（9）。 在工作活塞（10）的圆周（13）或工作活塞（10）中的工作室（11,12）之间布置有间隙（15）或开口形式的电流变或磁流变阀（14） 10）。

公开(公告)号：US20110088548A1

公开(公告)日：2011-04-21

申请号：US12654994

申请日：2010-01-12

Applicant: Norbert Weber ,  Norbert Lange

Inventor： Norbert Weber ,  Norbert Lange

IPC: F15B15/26

CPC classification number: F15B1/04 ,  F15B2201/21 ,  F15B2201/31 ,  F15B2201/40 ,  Y02E60/15

Abstract: A device for the pulsed release of an amount (3) of fluid that is stored in a storage housing (2), in particular for implementing a start-stop function in automatic transmissions, with a piston (5) that is supported against a first energy storage device (4) and that, with the capacity to move within the storage housing (2), limits in conjunction with the latter the amount (3) of fluid that can be held and that, when triggered by an actuation means (6) and released by a locking means (7), pushes the amount (3) of fluid out of the storage housing (2) in a pulsed manner, the locking means (7) having individual catch means (8) that in the locked position keep the piston (5) in its pretensioned position, and that, when actuated by the actuation means (6), release the piston (5) in a release position, is characterized in that in any travel position of the piston (5), the catch means (8) are at least partially in contact with the inside wall of the piston (5) facing them, and that for locking of the piston (5), the catch means (8) act in that end region (9) of the piston (5) that is located adjacent to the stored amount (3) of fluid.

Abstract translation: 用于脉冲释放存储在存储壳体（2）中的流体量（3）的装置，特别是用于在自动变速器中实现起停功能的装置，活塞（5）被支撑在第一 能量存储装置（4），并且具有在存储壳体（2）内移动的能力的情况下，与后者相关联地限制可以保持的流体的量（3），并且当由致动装置（6 ）并通过锁定装置（7）释放，以脉冲的方式将流体的量（3）推出储存壳体（2），锁定装置（7）具有分别锁定装置（8），其处于锁定位置 将活塞（5）保持在其预张紧位置，并且当由致动装置（6）致动时，将活塞（5）释放在释放位置，其特征在于，在活塞（5）的任何行进位置， 捕捉装置（8）至少部分地与面向它们的活塞（5）的内壁和用于锁定的内壁相接触 活塞（5）的止动装置（8）作用在活塞（5）的位于与储存的（3）流体相邻的位置的端部区域（9）中。

公开(公告)号：US07279656B2

公开(公告)日：2007-10-09

申请号：US10993366

申请日：2004-11-22

Applicant: Ralf Grassmel ,  Norbert Lange

Inventor： Ralf Grassmel ,  Norbert Lange

IPC: B23K26/38 ,  A24C1/38

CPC classification number: B23K26/0676 ,  A24C5/606 ,  B23K26/0604 ,  B23K26/0821 ,  B23K26/0823 ,  B23K26/382 ,  B23K2103/40 ,  B23K2103/50

Abstract: The invention relates to a method of and to an apparatus for perforating the tubular wrappers of plain or filter cigarettes and other rod-shaped articles of the tobacco processing industry. The articles are advanced sideways at the periphery of a rotary drum-shaped carrier which cooperates with a device serving to roll them about their longitudinal axes while the wrappers are being perforated by one or more pulsating beams issuing from one or more lasers and passing through a stationary cylinder lens on their way to the facets of a rotating cylindrical mirror which directs the beam(s) across the axis of the carrier and pivots the beam(s) about such axis on its or their way radially outwardly of the carrier toward a first set of stationary deflecting mirrors. These mirrors deflect the beam(s) in at least substantial parallelism with the axis of the carrier at locations radially outwardly of the latter's periphery toward a second set of deflecting mirrors which, in turn, direct the beam(s) substantially radially toward the axis of the carrier and against spherical lenses which focus the beam(s) upon the wrappers of the articles.

Abstract translation: 本发明涉及一种用于穿孔烟草加工业的普通或过滤嘴香烟和其他棒状物品的管状包装纸的方法和装置。 制品在旋转鼓形载体的周边处侧向推进，该装置与用于在其纵向轴线上滚动的装置配合，同时包装纸由一个或多个从一个或多个激光器发出的脉冲波束穿过并穿过一个 固定圆柱透镜在其通向旋转圆柱形反射镜的方向的方向上，其引导束穿过载体的轴线并使梁围绕该轴线在载体的径向向外朝着第一 固定偏转镜组。 这些反射镜使光束在载体的轴线处至少基本平行的方向上偏转到第二组偏转反射镜，第二组偏转反射镜将射束基本径向地朝着轴线 的载体和对准将光束聚焦在物品的包装纸上的球面透镜。

公开(公告)号：US6148227A

公开(公告)日：2000-11-14

申请号：US98286

申请日：1998-06-16

Applicant: Georges Wagnieres ,  Matthieu Zellweger ,  Nicolas Chauvin ,  Norbert Lange ,  Ulf Zanger ,  Andre Studzinski ,  Hubert van den Bergh

Inventor： Georges Wagnieres ,  Matthieu Zellweger ,  Nicolas Chauvin ,  Norbert Lange ,  Ulf Zanger ,  Andre Studzinski ,  Hubert van den Bergh

IPC: H04N5/225 ,  A61B5/00 ,  G01J3/443 ,  G01N21/64 ,  G02B23/24 ,  H04N7/18 ,  H04N9/09

CPC classification number: A61B5/0084 ,  A61B1/043 ,  A61B5/0071 ,  G02B23/2484 ,  H04N7/18

Abstract: The diagnosis apparatus according to the invention for the picture providing recording of fluorescing biological tissue by way of an endoscope contains a stimulation light source which beams spectral components suitable for fluorescence stimulation into the tissue through the endoscope. The fluorescent light reflected by the tissue reaches through the endoscope optics into a head piece where it is split into a green, and spacially separated from this, a red spectral component and falls each on one half of a CCD solid body of a highly sensitive black and white camera. In an electronic and processor component the video signals allocated to the green and to the red spectral component are processed into two separate processing channels in a manner such that the separately processed green-red video signals are simultaneously inputted to a color video monitor and here may be superimposed to a red-green monitor picture, which may show changes of tissue indicating disease, for example dysplasia, carcinomas in situ etc., in all organs which are endoscopically accessible.

Abstract translation: 根据本发明的用于通过内窥镜提供荧光生物组织记录的图像的诊断装置包括将通过内窥镜将适合于荧光刺激的光谱成分射入组织的刺激光源。 由组织反射的荧光通过内窥镜光学器件进入头部，在其中分割成绿色，并与之空间分开，红色光谱分量，并分别落在高灵敏度黑色的CCD固体的一半上 和白色相机。 在电子和处理器部件中，分配给绿色和红色光谱分量的视频信号被处理成两个单独的处理通道，使得分开处理的绿色 - 红色视频信号被同时输入到彩色视频监视器，并且这里可以 叠加到红绿色监视器图像上，其可以显示在内窥镜可访问的所有器官中指示疾病的组织的变化，例如发育不良，原位癌等。

公开(公告)号：US20130178787A1

公开(公告)日：2013-07-11

申请号：US13809093

申请日：2011-07-08

Applicant: Bjorn Klem ,  Norbert Lange

Inventor： Bjorn Klem ,  Norbert Lange

IPC: A61K31/197 ,  A61N5/06

CPC classification number: A61K31/197 ,  A61K9/19 ,  A61K9/7007 ,  A61K41/0061 ,  A61K49/0017 ,  A61K49/0036 ,  A61N5/0601 ,  A61N5/062

Abstract: This invention relates to dry pharmaceutical compositions comprising an active ingredient which is 5-aminolevulinic acid (5-ALA) or a precursor or derivative of 5-ALA, or a pharmaceutically acceptable salt thereof. The compositions may be used in the photodynamic treatment (PDT) or photodynamic diagnosis (PDD) of cancer, pre-cancerous conditions and non-cancerous conditions. The invention relates further to irradiation devices comprising dry compositions and the use of such devices in the photodynamic treatment (PDT) or photodynamic diagnosis (PDD) of cancer, pre-cancerous conditions and non-cancerous conditions.

Abstract translation: 本发明涉及包含5-氨基乙酰丙酸（5-ALA）或5-ALA的前体或衍生物的活性成分或其药学上可接受的盐的干燥药物组合物。 组合物可用于癌症，癌前病症和非癌症病症的光动力学治疗（PDT）或光动力学诊断（PDD）。 本发明进一步涉及包含干组合物的照射装置以及在光动力学治疗（PDT）或癌症，癌前病症和非癌症病症的光动力学诊断（PDD）中使用这些装置。

公开(公告)号：US07348361B2

公开(公告)日：2008-03-25

申请号：US09673871

申请日：1999-04-22

Applicant: Alexandre Marti ,  Norbert Lange ,  Matthieu Zellweger ,  Georges Wagnieres ,  Hubert Van Den Bergh ,  Patrice Jichlinski ,  Pavel Kucera

Inventor： Alexandre Marti ,  Norbert Lange ,  Matthieu Zellweger ,  Georges Wagnieres ,  Hubert Van Den Bergh ,  Patrice Jichlinski ,  Pavel Kucera

IPC: A61K31/195 ,  A61K49/00 ,  A61K31/40 ,  A01N43/38

CPC classification number: A61K31/22

Abstract: The invention concerns a 5-aminolevulinic acid ester (E-ALA) solution for producing a pharmaceutical preparation useful for diagnosing and/or treating tissue and/or cell pathologies by local radiation exposure using radiation emitted by a light source energy followed, in the case diagnosis, by detection of fluorescent protoporphyrin IX (Pp1X). The E-ALA concentration in the solution is less than 1% and ranges between 0.01% and 0.5%. The low E-ALA concentration in the solution increases Pp1X synthesis and homogenises its distribution in the cell layers while highly reducing the secondary toxicity for the treated cells.

Abstract translation: 本发明涉及用于生产药物制剂的5-氨基乙酰丙酸酯（E-ALA）溶液，其用于通过使用由光源能量发射的辐射的局部辐射暴露来诊断和/或治疗组织和/或细胞病理学，在这种情况下 通过检测荧光原卟啉IX（Pp1X）进行诊断。 溶液中的E-ALA浓度小于1％，范围在0.01％至0.5％之间。 溶液中的低E-ALA浓度增加Pp1X合成并使其在细胞层中的分布均匀化，同时高度降低处理细胞的次生毒性。

公开(公告)号：US20070246053A1

公开(公告)日：2007-10-25

申请号：US11725565

申请日：2007-03-20

Applicant: Ralf Grassmel ,  Norbert Lange

Inventor： Ralf Grassmel ,  Norbert Lange

IPC: A24C5/00

CPC classification number: A24C5/606 ,  B23K26/0608 ,  B23K26/067 ,  B23K26/382 ,  B23K2103/32 ,  B23K2103/40 ,  B23K2103/50

Abstract: A perforation apparatus of the tobacco-processing industry for perforating a wrapper of a rod-shaped article includes at least one optical radiation source to generate at least one primary beam. Optical elements are operative to split the at least one primary beam into at least four mutually non-overlapping partial beams to produce at least four perforation zones offset in an axial direction of the rod-shaped article. Partial beams arranged mirror symmetrically to each other with respect to a mirror plane of the rod-shaped article are derived from the same primary beam.

Abstract translation: 烟草加工工业用于穿孔棒状制品的包装物的穿孔装置包括至少一个光辐射源以产生至少一个主光束。 光学元件可操作以将至少一个主光束分成至少四个相互不重叠的部分光束，以产生沿棒状物体的轴向偏移的至少四个穿孔区域。 相对于棒状物品的镜面彼此对称配置的部分光束来自相同的一次光束。

公开(公告)号：US4889140A

公开(公告)日：1989-12-26

申请号：US510400

申请日：1983-07-01

Applicant: Heinz C. Lorenzen ,  Peter Pinck ,  Norbert Lange

Inventor： Heinz C. Lorenzen ,  Peter Pinck ,  Norbert Lange

IPC: A24C5/00 ,  A24C5/14 ,  A24C5/60 ,  B23K26/00 ,  B23K26/04 ,  B23K26/067 ,  B23K26/08 ,  B23K26/38 ,  B31F7/00 ,  H01S3/08

CPC classification number: B23K26/0676 ,  A24C5/606 ,  B23K26/04 ,  B23K26/067 ,  B23K26/0846

Abstract: Apparatus for making perforations in a running web of wrapping material for tobacco or filter rods or in the wrappers of discrete cigarettes has a carbon dioxide laser with two parallel resonators which are mechanically coupled to each other to define a U-shaped resonance chamber and the free ends of which carry partially transmitting mirrors for the passage of discrete active beams of coherent radiation. The two active beams are thereupon split into pairs of split beams and the split beams are focused upon the running web of wrapping material or upon the wrappers of successive rod-shaped articles to simultaneously form four rows of perforations.

Abstract translation: 用于在用于烟草或过滤棒的包装材料的运行卷材或分散香烟的包装纸中的穿孔的设备具有二个具有两个并联谐振器的二氧化碳激光器，它们彼此机械耦合以限定U形共振室， 其端部承载部分透射镜用于相干辐射的离散有源光束的通过。 这两个有源光束随后分成成对的分束，并且分离光束聚焦在包裹材料的运行卷材上或连续的棒状物品的包装纸上，以同时形成四排穿孔。