公开(公告)号：US20170227521A1

公开(公告)日：2017-08-10

申请号：US15015244

申请日：2016-02-04

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01N33/49 ,  G01N21/25 ,  G01N21/03

CPC classification number: G01N33/49 ,  G01J3/0202 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/0297 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/2866 ,  G01N21/0303 ,  G01N21/255 ,  G01N21/274 ,  G01N21/31 ,  G01N33/492 ,  G01N2021/0321 ,  G01N2021/0389 ,  G01N2201/062 ,  G01N2201/0633 ,  G01N2201/0634 ,  G01N2201/0638

Abstract: A system of measuring hemoglobin and bilirubin parameters in a whole blood sample using optical absorbance. The system includes an optical-sample module, a spectrometer module, an optical fiber module optically connecting the optical-sample module to the spectrometer module, and a processor module. The optical-sample module has a light-emitting module having a LED light source, a cuvette and a calibrating-light module. The processor module receives and processes an electrical signal from the spectrometer module and transforms the electrical signal into an output signal useable for displaying and reporting hemoglobin parameter values and/or total bilirubin parameter values for the whole blood sample.

公开(公告)号：US09638686B1

公开(公告)日：2017-05-02

申请号：US15015278

申请日：2016-02-04

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01N33/48 ,  G01N33/49 ,  G01N21/27 ,  G01N33/487

CPC classification number: G01N33/492 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/14 ,  G01J3/42 ,  G01N21/21 ,  G01N21/274 ,  G01N21/31 ,  G01N33/48792 ,  G01N2021/216 ,  G01N2201/0634

Abstract: A method of measuring whole-blood hemoglobin parameters includes providing a LED light source, guiding light having the spectral range from the LED light source along an optical path, providing a cuvette module with a sample receiving chamber, providing a pair of first and second optical diffusers disposed in the optical path where the cuvette module is disposed between the pair of first and second optical diffusers, guiding light from the cuvette module into an optical spectrometer, and processing an electrical signal from the spectrometer into an output signal useable for displaying and reporting hemoglobin parameter values and/or total bilirubin parameter values of the sample of whole blood.

公开(公告)号：US10338058B2

公开(公告)日：2019-07-02

申请号：US16132689

申请日：2018-09-17

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01N21/27 ,  G01J3/02 ,  G01N33/49 ,  G01N21/25 ,  G01N21/31 ,  G01J3/42 ,  G01N21/03 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28

Abstract: A calibrating-light module for use in a system for measuring whole-blood hemoglobin parameters or whole-blood bilirubin parameters. The calibrating-light module includes a calibrating module housing, a light beam receiving portion connected to a first end of the calibrating module housing, a calibrating light portion connected to a side of the calibrating module housing wherein the side is transverse to the first end, and an optic fiber portion connected to a second end of the calibrating module housing wherein the calibrating module housing, the light beam receiving portion and the optic fiber portion are aligned with an optical path and the calibrating light portion is spaced from and transverse to the optical path.

公开(公告)号：US10337980B2

公开(公告)日：2019-07-02

申请号：US16134245

申请日：2018-09-18

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01J3/02 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01J3/42 ,  G01N21/03 ,  G01N21/25 ,  G01N21/27 ,  G01N21/31 ,  G01N33/49

Abstract: A replaceable cuvette assembly for use in an optical absorbance measurement system for measuring whole-blood hemoglobin parameters or whole-blood bilirubin parameters. The replaceable cuvette assembly includes a cuvette substrate and a cuvette module fixedly connected to the cuvette substrate wherein the cuvette substrate is a support for securing the cuvette assembly within the optical absorbance measurement system. The cuvette module has a sample inlet port, a sample outlet port, an electronic chip assembly, a sample receiving chamber that fluidly communicates with the sample inlet port and the sample outlet port, a first cuvette window, and a second cuvette window forming a portion of the sample receiving chamber. The first cuvette window and the second cuvette window are aligned with each other defining a cuvette optical path length between the first cuvette window and the second cuvette window and disposed within an optical path of the optical absorbance measurement system.

公开(公告)号：US10088468B2

公开(公告)日：2018-10-02

申请号：US15015244

申请日：2016-02-04

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01N33/49 ,  G01J3/02 ,  G01J3/42 ,  G01N21/31 ,  G01N21/27 ,  G01N21/03 ,  G01N21/25

Abstract: A system of measuring hemoglobin and bilirubin parameters in a whole blood sample using optical absorbance. The system includes an optical-sample module, a spectrometer module, an optical fiber module optically connecting the optical-sample module to the spectrometer module, and a processor module. The optical-sample module has a light-emitting module having a LED light source, a cuvette and a calibrating-light module. The processor module receives and processes an electrical signal from the spectrometer module and transforms the electrical signal into an output signal useable for displaying and reporting hemoglobin parameter values and/or total bilirubin parameter values for the whole blood sample.

公开(公告)号：US20190033287A1

公开(公告)日：2019-01-31

申请号：US16134245

申请日：2018-09-18

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01N33/49 ,  G01J3/02 ,  G01N21/25 ,  G01N21/03 ,  G01J3/42 ,  G01N21/31 ,  G01N21/27

CPC classification number: G01N21/0303 ,  G01J3/0202 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/0297 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/2866 ,  G01N21/255 ,  G01N21/274 ,  G01N21/31 ,  G01N33/49 ,  G01N33/492 ,  G01N2021/0321 ,  G01N2021/0389 ,  G01N2201/062 ,  G01N2201/0633 ,  G01N2201/0634 ,  G01N2201/0638

Abstract: A replaceable cuvette assembly for use in an optical absorbance measurement system for measuring whole-blood hemoglobin parameters or whole-blood bilirubin parameters. The replaceable cuvette assembly includes a cuvette substrate and a cuvette module fixedly connected to the cuvette substrate wherein the cuvette substrate is a support for securing the cuvette assembly within the optical absorbance measurement system. The cuvette module has a sample inlet port, a sample outlet port, an electronic chip assembly, a sample receiving chamber that fluidly communicates with the sample inlet port and the sample outlet port, a first cuvette window, and a second cuvette window forming a portion of the sample receiving chamber. The first cuvette window and the second cuvette window are aligned with each other defining a cuvette optical path length between the first cuvette window and the second cuvette window and disposed within an optical path of the optical absorbance measurement system.

公开(公告)号：US20190017992A1

公开(公告)日：2019-01-17

申请号：US16132689

申请日：2018-09-17

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01N33/49 ,  G01J3/02 ,  G01N21/25 ,  G01N21/03 ,  G01J3/42 ,  G01N21/31 ,  G01N21/27

CPC classification number: G01N21/0303 ,  G01J3/0202 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/0297 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/2866 ,  G01N21/255 ,  G01N21/274 ,  G01N21/31 ,  G01N33/49 ,  G01N33/492 ,  G01N2021/0321 ,  G01N2021/0389 ,  G01N2201/062 ,  G01N2201/0633 ,  G01N2201/0634 ,  G01N2201/0638

Abstract: A calibrating-light module for use in a system for measuring whole-blood hemoglobin parameters or whole-blood bilirubin parameters. The calibrating-light module includes a calibrating module housing, a light beam receiving portion connected to a first end of the calibrating module housing, a calibrating light portion connected to a side of the calibrating module housing wherein the side is transverse to the first end, and an optic fiber portion connected to a second end of the calibrating module housing wherein the calibrating module housing, the light beam receiving portion and the optic fiber portion are aligned with an optical path and the calibrating light portion is spaced from and transverse to the optical path.

公开(公告)号：US20190017991A1

公开(公告)日：2019-01-17

申请号：US16132554

申请日：2018-09-17

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01N33/49 ,  G01J3/02 ,  G01N21/25 ,  G01N21/03 ,  G01J3/42 ,  G01N21/31 ,  G01N21/27

Abstract: A light-emitting module for use in a system for measuring whole-blood hemoglobin parameters or whole-blood bilirubin parameters. The light-emitting module includes an LED light source capable of emitting light wherein the light is directed thereby defining an optical path and a plurality of optical components. The plurality of optical components includes a collimating lens, a first optical diffuser, a circular polarizer, and a focusing lens wherein the plurality of optical components is disposed within the optical path of the light from the LED light source

公开(公告)号：US10151630B2

公开(公告)日：2018-12-11

申请号：US15015251

申请日：2016-02-04

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01J3/02 ,  G01J3/42 ,  G01N21/27 ,  G01J3/14 ,  G01N33/49 ,  G01J3/10 ,  G01J3/28 ,  G01N21/31

Abstract: An optical spectrometer for use in a COOx analyzer includes a spectrometer housing having an optical fiber housing end, a light-receiving input slit positioned adjacent the optical fiber housing end, a light dispersing element mounted to but spaced from the optical fiber housing end and positioned within an optical path along which light travels from the light-receiving input slit. The light dispersing element receives the light transmitted through the input slit and separates the light into a plurality of light beams, a light-array detector capable of receiving the plurality of light beams and converting the plurality of light beams into the electrical signal, an achromatic lens positioned in the optical path to direct the light from the input slit to the light dispersing element and to direct the plurality of light beams reflected from the light dispersing element onto the light-array detector, and a thermal-compensating means for the spectrometer housing.

公开(公告)号：US10345146B2

公开(公告)日：2019-07-09

申请号：US16133002

申请日：2018-09-17

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01J3/02 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01J3/42 ,  G01N21/03 ,  G01N21/25 ,  G01N21/27 ,  G01N21/31 ,  G01N33/49

Abstract: An optical component group for use in a spectrometer module of a system for measuring whole-blood hemoglobin parameters or whole-blood bilirubin parameters. The optical component group includes a light dispersing element and an achromatic lens assembly disposed between the light dispersing element and a light entrance port of the spectrometer module where the achromatic lens assembly is thermo-compensating permitting thermal expansion and contraction of the achromatic lens assembly in a linear direction where the linear directions is also transverse to a light beam from the light entrance port through the achromatic lens assembly and to the light dispersing element and back through the achromatic lens assembly.