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公开(公告)号：US20140255550A1
公开(公告)日：2014-09-11
申请号：US14286089
申请日：2014-05-23
申请人： Novozymes A/S
发明人： Leonardo De Maria , Carsten Andersen , Lars Lehmann Hyllling Christensen , Soren Flensted Lassen , Peter Rahbek Ostergaard
CPC分类号： C12N9/58 , A01K2217/05 , A23K20/189 , C12N9/48 , C12N9/52 , C12N2310/111
摘要： The invention relates to a novel 3D structure encoding a Nocardiopsis protease, as well as to variants of parent protease homologous to Nocardiopsis proteases, preferably of improved thermostability and/or with an amended temperature activity profile. The invention also relates to DNA sequences encoding such variants, their production in a recombinant host cell, as well as methods of using the variants, in particular within the field of animal feed and detergents. The invention furthermore relates to methods of generating and preparing protease variants of amended properties.
摘要翻译： 本发明涉及编码诺卡氏菌蛋白酶的新型3D结构，以及与诺卡氏菌蛋白酶同源的亲本蛋白酶的变体，优选具有改善的热稳定性和/或具有修改的温度活性分布。 本发明还涉及编码这些变体的DNA序列，其在重组宿主细胞中的产生，以及使用该变体，特别是在动物饲料和洗涤剂领域中的方法。 本发明还涉及生成和制备修饰性质的蛋白酶变体的方法。
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公开(公告)号：US09428742B2
公开(公告)日：2016-08-30
申请号：US13959577
申请日：2013-08-05
申请人： Novozymes A/S , Novozymes, Inc.
CPC分类号： C12N9/2434 , C12N9/2437 , C12Y302/01004
摘要： The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
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公开(公告)号：US20130330781A1
公开(公告)日：2013-12-12
申请号：US13683165
申请日：2012-11-21
申请人： Novozymes A/S
发明人： Martin Schulein , Lene Nonboe Andersen , Soren Flensted Lassen , Markus Sakari Kauppinen , Lene Lange , Ruby Ilum Nielsen , Shinobu Takagi , Michiko Ihara
CPC分类号： C12N9/2437 , A61K38/00 , C05F11/08 , C05F17/0036 , C07K2319/00 , C11D3/386 , C12P19/14 , C12Y302/01004 , D06M16/003 , D06P5/02 , D06P5/158 , D21C5/005 , D21H17/005 , D21H21/10 , Y02P20/145 , Y02W30/43
摘要： The present invention relates to enzyme preparations consisting essentially of an enzyme which has cellulytic activity, which perform very well in industrial applications such as laundry compositions, for biopolishing of newly manufactured textiles, for providing an abraded look of cellulosic fabric or garment, and for treatment of paper pulp. Further, the invention relates to DNA constructs encoding such enzymes, a method for providing a gene encoding for such enzymes, a method of producing the enzymes, enzyme preparations containing such enzymes, and the use of these enzymes for a number of industrial applications.
摘要翻译： 本发明涉及酶制剂，其基本上由具有纤维素分解活性的酶组成，其在诸如洗衣组合物的工业应用中表现非常好，用于生产抛光新制造的纺织品，用于提供纤维素织物或服装的磨损外观，以及用于治疗 的纸浆。 此外，本发明涉及编码这些酶的DNA构建体，提供编码这种酶的基因的方法，生产酶的方法，含有这些酶的酶制剂，以及这些酶用于许多工业应用的用途。
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公开(公告)号：US20160138000A1
公开(公告)日：2016-05-19
申请号：US15002816
申请日：2016-01-21
申请人： Novozymes A/S
IPC分类号： C12N9/52
CPC分类号： C12N9/52 , A23J3/346 , A23K20/189 , A23K50/30 , A23K50/60 , A23K50/75 , C11D3/38609 , C11D3/38618
摘要： Proteases derived from Nocardiopsis dassonvillei subsp. dassonvillei DSM 43235, Nocardiopsis prasina DSM 15649, Nocardiopsis prasina (previously alba) DSM 14010 Nocardiopsis sp. DSM 16424, Nocardiopsis alkaliphila DSM 44657 and Nocardiopsis lucentensis DSM 44048, as well as homologous proteases; their recombinant production in various hosts, including transgenic plants and non-human animals, and their use in animal feed and detergents. The proteases are acid-stable, alkali-stable, and/or thermostable.
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公开(公告)号：US09131711B2
公开(公告)日：2015-09-15
申请号：US14286089
申请日：2014-05-23
申请人： Novozymes A/S
发明人： Leonardo De Maria , Carsten Andersen , Lars Lehmann Hyllling Christensen , Soren Flensted Lassen , Peter Rahbek Ostergaard
CPC分类号： C12N9/58 , A01K2217/05 , A23K20/189 , C12N9/48 , C12N9/52 , C12N2310/111
摘要： The invention relates to a novel 3D structure encoding a Nocardiopsis protease, as well as to variants of parent protease homologous to Nocardiopsis proteases, preferably of improved thermostability and/or with an amended temperature activity profile. The invention also relates to DNA sequences encoding such variants, their production in a recombinant host cell, as well as methods of using the variants, in particular within the field of animal feed and detergents. The invention furthermore relates to methods of generating and preparing protease variants of amended properties.
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公开(公告)号：US09023620B2
公开(公告)日：2015-05-05
申请号：US13683165
申请日：2012-11-21
申请人： Novozymes A/S
发明人： Martin Schulein , Lene Nonboe Andersen , Soren Flensted Lassen , Markus Sakari Kauppinen , Lene Lange , Ruby Ilum Nielsen , Shinobu Takagi , Michiko Ihara
IPC分类号： A61K38/00 , C12N9/42 , C05F11/08 , C05F17/00 , C11D3/386 , D06M16/00 , D06P5/02 , D06P5/15 , D21C5/00 , D21H21/10 , C12P19/14 , D21H17/00
CPC分类号： C12N9/2437 , A61K38/00 , C05F11/08 , C05F17/0036 , C07K2319/00 , C11D3/386 , C12P19/14 , C12Y302/01004 , D06M16/003 , D06P5/02 , D06P5/158 , D21C5/005 , D21H17/005 , D21H21/10 , Y02P20/145 , Y02W30/43
摘要： The present invention relates to enzyme preparations consisting essentially of an enzyme which has cellulytic activity, which perform very well in industrial applications such as laundry compositions, for biopolishing of newly manufactured textiles, for providing an abraded look of cellulosic fabric or garment, and for treatment of paper pulp. Further, the invention relates to DNA constructs encoding such enzymes, a method for providing a gene encoding for such enzymes, a method of producing the enzymes, enzyme preparations containing such enzymes, and the use of these enzymes for a number of industrial applications.
摘要翻译： 本发明涉及酶制剂，其基本上由具有纤维素分解活性的酶组成，其在诸如洗衣组合物的工业应用中表现非常好，用于生产抛光新制造的纺织品，用于提供纤维素织物或服装的磨损外观，以及用于治疗 的纸浆。 此外，本发明涉及编码这些酶的DNA构建体，提供编码这种酶的基因的方法，生产酶的方法，含有这些酶的酶制剂，以及这些酶用于许多工业应用的用途。
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公开(公告)号：US08772011B2
公开(公告)日：2014-07-08
申请号：US13738490
申请日：2013-01-10
申请人： Novozymes A/S
发明人： Leonardo De Maria , Carsten Andersen , Lars Lehmann Hylling Christensen , Soren Flensted Lassen , Peter Rahbek Ostergaard
CPC分类号： C12N9/58 , A01K2217/05 , A23K20/189 , C12N9/48 , C12N9/52 , C12N2310/111
摘要： The invention relates to a novel 3D structure encoding a Nocardiopsis protease, as well as to variants of parent protease homologous to Nocardiopsis proteases, preferably of improved thermostability and/or with an amended temperature activity profile. The invention also relates to DNA sequences encoding such variants, their production in a recombinant host cell, as well as methods of using the variants, in particular within the field of animal feed and detergents. The invention furthermore relates to methods of generating and preparing protease variants of amended properties.
摘要翻译： 本发明涉及编码诺卡氏菌蛋白酶的新型3D结构，以及与诺卡氏菌蛋白酶同源的亲本蛋白酶的变体，优选具有改善的热稳定性和/或具有修改的温度活性分布。 本发明还涉及编码这些变体的DNA序列，其在重组宿主细胞中的产生，以及使用该变体，特别是在动物饲料和洗涤剂领域中的方法。 本发明还涉及生成和制备修饰性质的蛋白酶变体的方法。
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公开(公告)号：US20130189732A1
公开(公告)日：2013-07-25
申请号：US13738490
申请日：2013-01-10
申请人： Novozymes A/S
发明人： Leonardo De Maria , Carsten Andersen , Lars Lehmann Hylling Christensen , Soren Flensted Lassen , Peter Rahbek Ostergaard
CPC分类号： C12N9/58 , A01K2217/05 , A23K20/189 , C12N9/48 , C12N9/52 , C12N2310/111
摘要： The invention relates to a novel 3D structure encoding a Nocardiopsis protease, as well as to variants of parent protease homologous to Nocardiopsis proteases, preferably of improved thermostability and/or with an amended temperature activity profile. The invention also relates to DNA sequences encoding such variants, their production in a recombinant host cell, as well as methods of using the variants, in particular within the field of animal feed and detergents. The invention furthermore relates to methods of generating and preparing protease variants of amended properties.
摘要翻译： 本发明涉及编码诺卡氏菌蛋白酶的新型3D结构，以及与诺卡氏菌蛋白酶同源的亲本蛋白酶的变体，优选具有改善的热稳定性和/或具有修改的温度活性分布。 本发明还涉及编码这些变体的DNA序列，其在重组宿主细胞中的产生，以及使用该变体，特别是在动物饲料和洗涤剂领域中的方法。 本发明还涉及生成和制备修饰性质的蛋白酶变体的方法。
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