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公开(公告)号：US11188736B2
公开(公告)日：2021-11-30
申请号：US17025372
申请日：2020-09-18
Applicant: OLYMPUS CORPORATION
Inventor： Masahito Dohi
Abstract: An observation device includes: an illumination unit that generates illumination light to be radiated onto cells floating in a culture fluid inside a culture vessel; a light receiving unit that receives observation light coming from the cells that have been irradiated with the illumination light, the observation light being imaged by an image-forming optical system; and a casing that has a transmissive section so as to transmit the illumination light and the observation light and that accommodates the illumination unit and the light receiving unit, wherein the casing has an elongated cylindrical form that is configured to be inserted into the culture fluid via a port used to insert a tube into the culture vessel.
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公开(公告)号：US09915814B2
公开(公告)日：2018-03-13
申请号：US15060585
申请日：2016-03-03
Applicant: OLYMPUS CORPORATION
Inventor： Makio Ueno , Masahito Dohi , Atsuhiro Tsuchiya , Hiroyasu Hebiishi
CPC classification number: G02B21/0076 , A61B5/0059 , A61B5/0062 , G01N21/6402 , G01N21/6458 , G01N21/6486 , G02B21/0032 , G02B21/0084 , G02B21/361 , G02B27/0025 , G02B27/141
Abstract: A fluorescence observation unit includes a scanner that scans ultrashort pulsed laser light, a pupil projection lens that focuses the scanned ultrashort pulsed laser light, an image-forming lens that converts the focused ultrashort pulsed laser light to substantially collimated light and causes the ultrashort pulsed laser light to be incident on the objective lens, and a dichroic mirror that splits off, from the optic path of the ultrashort pulsed laser light, fluorescence generated in a sample due to irradiation with the ultrashort pulsed laser light and collected by the objective lens. The image-forming lens includes a first optical system having positive refractive power, and a second optical system having negative refractive power and disposed at a position closer to the scanner than the first optical system is. The dichroic mirror is disposed between the first optical system and the second optical system.
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公开(公告)号：US09625694B2
公开(公告)日：2017-04-18
申请号：US15155965
申请日：2016-05-16
Applicant: OLYMPUS CORPORATION
Inventor： Masahito Dohi
CPC classification number: G02B21/0048 , G02B5/3083 , G02B21/002 , G02B21/0032 , G02B21/0076 , G02B26/101 , G02B26/105 , G02B27/283
Abstract: For achieving an expanded observation range without sacrificing resolution, a scanning optical system according to the present invention includes a scanner that deflects laser light from a light source while changing a deflection angle of the laser light; a polarization beam splitter that is capable of splitting-off the laser light from an optical path of the laser light deflected by the scanner; a polarization beam splitter that is disposed between the light source and the scanner and that causes the laser light split-off by the polarization beam splitter to travel toward the scanner; and a first relay optical system that has 1× relay magnifying power and that is disposed between the polarization beam splitter and the polarization beam splitter. The first relay optical system relays the laser light split-off by the polarization beam splitter so as to cause the laser light to be incident again on the scanner at the same position as an incident position of the laser light from the light source via the polarization beam splitter.
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4.发明授权公开(公告)号：US11314075B2
公开(公告)日：2022-04-26
申请号：US16988828
申请日：2020-08-10
Applicant: OLYMPUS CORPORATION
Inventor： Masahito Dohi , Motohiro Shibata
Abstract: An image processing device is configured to: generate a histogram of pixel values of a plurality of pixels contained in an image; set a background pixel value by using a peak value of the generated histogram; set a noise range with respect to the set background pixel value; and replace the pixel values that fall in the set noise range with a single arbitrary pixel value.
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公开(公告)号：US10788657B2
公开(公告)日：2020-09-29
申请号：US15983265
申请日：2018-05-18
Applicant: OLYMPUS CORPORATION
Inventor： Kenji Kawasaki , Masahito Dohi
Abstract: A microscope illumination device includes a white LED light source and an illumination optical system. The white LED light source includes a substrate, a plurality of LED chips, and a fluorescent substance layer provided to cover the plurality of LED chips, the plurality of LED chips being arrayed on the substrate and being configured to emit excitation light. The illumination optical system includes a field stop and a light diffusion element that is arranged between the white LED light source and the field stop. The microscope illumination device satisfies 0.2
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Patent Agency Ranking
公开(公告)号：US10859803B2
公开(公告)日：2020-12-08
申请号：US15868615
申请日：2018-01-11
Applicant: OLYMPUS CORPORATION
Inventor： Masahito Dohi
Abstract: An illumination device includes: an objective; a first scanning device that moves a focusing position of light in an optical-axis direction of the objective; and a relay optical system that is configured to correct an aberration that is generated in the objective by the first scanning device moving the focusing position, the relay optical system being arranged on an optical path between the first scanning device and the objective.
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公开(公告)号：US09690085B2
公开(公告)日：2017-06-27
申请号：US14607877
申请日：2015-01-28
Applicant: OLYMPUS CORPORATION
Inventor： Masahito Dohi
CPC classification number: G02B21/06 , G02B21/26 , G02B21/33 , G02B21/361 , G02B26/0808
Abstract: A microscope illumination apparatus includes an optical conversion unit that converts laser light incident thereon from a light source to laser light that has an NA and whose main optical axis is distributed on a conical surface that widens at a predetermined angle with respect to an incident optical axis of the laser light, and from which the laser light exits, and an optical device that has no refractive power and that deflects the laser light, which has exited the optical conversion unit, in a direction parallel to the incident optical axis, wherein the microscope illumination apparatus focuses laser light that has exited the optical device at a pupil position of a focusing lens for illuminating a specimen or a position that is conjugate with the position.
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公开(公告)号：US09268150B2
公开(公告)日：2016-02-23
申请号：US13896217
申请日：2013-05-16
Applicant: OLYMPUS CORPORATION
Inventor： Masahito Dohi
CPC classification number: G02B27/30 , F21V5/04 , G02B21/0032 , G02B21/0076 , G02B21/06 , G02B21/16 , G02B21/26
Abstract: A collimator lens is configured with a double convex single lens formed with a resinous material, for collimating a light flux emitted from a light source. At least one of surfaces of the collimator lens is formed as an aspherical surface. The collimator lens satisfies following conditions: 2 0.6, where R1 is a curvature radius of a first surface, which is a lens surface on a side of the light source of the collimator lens, R2 is a curvature radius of a second surface, which is a lens surface on a side opposite to the first surface of the collimator lens, and NA is a numerical aperture on the side of the light source of the collimator lens.
Abstract translation: 准直透镜配置有由树脂材料形成的双凸单透镜，用于准直从光源发射的光束。 准直透镜的至少一个表面形成为非球面。 准直透镜满足以下条件：2 <| R1 / R2 | <10; NA> 0.6，其中R1是作为准直透镜的光源一侧的透镜面的第一面的曲率半径，R2是作为侧面的透镜面的第二面的曲率半径 与准直透镜的第一表面相对，NA是准直透镜的光源侧的数值孔径。
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公开(公告)号：US11150457B2
公开(公告)日：2021-10-19
申请号：US16803063
申请日：2020-02-27
Applicant: OLYMPUS CORPORATION
Inventor： Masahito Dohi
Abstract: An observation device includes an objective lens disposed below a container to collect light from a specimen; a surface light source that is disposed at a pupil position of the objective lens in the optical path of the illumination light, that causes illumination light to enter the container from below, and that can change a light emission pattern in a direction intersecting an emission optical axis, an imaging optical system that captures light from the specimen generated by the specimen being irradiated with the illumination light from the surface light source and focused by the objective lens below the container; and a controller that corrects a light emission pattern on a basis of the light emission pattern and at least one of a brightness, contrast, and the relationship between the number of pixels and the luminance of an acquired image with the light emission pattern.
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公开(公告)号：US10890743B2
公开(公告)日：2021-01-12
申请号：US15868615
申请日：2018-01-11
Applicant: OLYMPUS CORPORATION
Inventor： Masahito Dohi
Abstract: An illumination device includes: an objective; a first scanning device that moves a focusing position of light in an optical-axis direction of the objective; and a relay optical system that is configured to correct an aberration that is generated in the objective by the first scanning device moving the focusing position, the relay optical system being arranged on an optical path between the first scanning device and the objective.
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