公开(公告)号：US09817222B2

公开(公告)日：2017-11-14

申请号：US14874009

申请日：2015-10-02

Applicant: OLYMPUS CORPORATION

Inventor： Shingo Suzuki ,  Takuma Kimura ,  Makio Ueno

IPC: G02B21/06 ,  G02B21/24 ,  G02B26/08 ,  G02B27/14

CPC classification number: G02B21/06 ,  G02B21/24 ,  G02B26/0816 ,  G02B27/144 ,  G02B27/145

Abstract: A microscope system includes a laser light source, a plurality of laser microscopes, and an optical path switching unit that is provided between the laser light source and the laser microscopes and switches a supply destination of a laser beam among the plurality of laser microscopes by changing a beam splitter to be arranged on an incident optical axis. Each of the laser microscopes includes an optical axis adjustment unit that adjusts an optical axis of the laser beam, and a control unit that controls the optical axis adjustment unit based on identification information about the beam splitter arranged on the incident optical axis.

公开(公告)号：US09823456B2

公开(公告)日：2017-11-21

申请号：US15098092

申请日：2016-04-13

Applicant: OLYMPUS CORPORATION

Inventor： Kanako Kondo ,  Makio Ueno

IPC: G02B26/08 ,  G02B21/00 ,  G02B21/08 ,  G02B26/10

CPC classification number: G02B21/0048 ,  G02B21/0032 ,  G02B21/0076 ,  G02B21/08 ,  G02B26/101 ,  G02B26/105

Abstract: In order to allow precise observation of a specimen at an observation point with a desired depth without changing the working distance of an objective optical system while employing a simple configuration, a laser scanning microscope according to the present invention includes an objective lens having a plurality of optical elements that are disposed with gaps therebetween in an optical-axis direction and that condense laser light emitted from a light source onto a specimen and also having an adjustment ring that allows changing of the focal point by moving the optical elements in the optical-axis direction; a scanner that has a galvanometer mirror capable of oscillating about a predetermined oscillation axis and that scans the laser light condensed onto the specimen by the objective lens in accordance with an oscillation angle of the galvanometer mirror; a light detecting unit that obtains image information of the specimen on the basis of return light returned from the specimen scanned with the laser light; and a scanner controlling unit that controls the oscillation angle of the galvanometer mirror so as to maintain an observation range of the specimen observed by the light detecting unit on the basis of the positions of the optical elements moved by the adjustment ring.

公开(公告)号：US09915814B2

公开(公告)日：2018-03-13

申请号：US15060585

申请日：2016-03-03

Applicant: OLYMPUS CORPORATION

Inventor： Makio Ueno ,  Masahito Dohi ,  Atsuhiro Tsuchiya ,  Hiroyasu Hebiishi

IPC: G02B21/00 ,  G02B21/36 ,  G02B27/14 ,  G02B27/00 ,  G01N21/64 ,  A61B5/00

CPC classification number: G02B21/0076 ,  A61B5/0059 ,  A61B5/0062 ,  G01N21/6402 ,  G01N21/6458 ,  G01N21/6486 ,  G02B21/0032 ,  G02B21/0084 ,  G02B21/361 ,  G02B27/0025 ,  G02B27/141

Abstract: A fluorescence observation unit includes a scanner that scans ultrashort pulsed laser light, a pupil projection lens that focuses the scanned ultrashort pulsed laser light, an image-forming lens that converts the focused ultrashort pulsed laser light to substantially collimated light and causes the ultrashort pulsed laser light to be incident on the objective lens, and a dichroic mirror that splits off, from the optic path of the ultrashort pulsed laser light, fluorescence generated in a sample due to irradiation with the ultrashort pulsed laser light and collected by the objective lens. The image-forming lens includes a first optical system having positive refractive power, and a second optical system having negative refractive power and disposed at a position closer to the scanner than the first optical system is. The dichroic mirror is disposed between the first optical system and the second optical system.

公开(公告)号：US09261689B2

公开(公告)日：2016-02-16

申请号：US14298707

申请日：2014-06-06

Applicant: OLYMPUS CORPORATION

Inventor： Yoshihiro Shimada ,  Makio Ueno ,  Shingo Tamano ,  Naoki Hayashi ,  Eiji Yokoi

IPC: G02B21/06 ,  G02F1/11 ,  G02B21/26 ,  G02B21/00 ,  G02B27/42

CPC classification number: G02B21/0032 ,  G02B21/002 ,  G02B21/0036 ,  G02B21/0096 ,  G02B21/06 ,  G02B21/26 ,  G02B27/4261

Abstract: A scanning optical microscope includes a light source, a light converging optical system, a stage, a scanning unit which displaces an illumination light and the stage relatively, a detecting optical system, and a photodetector. A light modulation element and a relay optical system are disposed on the light converging optical system side of the light source, and a modulated signal having only amplitude changed is input to the light modulation element, and the light modulation element is positioned such that the illumination light emerged from the light modulation element with respect to the modulated signal of a predetermined amplitude coincides with an optical axis of the light converging optical system, and a position of a pupil of the light converging optical system and a position of the light modulation element are conjugate through at least the relay optical system.

Abstract translation: 扫描光学显微镜包括光源，聚光光学系统，舞台，相对地移动照明光和舞台的扫描单元，检测光学系统和光电检测器。 光调制元件和中继光学系统设置在光源的聚光光学系统侧，并且只有振幅改变的调制信号被输入到光调制元件，并且光调制元件被定位成使得照明 相对于预定幅度的调制信号从光调制元件出射的光与会聚光学系统的光轴重合，会聚光学系统的光瞳位置和光调制元件的位置是 通过至少中继光学系统共轭。