公开(公告)号：US20230192931A1

公开(公告)日：2023-06-22

申请号：US16490090

申请日：2018-03-01

Applicant: Osaka University

Inventor： Akira Harada ,  Hiroyasu Yamaguchi ,  Yoshinori Takashima ,  Suguru Nomimura ,  Hikaru Aramoto ,  Ryohei Ikura ,  Yuichiro Kobayashi ,  Yukie Nakamitsu

IPC: C08F251/00 ,  C08B37/16

CPC classification number: C08F251/00 ,  C08B37/0012 ,  C08F2800/10

Abstract: Provided are a host-group-containing polymerizable monomer usable as a starting material for producing a macromolecular material with a high degree of freedom in material design, and excellent toughness and strength; a macromolecular material produced using the host-group-containing polymerizable monomer; and a method for producing the macromolecular material. The host-group-containing polymerizable monomer according to the present invention is a host-group-containing polymerizable monomer, and the host group is a monovalent group formed by removing one hydrogen atom or hydroxy group from a cyclodextrin derivative. The cyclodextrin derivative has such a structure that the hydrogen atom of at least one hydroxy group of a cyclodextrin is replaced with a group selected from the group consisting of a hydrocarbon group, an acyl group, and —CONHR wherein R represents a methyl group or an ethyl group.

公开(公告)号：US20190225936A1

公开(公告)日：2019-07-25

申请号：US16320622

申请日：2017-07-25

Applicant: Osaka University ,  Kyoto University

Inventor： Akira Harada ,  Yoshinori Takashima ,  Masaki Nakahata ,  Motomu Tanaka ,  Marcel Hoerning

IPC: C12N5/00

Abstract: Provided are: a polymer gel for a medium, and a medium in which the stiffness of the polymer gel can be easily and reversibly changed and the shape of cells can be controlled according to the stiffness of the gel; and a method for culturing cells using the medium. The polymer gel for a medium contains a solvent and a crosslinked structure that is crosslinked by reversible bonds. The stiffness of the polymer gel for a medium can be easily and reversibly changed. Accordingly, when the polymer gel for a medium according to the present invention is used, cell morphology and function can be reversibly controlled according to the stiffness of the gel.

公开(公告)号：US10174172B2

公开(公告)日：2019-01-08

申请号：US14914455

申请日：2014-08-27

Applicant: Osaka University

Inventor： Akira Harada ,  Hiroyasu Yamaguchi ,  Akihito Hashidzume ,  Yoshinori Takashima ,  Tomoko Sekine ,  Yuichiro Kobayashi ,  Masaki Nakahata

IPC: C08G81/02 ,  C08J5/12 ,  C12N9/96 ,  C09J5/00

Abstract: The present invention provides a joined body with no risk of detachment from the joining surface without using an adhesive, and a method for producing the joined body. The present invention also provides a reversible joined body that enables control of joining and dissociation, and a method for producing the reversible joined body. In the joined body, a chemical bond is formed between two or more same or different solid-state materials at their contact interfaces by a chemical reaction.

公开(公告)号：US20180133986A1

公开(公告)日：2018-05-17

申请号：US15564083

申请日：2016-04-08

Applicant: Osaka University

Inventor： Akira Harada ,  Yoshinori Takashima ,  Masaki Nakahata

IPC: B29C73/18 ,  C08F2/10 ,  C08F2/46 ,  C08F16/02 ,  C08F22/10 ,  C08F22/38

CPC classification number: B29C73/18 ,  C08F2/10 ,  C08F2/46 ,  C08F4/40 ,  C08F16/02 ,  C08F22/105 ,  C08F22/38 ,  C08F220/58 ,  C08L33/26 ,  C08F220/54 ,  C08F220/56

Abstract: The present invention provides a self-repairing material having self-repairing properties and shape memory properties, as well as high dynamic strength, and also provides a method for manufacturing the same. The self-repairing material of the present invention comprises a polymer comprising specific monomer units in specific ratios, and the concentration of the monomer units is within a specific range.

公开(公告)号：US20170233533A1

公开(公告)日：2017-08-17

申请号：US15322826

申请日：2015-06-19

Applicant: Osaka University

Inventor： Akira Harada ,  Yoshinori Takashima ,  Yuichiro Kobayashi ,  Masaki Nakahata ,  Shoko Mori

IPC: C08G83/00

CPC classification number: C08G83/007 ,  C08G65/33306 ,  C08G65/3346 ,  C08G65/337 ,  C08L101/00

Abstract: Provided is a self-restoring macromolecular material that not only has excellent stress relaxation but that can also be easily restored to its original state, even when damaged or severed. Also provided is a method for producing the self-restoring macromolecular material. The self-restoring macromolecular material contains a crosslinked structure that is formed by crosslinking a polymer containing at least a polyrotaxane molecule. The polyrotaxane molecule is formed so as to include a cyclic molecule 21 and a linear molecule that passes through an opening 21a of the cyclic molecule. The crosslinked structure 1 is crosslinked via a reversible bond between the cyclic molecule of the polyrotaxane molecule and a polymer molecule other than the polyrotaxane molecule.

公开(公告)号：US12054571B2

公开(公告)日：2024-08-06

申请号：US16490090

申请日：2018-03-01

Applicant: Osaka University

Inventor： Akira Harada ,  Hiroyasu Yamaguchi ,  Yoshinori Takashima ,  Suguru Nomimura ,  Hikaru Aramoto ,  Ryohei Ikura ,  Yuichiro Kobayashi ,  Yukie Nakamitsu

IPC: C08F251/00 ,  C08B37/00 ,  C08B37/16

CPC classification number: C08F251/00 ,  C08B37/0012 ,  C08F2800/10

Abstract: Provided are a host-group-containing polymerizable monomer usable as a starting material for producing a macromolecular material with a high degree of freedom in material design, and excellent toughness and strength; a macromolecular material produced using the host-group-containing polymerizable monomer; and a method for producing the macromolecular material. The host-group-containing polymerizable monomer according to the present invention is a host-group-containing polymerizable monomer, and the host group is a monovalent group formed by removing one hydrogen atom or hydroxy group from a cyclodextrin derivative. The cyclodextrin derivative has such a structure that the hydrogen atom of at least one hydroxy group of a cyclodextrin is replaced with a group selected from the group consisting of a hydrocarbon group, an acyl group, and —CONHR wherein R represents a methyl group or an ethyl group.

公开(公告)号：US11472903B2

公开(公告)日：2022-10-18

申请号：US16612046

申请日：2018-05-11

Applicant: Osaka University

Inventor： Akira Harada ,  Hiroyasu Yamaguchi ,  Yoshinori Takashima ,  Tomoko Tokuhara ,  Suguru Nomimura ,  Hikaru Aramoto ,  Ryohei Ikura ,  Nanami Okano

IPC: C08F220/58 ,  C08F251/00 ,  C09D4/06

Abstract: Provided are a composition for polymerization from which a macromolecular material that contains a host-group-introduced polymer with excellent energy to failure can be produced without using a solvent; a polymer of the composition; and a method for producing the polymer. The composition for polymerization contains a solution containing a first polymerizable compound and a host-group-containing polymerizable compound that is dissolved in the first polymerizable compound, wherein the host group present in the host-group-containing polymerizable compound is a group formed by removing one hydrogen atom or hydroxy group from a cyclodextrin, and wherein the cyclodextrin is at least one cyclodextrin selected from the group consisting of α-cyclodextrin, β-cyclodextrin, and γ-cyclodextrin.

公开(公告)号：US20220153934A1

公开(公告)日：2022-05-19

申请号：US17434600

申请日：2020-03-06

Applicant: Osaka University ,  Yushiro Chemical Industry Co., Ltd.

Inventor： Akira Harada ,  Hiroyasu Yamaguchi ,  Yoshinori Takashima ,  Motofumi Osaki ,  Yasumasa Ohashi ,  Hiroaki Takahashi ,  Hidenori Shirakawa

IPC: C08G83/00

Abstract: Provided is a macromolecular material that has self-healing properties, excellent stretchability, and a high degree of freedom in the design of stretchability, strength, and hardness, and that can be produced by a simple method; and also provided is a method for producing the same. The macromolecular material of the present invention comprises a polymer having a host group and a guest group. The host group is a monovalent group formed by removing one hydrogen atom or hydroxy group from a cyclodextrin derivative. The polymer is a polymer of a monomer mixture containing a host group-containing polymerizable monomer, a guest group-containing polymerizable monomer, and a third polymerizable monomer, and the third polymerizable monomer contains a (meth)acrylic ester compound. The host group-containing polymerizable monomer and the guest group-containing polymerizable monomer have a property of being dissolved in the third polymerizable monomer.

公开(公告)号：US11198749B2

公开(公告)日：2021-12-14

申请号：US16326957

申请日：2017-08-23

Applicant: DAIKIN INDUSTRIES, LTD. ,  OSAKA UNIVERSITY

Inventor： Akira Harada ,  Hiroyasu Yamaguchi ,  Yoshinori Takashima ,  Suguru Nomimura ,  Hikaru Aramoto ,  Ryohei Ikura ,  Masaki Nakahata ,  Kazuhisa Iwaso ,  Kentarou Hiraga ,  Akinari Sugiyama ,  Fumihiko Yamaguchi ,  Takashi Nomura

IPC: C08F220/56 ,  C08F290/12 ,  C08L33/06 ,  C09D133/00 ,  C09D201/04 ,  C08L101/02 ,  C08F251/00 ,  C08F220/18 ,  C08J3/11 ,  C09D133/06 ,  C09D133/26 ,  C09K3/10 ,  B01D39/16

Abstract: An object of the present invention is to provide a macromolecular material that exhibits excellent elongation. The first macromolecular material of the present invention contains the first polymer containing the first structural unit and the second polymer containing the second structural unit. The first structural unit has a guest group in its side chain, and the second structural unit has a host group in its side chain. At least one of the first and the second polymers contains at least one fluorine group. The second macromolecular material of the present invention contains the first structural unit having a guest group in its side chain, the second structural unit having a host group in its side chain, and the third structural unit other than the first and second structural units. At least one of the first, the second, and the third structural units contains at least one fluorine group.

公开(公告)号：US20210363338A1

公开(公告)日：2021-11-25

申请号：US17325471

申请日：2021-05-20

Applicant: Osaka University

Inventor： Yoshinori Takashima ,  Akira Harada ,  Motofumi Osaki ,  Kensaku Takahashi ,  Junsu Park

IPC: C08L25/06 ,  C08L5/16

Abstract: An object is to provide a macromolecular composite material that can be produced by a simple process, and that has excellent mechanical properties. The macromolecular composite material of the present invention contains a polymer component and a cyclodextrin compound, the polymer component containing a thermoplastic resin, and the cyclodextrin compound being at least one member selected from the group consisting of cyclodextrin and cyclodextrin derivatives. The macromolecular composite material of the present invention can be produced by a simple process, and has excellent mechanical properties.