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公开(公告)号：US20230233608A1
公开(公告)日：2023-07-27
申请号：US17888808
申请日：2022-08-16
发明人： Peter Barrett , Michael N. Gladstone , Tariq A. Kassum , Vipin Suri , Dan Jun Li , Dexue Sun , Brian Dolinski
CPC分类号： A61K35/17 , C07K14/5443 , C07K14/5434
摘要： The present invention provides regulatable biocircuit systems. Such systems provide modular and tunable protein expression systems in support of the discovery and development of therapeutic modalities.
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公开(公告)号：US20230092895A1
公开(公告)日：2023-03-23
申请号：US17753320
申请日：2019-08-30
发明人： Vipin Suri , Michael Joseph Briskin , Brian Dolinski , Kutlu Goksu Elpek , Tucker Ezell , Scott Francis Heller , Mara Christine Inniss , Tariq A. Kassum , Nicole Kosmider , Abhishek Kulkarni , Meghan Langley , Dan Jun Li , Michelle Lynn Ols , Benjamin J. Primack , Celeste Richardson , Steven Mark Shamah , James Storer , Dexue Sun , Vijaya Balakrishnan , Andrew R.M. Bradbury , Michael Frank Erasmus , Fortunato Ferrara
IPC分类号： C12N9/06 , C07K16/28 , C07K14/54 , C07K14/715 , C07K14/725 , A61K35/17
摘要： The present invention provides biocircuit systems, effector modules and compositions for cancer immunotherapy. Methods for inducing anti-cancer immune responses in a subject are also provided.
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公开(公告)号：US20230074330A1
公开(公告)日：2023-03-09
申请号：US17649592
申请日：2022-02-01
发明人： Vipin Suri , Byron Delabarre , Michael N. Gladstone , Celeste Richardson , Brian Dolinski , Abhishek Kulkarni , Mara Christine Inniss , Dexue Sun , Dan Jun Li , Grace Y. Olinger , Scott Francis Heller
IPC分类号： A61K38/46 , A61P35/00 , A61K31/4985 , A61K35/17 , A61K38/17 , A61K38/20 , A61K39/395 , C07K14/54 , C07K14/725 , C07K14/705 , C07K14/715 , C07K16/28 , C12N9/16
摘要： The present invention relates to compositions and methods for the regulated and controlled expression of proteins. Methods for inducing anti-cancer immune responses in a subject are also provided.
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公开(公告)号：US12104178B2
公开(公告)日：2024-10-01
申请号：US17646212
申请日：2021-12-28
发明人： Vipin Suri , Dan Jun Li , Dexue Sun , Byron Delabarre , Vijaya Balakrishnan , Brian Dolinski , Mara Christine Inniss , Grace Y. Olinger
IPC分类号： A61K35/17 , C07K14/54 , C07K14/705 , C07K14/715 , C12N9/06 , C12N15/85 , C12N15/86
CPC分类号： C12N9/003 , A61K35/17 , C07K14/5434 , C07K14/5443 , C07K14/70503 , C07K14/7155 , C12N15/85 , C12Y105/01003 , C07K2319/30 , C07K2319/33
摘要： The present invention is related to compositions and methods for the regulated and controlled expression of proteins.
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公开(公告)号：US11446398B2
公开(公告)日：2022-09-20
申请号：US16092829
申请日：2017-04-11
发明人： Peter Barrett , Michael N. Gladstone , Tariq A. Kassum , Vipin Suri , Dan Jun Li , Dexue Sun , Brian Dolinski
IPC分类号： A61K38/52 , C12N9/90 , A61K48/00 , C07K16/28 , C07K14/00 , A61P3/08 , A61K35/17 , C07K14/195 , C07K14/54 , C07K14/605 , C07K14/725 , C07K14/705 , C12N5/0789 , C12N9/22 , C12N9/00 , C12N15/11 , A61K38/00
摘要： The present invention provides regulatable biocircuit systems. Such systems provide modular and tunable protein expression systems in support of the discovery and development of therapeutic modalities.
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公开(公告)号：US11241485B2
公开(公告)日：2022-02-08
申请号：US16621593
申请日：2018-06-12
发明人： Vipin Suri , Byron Delabarre , Michael N. Gladstone , Celeste Richardson , Brian Dolinski , Abhishek Kulkarni , Mara Christine Inniss , Dexue Sun , Dan Jun Li , Grace Y. Olinger , Scott Francis Heller
IPC分类号： A61K38/46 , A61P35/00 , A61K31/4985 , A61K35/17 , A61K38/17 , A61K38/20 , A61K39/395 , C07K14/54 , C07K14/725 , C07K14/705 , C07K14/715 , C07K16/28 , C12N9/16 , A61K39/00 , A61P37/04 , C07K19/00
摘要： The present invention relates to compositions and methods for the regulated and controlled expression of proteins. Methods for inducing anti-cancer immune responses in a subject are also provided.
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公开(公告)号：US11666642B2
公开(公告)日：2023-06-06
申请号：US17649592
申请日：2022-02-01
发明人： Vipin Suri , Byron Delabarre , Michael N. Gladstone , Celeste Richardson , Brian Dolinski , Abhishek Kulkarni , Mara Christine Inniss , Dexue Sun , Dan Jun Li , Grace Y. Olinger , Scott Francis Heller
IPC分类号： A61K38/46 , A61P35/00 , A61K31/4985 , A61K35/17 , A61K38/17 , A61K38/20 , A61K39/395 , C07K14/54 , C07K14/725 , C07K14/705 , C07K14/715 , C07K16/28 , C12N9/16 , A61K39/00 , A61P37/04 , C07K19/00
CPC分类号： A61K38/465 , A61K31/4985 , A61K35/17 , A61K38/177 , A61K38/1774 , A61K38/1793 , A61K38/2086 , A61K39/3955 , A61P35/00 , C07K14/5443 , C07K14/7051 , C07K14/70517 , C07K14/70578 , C07K14/7155 , C07K16/2803 , C12N9/16 , C12Y301/04035 , A61K2039/505 , C07K2317/53 , C07K2317/622 , C07K2319/02 , C07K2319/03 , C07K2319/30 , C07K2319/33
摘要： The present invention relates to compositions and methods for the regulated and controlled expression of proteins. Methods for inducing anti-cancer immune responses in a subject are also provided.
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公开(公告)号：US11629340B2
公开(公告)日：2023-04-18
申请号：US16558224
申请日：2019-09-02
发明人： Vipin Suri , Dan Jun Li , Dexue Sun , Byron Delabarre , Vijaya Balakrishnan , Brian Dolinski , Mara Christine Inniss , Grace Y. Olinger
IPC分类号： C12N15/85 , C07K14/54 , A61K35/17 , C12N9/06 , C07K14/715 , C07K14/705
摘要： The present invention is related to compositions and methods for the regulated and controlled expression of proteins.
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公开(公告)号：US20190192691A1
公开(公告)日：2019-06-27
申请号：US16092829
申请日：2017-04-11
发明人： Peter Barrett , Michael N. Gladstone , Tariq A. Kassum , Vipin Suri , Dan Jun Li , Dexue Sun , Brian Dolinski
IPC分类号： A61K48/00 , A61K35/17 , A61P3/08 , C07K14/605 , C12N15/11 , C12N9/22 , C12N5/0789 , C07K14/195 , C07K14/54 , C12N9/00 , C07K16/28 , C07K14/705 , C07K14/725
CPC分类号： A61K48/0066 , A61K35/17 , A61K38/00 , A61P3/08 , C07K14/00 , C07K14/195 , C07K14/5428 , C07K14/5443 , C07K14/605 , C07K14/7051 , C07K14/70517 , C07K14/70578 , C07K16/2803 , C07K2317/622 , C07K2319/00 , C07K2319/03 , C07K2319/30 , C07K2319/31 , C07K2319/50 , C12N5/0647 , C12N9/22 , C12N9/93 , C12N15/11 , C12N2310/20 , C12N2501/125 , C12N2501/145 , C12N2501/22 , C12N2501/2303 , C12N2501/2316 , C12N2800/80 , C12Y603/04016
摘要： The present invention provides regulatable biocircuit systems. Such systems provide modular and tunable protein expression systems in support of the discovery and development of therapeutic modalities.
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