公开(公告)号：US06334871B1

公开(公告)日：2002-01-01

申请号：US08697989

申请日：1996-09-03

申请人： Ofer Dor ,  Amir Loshakove ,  Oren Globerman ,  Mordechay Beyar ,  Rafael Beyar

发明人： Ofer Dor ,  Amir Loshakove ,  Oren Globerman ,  Mordechay Beyar ,  Rafael Beyar

IPC分类号： A61F206

CPC分类号： A61F2/915 ,  A61B90/39 ,  A61F2/91 ,  A61F2002/91583 ,  A61F2230/0013 ,  A61F2240/001 ,  A61F2250/0098

摘要： Stents which are inserted into a body lumen preferably are made of materials which are not radiopaque enough, such as stainless steel 316L. X-ray visualization of a stent enables an accurate positioning of the stent and also a follow-up of its functioning within the patient's body. The radiopaque markers described here are rivets made of a material which is more radiopaque than the stent substance so the location of the stent can be identified. Preferably the stents are heat treated so that atoms from the stent material migrate into the marker material and vice versa.

摘要翻译： 插入体腔的支架优选由不能不透射线的材料制成，例如不锈钢316L。 支架的X射线可视化使得支架的精确定位以及其在患者体内的功能的随访。 这里描述的不透射线标记是由比支架物质更不透射线的材料制成的铆钉，因此可以识别支架的位置。 优选地，支架被热处理，使得来自支架材料的原子迁移到标记材料中，反之亦然。

公开(公告)号：US06371979B1

公开(公告)日：2002-04-16

申请号：US08803324

申请日：1997-02-21

申请人： Mordechay Beyar ,  Oren Globerman ,  Rafael Beyar

发明人： Mordechay Beyar ,  Oren Globerman ,  Rafael Beyar

IPC分类号： A61F206

CPC分类号： A61F2/88 ,  A61F2002/9511 ,  A61F2210/0004 ,  A61F2210/0019

摘要： This invention is directed to a stent delivery system for implanting a flexible, generally cylindrical, expandable, coiled stent. The system comprises a catheter defining at least one lumen and having at least two longitudinally displaced openings or sets of openings ,a flexible, self-expandable coiled stent having discrete proximal and distal end sections, said stent being wound circumferentially around said catheter and coils of the stent being more closely wound at the proximal and/or distal end sections, and one or two release wires cooperating with restraining means so that as the release wire or wires are with-drawn proximally, the proximal and distal end sections of the stent are released in such a manner that coils of the stent unwind and the length of the unwound stent is not substantially less than the length of the portion of the unreleased stent that is not more closely wound.

摘要翻译： 本发明涉及用于植入柔性的，大致圆柱形的，可扩张的盘绕支架的支架输送系统。 该系统包括限定至少一个内腔并具有至少两个纵向移位的开口或组的开口的导管，具有分立的近端和远端部分的柔性自扩张型卷曲支架，所述支架围绕所述导管周向缠绕， 所述支架在近端部分和/或远端部分更紧密地缠绕，以及一个或两个释放线与约束装置配合，使得当释放线或线被向近侧拉伸时，支架的近端部分和远端部分 以这样一种方式释放支架退卷的线圈和未展开的支架的长度基本上不小于未紧密缠绕的未发行支架的部分的长度。

公开(公告)号：US06287336B1

公开(公告)日：2001-09-11

申请号：US09101705

申请日：1999-05-13

申请人： Oren Globerman ,  Mordechay Beyar ,  Rafael Beyar

发明人： Oren Globerman ,  Mordechay Beyar ,  Rafael Beyar

IPC分类号： A61F200

CPC分类号： A61F2/91 ,  A61F2/88 ,  A61F2/90 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/065 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/9155 ,  A61F2002/91583 ,  A61F2250/0018 ,  A61F2250/0019 ,  A61F2250/0029 ,  A61F2250/0039

摘要： A stent (1) is provided for having variable flexibility and stiffness along its length. The stent (1) comprises portions (5, 7, 9, 11, 13, 15) of the stent having different bending and durability characteristics, and may be fabricated, using any of a variety of methods out of any of a variety of materials.

摘要翻译： 提供了一种支架（1），用于沿其长度具有可变的柔性和刚度。 支架（1）包括具有不同弯曲和耐久性特征的支架的部分（5,7,9,11,13,15），并且可以使用各种各样的材料中的任何一种方法制造 。

公开(公告)号：US6090115A

公开(公告)日：2000-07-18

申请号：US136249

申请日：1998-08-19

申请人： Rafael Beyar ,  Oren Globerman ,  Mordechay Beyar

发明人： Rafael Beyar ,  Oren Globerman ,  Mordechay Beyar

IPC分类号： A61B17/12 ,  A61F2/00 ,  A61F2/06 ,  A61F2/84 ,  A61F2/88 ,  A61B17/00

CPC分类号： A61F2/88 ,  A61F2/95 ,  A61B2017/1205 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2250/0059

摘要： This application is directed to a stent delivery system for introducing a flexible, generally cylindrical, self-expandable stent. The system comprises a catheter having distal and proximal ends, the catheter defining at least one lumen extending therethrough and having at least three longitudinally displaced openings or sets of openings extending from a lumen to the surface of the catheter; a stent which comprises a generally cylindrical, expandable structure having proximal and distal ends and a flexible member extending proximally from the proximal end of the structure, the stent being wound circumferentially around the catheter, and having restraining members holding each of the proximal and distal ends of the stent to the catheter, and one or more restraining members holding at least a portion of the flexible member to the catheter surface; and one or two release wires positioned in and extending longitudinally through at least one lumen, the release wires cooperating with the restraining members so that as the release wire or wires are withdrawn proximally, the proximal and distal end sections of the stent are released in such a manner that coils of the stent unwind.

摘要翻译： 本申请涉及一种用于引入柔性的，大致圆柱形的自扩张支架的支架输送系统。 所述系统包括具有远端和近端的导管，所述导管限定延伸穿过其中的至少一个内腔，并且具有至少三个纵向移位的开口或一组开口，其从内腔延伸到导管的表面; 支架，其包括具有近端和远端的大致圆柱形的可扩张结构，以及从所述结构的近端向近侧延伸的柔性构件，所述支架围绕所述导管周向缠绕，并且具有保持每个所述近端和远端的约束构件 以及一个或多个限制构件，其将所述柔性构件的至少一部分保持在所述导管表面上; 以及一个或两个释放线定位在纵向延伸穿过至少一个内腔，所述释放线与限制构件协作，使得当释放线或线在近侧被拉出时，支架的近端部分和远端部分以这样的方式释放 支架放卷的方式。

公开(公告)号：US06371953B1

公开(公告)日：2002-04-16

申请号：US09551479

申请日：2000-04-18

申请人： Rafael Beyar ,  Oren Globerman ,  Mordechay Beyar

发明人： Rafael Beyar ,  Oren Globerman ,  Mordechay Beyar

IPC分类号： A61M2900

CPC分类号： A61F2/88 ,  A61B2017/1205 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2250/0059

摘要： This application is directed to a stent delivery system for introducing a flexible, generally cylindrical, self-expandable stent. The system comprises a catheter having distal and proximal ends, the catheter defining at least one lumen extending therethrough and having at least three longitudinally displaced openings or sets of openings extending from a lumen to the surface of the catheter; a stent which comprises a generally cylindrical, expandable structure having proximal and distal ends and a flexible member extending proximally from the proximal end of the structure, the stent being wound circumferentially around the catheter, and having restraining means holding each of the proximal and distal ends of the stent to the catheter, and one or more restraining means holding at least a portion of the flexible member to the catheter surface; and one or two release wires positioned in and extending longitudinally through at least one lumen, the release wires cooperating with the restraining means so that as the release wire or wires are withdrawn proximally, the proximal and distal end sections of the stent are released in such a manner that coils of the stent unwind.

摘要翻译： 本申请涉及用于引入柔性的，大致圆柱形的自扩张支架的支架输送系统。 所述系统包括具有远端和近端的导管，所述导管限定延伸穿过其中的至少一个内腔，并且具有至少三个纵向移位的开口或一组开口，其从内腔延伸到导管的表面; 支架，其包括具有近端和远端的大致圆柱形的可扩张结构，以及从所述结构的近端向近侧延伸的柔性构件，所述支架围绕导管周向地缠绕，并且具有保持每个近端和远端的约束装置 以及将至少一部分柔性构件保持在导管表面上的一个或多个约束装置; 和一个或两个释放线定位在纵向延伸穿过至少一个内腔，释放线与限制装置配合，使得随着释放线或线在近侧被撤回，支架的近端部分和远端部分以这样的方式释放 支架放卷的方式。

公开(公告)号：US5964771A

公开(公告)日：1999-10-12

申请号：US472464

申请日：1995-06-07

申请人： Rafael Beyar ,  Oren Globerman ,  Mordechay Beyar

发明人： Rafael Beyar ,  Oren Globerman ,  Mordechay Beyar

IPC分类号： A61F2/00 ,  A61F2/88 ,  A61F2/95 ,  A61F11/00 ,  A61M29/00

CPC分类号： A61F2/95 ,  A61F2/88 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2250/0059

摘要： This application is directed to a stent delivery system for introducing a flexible, generally cylindrical, self-expandable stent. The system comprises a catheter having distal and proximal ends, the catheter defining at least one lumen extending there-through and having at least three longitudinally displaced openings or sets of openings extending from a lumen to the surface of the catheter; a stent which comprises a generally cylindrical, expandable structure having proximal and distal ends and a flexible member extending proximally from the proximal end of the structure, the stent being wound circumferentially around the catheter, and having restraining member holding each of the proximal and distal ends of the stent to the catheter, and one or more restraining member holding at least a portion of the flexible member to the catheter surface; and one or two release wires positioned in and extending longitudinally through at least one lumen, the release wires cooperating with the restraining member so that as the release wire or wires are withdrawn proximally, the proximal and distal end sections of the stent are released in such a manner that coils of the stent unwind.

摘要翻译： 本申请涉及用于引入柔性的，大致圆柱形的自扩张支架的支架输送系统。 所述系统包括具有远端和近端的导管，所述导管限定在其中延伸的至少一个腔，并且具有从内腔延伸到导管表面的至少三个纵向移位的开口或一组开口; 支架，其包括具有近端和远端的大致圆柱形的可扩张结构，以及从所述结构的近端向近侧延伸的柔性构件，所述支架围绕所述导管周向地缠绕，并且具有保持每个所述近端和远端的约束构件 以及一个或多个限制构件，其将所述柔性构件的至少一部分保持在所述导管表面上; 以及一个或两个释放线，其位于并且纵向延伸通过至少一个内腔，所述释放线与所述约束构件协作，使得当所述释放线或线被近端拉出时，所述支架的近端部分和远端部分被释放在 支架放卷的方式。

公开(公告)号：US06402777B1

公开(公告)日：2002-06-11

申请号：US09643393

申请日：2000-08-22

申请人： Oren Globerman ,  Mordechay Beyar ,  Rafael Beyar

发明人： Oren Globerman ,  Mordechay Beyar ,  Rafael Beyar

IPC分类号： A61F206

CPC分类号： A61F2/915 ,  A61B90/39 ,  A61F2/91 ,  A61F2002/91533 ,  A61F2002/91583 ,  A61F2240/001 ,  A61F2250/0098

摘要： Stents which are inserted into a body lumen preferably are made of materials which are not radiopaque enough, such as S.S. 316L. X-ray visualization of a stent enables an accurate positioning of the stent and also a follow-up of its functioning within the patient's body. The radiopaque markers described here are rivets made of a material which is more radiopaque than the stent substance so the location of the stent can be identified.

摘要翻译： 插入体腔的支架优选由不透射线不足的材料制成，例如S.S. 316L。 支架的X射线可视化使得支架的精确定位以及其在患者体内的功能的随访。 这里描述的不透射线标记是由比支架物质更不透射线的材料制成的铆钉，因此可以识别支架的位置。

公开(公告)号：US08257302B2

公开(公告)日：2012-09-04

申请号：US11920209

申请日：2005-05-10

申请人： Rafael Beyar ,  Doron Linder ,  Eyal Zilberberg ,  Tal Wenderow

发明人： Rafael Beyar ,  Doron Linder ,  Eyal Zilberberg ,  Tal Wenderow

IPC分类号： A61M31/00 ,  A61B1/00

CPC分类号： A61B90/11 ,  A61B34/77 ,  A61B2017/00207 ,  A61B2034/301 ,  A61B2034/742 ,  A61B2090/064 ,  A61M25/0133

摘要： A remote control catheterization system comprising: a propelling device, which controllably inserts a flexible, elongate probe into the body of a patient; and a control unit, in communication with the propelling device, and comprising user controls which are operated by a user of the system remote from the patient to control insertion of the probe into the body by the propelling device, wherein the user controls include an intuitive user interface comprising a handle that can be moved longitudinally, forward and back along a longitudinal axis, and also can be moved rotationally, in rotation around the longitudinal axis; the intuitive user interface comprising motion sensors that detect longitudinal motion and rotational motion of the handle and convert them to signals; and signal communication circuitry that communicates the signals to the control unit for commanding the propelling device to move the probe in respective direction and distance as the handle.

摘要翻译： 一种遥控导管系统，包括：推进装置，其可控制地将柔性细长的探针插入患者体内; 以及与所述推进装置通信的控制单元，并且包括由远离患者的系统的用户操作以控制通过推进装置将探针插入身体的用户控制，其中，用户控制包括直观的 用户界面包括可以沿着纵向轴线纵向，前后移动的手柄，并且还可以围绕纵向轴线旋转地旋转移动; 直观的用户界面包括运动传感器，其检测手柄的纵向运动和旋转运动并将其转换成信号; 以及信号通信电路，其将信号传送到控制单元，用于指令推进装置在相应的方向和距离上移动探针作为手柄。

公开(公告)号：US07615042B2

公开(公告)日：2009-11-10

申请号：US10561147

申请日：2005-05-10

申请人： Rafael Beyar ,  Tal Wenderow ,  Doron Linder ,  Eyal Zilberberg

发明人： Rafael Beyar ,  Tal Wenderow ,  Doron Linder ,  Eyal Zilberberg

IPC分类号： A61M31/00

CPC分类号： A61M25/0113 ,  A61B2034/301

摘要： An apparatus for imparting motion from at least one of a plurality of motion sources into linear, rotary, or combined linear and rotary motion of an elongated device, the apparatus comprising a transmission for translating the motion to linear or rotary motion of the elongated device.

摘要翻译： 一种用于将来自多个运动源中的至少一个的运动传递到细长装置的线性，旋转或组合的线性和旋转运动的装置，所述装置包括用于将运动转换为细长装置的线性或旋转运动的传动装置。

公开(公告)号：US20090221958A1

公开(公告)日：2009-09-03

申请号：US11920209

申请日：2005-05-10

申请人： Rafael Beyar ,  Doron Linder ,  Eyal Zilberberg ,  Tal Wenderow

发明人： Rafael Beyar ,  Doron Linder ,  Eyal Zilberberg ,  Tal Wenderow

IPC分类号： A61M25/092 ,  A61F2/84

CPC分类号： A61B90/11 ,  A61B34/77 ,  A61B2017/00207 ,  A61B2034/301 ,  A61B2034/742 ,  A61B2090/064 ,  A61M25/0133

摘要： A remote control catheterization system comprising: a propelling device, which controllably inserts a flexible, elongate probe into the body of a patient; and a control unit, in communication with the propelling device, and comprising user controls which are operated by a user of the system remote from the patient to control insertion of the probe into the body by the propelling device, wherein the user controls include an intuitive user interface comprising a handle that can be moved longitudinally, forward and back along a longitudinal axis, and also can be moved rotationally, in rotation around the longitudinal axis; the intuitive user interface comprising motion sensors that detect longitudinal motion and rotational motion of the handle and convert them to signals; and signal communication circuitry that communicates the signals to the control unit for commanding the propelling device to move the probe in respective direction and distance as the handle.

摘要翻译： 一种遥控导管系统，包括：推进装置，其可控制地将柔性细长的探针插入患者体内; 以及与所述推进装置通信的控制单元，并且包括由远离患者的系统的用户操作以控制通过推进装置将探针插入身体的用户控制，其中，用户控制包括直观的 用户界面包括可以沿着纵向轴线纵向，前后移动的手柄，并且还可以围绕纵向轴线旋转地旋转移动; 直观的用户界面包括运动传感器，其检测手柄的纵向运动和旋转运动并将其转换成信号; 以及信号通信电路，其将信号传送到控制单元，用于指令推进装置在相应的方向和距离上移动探针作为手柄。